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EMBO reports, ISSN 1469-221X, 01/2018, Volume 19, Issue 1, pp. 57 - 72
Eukaryotic cells store lipids in cytosolic organelles known as lipid droplets (LDs). Lipid droplet bud from the endoplasmic reticulum (ER), and may be... 
lipid droplet | membrane contact site | nutritional stress | endoplasmic reticulum | nuclear ER–vacuole junction | STORAGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SACCHAROMYCES-CEREVISIAE | MASS-SPECTROMETRY | CELL BIOLOGY | YEAST | nuclear ER-vacuole junction | JUNCTIONS | SITES | SCALE | PROTEINS | EXPRESSION | Vacuoles - ultrastructure | Triglycerides - biosynthesis | Coenzyme A Ligases - genetics | Fatty Acid Synthases - metabolism | Cytosol - drug effects | Stress, Physiological | Endoplasmic Reticulum - metabolism | Saccharomyces cerevisiae - drug effects | Saccharomyces cerevisiae - ultrastructure | Time-Lapse Imaging | Vacuoles - drug effects | Endoplasmic Reticulum - ultrastructure | Coenzyme A Ligases - metabolism | Saccharomyces cerevisiae - metabolism | Lipid Droplets - ultrastructure | Cerulenin - pharmacology | Endoplasmic Reticulum - drug effects | Intermediate Filament Proteins - genetics | Lipid Metabolism - genetics | Glycerol - pharmacology | Acetic Acid - metabolism | Culture Media - chemistry | Lipid Droplets - metabolism | Fatty Acid Synthases - genetics | Gene Expression Regulation, Fungal | Transformation, Genetic | Lipid Droplets - drug effects | Acetic Acid - pharmacology | Glucose - pharmacology | Receptors, Cytoplasmic and Nuclear - genetics | Saccharomyces cerevisiae Proteins - genetics | Plasmids - metabolism | Glucose - deficiency | Glycerol - metabolism | Culture Media - pharmacology | Lipid Metabolism - drug effects | Plasmids - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Vacuoles - metabolism | Cytosol - metabolism | Intermediate Filament Proteins - metabolism | Fatty Acids - biosynthesis | Receptors, Cytoplasmic and Nuclear - metabolism | Starvation | Nutrient deficiency | Yeast | Lipids | Tethering | Biosynthesis | Metabolism | Organelles | Fatty acids | Stress | Contact stresses | Budding | Endoplasmic reticulum | Membrane & Intracellular Transport
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 01/2018, Volume 233, Issue 1, pp. 302 - 312
Melatonin, the major pineal secretory product, has a significant impact on the female reproductive system. Recently, the beneficial effects of melatonin on... 
mitochondrial quiescence | DNA methyltransferase 1 | in vitro maturation | oocyte | melatonin | OXIDATIVE STRESS | PHYSIOLOGY | FOLLICULAR-FLUID | BOVINE OOCYTES | CELL BIOLOGY | EMBRYO DEVELOPMENT | DNA | MOUSE OOCYTES | COPY NUMBER | PREIMPLANTATION DEVELOPMENT | CUMULUS CELLS | ENERGY-METABOLISM | Lipid Droplets - drug effects | Reactive Oxygen Species - metabolism | DNA, Mitochondrial - metabolism | Oocytes - metabolism | Cells, Cultured | Gene Expression Regulation | Mitochondria - metabolism | Mitochondria - drug effects | Membrane Potential, Mitochondrial - drug effects | Electron Transport Complex IV - metabolism | Triglycerides - metabolism | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA (Cytosine-5-)-Methyltransferases - genetics | DNA Methylation | Animals | DNA, Mitochondrial - genetics | Oocytes - drug effects | Female | Lipid Droplets - metabolism | Melatonin - pharmacology | Sus scrofa | Energy Metabolism - drug effects | In Vitro Oocyte Maturation Techniques | Embryonic development | Melatonin | Methyltransferases | Genes | Triglycerides | Mitochondrial DNA | Methylation | Phosphorylation | Reactive oxygen species | Transcription | Copy number | Lipids | Accumulation | Oocytes | Mitochondria | Reduction | Embryogenesis | Coding | DNA methylation | Droplets | Membrane potential | Deoxyribonucleic acid--DNA | Reproductive systems | Maturation | Pineal gland | DNMT1 protein | Gene expression | Embryonic growth stage | Oxidative phosphorylation | DNA methyltransferase | Reproductive system | Electron transport
Journal Article
Cancer Letters, ISSN 0304-3835, 2017, Volume 401, pp. 39 - 45
Journal Article
Cell Reports, ISSN 2211-1247, 11/2016, Volume 17, Issue 6, pp. 1546 - 1559
Journal Article
Nature Communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, p. 15979
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2017, Volume 292, Issue 28, pp. 11815 - 11828
In liver steatosis (i.e. fatty liver), hepatocytes accumulate many large neutral lipid storage organelles known as lipid droplets (LDs). LDs are important in... 
