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1. Full Text Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism
by Evans, Simon J and Ringrose, Rachel N and Harrington, Gloria J and Mancuso, Peter and Burant, Charles F and McInnis, Melvin G
Journal of Psychiatric Research, ISSN 0022-3956, 2014, Volume 57, Issue 1, pp. 58 - 64
Abstract Polyunsaturated fatty acids (PUFA) profiles associate with risk for mood disorders. This poses the hypothesis of metabolic differences between... 
Psychiatry | Atypical antipsychotics | Omega-3 | Hydroperoxy octadecadienoic acid | Eicosadienoic acid | Omega-6 | ANTIPSYCHOTICS | PSYCHIATRY | INFLAMMATION | DISEASE | DISORDER | ADULTS | EXPRESSION | Linoleic Acid - blood | Bipolar Disorder - metabolism | Linoleic Acid - administration & dosage | Humans | Middle Aged | Arachidonic Acid - blood | Male | Eicosapentaenoic Acid - administration & dosage | Arachidonic Acid - administration & dosage | Dietary Fats - administration & dosage | Adult | Female | Fatty Acids, Omega-3 - administration & dosage | Selenium - blood | Risk Factors | Docosahexaenoic Acids - administration & dosage | Bipolar Disorder - blood | Eicosapentaenoic Acid - blood | Fatty Acids, Unsaturated - blood | Regression Analysis | Docosahexaenoic Acids - blood | Fatty Acids, Omega-3 - blood | Selenium - administration & dosage | Diet Surveys - statistics & numerical data | Fatty Acids, Unsaturated - administration & dosage | Unsaturated fatty acids | Linoleic acids | Analysis | Food habits | Dietary supplements | Physiological aspects | Electronic design automation | Bipolar disorder | Health aspects | Saturated fatty acids | Omega-3 fatty acids | eicosadienoic acid | omega-6 | omega-3 | hydroperoxy octadecadienoic acid | atypical antipsychotics
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2. Full Text Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice
by Marques, Tatiana M and Wall, Rebecca and O'Sullivan, Orla and Fitzgerald, Gerald F and Shanahan, Fergus and Quigley, Eamonn M and Cotter, Paul D and Cryan, John F and Dinan, Timothy G and Ross, R. Paul and Stanton, Catherine
British Journal of Nutrition, ISSN 0007-1145, 03/2015, Volume 113, Issue 5, pp. 728 - 738
The main aim of the present study was to investigate the effects of dietary trans-10, cis-12-conjugated linoleic acid (t10c12-CLA) on intestinal microbiota... 
Intestinal microbiota | trans-10, cis-12-Conjugated linoleic acid | Lipid metabolism | cis-12-Conjugated linoleic acid | LIPID-METABOLISM | ATHEROSCLEROSIS | GERM-FREE MICE | MECHANISMS | GUT MICROBIOTA | BODY-COMPOSITION | LIVER-DISEASE | OBESITY | NUTRITION & DIETETICS | trans-10 | INSULIN-RESISTANCE | ADIPOSE-TISSUE | Non-alcoholic Fatty Liver Disease - pathology | Intestinal Mucosa - metabolism | Liver - pathology | Non-alcoholic Fatty Liver Disease - etiology | Anti-Obesity Agents - adverse effects | Male | Intestines - metabolism | Fatty Acids, Volatile - metabolism | Molecular Typing | Microbiota | Adiposity | Gastrointestinal Contents - chemistry | Dietary Supplements - adverse effects | Gastrointestinal Contents - microbiology | Bacteroidetes - isolation & purification | Biomarkers - metabolism | Cecum | Liver - metabolism | Mice, Inbred C57BL | Non-alcoholic Fatty Liver Disease - microbiology | Biomarkers - analysis | Organ Size | Non-alcoholic Fatty Liver Disease - metabolism | Biomarkers - blood | Intestinal Mucosa - microbiology | Bacteroidetes - classification | Fatty Acids, Volatile - analysis | Animals | Intestines - microbiology | Bacteroidetes - metabolism | Bacteroidetes - growth & development | Intra-Abdominal Fat - pathology | Linoleic Acids, Conjugated - adverse effects | Lipids | Microbiology | Metabolism | Digestive system | Fatty acids | Rodents | Näringslära | Medical and Health Sciences | Medicin och hälsovetenskap | Trans-10 | Hälsovetenskaper | Nutrition and Dietetics | Health Sciences
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3. Full Text Dietary oils and FADS1-FADS2 genetic variants modulate [ 13C]α-linolenic acid metabolism and plasma fatty acid composition
by Gillingham, Leah G and Harding, Scott V and Rideout, Todd C and Yurkova, Natalia and Cunnane, Stephen C and Eck, Peter K and Jones, Peter J.H
American Journal of Clinical Nutrition, ISSN 0002-9165, 01/2013, Volume 97, Issue 1, pp. 195 - 207
Background: Desaturation of dietary alpha-linolenic acid (ALA) to omega-3 (n-3) long-chain fatty acids (FAs) is mediated through FA desaturases (FADS1-FADS2)... 
BETA-OXIDATION | NUTRITION & DIETETICS | CONVERSION | DOCOSAHEXAENOIC ACID | IN-VIVO | CARDIOVASCULAR-DISEASE | NONFATAL MYOCARDIAL-INFARCTION | DESATURASE ACTIVITY | CORONARY-HEART-DISEASE | CLUSTER | ALPHA-LINOLENIC ACID | Linoleic Acid - blood | Single-Blind Method | Linoleic Acid - administration & dosage | Fatty Acids, Monounsaturated - administration & dosage | Humans | Middle Aged | Arachidonic Acid - blood | Dietary Fats, Unsaturated - blood | Male | Eicosapentaenoic Acid - administration & dosage | Arachidonic Acid - administration & dosage | Young Adult | Oleic Acid - blood | Lipids - blood | Adult | Fatty Acids, Monounsaturated - blood | Female | Fatty Acids - blood | alpha-Linolenic Acid - administration & dosage | alpha-Linolenic Acid - blood | Fatty Acid Desaturases - genetics | Oleic Acid - administration & dosage | Lipid Metabolism | Biomarkers - blood | Canola Oil | Docosahexaenoic Acids - administration & dosage | Cross-Over Studies | Eicosapentaenoic Acid - blood | Docosahexaenoic Acids - blood | Diet | Adolescent | Alleles | Dietary Fats, Unsaturated - administration & dosage | Aged | Polymorphism, Single Nucleotide | Linseed Oil - administration & dosage
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4. Full Text Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study
by Snowden, Stuart G and Ebshiana, Amera A and Hye, Abdul and An, Yang and Pletnikova, Olga and O’Brien, Richard and Troncoso, John and Legido-Quigley, Cristina and Thambisetty, Madhav
PLoS Medicine, ISSN 1549-1277, 03/2017, Volume 14, Issue 3, p. e1002266
Background The metabolic basis of Alzheimer disease (AD) pathology and expression of AD symptoms is poorly understood. Omega-3 and -6 fatty acids have... 
