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Nature, ISSN 0028-0836, 03/2017, Volume 543, Issue 7645, pp. 385 - 390
Journal Article
Gut, ISSN 0017-5749, 05/2017, Volume 66, Issue 5, pp. 823 - 838
ObjectiveInterleukin (IL)-36R signalling plays a proinflammatory role in different organs including the skin, but the expression of IL-36R ligands and their... 
STEM-CELLS | IL-1-ALPHA | REPAIR | ANTAGONIST | ULCERATIVE-COLITIS | RECEPTOR | MICE | IL-1-BETA | LIGAND | GASTROENTEROLOGY & HEPATOLOGY | INFLAMMATORY BOWEL DISEASES | Dextran Sulfate | Intestinal Mucosa - metabolism | Cell Proliferation | Epithelial Cells - metabolism | Lipocalin-2 - biosynthesis | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Colitis - genetics | Humans | Receptors, Interleukin-1 - genetics | Cytoplasm - metabolism | Wound Healing | Inflammatory Bowel Diseases - metabolism | Receptors, Interleukin - metabolism | Cell Nucleus - metabolism | Colitis - chemically induced | Interleukin-6 - metabolism | Fibroblasts - metabolism | Calgranulin B - biosynthesis | Interleukin-1 - metabolism | Cytokines - metabolism | Myeloid Differentiation Factor 88 - genetics | Signal Transduction - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Macrophages - metabolism | Animals | Colitis - metabolism | Ligands | Chemokines - metabolism | Mice | Myeloid Differentiation Factor 88 - metabolism | Fibroblasts | Intestines | Care and treatment | Cellular signal transduction | Research | Epithelial cells | Cell proliferation | Animal models | Mucosa | Genomes | CD14 antigen | Interleukin 6 | Signal transduction | Intestine | Rodents | Tumor necrosis factor-TNF | Colony-stimulating factor | Colon | Wound healing | Bacterial infections | Cytokines | Granulocyte-macrophage colony-stimulating factor | Lipocalin | Inflammation | Epithelium | Ribonucleic acid--RNA | Inflammatory bowel disease | Dextran | Sodium | Biopsy | MyD88 protein | Skin | Colitis | Chemokines | Cytoplasm | Index Medicus | Abridged Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 02/2009, Volume 75, Issue 3, pp. 285 - 294
Urinary neutrophil gelatinase-associated lipocalin (Ngal or lipocalin 2) is a very early and sensitive biomarker of kidney injury. Here we determined the... 
albuminuria | acute renal failure | obstructive nephropathy | diabetic nephropathy | nephrotic syndrome | Diabetic nephropathy | Obstructive nephropathy | Nephrotic syndrome | Albuminuria | Acute renal failure | NGAL | ACUTE KIDNEY INJURY | MOUSE | DIABETIC-NEPHROPATHY | IRON | TISSUE GROWTH-FACTOR | CARDIAC-SURGERY | INSULIN-RESISTANCE | UROLOGY & NEPHROLOGY | ALBUMIN | RENAL INJURY | Acute-Phase Proteins - urine | Biomarkers - urine | Nephrotic Syndrome - urine | Nephritis, Interstitial - urine | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Proto-Oncogene Proteins - urine | Nephrotic Syndrome - metabolism | Lipocalins - urine | Loop of Henle - metabolism | Ureteral Obstruction - metabolism | RNA, Messenger - metabolism | Nephritis, Interstitial - metabolism | Time Factors | Sensitivity and Specificity | Kidney Glomerulus - metabolism | Diabetes Mellitus, Experimental - metabolism | Benzimidazoles - therapeutic use | Disease Models, Animal | Diabetic Nephropathies - urine | Lipocalins - metabolism | Proto-Oncogene Proteins - metabolism | Kidney Tubules, Proximal - cytology | Acute-Phase Proteins - metabolism | Albumins - metabolism | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Animals | Lipocalin-2 | Kidney Tubules, Proximal - metabolism | Tetrazoles - therapeutic use | Mice | Acute Kidney Injury - metabolism | Nephrons - metabolism | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2016, Volume 291, Issue 21, pp. 11216 - 11229
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2014, Volume 289, Issue 24, pp. 16773 - 16789
Lipocalin-2 (LCN2) plays an important role in cellular processes as diverse as cell growth, migration/invasion, differentiation, and death/survival.... 
