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1. Full Text Effect of altered dietary n-3 fatty acid intake upon plasma lipid fatty acid composition, conversion of [13C]α-linolenic acid to longer-chain fatty acids and partitioning towards β-oxidation in older men
by Burdge, Graham C and Finnegan, Yvonne E and Minihane, Anne M and Williams, Christine M and Wootton, Stephen A
British Journal of Nutrition, ISSN 0007-1145, 8/2003, Volume 90, Issue 2, pp. 311 - 321
The effect of increased dietary intakes of alpha-linolenic acid (ALNA) or eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) for 2 months upon plasma... 
Dietary n-3 polyunsaturated fatty acids | Stable isotope | α-Linoleic acid | Man | alpha-linolenic acid | RISK-FACTORS | METABOLIC DISPOSAL | YOUNG MEN | PLATELET-FUNCTION | HUMANS | stable isotope | NUTRITION & DIETETICS | OIL | IN-VIVO | dietary n-3 polyunsaturated fatty acids | man | EICOSAPENTAENOIC ACID | DOCOSAHEXAENOIC ACIDS | Carbon Dioxide - metabolism | Oxidation-Reduction | Humans | Middle Aged | Eicosapentaenoic Acid - metabolism | Male | Eicosapentaenoic Acid - administration & dosage | Docosahexaenoic Acids - administration & dosage | Dietary Fats, Unsaturated - metabolism | Lipids - blood | alpha-Linolenic Acid - metabolism | Dietary Fats, Unsaturated - administration & dosage | Fatty Acids - blood | alpha-Linolenic Acid - administration & dosage | Docosahexaenoic Acids - metabolism | Fatty Acids, Unsaturated - administration & dosage
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2. Full Text Influence of dietary linoleic acid (18:2n‐6) and α‐linolenic acid (18:3n‐3) ratio on fatty acid composition of different tissues in freshwater fish Songpu mirror carp, Cyprinus Carpio
by Tian, Jing‐Jing and Lei, Cai‐Xia and Ji, Hong
Aquaculture Research, ISSN 1355-557X, 12/2016, Volume 47, Issue 12, pp. 3811 - 3825
Six isonitrogenous and isoenergetic purified diets were formulated to feed Songpu mirror carp for 60 days. The control diet (CD) was only supplemented with... 
α‐linolenic acid | fatty acid analysis | linoleic acid | Cyprinus Carpio | α-linolenic acid | alpha-linolenic acid | SEABREAM SPARUS-AURATA | DESATURASE | Cyprinus Carpiod | NUTRITIONAL REGULATION | ARACHIDONIC-ACID | REPLACEMENT | FISHERIES | METABOLISM | GROWTH | ONTOGENY | SALMON SALMO-SALAR | MARINE
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3. Full Text Dietary n − 6 and n − 3 polyunsaturated fatty acids: From biochemistry to clinical implications in cardiovascular prevention
by Russo, Gian Luigi
Biochemical Pharmacology, ISSN 0006-2952, 2009, Volume 77, Issue 6, pp. 937 - 946
Linoleic acid (LA) and alpha linolenic acid (ALA) belong to the − 6 (omega-6) and − 3 (omega-3) series of polyunsaturated fatty acids (PUFA), respectively.... 
n − 6 (omega-6) fatty acids | n − 3 (omega-3) fatty acids docosahexaenoic acid | Polyunsaturated fatty acids | Alpha-linolenic acid | Cardiovascular disease | Arachidonic acid | Eicosapentaenoic acid | Essential fatty acids | Linoleic acid | n - 3 (omega-3) fatty acids docosahexaenoic acid | n - 6 (omega-6) fatty acids | HEALTHY-SUBJECTS | NUTRITIONAL REGULATION | n-6 (omega-6) fatty acids | SECONDARY PREVENTION | X-RECEPTOR LXR | docosahexaenoic acid | ACUTE MYOCARDIAL-INFARCTION | n-3 (omega-3) fatty acids | PHARMACOLOGY & PHARMACY | FISH-OIL | CORONARY-HEART-DISEASE | Dietary Fats - metabolism | Cardiovascular Diseases - diet therapy | Fatty Acids, Omega-3 - metabolism | Cardiovascular Diseases - metabolism | Cardiovascular Diseases - prevention & control | Humans | Fatty Acids, Omega-3 - chemistry | Fatty Acids, Unsaturated - metabolism | Fatty Acids, Omega-6 - metabolism | Fatty Acids, Omega-6 - administration & dosage | Animals | Fatty Acids, Omega-6 - chemistry | Fatty Acids, Unsaturated - chemistry | Dietary Fats - administration & dosage | Fatty Acids, Omega-3 - administration & dosage | Fatty Acids, Unsaturated - administration & dosage | Prevention | Oleic acid | Low density lipoproteins | Dietary supplements | Physiological aspects | Lipids | Biochemistry | Coronary heart disease
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4. Full Text Distribution, interconversion, and dose response of n-3 fatty acids in humans
by Arterburn, Linda M and Hall, Eileen Bailey and Oken, Harry
American Journal of Clinical Nutrition, ISSN 0002-9165, 06/2006, Volume 83, Issue 6, pp. 1467S - 1476S
n-3 Fatty acids have important visual, mental, and cardiovascular health benefits throughout the life cycle. Biodistribution, interconversion, and dose... 
