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1. Full Text Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012
by Stoll, Barbara J and Hansen, Nellie I and Bell, Edward F and Walsh, Michele C and Carlo, Waldemar A and Shankaran, Seetha and Laptook, Abbot R and Sánchez, Pablo J and Van Meurs, Krisa P and Wyckoff, Myra and Das, Abhik and Hale, Ellen C and Ball, M. Bethany and Newman, Nancy S and Schibler, Kurt and Poindexter, Brenda B and Kennedy, Kathleen A and Cotten, C. Michael and Watterberg, Kristi L and D’Angio, Carl T and DeMauro, Sara B and Truog, William E and Devaskar, Uday and Higgins, Rosemary D and Eunice Kennedy Shriver Natl Inst and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
JAMA, ISSN 0098-7484, 09/2015, Volume 314, Issue 10, pp. 1039 - 1051
IMPORTANCE: Extremely preterm infants contribute disproportionately to neonatal morbidity and mortality. OBJECTIVE: To review 20-year trends in... 
UNITED-STATES | MEDICINE, GENERAL & INTERNAL | ANTENATAL CORTICOSTEROIDS | BIRTH-WEIGHT OUTCOMES | LATE-ONSET SEPSIS | RESEARCH NETWORK | WEEKS GESTATION | NATIONAL-INSTITUTE | NECROTIZING ENTEROCOLITIS | EXTREMELY PREMATURE-INFANTS | CHILD-HEALTH | United States - epidemiology | Continuous Positive Airway Pressure - trends | Humans | Cesarean Section - statistics & numerical data | Male | Infant, Premature, Diseases - mortality | Infant, Premature, Diseases - therapy | Retinopathy of Prematurity - epidemiology | Adrenal Cortex Hormones - therapeutic use | Bronchopulmonary Dysplasia - epidemiology | Intensive Care, Neonatal - statistics & numerical data | Infection - epidemiology | Adult | Female | Continuous Positive Airway Pressure - statistics & numerical data | Infant, Premature, Diseases - epidemiology | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Gestational Age | Enterocolitis, Necrotizing - epidemiology | Pregnancy | Infant, Premature | Survival Analysis | Intracranial Hemorrhages - epidemiology | Cesarean Section - trends | Infant, Extremely Premature | Care and treatment | Infants | Management | Infants (Premature) | Health aspects | Neonatal care | Mortality | Premature birth | Lung diseases | Cesarean section | Morbidity | Steroids
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2. Full Text The Near-Term (Late Preterm) Human Brain and Risk for Periventricular Leukomalacia: A Review
by Kinney, Hannah C
Seminars in Perinatology, ISSN 0146-0005, 2006, Volume 30, Issue 2, pp. 81 - 88
Historically the major focus in neonatal neurology has been on brain injury in premature infants born less than 30 gestational weeks. This focus reflects the... 
axons | oligodendrocytes | periventricular leukomalacia | prematurity | antioxidant enzymes | PREMATURE-INFANT | THALAMOCORTICAL CONNECTIONS | MYELINATION | INJURY | SUBPLATE NEURONS | OLIGODENDROCYTE | OBSTETRICS & GYNECOLOGY | CEREBRAL WHITE-MATTER | SOMATOSENSORY CORTEX | CARDIAC-SURGERY | PEDIATRICS | CENTRAL-NERVOUS-SYSTEM | Leukomalacia, Periventricular - etiology | Antioxidants - metabolism | Humans | Axons - metabolism | Leukomalacia, Periventricular - pathology | Brain - growth & development | Gestational Age | Incidence | Brain - metabolism | Pregnancy | Axons - pathology | Infant, Premature | Brain - pathology | Female | Enzymes - metabolism | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Antioxidants | Brain | Infants (Premature)
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3. Full Text Neuron deficit in the white matter and subplate in periventricular leukomalacia
by Kinney, Hannah C and Haynes, Robin L and Xu, Gang and Andiman, Sarah E and Folkerth, Rebecca D and Sleeper, Lynn A and Volpe, Joseph J
Annals of Neurology, ISSN 0364-5134, 03/2012, Volume 71, Issue 3, pp. 397 - 406
Objective: The cellular basis of cognitive abnormalities in preterm infants with periventricular leukomalacia (PVL) is uncertain. One important possibility is... 
