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Cell Stem Cell, ISSN 1934-5909, 11/2016, Volume 19, Issue 5, pp. 613 - 627
Mesenchymal niche cells may drive tissue failure and malignant transformation in the hematopoietic system, but the underlying molecular mechanisms and... 
microenvironment | leukemia | inflammation | mesenchymal | hematopoietic stem cell | shwachman-diamond syndrome | niche | cancer | myelodysplastic syndrome (MDS) | S100A8 | PROGENITOR CELLS | OXIDATIVE DNA-DAMAGE | GENE | SBDS | MUTATIONS | SHWACHMAN-DIAMOND-SYNDROME | MYELODYSPLASTIC CELLS | STROMAL CELLS | EXPRESSION | DEFICIENCY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Bone and Bones - pathology | Inflammation - pathology | Leukemia - pathology | Oxidative Stress | Humans | Hematopoietic Stem Cells - pathology | Precancerous Conditions - metabolism | Leukemia - metabolism | S100 Proteins - genetics | Lipomatosis - pathology | Gene Deletion | Integrases - metabolism | Precancerous Conditions - pathology | Toll-Like Receptors - metabolism | Stem Cell Niche | Pathogen-Associated Molecular Pattern Molecules - metabolism | Signal Transduction | Exocrine Pancreatic Insufficiency - pathology | Risk Factors | Tumor Suppressor Protein p53 - metabolism | Mesenchymal Stromal Cells - metabolism | S100 Proteins - metabolism | Treatment Outcome | Hematopoietic Stem Cells - metabolism | Mitochondria - metabolism | Bone Marrow Diseases - pathology | Disease Progression | Transcription Factors - metabolism | Animals | Proteins - metabolism | DNA Repair | Sp7 Transcription Factor | Mice | DNA Damage | Mesenchymal Stromal Cells - pathology | Bone and Bones - abnormalities | Index Medicus
Journal Article
British Journal of Haematology, ISSN 0007-1048, 07/2018, Volume 182, Issue 1, pp. 114 - 124
Journal Article
Journal Article
Journal Article
Clinical Genetics, ISSN 0009-9163, 10/2016, Volume 90, Issue 4, pp. 334 - 342
Journal Article
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 26, pp. 5143 - 5152
Shwachman-Diamond syndrome (SDS) is an autosomal-recessive marrow failure syndrome with a predisposition to leukemia. SDS patients harbor biallelic mutations... 
YEAST | CELLS | EUKARYOTIC TRANSLATION INITIATION | BLACKFAN ANEMIA | GENE | P53 PROTEIN OVEREXPRESSION | BONE-MARROW | SBDS | HEMATOLOGY | SACCHAROMYCES-CEREVISIAE | HEMATOPOIETIC PROGENITORS | Exocrine Pancreatic Insufficiency - genetics | Exocrine Pancreatic Insufficiency - metabolism | Protein Binding - genetics | Stromal Cells - pathology | Humans | Lipomatosis - metabolism | Gene Knockdown Techniques | Hematopoiesis - drug effects | Transfection | Eukaryotic Initiation Factors - physiology | Lipomatosis - pathology | Protein Binding - drug effects | Protein Multimerization - physiology | Protein Multimerization - genetics | Stromal Cells - drug effects | Bone Marrow Cells - drug effects | Hematopoiesis - physiology | Infant, Newborn | Eukaryotic Initiation Factors - genetics | Eukaryotic Initiation Factors - metabolism | Proteins - physiology | Exocrine Pancreatic Insufficiency - pathology | RNA, Small Interfering - pharmacology | Stromal Cells - metabolism | Bone Marrow Cells - pathology | Cells, Cultured | Bone Marrow Diseases - metabolism | Hematopoiesis - genetics | Bone Marrow Diseases - pathology | Lipomatosis - genetics | Bone Marrow Diseases - genetics | Proteins - genetics | Proteins - metabolism | Bone Marrow Cells - metabolism | Protein Multimerization - drug effects | Ribosome Subunits - metabolism | Index Medicus | Abridged Index Medicus | Hematopoiesis and Stem Cells
Journal Article