PATHOGENESIS | MULTIPLE-SCLEROSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | NEURON DEATH | REACTIVE ASTROCYTES | CENTRAL-NERVOUS-SYSTEM | GELATINASE-ASSOCIATED LIPOCALIN | CHEMOKINE RECEPTORS | EXPRESSION | CD8(+) T-CELLS | Oncogene Proteins - genetics | Spinal Cord - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Acute-Phase Proteins - genetics | Interferon-gamma - metabolism | Myelin Sheath - metabolism | Matrix Metalloproteinase 9 - metabolism | T-Lymphocytes - metabolism | Lipocalins - genetics | Matrix Metalloproteinase 9 - genetics | Spinal Cord - pathology | Gene Deletion | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Interferon-gamma - genetics | Neutrophils - metabolism | Dendritic Cells - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Lipocalins - metabolism | Acute-Phase Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Oncogene Proteins - metabolism | Interleukin-17 - genetics | Lymphoid Tissue - metabolism | Receptors, Cell Surface - metabolism | Interleukin-17 - metabolism | Lymphoid Tissue - pathology | Animals | Lipocalin-2 | Myelin Sheath - genetics | Mice | Astrocytes - metabolism | Receptors, Cell Surface - genetics | Index Medicus | Multiple Sclerosis | Autoimmune Disease | Central Nervous System | Neurobiology | EAE | LCN2 | Neuroinflammation | Astrocyte | Microglia
Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 141, Issue 2, pp. 621 - 632
Background & Aims Epithelial cells that cover the intestinal mucosal surface maintain immune homeostasis and tolerance in the gastrointestinal tract. However,... 
Gastroenterology and Hepatology | IgA | Inflammatory Bowel Disease | T Cell | Immune Response | CELLS | COMPLEX | ACTIVATION | POLYMERIC IMMUNOGLOBULIN RECEPTOR | INTESTINAL EPITHELIUM | TRANSPORT | INFLAMMATORY-BOWEL-DISEASE | ADAPTER | HOST-DEFENSE | INFECTION | GASTROENTEROLOGY & HEPATOLOGY | Tumor Necrosis Factor-alpha - metabolism | Intestinal Mucosa - metabolism | Adaptor Protein Complex mu Subunits - metabolism | Epithelial Cells - metabolism | Adaptor Protein Complex beta Subunits - deficiency | Humans | Cell Membrane Permeability | Crohn Disease - metabolism | Cell Membrane - physiology | Ribonucleases - metabolism | Adaptor Protein Complex 1 - metabolism | Th17 Cells - metabolism | Intestinal Mucosa - immunology | alpha-Defensins - metabolism | Adaptor Protein Complex beta Subunits - immunology | Cell Membrane - metabolism | beta-Defensins - metabolism | Colon | Receptors, Cytokine - metabolism | Colitis - immunology | Adaptor Protein Complex 1 - deficiency | Lipocalins - metabolism | Adaptor Protein Complex 1 - immunology | Immunoglobulin A - metabolism | Signal Transduction | Acute-Phase Proteins - metabolism | Down-Regulation | Oncogene Proteins - metabolism | Homeostasis - immunology | Epithelial Cells - pathology | S100 Proteins - metabolism | Muramidase - metabolism | Intestinal Mucosa - microbiology | Mice, Knockout | Interleukin-17 - metabolism | Adaptor Protein Complex beta Subunits - metabolism | Animals | Colitis - microbiology | Proteins - metabolism | Ribonuclease, Pancreatic - metabolism | Lipocalin-2 | Cathelicidins - metabolism | Epithelial Cells - immunology | Receptors, Cytokine - immunology | Mice | Intestinal Mucosa - pathology | Medical colleges | Fc receptors | Gastrointestinal diseases | Homeostasis | Biological response modifiers | Immunoglobulin A | T cells | Index Medicus | Abridged Index Medicus
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 05/2018, Volume 46, Issue 4, pp. 1628 - 1642
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2014, Volume 289, Issue 32, pp. 22063 - 22077
In this study, we report that lipocalin 2 (Lcn2), a recently characterized adipokine/cytokine, is a novel regulator of brown adipose tissue (BAT) activation by... 