DEVELOPMENTAL HISTORY | HUMAN NEOCORTEX | PYRAMIDAL NEURONS | HUMAN CEREBRAL-CORTEX | SUBCORTICAL LAMINAR HETEROTOPIA | HYPOXIA-ISCHEMIA | BRAIN-INJURY | SELECTIVE VULNERABILITY | EXPRESSION | NEUROSCIENCES | GABAERGIC NEURONS | CLINICAL NEUROLOGY | Neurons - pathology | Cell Count - methods | Nerve Fibers, Myelinated - pathology | Humans | Cerebral Cortex - pathology | Female | Male | Leukomalacia, Periventricular - pathology | Cerebral Cortex - cytology | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Attention deficit disorder | Brain | Neurons | NG2 | hypoxia-ischemia | GABAergic neurons | doublecortin | microtubule-associated protein 2 | subplate
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4. Full Text Brain injury and altered brain growth in preterm infants: Predictors and prognosis
by Kidokoro, Hiroyuki and Anderson, Peter J and Doyle, Lex W and Woodward, Lianne J and Neil, Jeffrey J and Inder, Terrie E
Pediatrics, ISSN 0031-4005, 08/2014, Volume 134, Issue 2, pp. e444 - e453
BACKGROUND: To define the nature and frequency of brain injury and brain growth impairment in very preterm (VPT) infants by using MRI at term-equivalent age... 
Cerebellar hemorrhage | Brain metrics | Intraventricular hemorrhage | Periventricular leukomalacia | MRI | CRANIAL ULTRASOUND | RISK-FACTORS | LOW-BIRTH-WEIGHT | PREMATURE NEWBORNS | brain metrics | cerebellar hemorrhage | SCHOOL-AGE | NECROTIZING ENTEROCOLITIS | periventricular leukomalacia | intraventricular hemorrhage | CHILDREN BORN | PEDIATRICS | OUTCOMES | WHITE-MATTER ABNORMALITIES | CEREBRAL-PALSY | Prognosis | Humans | Intracranial Hemorrhages - pathology | Male | Leukomalacia, Periventricular - pathology | Brain - growth & development | Magnetic Resonance Imaging | Apgar Score | Infant, Premature | Brain - pathology | Intracranial Hemorrhages - epidemiology | Female | Infant, Extremely Premature | Infant, Premature, Diseases - epidemiology | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Infant, Premature, Diseases - pathology | Brain | Complications and side effects | Usage | Child development | Magnetic resonance imaging | Infants (Premature) | Analysis | Outcome and process assessment (Health Care) | Health aspects | Injuries | Babies | Cerebral palsy | Brain damage | Nuclear magnetic resonance--NMR | Cognition & reasoning | Risk factors
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5. Full Text Short-term costs of preeclampsia to the United States health care system
by Stevens, Warren and Shih, Tiffany and Incerti, Devin and Ton, Thanh G.N and Lee, Henry C and Peneva, Desi and Macones, George A and Sibai, Baha M and Jena, Anupam B
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 09/2017, Volume 217, Issue 3, pp. 237 - 248.e16
Preeclampsia is a leading cause of maternal morbidity and mortality and adverse neonatal outcomes. Little is known about the extent of the health and cost... 
health care cost burden | preterm birth | hospital admission | maternal morbidity | perinatal morbidity | preeclampsia | maternal mortality | GLOBAL BURDEN | HYPERTENSIVE DISORDERS | FOLLOW-UP | NECROTIZING ENTEROCOLITIS | PREGNANCY | OBSTETRICS & GYNECOLOGY | CHILD HEALTH | BIRTH-WEIGHT INFANTS | EXTREMELY PRETERM INFANTS | CARDIOVASCULAR-DISEASE | ADJUSTED LIFE-YEAR | Seizures - economics | Thrombocytopenia - epidemiology | Pre-Eclampsia - epidemiology | United States - epidemiology | Humans | Middle Aged | Respiratory Distress Syndrome, Newborn - epidemiology | Infant | Male | Fetal Distress - economics | Bronchopulmonary Dysplasia - epidemiology | Young Adult | Postpartum Hemorrhage - economics | Adult | Female | Retrospective Studies | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Pre-Eclampsia - economics | Sepsis - economics | Sepsis - epidemiology | Fetal Distress - epidemiology | Gestational Age | Cerebral Hemorrhage - economics | Pregnancy | Regression Analysis | Health Care Costs | Cerebral Hemorrhage - epidemiology | Postpartum Hemorrhage - epidemiology | Seizures - epidemiology | Bronchopulmonary Dysplasia - economics | Leukomalacia, Periventricular - economics | Respiratory Distress Syndrome, Newborn - economics | Thrombocytopenia - economics | Cohort Studies | Medical policy | Medical colleges | Preeclampsia | Mortality | Medical care | Bahai Faith | Health aspects | Epidemiology | Medical care, Cost of | Quality management | Patient outcomes | Mothers
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6. Full Text Trends in severe brain injury and neurodevelopmental outcome in premature newborn infants: The role of cystic periventricular leukomalacia
by Hamrick, Shannon E.G and Miller, Steven P and Leonard, Carol and Glidden, David V and Goldstein, Ruth and Ramaswamy, Vijay and Piecuch, Robert and Ferriero, Donna M
The Journal of Pediatrics, ISSN 0022-3476, 11/2004, Volume 145, Issue 5, pp. 593 - 599
To determine if the incidence of sonographically detected cystic periventricular leukomalacia (PVL) and periventricular hemorrhagic infarction (PVHI) have... 
