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Clinical Immunology, ISSN 1521-6616, 2015, Volume 168, pp. 6 - 15
Abstract In the present study, the combined adjuvant effect of 7DW8-5, a potent α-GalCer-analog, and MPLA, a TLR4 agonist, on the induction of vaccine-induced... 
Allergy and Immunology | Cancer vaccine | NKT cells | Malaria vaccine | Memory-like effector NKT cells | WT-1 | Adjuvant | CD1d | TLR4 | Circumsporozoite protein | Glycolipid | GENE WT1 PRODUCT | DENDRITIC CELLS | IMMUNOLOGY | CANCER | TUMOR-IMMUNITY | PROTECTIVE IMMUNITY | IMMUNE-RESPONSES | IN-VIVO | TOLL-LIKE RECEPTORS | MICE | HLA-A2 Antigen - genetics | Humans | Lipid A - analogs & derivatives | Interferon-gamma - metabolism | Galactosylceramides - administration & dosage | Galactosylceramides - pharmacology | Protective Agents - pharmacology | WT1 Proteins - immunology | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Toll-Like Receptor 4 - agonists | Protozoan Proteins - chemistry | Epitopes, T-Lymphocyte - immunology | WT1 Proteins - genetics | Immunologic Memory - immunology | Amino Acid Sequence | Lipid A - administration & dosage | Plasmodium yoelii - physiology | HLA-A2 Antigen - immunology | Immunization - methods | Malaria - immunology | Mice, Inbred C57BL | Peptides - immunology | Mice, Transgenic | Plasmodium yoelii - immunology | Toll-Like Receptor 4 - metabolism | Drug Synergism | Malaria - prevention & control | Models, Immunological | Animals | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Lipid A - pharmacology | Malaria - parasitology | Cell Line, Tumor | Killer Cells, Natural - drug effects | Mice, Inbred BALB C | Killer Cells, Natural - metabolism | Protective Agents - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Protozoan Proteins - immunology
Journal Article
Organic Letters, ISSN 1523-7060, 2019, Volume 21, Issue 9, pp. 2988 - 2992
A convergent and rapid synthesis of original C2,C3-unsaturated, C11,C13-keto-enol macrocycles with a peloruside A skeleton has been developed. These original... 
AGENT | CHEMISTRY, ORGANIC | Chemical Sciences
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 26, pp. 2804 - 2810
Highlights • Liposomes with monophosphoryl lipid A were formulated as adjuvants for haptens. • Heroin analog haptens were conjugated either to the liposomes or... 
Allergy and Immunology | Opiate vaccine | Adjuvant system | Antibodies to heroin haptens | Liposomes containing monophosphoryl lipid A | MEDICINE, RESEARCH & EXPERIMENTAL | SPECIFICITIES | CHOLESTEROL | RATS | ANTIGENS | ALUMINUM-HYDROXIDE | IMMUNOLOGY | DRUG-ABUSE | RELAPSE | PEPTIDES | MORPHINE/HEROIN VACCINE | CODEINE | Adjuvants, Immunologic - administration & dosage | HIV Envelope Protein gp41 - immunology | Lipid A - analogs & derivatives | HIV Envelope Protein gp41 - chemistry | Haptens - immunology | Feasibility Studies | Haptens - chemistry | Lipid A - immunology | Tetanus Toxoid - chemistry | Adjuvants, Immunologic - chemistry | Female | Opioid-Related Disorders - prevention & control | Epitopes, T-Lymphocyte - immunology | Lipid A - chemistry | Lipid A - administration & dosage | Peptides - chemistry | Peptides - immunology | Vaccines - immunology | Heroin - immunology | Opioid-Related Disorders - immunology | Epitopes, T-Lymphocyte - chemistry | Animals | Antibody Formation | Mice | Mice, Inbred BALB C | Liposomes | Tetanus Toxoid - immunology | Viral antibodies | Drug abuse | Alcoholism | Antibodies | Lipids | Tetanus | Heroin | Competition | Peptides | Aluminum | Amino acids | Vaccines | Proteins | Studies | Immunology | Alzheimers disease | Laboratory animals | Binding sites | Cancer | adjuvant system | opiate vaccine | antibodies to heroin haptens
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2018, Volume 28, Issue 4, pp. 594 - 600
Gram-negative bacteria comprise the majority of microbes that cause infections that are resistant to pre-existing antibiotics. The complex cell wall... 
Structural rearrangement | GT-B | Inhibition kinetics | Inhibitor design | Glycosyltransferase | Allosterism | Lipopolysaccharide | Heptosyltransferase | AutoDock Vina | LPS | CAMPYLOBACTER-JEJUNI | GLYCOSIDES | CHEMISTRY, MEDICINAL | WAAC | LIPOPOLYSACCHARIDE-BINDING PROTEIN | CHEMISTRY, ORGANIC | MECHANISMS | HEPTOSE | CLONING | BIOSYNTHESIS | GLYCOSYLTRANSFERASES | ENDOTOXINS | Glucosides - pharmacology | Escherichia coli - enzymology | Lipid A - chemical synthesis | Glycosyltransferases - chemistry | Lipid A - analogs & derivatives | Enzyme Inhibitors - pharmacology | Galactosides - chemical synthesis | Galactosides - chemistry | Enzyme Inhibitors - chemical synthesis | Anti-Bacterial Agents - chemical synthesis | Galactosides - pharmacology | Glucosides - chemical synthesis | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Lipid A - pharmacology | Glucosides - chemistry | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Escherichia coli Proteins - antagonists & inhibitors | Kinetics | Escherichia coli Proteins - chemistry | Binding Sites | Lipid A - chemistry | Glycosyltransferases - antagonists & inhibitors | Membrane lipids | Enzymes | Drug resistance in microorganisms | Escherichia coli | Physiological aspects | Bacteria | Cross infection | Nosocomial infections | Mitogens | Fructose | Inhibitor Design | Structural Rearrangement | Inhibition Kinetics
Journal Article