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Current Medicinal Chemistry, ISSN 0929-8673, 12/2013, Volume 20, Issue 37, pp. 4784 - 4805
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2017, Volume 27, Issue 2, pp. 176 - 179
(−)-Cubebin (CUB), isolated from seeds of , was used as starting material to obtain the derivatives (−)-hinokinin (HK) and (−)-O-benzyl cubebin (OBZ). Using... 
Anti-inflammatory activity | (−)-Hinokinin | Piper cubeba | (−)-Cubebin | (−)-O-benzylcubebin | CHEMISTRY, MEDICINAL | APPROXIMATION | (-)-Cubebin | LEAVES | CHEMISTRY, ORGANIC | (-)-Hinokinin | SWISS-MODEL | DENSITY | ZANTHOXYLUM-NARANJILLO | (-)-0-benzylcubebin | LIGNANS | ELECTROSTATICS | Rats, Wistar | Furans - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Benzodioxoles - administration & dosage | Cyclooxygenase 2 Inhibitors - chemistry | Dioxoles - chemical synthesis | Lignans - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Cyproheptadine - pharmacology | Polysorbates - pharmacology | Dextrans - pharmacology | Dioxoles - administration & dosage | Furans - chemistry | Computer Simulation | Dioxoles - pharmacology | 4-Butyrolactone - chemistry | Benzodioxoles - chemistry | Lignans - chemical synthesis | Rutaceae - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Benzodioxoles - chemical synthesis | Cyclooxygenase 2 Inhibitors - chemical synthesis | Dinoprostone - pharmacology | Catalytic Domain | Cyclooxygenase 2 Inhibitors - pharmacology | Lignans - chemistry | Cyclooxygenase 2 - chemistry | Cyclooxygenase 2 Inhibitors - administration & dosage | 4-Butyrolactone - pharmacology | 4-Butyrolactone - chemical synthesis | Dioxoles - chemistry | Indomethacin - pharmacology | Lignans - isolation & purification | Lignans - administration & dosage | Animals | 4-Butyrolactone - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Ligands | Mice | Molecular Docking Simulation | 4-Butyrolactone - analogs & derivatives | Edema - chemically induced | Furans - chemical synthesis | Benzodioxoles - pharmacology | Furans - administration & dosage
Journal Article
Medicinal Research Reviews, ISSN 0198-6325, 09/2008, Volume 28, Issue 5, pp. 746 - 772
Medicinal plants have been traditionally used for treating liver diseases since centuries. Several leads from plant sources have been found as potential... 
phyllanthin | picroside | silymarin | neoandrographolide | kutkoside | hepatoprotective | glycyrrhizin | andrographolide | curcumin | hypophyllanthin | Glycyrrhizin | Hepatoprotective | Kutkoside | Silymarin | Phyllanthin | Neoandrographolide | Curcumin | Andrographolide | Hypophyllanthin | Picroside | CLEOME-VISCOSA SEEDS | ANDROGRAPHIS-PANICULATA NEES | CHEMISTRY, MEDICINAL | RAT HEPATOCYTES | INDUCED HEPATIC DAMAGE | neoandrogapholide | INDUCED LIVER-INJURY | CYTOCHROME-P450 2E1 EXPRESSION | PHYLLANTHUS-AMARUS | CURCUMA-LONGA | PHARMACOLOGY & PHARMACY | CARBON-TETRACHLORIDE | INDUCED HEPATOTOXICITY | Silymarin - toxicity | Plant Extracts - toxicity | Diterpenes - toxicity | Plant Extracts - pharmacology | Humans | Protective Agents - chemistry | Curcumin - metabolism | Silymarin - chemistry | Lignans - pharmacology | Plant Extracts - metabolism | Glycyrrhizic Acid - pharmacology | Liver - drug effects | Glucosides - chemistry | Cinnamates - chemistry | Phytotherapy | Diterpenes - pharmacology | Glucosides - toxicity | Liver - metabolism | Curcumin - pharmacology | Lignans - metabolism | Plants | Cinnamates - pharmacology | Glucosides - metabolism | Tetrahydronaphthalenes - metabolism | Tetrahydronaphthalenes - pharmacology | Liver Diseases - drug therapy | Glycyrrhizic Acid - toxicity | Plant Extracts - therapeutic use | Curcumin - chemistry | Tetrahydronaphthalenes - toxicity | Protective Agents - metabolism | Protective Agents - therapeutic use | Lignans - toxicity | Protective Agents - pharmacology | Cinnamates - metabolism | Cinnamates - toxicity | Silymarin - metabolism | Silymarin - pharmacology | Diterpenes - metabolism | Diterpenes - chemistry | Glucosides - pharmacology | Cytokines - metabolism | Lignans - chemistry | Glycyrrhizic Acid - chemistry | Glycyrrhizic Acid - metabolism | Animals | Curcumin - toxicity | Tetrahydronaphthalenes - chemistry | Liver Diseases - metabolism | Protective Agents - toxicity
Journal Article
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2004, Volume 500, Issue 1, pp. 221 - 230
Natural products have been used as medicinal agents for many years. In addition, these compounds have also served as the starting points for semisynthetic... 