GRAMS | CRANIAL ULTRASOUND | GESTATIONAL-AGE | LOW-BIRTH-WEIGHT | PEDIATRICS | PRETERM INFANTS | TERM | WHITE-MATTER INJURY | CHILDREN | Follow-Up Studies | Motor Skills - physiology | Infant, Very Low Birth Weight | Brain - physiopathology | Humans | Brain - growth & development | Leukomalacia, Periventricular - diagnostic imaging | Cerebral Hemorrhage - diagnostic imaging | Cerebral Infarction - diagnostic imaging | Incidence | Cerebral Infarction - epidemiology | Cerebral Hemorrhage - epidemiology | Echoencephalography | Infant, Premature | Child Development - physiology | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Brain | Infants (Premature) | Injuries
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7. Full Text Patterns of Cerebral Injury and Neurodevelopmental Outcomes After Symptomatic Neonatal Hypoglycemia
by Burns, Charlotte M and Rutherford, Mary A and Boardman, James P and Cowan, Frances M
Pediatrics, ISSN 0031-4005, 07/2008, Volume 122, Issue 1, pp. 65 - 74
BACKGROUND. Symptomatic neonatal hypoglycemia may be associated with later neurodevelopmental impairment. Brain injury patterns identified on early MRI scans... 
Magnetic resonance imaging | Neonatal hypoglycemia | Outcome | DEFINITION | magnetic resonance imaging | ANTAGONIST | BLOOD-FLOW | MR FINDINGS | METABOLISM | GLUCOSE | INFANTS | LACTATE | NEWBORN DOGS | PEDIATRICS | PRETERM | neonatal hypoglycemia | outcome | Hypoglycemia - epidemiology | Blood Glucose - analysis | Humans | Cesarean Section - statistics & numerical data | Infarction, Middle Cerebral Artery - epidemiology | Infant | Male | Head - growth & development | Hypoglycemia - pathology | Leukomalacia, Periventricular - pathology | Pregnancy | Magnetic Resonance Imaging | Nervous System Diseases - epidemiology | Hemiplegia - epidemiology | Seizures - epidemiology | Brain - pathology | Hypertension, Pregnancy-Induced - epidemiology | Female | Child Development | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Neuroimaging | Brain | Patient outcomes | Development | Infants | Research | Hypoglycemia | Injuries | Risk factors | Babies | Brain damage | Nuclear magnetic resonance--NMR | Neurological disorders
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8. Full Text Risk factors for periventricular white matter injury in very low birthweight neonates
by Tsimis, Michael E., MD and Johnson, Clark T., MD and Raghunathan, Radhika S., BS and Northington, Frances J., MD and Burd, Irina, MD, PhD and Graham, Ernest M., MD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2015, Volume 214, Issue 3, pp. 380.e1 - 380.e6
Background The development of periventricular white matter injury (PWMI) in the preterm neonate is the most common insult portending neurologic impairment and... 