TRIAL | MEDICINE, GENERAL & INTERNAL | PLASMA | MEDITERRANEAN DIET | OLIVE OIL | MOUSE MODEL | RISK | AGING BLSA | LIPID MEDIATORS | TAU PATHOLOGY | IMPAIRMENT | Alzheimer Disease - physiopathology | Humans | Middle Aged | Metabolome | Male | Cognition | Cognitive Dysfunction - physiopathology | Brain - metabolism | Baltimore | Aged, 80 and over | Female | Aged | Fatty Acids - metabolism | Longitudinal Studies | Psychological aspects | Fatty acid metabolism | Physiological aspects | Development and progression | Genetic aspects | Research | Cognition disorders | Alzheimer's disease | Essential fatty acids | Risk factors | Heart | Cerebellum | Brain | Transformation | Memory | Psychology | Cognitive ability | Nervous system | Biochemistry | Arachidonic acid | Blood | Proteins | Alterations | Archives & records | Autopsy | Arachidonate 5-lipoxygenase | Aging | Biocompatibility | Archives | Cadmium | Phospholipase A2 | Cytokines | Neurodegenerative diseases | Mortality | Metabolism | Assessments | Fatty acids | Studies | Pathology | Neurology | Diet | β-Amyloid | Death | Mice | Fats | Hippocampus | Dementia | Surgical implants | Neurosciences | Laboratories | Neuropathology | Circuits | Polyunsaturated fatty acids | Lipids | Risk | Cytochemistry | Prostaglandins | Immunology | Metabolites | Cerebral blood flow | Rodents | Dementia disorders | Heart diseases | Pharmaceutical sciences | Deposition | Aspirin | Autopsies | Nutrition | Health risks | Abundance | Inflammation | Coronary artery disease | Biological activity | Blood flow | Medicine | Alzheimers disease | Histochemistry | Pharmaceuticals | Polymorphism | Fish oils
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5. Full Text Conjugated linoleic acid metabolism
by Banni, Sebastiano
Current Opinion in Lipidology, ISSN 0957-9672, 2002, Volume 13, Issue 3, pp. 261 - 266
Conjugated linoleic acid (CLA) is a naturally occurring fatty acid that is produced by a bio-hydrogenation process in the rumen, and thus is present in dairy... 
RAT-LIVER | CANCER RISK | CLA ISOMERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-3 FATTY-ACIDS | BODY-COMPOSITION | PERFORMANCE LIQUID-CHROMATOGRAPHY | SKELETAL-MUSCLE | ENDOCRINOLOGY & METABOLISM | PERIPHERAL VASCULAR DISEASE | MICE | GLUCOSE-TOLERANCE | MAMMARY-GLAND | Animals | Linoleic Acid - metabolism | Fatty Acids - metabolism | Isomerism | Humans | Peroxisomes - metabolism
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6. Full Text Fatty acid metabolism in cystic fibrosis
by Strandvik, Birgitta and Institute of Clinical Sciences, Section for the Health of Women and Children and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa and Sahlgrenska Academy
Prostaglandins, Leukotrienes and Essential Fatty Acids, ISSN 0952-3278, 2010, Volume 83, Issue 3, pp. 121 - 129
Abstract Despite identification twenty years ago of the gene responsible for cystic fibrosis transmembrane conductance regulator (CFTR), the protein defective... 
Endocrinology & Metabolism | Advanced Basic Science | Ceramides | Arachidonic acid | Docosahexaenoic acid | Annexin | Cholesterol | OXIDATIVE STRESS | BONE-MINERAL DENSITY | LINOLEIC-ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | ARACHIDONIC-ACID | CELL BIOLOGY | PHOSPHOLIPASE-A2 ACTIVITY | EPITHELIAL-CELLS | PSEUDOMONAS-AERUGINOSA | ENDOCRINOLOGY & METABOLISM | ANNEXIN-V | CERAMIDE DEFICIENCY | Arachidonic Acid - metabolism | Animals | Ceramides - metabolism | Annexins - metabolism | Cystic Fibrosis - metabolism | Linoleic Acid - metabolism | Models, Biological | Humans | Lipid Metabolism | Fatty Acids - metabolism | Docosahexaenoic Acids - metabolism | Cell research | Monounsaturated fatty acids | Physiological aspects | Lipids | Cystic fibrosis | Annexins | Omega-3 fatty acids | Immunologi inom det medicinska området | Övrig annan samhällsvetenskap | Other Social Sciences not elsewhere specified | Immunology in the medical area
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7. Full Text Fatty acid metabolism in lambs fed citrus pulp
by Lanza, M and Scerra, M and Bognanno, M and Buccioni, A and Cilione, C and Biondi, L and Priolo, A and Luciano, G
Journal of Animal Science, ISSN 0021-8812, 06/2015, Volume 93, Issue 6, pp. 3179 - 3188
In the present study, we have hypothesized that replacing barley with high proportions of dried citrus pulp in a concentrate-based diet for lambs could... 
