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Journal of Controlled Release, ISSN 0168-3659, 09/2015, Volume 213, pp. 57 - 68
Women urgently need a self-initiated, multipurpose prevention technology (MPT) that simultaneously reduces their risk of acquiring HIV-1, HSV-2, and HPV... 
Efficacy | Core–matrix design | Contraception | Multipurpose prevention technology | Microbicides | Intravaginal ring | Core-matrix design | CLINICAL-TRIAL | HUMAN-IMMUNODEFICIENCY-VIRUS | CHEMISTRY, MULTIDISCIPLINARY | VAGINAL RING | TENOFOVIR DISOPROXIL FUMARATE | IN-VITRO | TYPE-2 INFECTION | COMBINATION MICROBICIDE | PHARMACOLOGY & PHARMACY | REVERSE-TRANSCRIPTASE INFECTION | HUMAN-PAPILLOMAVIRUS INFECTION | PROTECTS MACAQUES | Contraceptive Agents, Female - pharmacology | HIV Infections - prevention & control | Drug Delivery Systems - instrumentation | Antiviral Agents - pharmacokinetics | Urea - pharmacokinetics | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Contraceptive Agents, Female - administration & dosage | Pyridines - pharmacokinetics | Administration, Intravaginal | Human papillomavirus 16 - drug effects | Macaca mulatta | Equipment Design | Herpes Genitalis - prevention & control | Levonorgestrel - pharmacokinetics | Carrageenan - pharmacology | Urea - analogs & derivatives | Zinc Acetate - administration & dosage | Contraceptive Agents, Female - pharmacokinetics | Female | Herpesvirus 2, Human - drug effects | Urea - administration & dosage | Cell Line | Antiviral Agents - pharmacology | Levonorgestrel - pharmacology | Pyridines - administration & dosage | HIV-1 - drug effects | Carrageenan - pharmacokinetics | Contraceptive Devices, Female - virology | Antiviral Agents - administration & dosage | Pregnancy | Animals | Levonorgestrel - administration & dosage | Papillomavirus Infections - prevention & control | Zinc Acetate - pharmacokinetics | Zinc Acetate - pharmacology | Pyridines - pharmacology | HeLa Cells | Urea - pharmacology | Carrageenan - administration & dosage | Prevention | Contraceptives | Carrageenin | Pregnant women | Elastomers | Liquefied natural gas | HIV (Viruses) | Warships | intravaginal ring | multipurpose prevention technology | core-matrix design | contraception | microbicides | efficacy
Journal Article
Journal Article
Contraception, ISSN 0010-7824, 2014, Volume 90, Issue 2, pp. 123 - 129
Abstract Objectives The potential effect of hormonal contraception on HIV-1 acquisition and transmission represents an important public health issue. Several... 
Obstetrics and Gynecology | HIV-1 | LNG | Progestins | AIDS | ETG | DMPA | Hormonal contraception | NET | LENTIVIRUS-INDUCED PROTECTION | DEPOT MEDROXYPROGESTERONE | FACTOR-KAPPA-B | OBSTETRICS & GYNECOLOGY | HORMONAL CONTRACEPTIVE USE | GLUCOCORTICOID-RECEPTOR | HIV ACQUISITION | INTRAUTERINE SYSTEM | INTRAMUSCULAR INJECTION | MOLECULAR-MECHANISMS | RHESUS MACAQUES | Contraceptive Agents, Female - adverse effects | Contraceptive Agents, Female - pharmacology | Progestins - metabolism | Desogestrel - adverse effects | Dendritic Cells - immunology | Humans | Progestins - adverse effects | Medroxyprogesterone Acetate - pharmacology | Delayed-Action Preparations - chemistry | Medroxyprogesterone Acetate - metabolism | Desogestrel - metabolism | Lymphocytes - immunology | Delayed-Action Preparations - pharmacology | Norethindrone - adverse effects | Toll-Like Receptors - antagonists & inhibitors | Contraceptive Agents, Female - antagonists & inhibitors | Medroxyprogesterone Acetate - adverse effects | Adult | Dendritic Cells - drug effects | Female | Contraceptive Agents, Female - metabolism | Toll-Like Receptors - metabolism | Dendritic Cells - metabolism | Immune Tolerance - drug effects | Lymphocytes - metabolism | Levonorgestrel - pharmacology | Cytokines - metabolism | Cells, Cultured | Progestins - pharmacology | Imidazoles - pharmacology | Lymphocytes - cytology | Toll-Like Receptors - agonists | Desogestrel - pharmacology | Delayed-Action Preparations - metabolism | HIV-1 - immunology | Progestins - antagonists & inhibitors | Delayed-Action Preparations - adverse effects | Levonorgestrel - adverse effects | Lymphocyte Activation - drug effects | Lymphocytes - drug effects | Norethindrone - pharmacology | Medroxyprogesterone Acetate - antagonists & inhibitors | Dendritic Cells - cytology | Oligodeoxyribonucleotides - pharmacology | Progestational hormones, Synthetic | Contraceptive drugs | Progestational hormones | T cells | Analysis | hormonal contraception | progestins
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0159332
Women need multipurpose prevention products (MPTs) that protect against sexually transmitted infections (STIs) and provide contraception. The Population... 
WOMEN | IN-VITRO | PHARMACOKINETICS | HIV ACQUISITION | MULTIDISCIPLINARY SCIENCES | PREVENTION | REVERSE-TRANSCRIPTASE INFECTION | PHARMACODYNAMICS | CONTRACEPTIVES | GEL | HPV | Contraceptive Agents, Female - pharmacology | Vagina - drug effects | Anti-Infective Agents - pharmacology | Reassortant Viruses - genetics | Reverse Transcriptase Inhibitors - pharmacology | Simian Immunodeficiency Virus - growth & development | Reassortant Viruses - drug effects | Macaca mulatta | HIV - drug effects | Simian Immunodeficiency Virus - genetics | Carrageenan - pharmacology | Urea - analogs & derivatives | Female | Mucous Membrane - drug effects | Levonorgestrel - pharmacology | Mucous Membrane - virology | Contraceptive Devices, Female | Treatment Outcome | HIV - growth & development | Reassortant Viruses - growth & development | Animals | Zinc Acetate - pharmacology | Vagina - virology | HIV - genetics | Pyridines - pharmacology | Simian Immunodeficiency Virus - drug effects | Drug Combinations | Urea - pharmacology | Women | Anti-infective agents | Care and treatment | HIV infection | Health aspects | Analysis | Health care | Sexually transmitted diseases--STD | RNA-directed DNA polymerase | Mucosa | Infections | Tissues | Prevention | Reproduction | Human papillomavirus | Acquired immune deficiency syndrome--AIDS | Compartments | Human immunodeficiency virus--HIV | Inhibition | Zinc acetate | Enzyme-linked immunosorbent assay | Reproductive systems | Computational fluid dynamics | Vagina | Contraception | Cervix | Zinc | Pregnancy | Studies | Carrageenan | Acetic acid | STD | Sexually transmitted diseases | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article