Obstetrics and Gynecology | fetal metabolic acidosis | very low birthweight neonates | neonatal infection | PRETERM INFANTS | SEPSIS | DAMAGE | CHILDREN | OBSTETRICS & GYNECOLOGY | MENINGITIS | LEUKOMALACIA | GROWTH | DISABILITY | INFECTION | OUTCOMES | Infant, Very Low Birth Weight | Humans | Risk Factors | Fetal Growth Retardation - epidemiology | Central Nervous System Infections - cerebrospinal fluid | Leukomalacia, Periventricular - diagnostic imaging | Gestational Age | Central Nervous System Infections - epidemiology | Cerebrospinal Fluid - immunology | Pregnancy | Young Adult | Birth Weight | Acidosis - epidemiology | Fetal Blood - chemistry | Ultrasonography | Adult | Female | Leukocyte Count | Cerebrospinal Fluid - microbiology | Leukomalacia, Periventricular - epidemiology | Hydrogen-Ion Concentration | Infants (Newborn) | Cerebral palsy | Medical colleges | Neurosciences | Risk factors | Index Medicus | Abridged Index Medicus
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9. Full Text Randomized Trial of Liberal Versus Restrictive Guidelines for Red Blood Cell Transfusion in Preterm Infants
by Bell, Edward F and Strauss, Ronald G and Widness, John A and Mahoney, Larry T and Mock, Donald M and Seward, Victoria J and Cress, Gretchen A and Johnson, Karen J and Kromer, Irma J and Zimmerman, M. Bridget
Pediatrics, ISSN 0031-4005, 06/2005, Volume 115, Issue 6, pp. 1685 - 1691
Objective. Although many centers have introduced more restrictive transfusion policies for pre-term infants in recent years, the benefits and adverse... 
Erythrocyte | Brain | Transfusions | Anemia | Preterm infants | ERYTHROPOIETIN | preterm infants | ABNORMALITIES | transfusions | PREMATURE-INFANTS | brain | DOPPLER | anemia | INTENSIVE-CARE | erythrocyte | BIRTH-WEIGHT INFANTS | PATTERN | PEDIATRICS | LESS | Anemia - blood | Infant, Very Low Birth Weight | Practice Guidelines as Topic - standards | Humans | Hematocrit | Risk | Infant, Premature, Diseases - therapy | Retinopathy of Prematurity - epidemiology | Bronchopulmonary Dysplasia - epidemiology | Blood Donors | Monitoring, Physiologic | Echoencephalography | Apnea - prevention & control | Cerebral Hemorrhage - prevention & control | Infant, Premature, Diseases - epidemiology | Infant, Newborn | Length of Stay - statistics & numerical data | Leukomalacia, Periventricular - epidemiology | Cerebral Hemorrhage - etiology | Apnea - complications | Erythrocyte Transfusion - statistics & numerical data | Infant, Premature, Diseases - prevention & control | Comorbidity | Leukomalacia, Periventricular - etiology | Infant, Premature, Diseases - etiology | Anemia - therapy | Treatment Outcome | Erythrocyte Transfusion - standards | Leukomalacia, Periventricular - diagnostic imaging | Cerebral Hemorrhage - diagnostic imaging | Oxygen - blood | Brain Damage, Chronic - etiology | Cerebral Hemorrhage - epidemiology | Ductus Arteriosus, Patent - epidemiology | Infant, Premature | Infant, Premature, Diseases - diagnostic imaging | Survival Analysis | Leukomalacia, Periventricular - prevention & control | Brain Damage, Chronic - prevention & control | Apnea - epidemiology | Neurologic manifestations of general diseases | Evaluation | Complications and side effects | Apnea | Infants (Premature) | Erythrocytes | Causes of | Research | Blood transfusion | Hemorrhage | Blood transfusions | Babies | Hematology | Premature birth | Clinical trials
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10. Full Text Isolated Cystic Periventricular Leukomalacia Differs from Cystic Periventricular Leukomalacia with Intraventricular Hemorrhage in Prevalence, Risk Factors and Outcomes in Preterm Infants
by Wang, Lan-Wan and Lin, Yung-Chieh and Tu, Yi-Fang and Wang, Shan-Tair and Huang, Chao-Ching and Taiwan Premature Infant Dev Collab and Taiwan Premature Infant Developmental Collaborative Study Group and for the Taiwan Premature Infant Developmental Collaborative Study Group
Neonatology, ISSN 1661-7800, 12/2016, Volume 111, Issue 1, pp. 86 - 92
Background: Cystic periventricular leukomalacia (cPVL) is the most severe white matter injury and is often associated with intraventricular hemorrhage (IVH) in... 