Human dose response | n-3 fatty acids | Docosahexaenoic acid | Eicosapentaenoic acid | α-linolenic acid | alpha-linolenic acid | RANDOMIZED CLINICAL-TRIAL | OMEGA-3-FATTY-ACID DOCOSAHEXAENOIC ACID | PLASMA-LIPID FRACTIONS | TERM INFANTS | eicosapentaenoic acid | NUTRITION & DIETETICS | docosahexaenoic acid | FISH-OIL | human dose response | BREAST-FED INFANTS | RETINITIS-PIGMENTOSA | ADIPOSE-TISSUE | Humans | alpha-Linolenic Acid - pharmacokinetics | Eicosapentaenoic Acid - administration & dosage | Erythrocytes - chemistry | Docosahexaenoic Acids - administration & dosage | Docosahexaenoic Acids - pharmacokinetics | Milk, Human - chemistry | Organ Specificity | Dose-Response Relationship, Drug | Tissue Distribution | Eicosapentaenoic Acid - blood | Fatty Acids, Omega-3 - pharmacokinetics | Docosahexaenoic Acids - blood | Eicosapentaenoic Acid - pharmacokinetics | Erythrocytes - metabolism | Fatty Acids, Omega-3 - blood | alpha-Linolenic Acid - administration & dosage | Dietary Supplements | Fatty Acids, Omega-3 - administration & dosage | alpha-Linolenic Acid - blood | Nutritional aspects | Usage | Omega-3 fatty acids
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5. Full Text Serum n-3 Tetracosapentaenoic Acid and Tetracosahexaenoic Acid Increase Following Higher Dietary α-Linolenic Acid but not Docosahexaenoic Acid
by Metherel, Adam H and Domenichiello, Anthony F and Kitson, Alex P and Lin, Yu-Hong and Bazinet, Richard P
Lipids, ISSN 0024-4201, 2/2017, Volume 52, Issue 2, pp. 167 - 172
n-3 Tetracosapentaenoic acid (24:5n-3, TPAn-3) and tetracosahexaenoic acid (24:6n-3, THA) are believed to be important intermediates to docosahexaenoic acid... 
Life Sciences | Neurochemistry | Medicinal Chemistry | Tetracosahexaenoic acid | Lipidology | n-3 Tetracosapentaenoic acid | Nutrition | Microbial Genetics and Genomics | Medical Biochemistry | Serum | Docosahexaenoic acid | α-Linolenic acid | α‐Linolenic acid | n‐3 Tetracosapentaenoic acid | RAT-LIVER | alpha-Linolenic acid | BIOCHEMISTRY & MOLECULAR BIOLOGY | RETROCONVERSION | DEFICIENCY | NUTRITION & DIETETICS | PLASMA | METABOLISM | BIOSYNTHESIS | POLYUNSATURATED FATTY-ACIDS | DHA | EICOSAPENTAENOIC ACID | BRAIN | Animals | Biosynthetic Pathways - drug effects | Docosahexaenoic Acids - blood | Gas Chromatography-Mass Spectrometry | Rats, Long-Evans | Rats | Male | Docosahexaenoic Acids - administration & dosage | alpha-Linolenic Acid - administration & dosage
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6. Full Text Effect of maternal micronutrients (folic acid, vitamin B12 ) and omega 3 fatty acids on liver fatty acid desaturases and transport proteins in Wistar rats
by Wadhwani, Nisha S and Manglekar, Rupali R and Dangat, Kamini D and Kulkarni, Asmita V and Joshi, Sadhana R
Prostaglandins, Leukotrienes and Essential Fatty Acids, ISSN 0952-3278, 2011, Volume 86, Issue 1, pp. 21 - 27
Abstract A disturbed fatty acid metabolism increases the risk of adult non-communicable diseases. This study examines the effect of maternal micronutrients on... 