Metabolism | Fatty acids | Lamb | Citrus pulp | Meat quality | meat quality | citrus pulp | BACTERIA | AGRICULTURE, DAIRY & ANIMAL SCIENCE | fatty acids | QUEBRACHO TANNINS | LINOLEIC-ACID | BY-PRODUCTS | MEAT | RUMINAL BIOHYDROGENATION | PROFILE | lamb | RUMEN | PLANTS | metabolism | MILK | Citrus - metabolism | Animals | Animal Feed - analysis | Animal Nutritional Physiological Phenomena | Muscle, Skeletal - chemistry | Citrus - chemistry | Lipid Metabolism | Sheep - metabolism | Linoleic Acids, Conjugated - metabolism | Body Fluids | Fatty Acids - metabolism | Diet - veterinary | Research | Fatty acid metabolism | Citrus juices | Lambs | Health aspects
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8. Full Text Conjugated linoleic acids influence fatty acid metabolism in ovine ruminal epithelial cells
by Masur, F and Benesch, F and Pfannkuche, H and Fuhrmann, H and Gäbel, G
Journal of Dairy Science, ISSN 0022-0302, 04/2016, Volume 99, Issue 4, pp. 3081 - 3095
Conjugated linoleic acids (CLA), particularly -9, -11 (c9t11) and -10, -12 (t10c12), are used as feed additives to adapt to constantly increasing demands on... 
conjugated linoleic acid | monocarboxylate transporter | peroxisome proliferator-activated receptor | stearoyl-CoA desaturase | rumen epithelium | Conjugated linoleic acid | Stearoyl-CoA desaturase | Rumen epithelium | Peroxisome proliferator-activated receptor | Monocarboxylate transporter | PPAR-ALPHA | AGRICULTURE, DAIRY & ANIMAL SCIENCE | LIPID-METABOLISM | MESSENGER-RNA EXPRESSION | 1 GENE-EXPRESSION | FOOD SCIENCE & TECHNOLOGY | COENZYME-A DESATURASE | REAL-TIME PCR | TRANS-10,CIS-12 ISOMER | SMOOTH-MUSCLE-CELLS | VASCULAR ENDOTHELIAL-CELLS | STEAROYL-COENZYME | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Cells, Cultured | Lactation - drug effects | Oleic Acids | RNA, Messenger - analysis | RNA, Messenger - metabolism | Stearoyl-CoA Desaturase - genetics | Linoleic Acids, Conjugated - pharmacology | PPAR gamma - physiology | Animals | Rumen - metabolism | PPAR alpha - physiology | Female | Sheep - metabolism | Monocarboxylic Acid Transporters - genetics | Fatty Acids - metabolism
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9. Full Text Consumption of aquaculture waste affects the fatty acid metabolism of a benthic invertebrate
by White, Camille A and Bannister, Raymond J and Dworjanyn, Symon A and Husa, Vivian and Nichols, Peter D and Kutti, Tina and Dempster, Tim
Science of the Total Environment, ISSN 0048-9697, 05/2017, Volume 586, pp. 1170 - 1181
Trophic subsidies can drive widespread ecological change, thus knowledge of how keystone species respond to subsidies is important. Aquaculture of large... 
