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1. Full Text HTLV-1 infection and adult T-cell leukemia/ lymphoma-A tale of two proteins: Tax and HBZ
by Giam, Chou-Zen and Semmes, Oliver John
Viruses, ISSN 1999-4915, 06/2016, Volume 8, Issue 6, p. 161
Senescence | Adult T-cell leukemia | UBC13 | DNA damage response | RNF8 | Latency and persistence | HTLV-1 | K63-linked polyubiquitin | Genomic instability | Life Sciences & Biomedicine | Science & Technology | Virology | Host-Pathogen Interactions | Basic-Leucine Zipper Transcription Factors - metabolism | Gene Products, tax - metabolism | Retroviridae Proteins - metabolism | Virus Replication | Virus Latency | Humans | Human T-lymphotropic virus 1 - pathogenicity | Leukemia-Lymphoma, Adult T-Cell - pathology | Leukemia-Lymphoma, Adult T-Cell - virology | Carcinogenesis | Index Medicus | senescence | latency and persistence | adult T-cell leukemia | genomic instability
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2. Full Text Clinical significance of CD163+ tumor‐associated macrophages in patients with adult T‐cell leukemia/lymphoma
by Komohara, Yoshihiro and Niino, Daisuke and Saito, Yoichi and Ohnishi, Koji and Horlad, Hasita and Ohshima, Koichi and Takeya, Motohiro
Cancer science, ISSN 1347-9032, 07/2013, Volume 104, Issue 7, pp. 945 - 951
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | Prognosis | Humans | Complement C5a - metabolism | Receptors, Cell Surface - metabolism | Male | Leukemia-Lymphoma, Adult T-Cell - pathology | Receptors, Cell Surface - immunology | Disease Progression | Antigens, CD - metabolism | Leukemia-Lymphoma, Adult T-Cell - immunology | Macrophages - metabolism | Leukemia-Lymphoma, Adult T-Cell - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Chemokine CCL1 - metabolism | Cell Line, Tumor | Female | Aged | Complement C5a - immunology | Chemokine CXCL1 - metabolism | Interleukin-6 - metabolism | Antigens, Differentiation, Myelomonocytic - immunology | Macrophages - immunology | Care and treatment | Lymphomas | T cells | Macrophages | Index Medicus | Original
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3. Full Text Human T-cell lymphotropic virus: A model of NF-κB-associated tumorigenesis
by Qu, Zhaoxia and Xiao, Gutian
Viruses, ISSN 1999-4915, 06/2011, Volume 3, Issue 6, pp. 714 - 749
NF-κB | WWOX | Transformation | PDLIM2 | HTLV | IKK | ATL | Virus-host interaction | Tax | Tumorigenesis | Immune escape | Life Sciences & Biomedicine | Science & Technology | Virology | Leukemia-Lymphoma, Adult T-Cell - genetics | Humans | NF-kappa B - metabolism | Gene Products, tax - genetics | Leukemia-Lymphoma, Adult T-Cell - pathology | Leukemia-Lymphoma, Adult T-Cell - virology | Animals | Gene Products, tax - metabolism | NF-kappa B - genetics | Cell Transformation, Neoplastic | Leukemia-Lymphoma, Adult T-Cell - metabolism | Models, Biological | Human T-lymphotropic virus 1 - metabolism | Human T-lymphotropic virus 1 - pathogenicity | Human T-lymphotropic virus 1 - genetics | Index Medicus | virus-host interaction | immune escape | tumorigenesis | transformation
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4. Full Text The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia
by Liu, Yu and Easton, John and Shao, Ying and Maciaszek, Jamie and Wang, Zhaoming and Wilkinson, Mark R and McCastlain, Kelly and Edmonson, Michael and Pounds, Stanley B and Shi, Lei and Zhou, Xin and Ma, Xiaotu and Sioson, Edgar and Li, Yongjin and Rusch, Michael and Gupta, Pankaj and Pei, Deqing and Cheng, Cheng and Smith, Malcolm A and Auvil, Jaime Guidry and Gerhard, Daniela S and Relling, Mary V and Winick, Naomi J and Carroll, Andrew J and Heerema, Nyla A and Raetz, Elizabeth and Devidas, Meenakshi and Willman, Cheryl L and Harvey, Richard C and Carroll, William L and Dunsmore, Kimberly P and Winter, Stuart S and Wood, Brent L and Sorrentino, Brian P and Downing, James R and Loh, Mignon L and Hunger, Stephen P and Zhang, Jinghui and Mullighan, Charles G
Nature genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1211 - 1218
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Epigenesis, Genetic | Genomics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Child, Preschool | Signal Transduction - genetics | Receptor, Notch1 - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Young Adult | Cell Lineage | Gene Rearrangement | Adolescent | Adult | Mutation | Child | Cohort Studies | Physiological aspects | Development and progression | Genetic aspects | Research | Acute lymphocytic leukemia | T cells | Deregulation | Transcription factors | Leukemia | Genes | Genomes | Lymphocytes T | Kinases | Inactivation | Gene sequencing | Signal transduction | Pathways | Cyclin-dependent kinase inhibitors | Children | Young adults | Genomic analysis | Acute lymphatic leukemia | Deactivation | HOXA1 protein | INK4 protein | T cell receptors | Lymphatic leukemia | Suppressors | Tlx1 protein | Notch protein | PTEN protein | PTPN2 protein | Index Medicus