Endocrinology & Metabolism | Advanced Basic Science | Δ6 desaturase | Micronutrients | FABP3 | FATP1 | Δ5 desaturase | MOTHERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Delta 5 desaturase | DEFICIENCY | CELL BIOLOGY | PLASMA | METABOLISM | DOCOSAHEXAENOIC ACID | ENDOCRINOLOGY & METABOLISM | LIPID-COMPOSITION | Delta 6 desaturase | DELTA-5 | EXPRESSION | ALPHA-LINOLENIC ACID | ADIPOSE-TISSUE | Folic Acid - pharmacology | Gene Expression - drug effects | Rats, Wistar | Folic Acid - administration & dosage | Vitamins - pharmacology | Linoleoyl-CoA Desaturase - genetics | RNA - genetics | Liver - drug effects | Time Factors | Fatty Acids, Omega-3 - pharmacology | Female | Weight Gain - drug effects | Micronutrients - administration & dosage | Fatty Acids - metabolism | Fatty Acids, Omega-3 - administration & dosage | RNA - metabolism | Vitamin B 12 - administration & dosage | Fatty Acid Desaturases - genetics | Fatty Acid Desaturases - metabolism | Liver - metabolism | Vitamin B 12 - pharmacology | Rats | Linoleoyl-CoA Desaturase - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Fatty Acid-Binding Proteins - genetics | Pregnancy | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Micronutrients - pharmacology | Fatty Acid Binding Protein 3 | Dietary Supplements | Vitamins - administration & dosage | Unsaturated fatty acids | Messenger RNA | Carrier proteins | Liver | Fatty acid desaturases | Physiological aspects | Omega-3 fatty acids | Folic acid
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7. Full Text Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids
by Gibson, R.A and Neumann, M.A and Lien, E.L and Boyd, K.A and Tu, W.C
Prostaglandins, Leukotrienes and Essential Fatty Acids, ISSN 0952-3278, 2012, Volume 88, Issue 1, pp. 139 - 146
Abstract The conversion of the plant-derived omega-3 (n-3) α-linolenic acid (ALA, 18:3n-3) to the long-chain eicosapentaenoic acid (EPA, 20:5n-3) and... 
Endocrinology & Metabolism | Advanced Basic Science | Docosahexaenoic acid (DHA) | Alpha linolenic acid (ALA) | LA:ALA ratio | Linoleic acid (LA) | RAT-LIVER | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMANS | CELL BIOLOGY | TERM INFANTS | VISUAL-ACUITY DEVELOPMENT | PLASMA | BIOSYNTHESIS | GROWTH | ENDOCRINOLOGY & METABOLISM | FISH-OIL | EICOSAPENTAENOIC ACID | Linoleic Acid - blood | Linoleic Acid - administration & dosage | Fatty Acids, Omega-6 - blood | Rats, Wistar | alpha-Linolenic Acid - analysis | Linoleic Acid - metabolism | Weaning | Safflower Oil - chemistry | Diet, High-Fat - adverse effects | Safflower Oil - metabolism | Male | Safflower Oil - administration & dosage | Linoleic Acid - adverse effects | Fatty Acids, Essential - deficiency | Fatty Acids, Essential - blood | Phospholipids - blood | Fatty Acids, Unsaturated - analysis | Phospholipids - metabolism | Plant Oils - administration & dosage | alpha-Linolenic Acid - administration & dosage | alpha-Linolenic Acid - blood | Fatty Acids, Essential - metabolism | Safflower Oil - adverse effects | Eicosapentaenoic Acid - metabolism | Phospholipids - chemistry | Rats | Fatty Acids, Omega-6 - metabolism | Linseed Oil - chemistry | Plant Oils - adverse effects | Eicosapentaenoic Acid - blood | Fatty Acids, Unsaturated - blood | Algorithms | Animals | Docosahexaenoic Acids - blood | Fatty Acids, Omega-6 - chemistry | Sunflower Oil | Linseed Oil - metabolism | Diet, Fat-Restricted | Fatty Acids, Unsaturated - adverse effects | Plant Oils - metabolism | alpha-Linolenic Acid - metabolism | Plant Oils - chemistry | Linseed Oil - administration & dosage | Docosahexaenoic Acids - metabolism | Fatty Acids, Omega-6 - adverse effects | Fatty Acids, Unsaturated - administration & dosage | Omega-3 fatty acids | Linolenic acids
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8. Full Text Fatty acids from fish: the anti‐inflammatory potential of long‐chain omega‐3 fatty acids
by Wall, Rebecca and Ross, R Paul and Fitzgerald, Gerald F and Stanton, Catherine
Nutrition Reviews, ISSN 0029-6643, 05/2010, Volume 68, Issue 5, pp. 280 - 289
Omega‐6 (n‐6) and omega‐3 (n‐3) polyunsaturated fatty acids (PUFA) are precursors of potent lipid mediators, termed eicosanoids, which play an important role... 