Trophic subsidy | Echinus acutus | Fatty acid | Dietary tracer | Aquaculture waste | Linoleic acid | ECHINUS-ESCULENTUS | ORGANIC ENRICHMENT | CAGE FISH FARMS | TROPHIC INTERACTIONS | PSAMMECHINUS-MILIARIS | MYTILUS-GALLOPROVINCIALIS LMK | SEA-URCHIN | WILD FISH | ENVIRONMENTAL SCIENCES | URCHIN STRONGYLOCENTROTUS-DROEBACHIENSIS | DIETARY LIPIDS | Arachidonic Acid - metabolism | Animals | Norway | Salmon | Sea Urchins - metabolism | Eicosapentaenoic Acid - metabolism | Fatty Acids - metabolism | Animal Feed | Aquaculture | Animal experimentation | Monounsaturated fatty acids | Fishes | Aquaculture industry | Physiological aspects | Mariculture | Consumption data | Arachidonic acid | Seafood industry | Energy management systems | Omega-3 fatty acids
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10. Full Text Fatty acid metabolism in human preimplantation embryos
by Haggarty, P and Wood, M and Ferguson, E and Hoad, G and Srikantharajah, A and Milne, E and Hamilton, M and Bhattacharya, S
Human Reproduction, ISSN 0268-1161, 03/2006, Volume 21, Issue 3, pp. 766 - 773
BACKGROUND: Little is known of fatty acid metabolism in human embryos. This information would be useful in developing metabolic tests of embryo quality and... 
IVF | Embryo | Fatty acids | Stem cells | Linoleic acid | stem cells | PROTEIN-KINASE-C | TURNOVER | fatty acids | linoleic acid | embryo | BOVINE OOCYTES | OBSTETRICS & GYNECOLOGY | BODY-FAT | REPRODUCTIVE BIOLOGY | IMMATURE | IN-VITRO FERTILIZATION | Pregnancy | Gas Chromatography-Mass Spectrometry | Biological Transport | Fatty Acids - isolation & purification | Humans | Blastocyst - metabolism | Carbon Isotopes | Isotope Labeling | Female | Morula - metabolism | Fatty Acids - metabolism
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11. Full Text Dietary Linoleic Acid Lowering Reduces Lipopolysaccharide-Induced Increase in Brain Arachidonic Acid Metabolism
by Taha, Ameer Y and Blanchard, Helene C and Cheon, Yewon and Ramadan, Epolia and Chen, Mei and Chang, Lisa and Rapoport, Stanley I
Molecular Neurobiology, ISSN 0893-7648, 8/2017, Volume 54, Issue 6, pp. 4303 - 4315
Linoleic acid (LA, 18:2n-6) is a precursor to arachidonic acid (AA, 20:4n-6), which can be converted by brain lipoxygenase and cyclooxygenase (COX) enzymes... 
Neurosciences | Lowering | Deficiency | Neurobiology | Bacterial lipopolysaccharide | Neuroinflammation | Omega-6 (n-6) | Cell Biology | Polyunsaturated fatty acids (PUFAs) | Neurology | Biomedicine | Docosahexaenoic acid (DHA) | Linoleic acid (LA) | Ventricle | Omega-3 (n-3) | ADULT RATS | ALZHEIMERS-DISEASE | FATTY-ACIDS | N-6 PUFA DEPRIVATION | NEUROSCIENCES | THIN-LAYER-CHROMATOGRAPHY | DOCOSAHEXAENOIC ACID | ACYL-COA CONCENTRATIONS | IN-VIVO | NEURONAL OXIDATIVE DAMAGE | RAT-BRAIN | COX-2 inhibitors | Enzymes | Unsaturated fatty acids | Prostaglandins | Brain research | Linoleic acids | Phospholipases | Mitogens | Essential fatty acids | Brain | Dietary minerals | Disorders | Eicosanoids | Prostaglandin E2 | Ventricles (cerebral) | Lipids | Arachidonic acid | Immunity | Lipopolysaccharides | Prostaglandin endoperoxide synthase | Rodents | Bacteria | Phospholipase A2 | Markers | Rats | Metabolism | Variance analysis | Linoleic acid | Phospholipase | Diet | Cyclooxygenase-1 | Cyclooxygenase-2 | Lipoxygenase
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