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5. Full Text Polycomb-dependent epigenetic landscape in adult T-cell leukemia
by Fujikawa, Dai and Fujikawa, Dai and Nakagawa, Shota and Nakagawa, Shota and Hori, Makoto and Hori, Makoto and Kurokawa, Naoya and Kurokawa, Naoya and Soejima, Ai and Soejima, Ai and Nakano, Kazumi and Nakano, Kazumi and Yamochi, Tadanori and Yamochi, Tadanori and Nakashima, Makoto and Nakashima, Makoto and Kobayashi, Seiichiro and Kobayashi, Seiichiro and Tanaka, Yuetsu and Tanaka, Yuetsu and Iwanaga, Masako and Iwanaga, Masako and Utsunomiya, Atae and Utsunomiya, Atae and Uchimaru, Kaoru and Uchimaru, Kaoru and Yamagishi, Makoto and Yamagishi, Makoto and Watanabe, Toshiki and Watanabe, Toshiki
Blood, ISSN 0006-4971, 04/2016, Volume 127, Issue 14, pp. 1790 - 1802
Life Sciences & Biomedicine | Hematology | Science & Technology | Polycomb Repressive Complex 2 - genetics | Leukemia-Lymphoma, Adult T-Cell - genetics | Epigenesis, Genetic | Humans | Male | Gene Products, tax - genetics | Gene Expression Regulation, Leukemic | Leukemia-Lymphoma, Adult T-Cell - pathology | Neoplasm Proteins - metabolism | Enhancer of Zeste Homolog 2 Protein | Histones - genetics | Gene Products, tax - metabolism | Leukemia-Lymphoma, Adult T-Cell - metabolism | Cell Line, Tumor | Adult | Female | Human T-lymphotropic virus 1 - metabolism | Human T-lymphotropic virus 1 - genetics | Histones - metabolism | Neoplasm Proteins - genetics | Polycomb Repressive Complex 2 - metabolism | Cell Line, Transformed | Index Medicus | Abridged Index Medicus
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6. Full Text Polycomb-Mediated Loss of miR-31 Activates NIK-Dependent NF-κB Pathway in Adult T Cell Leukemia and Other Cancers
by Yamagishi, Makoto and Nakano, Kazumi and Miyake, Ariko and Yamochi, Tadanori and Kagami, Yayoi and Tsutsumi, Akihisa and Matsuda, Yuka and Sato-Otsubo, Aiko and Muto, Satsuki and Utsunomiya, Atae and Yamaguchi, Kazunari and Uchimaru, Kaoru and Ogawa, Seishi and Watanabe, Toshiki
Cancer cell, ISSN 1535-6108, 01/2012, Volume 21, Issue 1, pp. 121 - 135
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Oligonucleotide Array Sequence Analysis | Signal Transduction | Leukemia-Lymphoma, Adult T-Cell - genetics | Protein-Serine-Threonine Kinases - physiology | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Repressor Proteins - genetics | NF-kappa B - metabolism | Gene Expression Profiling | Polycomb-Group Proteins | Repressor Proteins - physiology | NF-kappa B - genetics | T-Lymphocytes - metabolism | Leukemia-Lymphoma, Adult T-Cell - metabolism | MicroRNAs - genetics | T-Lymphocytes - pathology | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | Index Medicus
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7. Full Text Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma
by Nakagawa, Masao and Schmitz, Roland and Xiao, Wenming and Goldman, Carolyn K and Xu, Weihong and Yang, Yandan and Yu, Xin and Waldmann, Thomas A and Staudt, Louis M
The Journal of experimental medicine, ISSN 0022-1007, 2014, Volume 211, Issue 13, pp. 2497 - 2505
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cell Proliferation | Humans | Molecular Sequence Data | Chemokine CCL22 | Phosphatidylinositol 3-Kinases - metabolism | Receptors, CCR4 - metabolism | Endocytosis | Protein Isoforms - metabolism | Protein Isoforms - chemistry | Adult | Proto-Oncogene Proteins c-akt - metabolism | Leukemia-Lymphoma, Adult T-Cell - enzymology | Amino Acid Sequence | Signal Transduction | Leukemia-Lymphoma, Adult T-Cell - genetics | Receptors, CCR4 - genetics | Mutant Proteins - metabolism | Leukemia-Lymphoma, Adult T-Cell - pathology | Mutation - genetics | Chemotaxis | Mutant Proteins - chemistry | Protein Binding | Ligands | Receptors, CCR4 - chemistry | Protein Isoforms - genetics | Index Medicus | Brief Definitive Report
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8. Full Text New mouse model of acute adult T‐cell leukemia generated by transplantation of AKT, BCLxL, and HBZ‐transduced T cells
by Kasugai, Yumiko and Yoshida, Noriaki and Ohshima, Koichi and Matsuo, Keitaro and Seto, Masao and Tsuzuki, Shinobu
Cancer science, ISSN 1347-9032, 08/2016, Volume 107, Issue 8, pp. 1072 - 1078
HBZ | ATL | AKT | mouse model | BCLxL | Life Sciences & Biomedicine | Oncology | Science & Technology | Interleukins | T cells | Analysis | Leukemia | Cytokines | Genes | AKT protein | Lymphocytes T | Transplantation | Kinases | Lymphoma | Plasmids | Lymphocytes | Transgenic animals | Collaboration | Cooperation | Rodents | Ligands | Tumors | Index Medicus | Original
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