anti‐inflammatory | omega‐3 | DHA | EPA | fish oil | Omega-3 | Anti-inflammatory | Fish oil | INFLAMMATORY PROCESSES | DIETARY-INTAKE | OIL SUPPLEMENTATION | TUMOR-NECROSIS-FACTOR | COGNITIVE DECLINE | NUTRITION & DIETETICS | omega-3 | DOCOSAHEXAENOIC ACID | anti-inflammatory | CARDIOVASCULAR-DISEASE | CORONARY-HEART-DISEASE | EICOSAPENTAENOIC ACID | ALPHA-LINOLENIC ACID | Fatty Acids, Omega-3 - metabolism | Nutritive Value | Humans | Fatty Acids, Omega-6 - metabolism | Chronic Disease - prevention & control | Fatty Acids, Omega-3 - analysis | Fatty Acids, Omega-6 - administration & dosage | Inflammation - metabolism | Animals | Fishes | Fatty Acids, Omega-6 - analysis | Inflammation - prevention & control | Seafood - analysis | Fatty Acids, Omega-3 - administration & dosage | Prevention | Composition | Nutritional aspects | Chronic diseases | Fish as food | Health aspects | Omega-3 fatty acids | Näringslära | Medical and Health Sciences | Medicin och hälsovetenskap | Hälsovetenskaper | Nutrition and Dietetics | Health Sciences
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9. Full Text Effects of dietary n-6:n-3 PUFA ratio on fatty acid composition, free amino acid profile and gene expression of transporters in finishing pigs
by Li, Fengna and Duan, Yehui and Li, Yinghui and Tang, Yulong and Geng, Meimei and Oladele, Oso Abimbola and Kim, Sung Woo and Yin, Yulong
British Journal of Nutrition, ISSN 0007-1145, 03/2015, Volume 113, Issue 5, pp. 739 - 748
Revealing the expression patterns of fatty acid and amino acid transporters as affected by dietary n-6:n-3 PUFA ratio would be useful for further clarifying... 
n-6:n-3 PUFA ratios | Transporters | Amino acids | Finishing pigs | Fatty acids | PROTEIN | N-3 PUFA | INSULIN | n-3 PUFA ratios | NUTRITION & DIETETICS | SKELETAL-MUSCLE CELLS | METABOLISM | n-6 | DOCOSAHEXAENOIC ACID | LIPID-COMPOSITION | ALPHA-LINOLENIC ACID | ADIPOSE-TISSUE | LINSEED | Large Neutral Amino Acid-Transporter 1 - metabolism | Muscle, Skeletal - metabolism | Soybean Oil - metabolism | Fatty Acids, Omega-3 - analysis | Amino Acids - metabolism | Fatty Acids, Omega-6 - administration & dosage | Muscle Development | Subcutaneous Fat - metabolism | Fatty Acid Transport Proteins - metabolism | Protein Isoforms - metabolism | Sus scrofa - metabolism | Gene Expression Regulation, Developmental | Dietary Fats - analysis | Soybean Oil - administration & dosage | Fatty Acids, Omega-6 - analysis | Amino Acid Transport System A - genetics | Weight Gain | Fatty Acids - metabolism | Diet - veterinary | Fatty Acids, Omega-3 - administration & dosage | Fatty Acids, Omega-3 - metabolism | Muscle, Skeletal - growth & development | Meat - analysis | Amino Acids - analysis | Fatty Acids - analysis | Large Neutral Amino Acid-Transporter 1 - genetics | Sus scrofa - growth & development | Energy Intake | Fatty Acids, Omega-6 - metabolism | Animals | Linseed Oil - metabolism | Subcutaneous Fat - growth & development | Amino Acid Transport System A - metabolism | Fatty Acid Transport Proteins - genetics | Linseed Oil - administration & dosage | Crosses, Genetic | Protein Isoforms - genetics | Hogs | Diet | Gene expression | Metabolism
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10. Full Text Modeled replacement of traditional soybean and canola oil with high-oleic varieties increases monounsaturated fatty acid and reduces both saturated fatty acid and polyunsaturated fatty acid intake in the US adult population
by Raatz, Susan K and Conrad, Zach and Jahns, Lisa and Belury, Martha A and Picklo, Matthew J
The American Journal of Clinical Nutrition, ISSN 0002-9165, 09/2018, Volume 108, Issue 3, pp. 594 - 602
ABSTRACT BACKGROUND High-oleic (HO) seed oils are being introduced as replacements for trans fatty acid (TFA)–containing fats and oils. Negative health effects... 
