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The Journal of clinical investigation, ISSN 0021-9738, 11/2016, Volume 126, Issue 11, pp. 4372 - 4386
Obese, insulin-resistant states are characterized by a paradoxical pathogenic condition in which the liver appears to be selectively insulin resistant.... 
RAT-LIVER | MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | DE-NOVO LIPOGENESIS | TRANSCRIPTION FACTOR FOXO1 | FATTY LIVER-DISEASE | OB/OB MICE | ELEMENT-BINDING PROTEIN | HEPATIC STEATOSIS | ADIPOSE-TISSUE | PLASMA TRIGLYCERIDES | Glucose Intolerance - metabolism | Glucose-6-Phosphatase - genetics | Fatty Liver - pathology | Humans | Male | Glucose - biosynthesis | Glucose Intolerance - pathology | Fatty Liver - chemically induced | Glycolysis - drug effects | Glycolysis - genetics | Lipogenesis - genetics | Female | Glucose Intolerance - chemically induced | Insulin - genetics | Nuclear Proteins - genetics | Fatty Liver - genetics | Forkhead Box Protein O1 - metabolism | Glucose Intolerance - genetics | Fatty Liver - metabolism | Fructose - toxicity | Insulin Resistance | Glucose - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Transcription Factors - genetics | Glucose-6-Phosphatase - metabolism | Mice, Knockout | Transcription Factors - metabolism | Insulin - metabolism | Animals | Signal Transduction - drug effects | Lipogenesis - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Forkhead Box Protein O1 - genetics | Obesity | Analysis | Insulin resistance | Genetic aspects | Genetic transcription | Research | Risk factors | Protein binding | Glucose | Metabolites | Rodents | Liver
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 484, Issue 7394, pp. 333 - 338
The prevalence of obesity and type 2 diabetes is increasing worldwide and threatens to shorten lifespan. Impaired insulin action in peripheral tissues is a... 
DIABETES-MELLITUS | FATTY-ACID SYNTHESIS | GENE | INSULIN-RESISTANCE | LIPOGENESIS | MULTIDISCIPLINARY SCIENCES | CARBOHYDRATE-RESPONSE ELEMENT | LIVER | BINDING-PROTEIN CHREBP | UCSC GENOME BROWSER | TRANSGENIC MICE | Transcription Factors - chemistry | Diabetes Mellitus - genetics | Humans | Male | RNA, Messenger - metabolism | Adipose Tissue - metabolism | Protein Isoforms - chemistry | Nuclear Proteins - deficiency | Lipogenesis | Body Mass Index | Glucose Transporter Type 4 - genetics | Adipose Tissue - pathology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry | Genotype | Glucose - pharmacology | Nuclear Proteins - chemistry | Mice, Knockout | Insulin - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Insulin Resistance - genetics | Glucose - metabolism | Mice | Blood Glucose - metabolism | Homeostasis - genetics | Cohort Studies | Diabetes Mellitus - blood | Body Weight | Glucose Transporter Type 4 - metabolism | Transcription Factors - deficiency | Adipose Tissue - cytology | Molecular Sequence Data | Obesity - genetics | Promoter Regions, Genetic - genetics | Protein Isoforms - metabolism | Adiposity | Female | Nuclear Proteins - genetics | Insulin - pharmacology | Glucose Intolerance - genetics | Cross-Sectional Studies | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Cells, Cultured | Diabetes Mellitus - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Obesity - metabolism | Transcription Factors - metabolism | Animals | Glucose Transporter Type 4 - biosynthesis | Adipocytes - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Protein Isoforms - genetics
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 12, p. e28319
Mortierella alpina is an oleaginous fungus which can produce lipids accounting for up to 50% of its dry weight in the form of triacylglycerols. It is used... 
LIPID-ACCUMULATION | MALIC ENZYME | MULTIDISCIPLINARY SCIENCES | PHYLOGENETIC CLASSIFICATION | FATTY-ACID SYNTHASE | ARACHIDONIC-ACID | TANDEM MASS-SPECTROMETRY | HETEROLOGOUS EXPRESSION | QUANTITATIVE-ANALYSIS | SACCHAROMYCES-CEREVISIAE | CELL OIL PRODUCTION | Fungal Proteins - chemistry | Multigene Family - genetics | Protein Structure, Tertiary | Lipids - genetics | Genome, Mitochondrial - genetics | Chromosome Mapping | Fungal Proteins - genetics | Phylogeny | Mortierella - genetics | Reproduction, Asexual - genetics | Genome, Fungal - genetics | Lipogenesis - genetics | Staining and Labeling | Fatty Acids - metabolism | Biological products | Genes | Genomics | Amino acids | Lipids | Genomes | Lipase | Arachidonic acid | Fatty acids | Fungi | Unsaturated fatty acids | Cladistic analysis | Synthesis | Genetically modified organisms | Genetic aspects | Genetic engineering | Biotechnology | Divergence | Atmospheric pressure | Laboratories | Biosynthesis | Biology | Sphingolipids | Food science | Gene sequencing | Next-generation sequencing | Immunology | Lipid metabolism | Catalysis | Lipogenesis | Chemical synthesis | Quantitative analysis | Polypeptides | Triglycerides | Metabolism | Fatty-acid synthase | Cholesterol | Chromatography | Medicine | Chen, Wei | Algorithms | Diet | Scientific imaging | Mass spectrometry | Cancer
Journal Article
Journal Article
BMC genomics, ISSN 1471-2164, 08/2013, Volume 14, Issue 1, pp. 557 - 557
Journal Article
PloS one, ISSN 1932-6203, 2010, Volume 5, Issue 8, p. e12277
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 03/2014, Volume 34, Issue 6, pp. 926 - 938
Classifications Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
INSULIN | TARGET GENES | RAT HEPATOCYTES | CHOLESTEROL | PHOSPHORYLATION | PROTEASOME PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | BOUND TRANSCRIPTION FACTOR | SUMO-1 MODIFICATION | ELEMENT-BINDING PROTEINS | CELL BIOLOGY | Phosphorylation - physiology | Cercopithecus aethiops | Male | Protein Inhibitors of Activated STAT - metabolism | Sumoylation - physiology | Hepatocytes - metabolism | Phosphorylation - genetics | Cyclic AMP-Dependent Protein Kinases - genetics | Lipogenesis - genetics | SUMO-1 Protein - genetics | Protein Inhibitors of Activated STAT - genetics | Lipid Metabolism - genetics | Fasting - metabolism | Ubiquitination - physiology | Lipogenesis - physiology | Hepatocytes - physiology | Sterol Regulatory Element Binding Protein 1 - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Sumoylation - genetics | Fasting - physiology | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Ubiquitin-Protein Ligases - metabolism | Signal Transduction - genetics | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Liver - physiology | Mice, Obese | Signal Transduction - physiology | Mice | SUMO-1 Protein - metabolism | Transcription, Genetic - genetics | Ubiquitin-Protein Ligases - genetics | COS Cells | Lipid Metabolism - physiology | Ubiquitination - genetics
Journal Article