Cystic periventricular leukomalacia | Intraventricular hemorrhage | Premature infants | Risk factor | VENTILATION | WHITE-MATTER DAMAGE | PREMATURE-INFANTS | Intraventricular | INJURY | PEDIATRICS | SEPSIS | BRAIN | hemorrhage | Severity of Illness Index | Brain - diagnostic imaging | Tertiary Care Centers | Humans | Risk Factors | Infant | Logistic Models | Male | Leukomalacia, Periventricular - complications | Leukomalacia, Periventricular - diagnostic imaging | Cerebral Hemorrhage - diagnostic imaging | Gestational Age | Birth Weight | Cerebral Hemorrhage - epidemiology | Infant, Premature | Taiwan - epidemiology | Ultrasonography | Female | Retrospective Studies | Odds Ratio | Cerebral Hemorrhage - complications | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Index Medicus
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11. Full Text Recurrent Postnatal Infections Are Associated With Progressive White Matter Injury in Premature Infants
by Glass, Hannah C and Bonifacio, Sonia L and Chau, Vann and Glidden, David and Poskitt, Kenneth and Barkovich, A. James and Ferriero, Donna M and Miller, Steven P
Pediatrics, ISSN 0031-4005, 08/2008, Volume 122, Issue 2, pp. 299 - 305
OBJECTIVE. Our objective was to identify clinical predictors of progressive white matter injury. METHODS. We evaluated 133 infants of < 34 weeks of gestation... 
Infection | Premature | Infant | Leukomalacia | Periventricular | MRI | infection | BRAIN-INJURY | PERIVENTRICULAR LEUKOMALACIA | infant | NEWBORNS | OVINE FETUS | premature | leukomalacia | ENDOTOXIN EXPOSURE | periventricular | EXTREMELY PRETERM INFANTS | PEDIATRICS | BIRTH | Recurrence | Confidence Intervals | Follow-Up Studies | Humans | Magnetic Resonance Imaging - methods | Male | Reference Values | Case-Control Studies | Bronchopulmonary Dysplasia - epidemiology | Intensive Care Units, Neonatal | Female | Child Development - physiology | Infant, Premature, Diseases - epidemiology | Odds Ratio | Infant, Newborn | Leukomalacia, Periventricular - epidemiology | Severity of Illness Index | Birth Injuries - epidemiology | Meningitis, Bacterial - diagnosis | Myelin Sheath - pathology | Comorbidity | Logistic Models | Birth Injuries - diagnosis | Gestational Age | Bronchopulmonary Dysplasia - diagnosis | Meningitis, Bacterial - epidemiology | Bacterial Infections - epidemiology | Bacterial Infections - diagnosis | Leukomalacia, Periventricular - diagnosis | Causality | Cohort Studies | Brain | Perinatal infection | Research | Infants (Premature) | Injuries | Risk factors | Babies | Pediatrics | Nuclear magnetic resonance--NMR | Premature birth | Brain damage | Infections
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12. Full Text Motor and cognitive outcome after specific early lesions of the brain - a systematic review
by Hielkema, Tjitske and Hadders-Algra, Mijna
Developmental Medicine and Child Neurology, ISSN 0012-1622, 03/2016, Volume 58, Issue S4, pp. 46 - 52
The aim of this systematic review was to study motor and cognitive outcome in infants with severe early brain lesions and to evaluate effects of side of the... 
DEVELOPMENTAL TRAJECTORIES | BIRTH-WEIGHT INFANTS | CRANIAL ULTRASOUND | RISK-FACTORS | ARTERIAL ISCHEMIC-STROKE | INTRAVENTRICULAR HEMORRHAGE | PERIVENTRICULAR LEUKOMALACIA | PEDIATRICS | PRETERM INFANTS | NEURODEVELOPMENTAL OUTCOMES | NEONATAL CEREBRAL INFARCTION | CLINICAL NEUROLOGY | Cerebral Palsy - etiology | Cerebral Palsy - epidemiology | Humans | Stroke - complications | Infant | Stroke - epidemiology | Leukomalacia, Periventricular - complications | Intellectual Disability - etiology | Infant, Premature, Diseases - epidemiology | Leukomalacia, Periventricular - epidemiology | Intellectual Disability - epidemiology
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13. Full Text Risk factors for preoperative periventricular leukomalacia in term neonates with hypoplastic left heart syndrome are patient related
by Goff, Donna A., MD, MS and Shera, David M., ScD and Tang, Stephen, BS and