alcohol | lipid droplet | STIMULATED LIPOLYSIS | ADIPOSE TRIGLYCERIDE LIPASE | HEPATIC GLUCONEOGENESIS | hepatocyte | HORMONE-SENSITIVE LIPASE | PROTEIN-KINASE | ATGL | BIOCHEMISTRY & MOLECULAR BIOLOGY | adrenergic receptor | cyclic AMP (cAMP) | fatty liver | METABOLISM | G protein-coupled receptor (GPCR) | adipose triglyceride lipase (ATGL) | PROMOTES | LIPID DROPLETS | Lipolysis - drug effects | Humans | Sterol Esterase - metabolism | Cyclic AMP-Dependent Protein Kinases - chemistry | Hepatocytes - pathology | Male | Protein Transport - drug effects | Hepatocytes - metabolism | Fatty Liver, Alcoholic - metabolism | Hepatocytes - cytology | Protein Processing, Post-Translational - drug effects | Female | Phosphorylation - drug effects | Fatty Liver, Alcoholic - pathology | Lipid Droplets - metabolism | Receptors, Adrenergic, beta - metabolism | Sterol Esterase - chemistry | Cyclic AMP - metabolism | Hepatocytes - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Lipid Droplets - drug effects | Receptors, Adrenergic, beta - chemistry | Second Messenger Systems - drug effects | Cells, Cultured | Adrenergic beta-Agonists - pharmacology | Lipid Droplets - pathology | Rats | Lipase - metabolism | Enzyme Activation - drug effects | Lipase - chemistry | Animals | Cell Line, Tumor | Cyclic AMP - agonists | Cell Biology
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 2015, Volume 35, Issue 4, pp. 737 - 746
Lipid droplets (LDs) are intracellular structures that regulate neutral lipid homeostasis. In mammals, LD synthesis is inhibited by rapamycin, a known... 
NITROGEN CATABOLITE REPRESSION | TRANSCRIPTION FACTORS | MAMMALIAN TARGET | RAPAMYCIN | 2 PROTEIN PHOSPHATASES | LIPOLYSIS | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | CELLULAR-ENERGY | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | Cholesterol Esters - metabolism | Osmotic Pressure | Triglycerides - biosynthesis | Saccharomyces cerevisiae - genetics | Transcription Factors - deficiency | Saccharomyces cerevisiae - drug effects | GATA Transcription Factors - deficiency | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Saccharomyces cerevisiae - metabolism | Lipid Droplets - metabolism | Lipid Droplets - chemistry | Gene Expression Regulation, Fungal | Lipid Droplets - drug effects | Signal Transduction | Saccharomyces cerevisiae Proteins - antagonists & inhibitors | Protein Phosphatase 2 - genetics | Transcription Factors - antagonists & inhibitors | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | GATA Transcription Factors - genetics | Sirolimus - pharmacology | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Lipid Metabolism - drug effects | Protein Phosphatase 2 - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Sorbitol - pharmacology
Journal Article