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iturin (41) 41
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Journal of Immunology, ISSN 0022-1767, 12/2012, Volume 189, Issue 11, pp. 5442 - 5448
Journal Article
Nature Communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, p. 15203
Inflammasomes regulate innate immune responses by facilitating maturation of inflammatory cytokines, interleukin (IL)-1 beta and IL-18. NACHT, LRR and PYD... 
E3 LIGASE | ACTIVATION | DOMAIN | PROTEIN | STABILITY | MULTIDISCIPLINARY SCIENCES | DISEASE | UBIQUITIN ISOPEPTIDASE | NLRP3 INFLAMMASOME | RECEPTOR DEGRADATION | AMSH | Interleukin-18 - immunology | Lipopeptides - pharmacology | Epithelial Cells - drug effects | Humans | Endosomal Sorting Complexes Required for Transport - genetics | Interleukin-1beta - genetics | Lipopolysaccharides - antagonists & inhibitors | Endosomal Sorting Complexes Required for Transport - immunology | Lysosomes - metabolism | Ubiquitination - drug effects | Inflammasomes - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Endosomal Sorting Complexes Required for Transport - antagonists & inhibitors | Leukocytes, Mononuclear - immunology | Lipopeptides - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - immunology | Epithelial Cells - cytology | Ubiquitin Thiolesterase - antagonists & inhibitors | Lysosomes - drug effects | Cell Line | Leukocytes, Mononuclear - drug effects | Signal Transduction | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | THP-1 Cells | Interleukin-1beta - immunology | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Immunity, Innate | Ubiquitin Thiolesterase - genetics | Inflammasomes - genetics | Epithelial Cells - immunology | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - genetics | Lipopolysaccharides - pharmacology | Leukocytes, Mononuclear - cytology | Molecular Docking Simulation | HeLa Cells | Primary Cell Culture | Interleukin-18 - genetics | Ubiquitin Thiolesterase - immunology
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2006, Volume 177, Issue 3, pp. 1956 - 1966
Human newborns are susceptible to microbial infection and mount poor vaccine responses, yet the mechanisms underlying their susceptibility are incompletely... 
A RECEPTORS | CYTOKINE PRODUCTION | ADENYLYL-CYCLASE | IN-VIVO | CORD BLOOD | TOLL-LIKE RECEPTORS | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | MONOCYTIC CELLS | INNATE IMMUNITY | CUTTING EDGE | Receptor, Adenosine A3 - physiology | Leukocytes, Mononuclear - metabolism | Humans | Adenosine A3 Receptor Antagonists | Cyclic AMP - physiology | Lipoproteins - antagonists & inhibitors | Immunologic Factors - antagonists & inhibitors | Signal Transduction - immunology | Leukocytes, Mononuclear - immunology | Toll-Like Receptors - antagonists & inhibitors | Toll-Like Receptors - physiology | Adult | Receptor, Adenosine A3 - blood | Infant, Newborn | Bacterial Proteins - antagonists & inhibitors | Cyclic AMP - blood | Fetal Blood - immunology | Macrophage Activation - immunology | Immunologic Factors - physiology | Immunologic Factors - blood | Toll-Like Receptors - blood | Adenosine - pharmacology | Fetal Blood - cytology | Lipoproteins - blood | Fetal Blood - metabolism | Adenosine Deaminase - physiology | Bacterial Proteins - pharmacology | Bacterial Proteins - blood | Cyclic AMP - biosynthesis | Up-Regulation - immunology | Lipoproteins - pharmacology | Interleukin-6 - biosynthesis | Leukocytes, Mononuclear - enzymology | Oligopeptides - pharmacology | Lipopeptides | Tumor Necrosis Factor-alpha - biosynthesis | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
Journal of Molecular Graphics and Modelling, ISSN 1093-3263, 07/2015, Volume 60, pp. 1 - 14
Journal Article
BioFactors, ISSN 0951-6433, 05/2017, Volume 43, Issue 3, pp. 388 - 399
Ze339, an herbal extract from Petasites hybridus leaves is effective in treatment of allergic rhinitis by inhibition of a local production of IL‐8 and... 
