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HTLV-1 infection and adult T-cell leukemia/ lymphoma-A tale of two proteins: Tax and HBZ
Viruses, ISSN 1999-4915, 06/2016, Volume 8, Issue 6, p. 161
Senescence | Adult T-cell leukemia | UBC13 | DNA damage response | RNF8 | Latency and persistence | HTLV-1 | K63-linked polyubiquitin | Genomic instability | Life Sciences & Biomedicine | Science & Technology | Virology | Host-Pathogen Interactions | Basic-Leucine Zipper Transcription Factors - metabolism | Gene Products, tax - metabolism | Retroviridae Proteins - metabolism | Virus Replication | Virus Latency | Humans | Human T-lymphotropic virus 1 - pathogenicity | Leukemia-Lymphoma, Adult T-Cell - pathology | Leukemia-Lymphoma, Adult T-Cell - virology | Carcinogenesis | Index Medicus | senescence | latency and persistence | adult T-cell leukemia | genomic instability
Journal Article
Cancer science, ISSN 1347-9032, 07/2013, Volume 104, Issue 7, pp. 945 - 951
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | Prognosis | Humans | Complement C5a - metabolism | Receptors, Cell Surface - metabolism | Male | Leukemia-Lymphoma, Adult T-Cell - pathology | Receptors, Cell Surface - immunology | Disease Progression | Antigens, CD - metabolism | Leukemia-Lymphoma, Adult T-Cell - immunology | Macrophages - metabolism | Leukemia-Lymphoma, Adult T-Cell - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Chemokine CCL1 - metabolism | Cell Line, Tumor | Female | Aged | Complement C5a - immunology | Chemokine CXCL1 - metabolism | Interleukin-6 - metabolism | Antigens, Differentiation, Myelomonocytic - immunology | Macrophages - immunology | Care and treatment | Lymphomas | T cells | Macrophages | Index Medicus | Original
Journal Article
Viruses, ISSN 1999-4915, 06/2011, Volume 3, Issue 6, pp. 714 - 749
NF-κB | WWOX | Transformation | PDLIM2 | HTLV | IKK | ATL | Virus-host interaction | Tax | Tumorigenesis | Immune escape | Life Sciences & Biomedicine | Science & Technology | Virology | Leukemia-Lymphoma, Adult T-Cell - genetics | Humans | NF-kappa B - metabolism | Gene Products, tax - genetics | Leukemia-Lymphoma, Adult T-Cell - pathology | Leukemia-Lymphoma, Adult T-Cell - virology | Animals | Gene Products, tax - metabolism | NF-kappa B - genetics | Cell Transformation, Neoplastic | Leukemia-Lymphoma, Adult T-Cell - metabolism | Models, Biological | Human T-lymphotropic virus 1 - metabolism | Human T-lymphotropic virus 1 - pathogenicity | Human T-lymphotropic virus 1 - genetics | Index Medicus | virus-host interaction | immune escape | tumorigenesis | transformation
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The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia
Nature genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1211 - 1218
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Epigenesis, Genetic | Genomics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Child, Preschool | Signal Transduction - genetics | Receptor, Notch1 - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Young Adult | Cell Lineage | Gene Rearrangement | Adolescent | Adult | Mutation | Child | Cohort Studies | Physiological aspects | Development and progression | Genetic aspects | Research | Acute lymphocytic leukemia | T cells | Deregulation | Transcription factors | Leukemia | Genes | Genomes | Lymphocytes T | Kinases | Inactivation | Gene sequencing | Signal transduction | Pathways | Cyclin-dependent kinase inhibitors | Children | Young adults | Genomic analysis | Acute lymphatic leukemia | Deactivation | HOXA1 protein | INK4 protein | T cell receptors | Lymphatic leukemia | Suppressors | Tlx1 protein | Notch protein | PTEN protein | PTPN2 protein | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 04/2016, Volume 127, Issue 14, pp. 1790 - 1802
Life Sciences & Biomedicine | Hematology | Science & Technology | Polycomb Repressive Complex 2 - genetics | Leukemia-Lymphoma, Adult T-Cell - genetics | Epigenesis, Genetic | Humans | Male | Gene Products, tax - genetics | Gene Expression Regulation, Leukemic | Leukemia-Lymphoma, Adult T-Cell - pathology | Neoplasm Proteins - metabolism | Enhancer of Zeste Homolog 2 Protein | Histones - genetics | Gene Products, tax - metabolism | Leukemia-Lymphoma, Adult T-Cell - metabolism | Cell Line, Tumor | Adult | Female | Human T-lymphotropic virus 1 - metabolism | Human T-lymphotropic virus 1 - genetics | Histones - metabolism | Neoplasm Proteins - genetics | Polycomb Repressive Complex 2 - metabolism | Cell Line, Transformed | Index Medicus | Abridged Index Medicus
Journal Article
Cancer cell, ISSN 1535-6108, 01/2012, Volume 21, Issue 1, pp. 121 - 135
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Oligonucleotide Array Sequence Analysis | Signal Transduction | Leukemia-Lymphoma, Adult T-Cell - genetics | Protein-Serine-Threonine Kinases - physiology | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Repressor Proteins - genetics | NF-kappa B - metabolism | Gene Expression Profiling | Polycomb-Group Proteins | Repressor Proteins - physiology | NF-kappa B - genetics | T-Lymphocytes - metabolism | Leukemia-Lymphoma, Adult T-Cell - metabolism | MicroRNAs - genetics | T-Lymphocytes - pathology | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | Index Medicus
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 2014, Volume 211, Issue 13, pp. 2497 - 2505
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cell Proliferation | Humans | Molecular Sequence Data | Chemokine CCL22 | Phosphatidylinositol 3-Kinases - metabolism | Receptors, CCR4 - metabolism | Endocytosis | Protein Isoforms - metabolism | Protein Isoforms - chemistry | Adult | Proto-Oncogene Proteins c-akt - metabolism | Leukemia-Lymphoma, Adult T-Cell - enzymology | Amino Acid Sequence | Signal Transduction | Leukemia-Lymphoma, Adult T-Cell - genetics | Receptors, CCR4 - genetics | Mutant Proteins - metabolism | Leukemia-Lymphoma, Adult T-Cell - pathology | Mutation - genetics | Chemotaxis | Mutant Proteins - chemistry | Protein Binding | Ligands | Receptors, CCR4 - chemistry | Protein Isoforms - genetics | Index Medicus | Brief Definitive Report
Journal Article
Cancer science, ISSN 1347-9032, 08/2016, Volume 107, Issue 8, pp. 1072 - 1078
HBZ | ATL | AKT | mouse model | BCLxL | Life Sciences & Biomedicine | Oncology | Science & Technology | Interleukins | T cells | Analysis | Leukemia | Cytokines | Genes | AKT protein | Lymphocytes T | Transplantation | Kinases | Lymphoma | Plasmids | Lymphocytes | Transgenic animals | Collaboration | Cooperation | Rodents | Ligands | Tumors | Index Medicus | Original
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