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1. Full Text Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
by Lundblad, M and Andersson, M and Winkler, C and Kirik, D and Wierup, N and Cenci, M. A
The European journal of neuroscience, ISSN 0953-816X, 01/2002, Volume 15, Issue 1, pp. 120 - 132
movement disorders | preclinical | circling | turning | stereotypies | Turning | Stereotypies | Preclinical | Circling | Movement disorders | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Levodopa - pharmacology | Antiparkinson Agents - pharmacology | Dyskinesia, Drug-Induced - psychology | Stereotyped Behavior - drug effects | Motor Activity - drug effects | Rats | Bromocriptine - pharmacology | Rats, Sprague-Dawley | Rotation | Anti-Dyskinesia Agents - pharmacology | Gait - drug effects | Animals | Oxidopamine - pharmacology | Dyskinesia, Drug-Induced - drug therapy | Parkinson Disease, Secondary - psychology | Sympatholytics - pharmacology | Behavior, Animal - drug effects | Female | Parkinson Disease, Secondary - chemically induced | Index Medicus | Oxidopamine : pharmacology | Sympatholytics : pharmacology | Anti-Dyskinesia Agents : pharmacology | Basic Medicine | Parkinson Disease Secondary : chemically induced : psychology | Medical and Health Sciences | Rats Sprague-Dawley | Medicin och hälsovetenskap | Gait : drug effects | Bromocriptine : pharmacology | Dyskinesia Drug-Induced : drug therapy : psychology | Levodopa : pharmacology | Animal | Medicinska och farmaceutiska grundvetenskaper | Motor Activity : drug effects | Support Non-U.S. Gov't | Behavior Animal : drug effects | Antiparkinson Agents : pharmacology | Stereotyped Behavior : drug effects | Neurovetenskaper
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2. Full Text The pharmacology of L-DOPA-induced dyskinesia in Parkinson's disease
by Huot, Philippe and Johnston, Tom H and Koprich, James B and Fox, Susan H and Brotchie, Jonathan M
Pharmacological reviews, ISSN 0031-6997, Volume 65, Issue 1, pp. 171 - 222
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Dyskinesia, Drug-Induced - etiology | Synaptic Transmission - physiology | Dyskinesia, Drug-Induced - physiopathology | Humans | Parkinson Disease - drug therapy | Parkinson Disease - physiopathology | Antiparkinson Agents - adverse effects | Basal Ganglia - physiology | Dopamine Agents - adverse effects | Animals | Levodopa - adverse effects | Parkinson Disease - metabolism | Dyskinesia, Drug-Induced - metabolism | Index Medicus
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3. Full Text Vesicular Dopamine Release Elicits an Inhibitory Postsynaptic Current in Midbrain Dopamine Neurons
by Beckstead, Michael J and Grandy, David K and Wickman, Kevin and Williams, John T
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2004, Volume 42, Issue 6, pp. 939 - 946
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Sulpiride - pharmacology | G Protein-Coupled Inwardly-Rectifying Potassium Channels | Mesencephalon - cytology | Calcium - metabolism | Male | Dose-Response Relationship, Drug | Dopamine Agents - pharmacology | Neurons - physiology | Organophosphorus Compounds - pharmacology | Reserpine - pharmacology | Female | Tetrodotoxin - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Action Potentials - drug effects | Dopamine - metabolism | Levodopa - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Mice, Inbred C57BL | Potassium Channels, Inwardly Rectifying | Sodium Channel Blockers - pharmacology | Iontophoresis - methods | Calcium Channel Blockers - pharmacology | Receptors, Dopamine D2 - genetics | GABA Antagonists - pharmacology | Mice, Knockout | Potassium Channels - genetics | Cocaine - pharmacology | Animals | Analysis of Variance | Dopamine Antagonists - pharmacology | Receptors, Dopamine D3 | Adrenergic Uptake Inhibitors - pharmacology | Mice | In Vitro Techniques | Neurons - radiation effects | Dose-Response Relationship, Radiation | Neural Inhibition - drug effects | Dopamine | Neurons | Experiments | Variance analysis | Rodents | Parkinsons disease | Index Medicus
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4. Full Text Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial
by Ferreira, Joaquim J, Prof and Lees, Andrew, Prof and Rocha, José-Francisco, BSc and Poewe, Werner, Prof and Rascol, Olivier, Prof and Soares-da-Silva, Patrício, Prof and Bi-Park 1 investigators and Bi-Pk 1 Investigators
Lancet neurology, ISSN 1474-4422, 2016, Volume 15, Issue 2, pp. 154 - 165
Neurology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Oxadiazoles - administration & dosage | Antiparkinson Agents - pharmacology | Catechol O-Methyltransferase Inhibitors - administration & dosage | Nitriles - pharmacology | Outcome Assessment (Health Care) | Catechol O-Methyltransferase Inhibitors - pharmacology | Humans | Middle Aged | Male | Dyskinesia, Drug-Induced - prevention & control | Parkinson Disease - drug therapy | Nitriles - administration & dosage | Levodopa - administration & dosage | Oxadiazoles - pharmacology | Aged, 80 and over | Catechols - pharmacology | Adult | Female | Drug Therapy, Combination | Dyskinesia, Drug-Induced - etiology | Levodopa - pharmacology | Double-Blind Method | Europe | Antiparkinson Agents - adverse effects | Levodopa - adverse effects | Aged | Antiparkinson Agents - administration & dosage | Catechols - administration & dosage | Clinical trials | Medical colleges | Neurosciences | Catechin | Dopa | Transferases | Drug dosages | Parkinsons disease | Clinical medicine | Index Medicus
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5. Full Text Effect of opicapone and entacapone upon levodopa pharmacokinetics during three daily levodopa administrations
by Rocha, José-Francisco and Falcão, Amílcar and Santos, Ana and Pinto, Roberto and Lopes, Nelson and Nunes, Teresa and Wright, Lyndon C and Vaz-da-Silva, Manuel and Soares-da-Silva, Patrício
European journal of clinical pharmacology, ISSN 0031-6970, 9/2014, Volume 70, Issue 9, pp. 1059 - 1071
Biomedicine | Carbidopa | COMT inhibitors | Opicapone | Entacapone | Levodopa | Pharmacology/Toxicology | Pharmacokinetics | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Antiparkinson Agents - pharmacology | Nitriles - pharmacology | Area Under Curve | Catechol O-Methyltransferase Inhibitors - pharmacology | Humans | Middle Aged | Levodopa - pharmac