microbial patterns | human nasal epithelial cells | cytokines | viral inflammation | petasin | STAT signalling | GAMMA | PLACEBO | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE | GRANULOCYTE | INTERMITTENT ALLERGIC RHINITIS | EPITHELIUM | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | EXPRESSION | Epithelial Cells - metabolism | Lipopeptides - pharmacology | Plant Extracts - pharmacology | Epithelial Cells - drug effects | Humans | STAT Transcription Factors - metabolism | Flagellin - pharmacology | Interleukin-4 - pharmacology | Chemokines - antagonists & inhibitors | Lipopeptides - antagonists & inhibitors | Interferon-gamma - antagonists & inhibitors | Nasal Cavity - drug effects | Epithelial Cells - cytology | Plant Leaves - chemistry | Chemokines - biosynthesis | Poly I-C - pharmacology | Interleukin-4 - antagonists & inhibitors | Nasal Cavity - cytology | Signal Transduction | Neutrophils - drug effects | Gene Expression Regulation | Cell Movement - drug effects | STAT Transcription Factors - genetics | Flagellin - antagonists & inhibitors | Nasal Cavity - metabolism | STAT Transcription Factors - antagonists & inhibitors | Primary Cell Culture | Sesquiterpenes - pharmacology | Petasites - chemistry | Interferon-gamma - pharmacology | Poly I-C - antagonists & inhibitors | Allergens | Medicine, Herbal | Anti-inflammatory drugs | Analysis | Medicine, Botanic
Journal Article
Journal Article
Journal Article
CHEMBIOCHEM, ISSN 1439-4227, 01/2014, Volume 15, Issue 2, pp. 243 - 249
Bacillus circulans NRRL B-30644 (now Paenibacillus terrae) was previously reported to produce SRCAM 1580, a bacteriocin active against the food pathogen... 
CHEMISTRY, MEDICINAL | lipopeptides | BIOCHEMISTRY & MOLECULAR BIOLOGY | bacteriocins | peptides | FATTY-ACIDS | GENOME SEQUENCE | antimicrobial agents | BIOSYNTHESIS | RESISTANCE | POLYMYXIN | structure elucidation | BACILLUS | STRAIN
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2005, Volume 174, Issue 3, pp. 1638 - 1646
Cystic fibrosis (CF) is a genetic disease characterized by severe neutrophil-dominated airway inflammation. An important cause of inflammation in CF is... 
IMMUNE-RESPONSE | TOLL-LIKE RECEPTOR-4 | PATTERN-RECOGNITION | DENDRITIC CELLS | SIGNALING PATHWAY | GENE-EXPRESSION | NEUTROPHIL ELASTASE | IMMUNOLOGY | NF-KAPPA-B | BACTERIAL-DNA | CUTTING EDGE | Toll-Like Receptor 2 | Up-Regulation | Receptors, Immunologic - physiology | Toll-Like Receptor 4 | Humans | Membrane Glycoproteins - biosynthesis | Cystic Fibrosis - pathology | Bronchoalveolar Lavage Fluid - immunology | Toll-Like Receptor 9 | Lipopolysaccharides - antagonists & inhibitors | Cystic Fibrosis - immunology | Lipoproteins - antagonists & inhibitors | Toll-Like Receptors | Membrane Glycoproteins - physiology | U937 Cells | Respiratory Mucosa - immunology | Receptors, Cell Surface - physiology | Inflammation Mediators - physiology | Bacterial Proteins - antagonists & inhibitors | NF-kappa B - antagonists & inhibitors | Cystic Fibrosis - microbiology | CpG Islands - physiology | Pseudomonas Infections - microbiology | Antigens, Differentiation - physiology | Adaptor Proteins, Signal Transducing | Bacterial Proteins - pharmacology | NF-kappa B - biosynthesis | Lipopolysaccharides - pharmacology | Antigens, Differentiation - genetics | Oligodeoxyribonucleotides - pharmacology | Oligopeptides - pharmacology | Receptors, Immunologic - genetics | Inflammation Mediators - agonists | Respiratory Mucosa - pathology | Intercellular Adhesion Molecule-1 - biosynthesis | Receptors, Cell Surface - biosynthesis | Cell Line | Oligopeptides - antagonists & inhibitors | Interleukin-8 - biosynthesis | Membrane Glycoproteins - pharmacology | Membrane Glycoproteins - agonists | Receptors, Cell Surface - agonists | Interleukin-8 - antagonists & inhibitors | Myeloid Differentiation Factor 88 | Pseudomonas Infections - immunology | NF-kappa B - genetics | Lipoproteins - pharmacology | Pseudomonas Infections - pathology | Interleukin-6 - biosynthesis | Respiratory Mucosa - metabolism | Receptors, Interleukin-1 | Lipopeptides
Journal Article