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PLoS pathogens, ISSN 1553-7374, 08/2018, Volume 14, Issue 8, pp. e1007264 - e1007264
Herpes Simplex Virus 1 (HSV1) is amongst the most clinically advanced oncolytic virus platforms. However, efficient and sustained viral replication within... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Catalytic Domain - drug effects | Humans | Cercopithecus aethiops | Eukaryotic Initiation Factor-4E - metabolism | Phosphoproteins - metabolism | Herpes Simplex - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Neoplasms - complications | Neoplasms - virology | Neoplasms - genetics | HEK293 Cells | Immediate-Early Proteins - deficiency | Gene Expression Regulation, Neoplastic - drug effects | Organisms, Genetically Modified | Eukaryotic Initiation Factor-4E - genetics | Vero Cells | Cells, Cultured | Signal Transduction - genetics | Phosphoproteins - genetics | Herpesvirus 1, Human - drug effects | Animals | Immediate-Early Proteins - genetics | TOR Serine-Threonine Kinases - chemistry | Herpes Simplex - pathology | Adaptor Proteins, Signal Transducing - genetics | Ubiquitin-Protein Ligases - deficiency | Herpes Simplex - complications | Herpesvirus 1, Human - genetics | Mice | Protein Kinase Inhibitors - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | Physiological aspects | Genetic aspects | Research | Genetic regulation | Herpes simplex virus | Cancer cells | TOR protein | Transplants & implants | Funding | Xenotransplantation | Herpes simplex | Viruses | Genomes | mRNA | Infections | Biochemistry | Kinases | Proteins | Immunology | Repressors | Transformed cells | Immunotherapy | Xenografts | Oncolysis | Inhibition | Supervision | Medical research | Protein biosynthesis | Rapamycin | Pharmacology | Children & youth | Infectious diseases | Inhibitors | Protein synthesis | Herpes viruses | Replication | Initiation factor eIF-4E | Tumors | Cancer | Index Medicus | TOR Serine-Threonine Kinases/antagonists & inhibitiors | Herpes Simplex/genetics | Herpes Simplex/pathology | Neoplasms/pathology | Eukaryotic Initiation Factor-4E/genetics | Ubiquitin-Protein Ligases/deficiency | Immediate-Early Proteins/genetics | Neoplasms/genetics | Herpes Simplex/complications | Life Sciences | Eukaryotic Initiation Factor-4E/metabolism | Neoplasms/complications | Herpesvirus 1, Human/genetics | Catalytic Domain/drug effects | Signal Transduction/genetics | Adaptator Proteins, Signal Transducing/genetics | Gene Expression Regulation, Neoplastic/drug effects | Phosphoproteins/genetics | Adaptator Proteins, Signal Transducing/metabolism | Immediate-Early Proteins/deficiency | Phosphoproteins/metabolims | TOR Serine-Threonine Kinases/chemistry | Protein Kinase Inhibitors/pharmacology | Herpesvirus 1, Human/drug effects | Ubiquitin-Protein Ligases/genetics | Neoplasms/virology
Journal Article
Nature communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 5110 - 13
Non-small cell lung carcinoma (NSCLC) is leading cause of cancer-related deaths in the world. The Tumor Suppressor Candidate 3 (TUSC3) at chromosome 8p22 known... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Endoribonucleases - genetics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | MicroRNAs - metabolism | Activating Transcription Factor 6 - genetics | Tumor Suppressor Protein p53 - genetics | In Situ Hybridization | Tumor Suppressor Proteins - genetics | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - physiology | Gene Expression Regulation, Neoplastic - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Proliferation - genetics | Tumor Suppressor Proteins - metabolism | Endoribonucleases - metabolism | Unfolded Protein Response - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Endoplasmic Reticulum-Associated Degradation - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Cell Proliferation - physiology | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Xenograft Model Antitumor Assays | Activating Transcription Factor 6 - metabolism | Animals | Endoplasmic Reticulum-Associated Degradation - physiology | Cell Line, Tumor | Signal Transduction - physiology | Mice | Ubiquitin-Protein Ligases - genetics | Unfolded Protein Response - physiology | Small cell lung carcinoma | p53 Protein | Lung cancer | Non-small cell lung carcinoma | Lung carcinoma | Metastasis | Substrates | Metastases | Proteins | Protein folding | Chromosome 8 | Tumor suppressor genes | miRNA | Solid tumors | Tumors | Cancer | Index Medicus
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 12/2013, Volume 31, Issue 34, pp. 4333 - 4342
Journal Article
Nature (London), ISSN 1476-4687, 12/2013, Volume 506, Issue 7488, pp. 371 - 375