ENERGY-EXPENDITURE | ADIPOCYTES | COLD-EXPOSURE | MITOCHONDRIAL BIOGENESIS | PROTEIN-KINASE | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUCOSE-TRANSPORT | ADULT HUMANS | P38 MAP KINASE | ADIPOSE-TISSUE | Oncogene Proteins - genetics | Thermogenesis - genetics | Phosphorylation | Adipocytes, Brown - metabolism | Catecholamines - metabolism | Ion Channels - genetics | Mitochondrial Proteins - genetics | Acute-Phase Proteins - genetics | PPAR gamma - metabolism | Thermogenesis - physiology | Lipocalins - genetics | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | p38 Mitogen-Activated Protein Kinases - metabolism | Acute-Phase Proteins - deficiency | Lipocalins - metabolism | Gene Expression | Oxidation-Reduction | Acute-Phase Proteins - metabolism | Mice, Inbred C57BL | Oncogene Proteins - metabolism | Lipid Metabolism | Mitochondria - metabolism | Transcription Factors - genetics | Peroxisomes - metabolism | Mice, Knockout | Transcription Factors - metabolism | Animals | Ion Channels - metabolism | Lipocalin-2 | Oncogene Proteins - deficiency | Adipose Tissue, Brown - metabolism | Mice | Uncoupling Protein 1 | Index Medicus | Lipocalin 2 | Mitochondria | Thermogenesis | Brown Adipose Tissue | Mitochondrial Biogenesis and Oxidation | Gene Knock-out | Peroxisome | Metabolism | Adipose Tissue | p38 MAPK | Peroxisomal Oxidation
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 02/2013, Volume 98, Issue 2, pp. E388 - E396
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 01/2006, Volume 26, Issue 1, pp. 136 - 142
OBJECTIVE—Neutrophil gelatinase-associated lipocalin (NGAL) modulates the activity of matrix metalloproteinase (MMP) 9, an important mediator of vascular... 
Myocardial infarction | Hypoxia | Matrix metalloproteinase | Remodeling | Atherosclerosis | atherosclerosis | hypoxia | remodeling | myocardial infarction | PLAQUE DISRUPTION | LEUKOCYTE ACTIVATION | MICE LACKING | APOLIPOPROTEIN-E | MATRIX METALLOPROTEINASES | PLASMA | GROWTH-FACTORS | matrix metalloproteinase | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | CORONARY-ARTERY-DISEASE | SMOOTH-MUSCLE CELLS | INFLAMMATORY MEDIATORS | Carotid Arteries - metabolism | Immunohistochemistry | Oncogene Proteins - genetics | Mammary Arteries - metabolism | Humans | Carotid Artery Diseases - physiopathology | Male | Acute-Phase Proteins - genetics | Aorta - metabolism | RNA, Messenger - metabolism | Hypoxia - metabolism | Matrix Metalloproteinase 9 - metabolism | Lipocalins | Coronary Artery Disease - physiopathology | Mice, Mutant Strains | Myocardial Infarction - physiopathology | Carotid Artery Diseases - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, LDL - genetics | Acute-Phase Proteins - metabolism | Coronary Artery Disease - metabolism | Mice, Inbred C57BL | Cells, Cultured | Oncogene Proteins - metabolism | Proto-Oncogene Proteins - genetics | Macrophages - cytology | Myocardial Infarction - metabolism | Aorta - pathology | Gene Expression Regulation, Enzymologic | Macrophages - metabolism | Animals | Lipocalin-2 | Apolipoproteins E - genetics | Hypoxia - physiopathology | Mice | Index Medicus
Journal Article