trans fatty acids | fatty acids | dietary fat | soybean oil | canola oil | high-oleic canola oil | NHANES | high-oleic soybean oil | WWEIA | TRANS FAT | MEDITERRANEAN DIET | DISEASE RISK-FACTORS | AMERICAN-HEART-ASSOCIATION | ALL-CAUSE MORTALITY | NUTRITION & DIETETICS | REDUCTION | CARDIOVASCULAR-DISEASE | COHORT | Linoleic Acid - administration & dosage | alpha-Linolenic Acid - deficiency | Lactation | Nutrition Surveys | Fatty Acids, Monounsaturated - administration & dosage | Humans | Middle Aged | Male | Nutrition Policy | Linoleic Acid - deficiency | Trans Fatty Acids - analysis | Fatty Acids - administration & dosage | Adult | Female | Trans Fatty Acids - administration & dosage | Fatty Acids, Unsaturated - analysis | Oleic Acid - analysis | alpha-Linolenic Acid - administration & dosage | Rapeseed Oil - analysis | Oleic Acid - administration & dosage | Risk Factors | Fatty Acids - analysis | Pregnancy | Diet | Dietary Fats, Unsaturated - administration & dosage | Dietary Fats, Unsaturated - analysis | Soybean Oil - analysis | Aged | Fatty Acids, Unsaturated - administration & dosage | Analysis | Linolenic acids | Dietary fat | Models | Soybean | Saturated fatty acids | Trans fatty acids | Omega-3 fatty acids | Evaluation | Food substitutes | Oleic acid | Soy oil | Canola oil | Nutrition policy | Health aspects | Essential fatty acids | Standards
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11. Full Text Essential Fatty Acids Linoleic Acid and α‐Linolenic Acid Sex‐Dependently Regulate Glucose Homeostasis in Obesity
by Zhuang, Pan and Shou, Qiyang and Wang, Wenqiao and He, Lilin and Wang, Jun and Chen, Jingnan and Zhang, Yu and Jiao, Jingjing
Molecular Nutrition & Food Research, ISSN 1613-4125, 09/2018, Volume 62, Issue 17, pp. e1800448 - n/a
Scope To assess the associations of dietary linoleic acid (LA) and α‐linolenic acid (ALA) with type 2 diabetes (T2D) risk in a population‐based cohort and... 
α‐linolenic acid | linoleic acid | glucose homeostasis | sex dimorphisms | diabetes | obesity | α-linolenic acid | alpha-linolenic acid | DIETARY-FAT | OMEGA-3-FATTY-ACIDS | FOOD SCIENCE & TECHNOLOGY | RISK | LINKING GUT MICROBIOTA | INSULIN-RESISTANCE | INFLAMMATION | DISEASE | METABOLIC ENDOTOXEMIA | MICE | TYPE-2 DIABETES-MELLITUS | Obesity - diet therapy | Overweight - complications | Obesity - complications | Humans | Mice, Inbred C57BL | Male | Overweight - diet therapy | Gastrointestinal Microbiome - genetics | Obesity - metabolism | alpha-Linolenic Acid - pharmacology | Overweight - metabolism | Animals | Gastrointestinal Microbiome - drug effects | China | Sex Factors | Adult | Diabetes Mellitus, Type 2 - etiology | Female | Homeostasis - drug effects | Linoleic Acid - pharmacology | Blood Glucose - metabolism | Longitudinal Studies | Obesity | Nutrition | Body weight | Diabetes mellitus | Sex | Health risks | Homeostasis | Intakes | Fatty acids | High fat diet | Linoleic acid | Confidence intervals | Microbiota | Linolenic acid | Diet | Body mass | Risk assessment | Rodents | Quartiles | Mice | Adults | Diabetes mellitus (non-insulin dependent) | Endotoxemia
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