Natural product | s-(−)-3- n-butylphthalide | Huperzine A | Ginkgo biloba extract | (−)-Clausenamide | (-)-Clausenamide | s-(-)-3-n-butylphthalide | INDUCED OXIDATIVE INJURY | natural product | huperzine A | (-)-clausenamide | RAT CORTICAL-NEURONS | FOCAL CEREBRAL-ISCHEMIA | WILFORDII HOOK-F | HUPERZINE-A | ATTENUATES COGNITIVE DEFICITS | GINKGO-BILOBA CONSTITUENTS | PHARMACOLOGY & PHARMACY | POTENTIAL THERAPEUTIC AGENT | OXIDE-INDUCED NEUROTOXICITY | GROWTH-FACTOR EXPRESSION | Humans | Cholinesterase Inhibitors - chemistry | Drugs, Chinese Herbal - pharmacology | Benzofurans - pharmacology | Lignans - pharmacology | Benzofurans - chemistry | Alkaloids | Phenanthrenes - chemistry | Neuroprotective Agents - pharmacology | Berberine - analogs & derivatives | China | Lactams - pharmacology | Rutaceae - chemistry | Dopamine Antagonists - chemistry | Immunosuppressive Agents - pharmacology | Diterpenes - chemistry | Berberine - chemistry | Diterpenes - pharmacology | Dopamine Agonists - pharmacology | Epoxy Compounds | Neuroprotective Agents - chemistry | Sesquiterpenes - chemistry | Lignans - chemistry | Ginkgo biloba - chemistry | Berberine - pharmacology | Phenanthrenes - pharmacology | Animals | Cholinesterase Inhibitors - pharmacology | Dopamine Antagonists - pharmacology | Sesquiterpenes - pharmacology | Dopamine Agonists - chemistry | Immunosuppressive Agents - chemistry | Lactams - chemistry | Caprolactam
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2010, Volume 30, Issue 4, pp. 749 - 757
OBJECTIVE—Animal and clinical studies have suggested that polyphenols in fruits, red wine, and tea may delay the development of atherosclerosis through their... 
Endothelial dysfunction | Soluble P-selectin | Oxidative stress | Polyphenol | Inflammation | Endothelin-1 | polyphenol | endothelial dysfunction | soluble P-selectin | inflammation | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | BLACK TEA CONSUMPTION | SMOOTH-MUSCLE-CELLS | HEME OXYGENASE-1 | RED WINE | endothelin-1 | HEMATOLOGY | E-DEFICIENT MICE | NF-KAPPA-B | oxidative stress | CORONARY-ARTERY-DISEASE | Inflammation - pathology | Heme Oxygenase-1 - metabolism | Apolipoproteins E - deficiency | Cholesterol - blood | Endothelium, Vascular - drug effects | Male | Aorta - metabolism | F2-Isoprostanes - metabolism | Lignans - pharmacology | Aortic Diseases - metabolism | Inflammation - metabolism | Leukotriene B4 - metabolism | Aortic Diseases - prevention & control | Dioxoles - pharmacology | Polyphenols | Anti-Inflammatory Agents - administration & dosage | Disease Models, Animal | Phenols - pharmacology | Biomarkers - metabolism | Atherosclerosis - pathology | Anti-Inflammatory Agents - pharmacology | Atherosclerosis - physiopathology | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Diet | Endothelium, Vascular - metabolism | Inflammation - prevention & control | Mice | Oxidative Stress - drug effects | Biflavonoids - pharmacology | Chlorogenic Acid - pharmacology | Nitrates - urine | Superoxides - metabolism | Flavonoids - administration & dosage | Flavonoids - pharmacology | Membrane Proteins - metabolism | Aorta - physiopathology | Nitric Oxide Synthase Type III - metabolism | Catechin - pharmacology | Fatty Acids - metabolism | Nitrites - urine | Aorta - drug effects | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Aortic Diseases - physiopathology | Animals | Quercetin - pharmacology | Apolipoproteins E - genetics | Endothelin-1 - urine | P-Selectin - blood | Phenols - administration & dosage | Nitric Oxide - metabolism | Atherosclerosis - prevention & control | Inflammation - physiopathology
Journal Article
Best Practice & Research Clinical Endocrinology & Metabolism, ISSN 1521-690X, 2006, Volume 20, Issue 1, pp. 45 - 61
Journal Article