Cervical cancer is responsible for 10-15% of cancer-related deaths in women worldwide(1,2). The aetiological role of infection with high-risk human papilloma... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | F-Box-WD Repeat-Containing Protein 7 | Receptor, ErbB-2 - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - virology | Genomics | Humans | E1A-Associated p300 Protein - genetics | Core Binding Factor beta Subunit - genetics | Case-Control Studies | Papillomaviridae - genetics | Tumor Suppressor Protein p53 - genetics | DNA Mutational Analysis | Mitogen-Activated Protein Kinase 1 - genetics | Cell Cycle Proteins - genetics | Female | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Papillomaviridae - physiology | HLA-B Antigens - genetics | Gene Expression Regulation, Neoplastic - genetics | Proto-Oncogene Proteins c-ets | Virus Integration - genetics | Proto-Oncogene Proteins - genetics | DNA Copy Number Variations - genetics | Transcriptome - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Uterine Cervical Neoplasms - genetics | Adenocarcinoma - virology | Genome, Human - genetics | Papillomavirus Infections - genetics | Exome - genetics | Uterine Cervical Neoplasms - virology | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Prevention | Gene mutations | Oncology, Experimental | Exome sequencing | Genetic aspects | Research | Cervical cancer | Cancer | Human papillomavirus | Mutation | Index Medicus
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 11/2012, Volume 143, Issue 5, pp. 1244 - 1252.e12
...) infection in genome-wide association (GWA) studies. Only a fraction of patients with chronic HCV infection develop liver fibrosis, a process that might also be affected by genetic factors... 
Gastroenterology and Hepatology | Cirrhosis | Genetic Analysis | Liver Disease | Risk Factors | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Humans | Hepatitis C, Chronic - virology | Apoptosis - genetics | Male | Hepatitis C, Chronic - complications | Young Adult | c-Mer Tyrosine Kinase | Adult | Female | Eye Proteins - genetics | Liver Cirrhosis - genetics | Genome-Wide Association Study | Membrane Proteins - genetics | Proportional Hazards Models | Genotype | Logistic Models | Proto-Oncogene Proteins - genetics | Disease Progression | Phenotype | Liver Cirrhosis - virology | Receptor Protein-Tyrosine Kinases - genetics | Polymorphism, Single Nucleotide | Ubiquitin-Protein Ligases - genetics | Hepacivirus | Lipase - genetics | Antiviral agents | Medical research | Medical colleges | Liver | Genomics | Immunodeficiency | Development and progression | Genomes | HIV (Viruses) | Risk factors | Analysis | Fibrosis | Medical genetics | Medicine, Experimental | Hepatitis C virus | Hepatitis C | Health aspects | Liver diseases | Genetic research | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Genetics | Hépatology and Gastroenterology | Infectious diseases | Human genetics | risk factors | genetic analysis | liver disease | cirrhosis
Journal Article
Journal of dental research, ISSN 1544-0591, 06/2012, Volume 91, Issue 7_suppl, pp. S21 - S28
.... To date, there is limited evidence on host genetic risk loci associated with periodontal pathogen colonization... 
infection | genetics | bacteria | dentistry | genome-wide association studies | chronic periodontitis | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Humans | Middle Aged | Periodontium - microbiology | Campylobacter rectus - classification | Male | Prevotella nigrescens - classification | Fusobacterium nucleatum - genetics | Prevotella intermedia - genetics | Interleukins - genetics | Metagenome - genetics | Chronic Periodontitis - microbiology | Trans-Activators - genetics | Treponema denticola - classification | Female | Bacteroides - classification | Porphyromonas gingivalis - genetics | Vesicle-Associated Membrane Protein 3 - genetics | Aggregatibacter actinomycetemcomitans - classification | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Nucleic Acid Hybridization | Interleukin-33 | Fusobacterium nucleatum - classification | Prevotella intermedia - classification | Potassium Channels, Tandem Pore Domain - genetics | Bacterial Load | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Prevotella nigrescens - genetics | Bacteroides - genetics | Campylobacter rectus - genetics | DNA, Bacterial - genetics | Treponema denticola - genetics | Aggregatibacter actinomycetemcomitans - genetics | Zinc Fingers - genetics | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Core Binding Factor Alpha 1 Subunit - genetics | Calcium-Binding Proteins - genetics | Porphyromonas gingivalis - classification | Index Medicus | Dentistry | Clinical Trials and Human Investigations
Journal Article
Chromosome research, ISSN 1573-6849, 05/2016, Volume 24, Issue 3, pp. 355 - 378
Journal Article