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1. Full Text Human monocyte subsets are transcriptionally and functionally altered in aging in response to pattern recognition receptor agonists
by Metcalf, Talibah U and Wilkinson, Peter A and Cameron, Mark J and Ghneim, Khader and Chiang, Cindy and Wertheimer, Anne M and Hiscott, John B and Nikolich-Zugich, Janko and Haddad, Elias K
The Journal of immunology (1950), ISSN 0022-1767, 08/2017, Volume 199, Issue 4, pp. 1405 - 1417
Life Sciences & Biomedicine | Immunology | Science & Technology | Interferons - biosynthesis | Humans | Middle Aged | Male | Gene Expression Profiling | Monocytes - immunology | Interferons - immunology | Lipopolysaccharide Receptors - analysis | Young Adult | Receptors, Pattern Recognition - metabolism | Toll-Like Receptor 8 - immunology | Aging - immunology | Receptors, IgG - analysis | Toll-Like Receptor 7 - immunology | Aged, 80 and over | Receptors, Pattern Recognition - agonists | Toll-Like Receptor 4 - agonists | Adult | Female | Transcription, Genetic | Monocytes - classification | Monocytes - physiology | Cytokines - genetics | Cytokines - immunology | Toll-Like Receptor 8 - agonists | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - metabolism | GPI-Linked Proteins - analysis | Toll-Like Receptor 4 - immunology | Immunity, Innate | Toll-Like Receptor 4 - metabolism | Receptors, Pattern Recognition - genetics | Aged | Cytokines - biosynthesis | Toll-Like Receptor 8 - metabolism | Transcription | CX3CR1 protein | Infections | Vaccines | CD14 antigen | Immunity | Impact analysis | Receptors | Biological effects | Peripheral blood | Toll-like receptors | CCL20 protein | Aging | Immune system | Antigen presentation | Immunization | Immune response | TLR7 protein | Pattern recognition | TLR4 protein | IL-1β | Biological activity | Signaling | Monocytes | CD16 antigen | γ-Interferon | Interferon | Adults | Retinoic acid | Alternations | Index Medicus | Abridged Index Medicus
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2. Full Text Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: A novel paradigm for receptor cooperativity
by Rallabhandi, Prasad and Nhu, Quan M and Toshchakov, Vladimir Y and Piao, Wenji and Medvedev, Andrei E and Hollenberg, Morley D and Fasano, Alessio and Vogel, Stefanie N
The Journal of biological chemistry, ISSN 0021-9258, 09/2008, Volume 283, Issue 36, pp. 24314 - 24325
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Humans | Adaptor Proteins, Vesicular Transport - genetics | Immunity, Innate - genetics | NF-kappa B - immunology | Signal Transduction - immunology | Receptor, PAR-2 - immunology | Myeloid Differentiation Factor 88 - immunology | Adaptor Proteins, Signal Transducing - immunology | Toll-Like Receptor 4 - agonists | Cytokines - genetics | Cytokines - immunology | Receptor, PAR-2 - genetics | Cell Line | Immunity, Innate - drug effects | Receptors, Interleukin - immunology | Oligopeptides - immunology | Myeloid Differentiation Factor 88 - genetics | Macrophages, Peritoneal - immunology | Toll-Like Receptor 4 - genetics | Inflammation - immunology | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Adaptor Proteins, Vesicular Transport - immunology | Receptors, Interleukin - genetics | Mice, Knockout | Animals | NF-kappa B - genetics | Signal Transduction - drug effects | Adaptor Proteins, Signal Transducing - genetics | Lipopolysaccharides - pharmacology | Receptor, PAR-2 - agonists | Inflammation - genetics | Mice | Oligopeptides - pharmacology | Genes, Dominant - genetics | Genes, Dominant - immunology | Index Medicus
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3. Full Text TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors
by Jeroen van Bergenhenegouwen and Theo S. Plantinga and Leo A. B. Joosten and Mihai G. Netea and Gert Folkerts and Aletta D. Kraneveld and Johan Garssen and Arjan P. Vos
Journal of leukocyte biology, ISSN 0741-5400, 11/2013, Volume 94, Issue 5, pp. 885 - 902
TLR2 function | MAMP | toll like receptor | pattern recognition receptor | DAMP | Toll like receptor | Pattern recognition receptor | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | Integrins - physiology | Lipopolysaccharide Receptors - physiology | Receptors, Immunologic - physiology | Toll-Like Receptor 2 - antagonists & inhibitors | Humans | Lectins - physiology | Protein Multimerization | Receptors, Pattern Recognition - physiology | Teichoic Acids | Receptors, CXCR4 - physiology | Animals | Receptors, Scavenger - physiology | Toll-Like Receptor 2 - physiology | Membrane Microdomains - physiology | Polymorphism, Single Nucleotide | Inflammation Mediators - physiology | Toll-Like Receptor 2 - chemistry | Lipopolysaccharides - physiology | Index Medicus
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4. Full Text Inflammatory caspases are innate immune receptors for intracellular LPS
by Shi, Jianjin and Shi, Jianjin and Zhao, Yue and Zhao, Yue and Wang, Yupeng and Wang, Yupeng and Gao, Wenqing and Gao, Wenqing and Ding, Jingjin and Ding, Jingjin and Li, Peng and Li, Peng and Hu, Liyan and Hu, Liyan and Shao, Feng and Shao, Feng
Nature (London), ISSN 0028-0836, 2014, Volume 514, Issue 7521, pp. 187 - 192
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Surface Plasmon Resonance | Epithelial Cells - metabolism | Caspases - immunology | Humans | Lipopolysaccharides - metabolism | Substrate Specificity | Caspases, Initiator - genetics | Genetic Complementation Test | Lipopolysaccharides - immunology | Caspases - metabolism | Caspases, Initiator - metabolism | Protein Multimerization - genetics | Cell Death - drug effects | Caspases - chemistry | Epithelial Cells - cytology | Caspases, Initiator - immunology | Lipid A - metabolism | Caspases - genetics | Cells, Cultured | Rhodobacter sphaeroides - chemistry | Mutant Proteins - metabolism | Keratinocytes - cytology | Macrophages - cytology | Enzyme Activation - drug effects | Immunity, Innate | Necrosis - chemically induced | Macrophages - metabolism | Animals | Rhodobacter sphaeroides - immunology | Keratinocytes - metabolism | Caspases, Initiator - chemistry | Mutant Proteins - chemistry | Lipopolysaccharides - pharmacology | Protein Binding | Macrophages - drug effects | Mice | Enzyme Activation - genetics | Inflammation - enzymology | Protein Multimerization - drug effects | Lipids | Septic shock | Immune response | Health aspects | Analysis | Proteins | Salmonella | Bacterial infections | E coli | Bacteria | Cytotoxicity | Mutation | Apoptosis | Index Medicus
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5. Full Text T-Cell-Receptor-Dependent Signal Intensity Dominantly Controls CD4+ T Cell Polarization In Vivo
by van Panhuys, Nicholas and Klauschen, Frederick and Germain, Ronald N
Immunity (Cambridge, Mass.), ISSN 1074-7613, 07/2014, Volume 41, Issue 1, pp. 63 - 74
Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Communication - immunology | Cell Polarity - immunology | Adjuvants, Immunologic - pharmacology | Dendritic Cells - immunology | Mice, Transgenic | Th2 Cells - immunology | Adoptive Transfer | Th1 Cells - immunology | Cell Differentiation - immunology | Lymphocyte Activation - immunology | Animals | Lipopolysaccharides - pharmacology | Papain - pharmacology | Calcium Signaling - immunology | Receptors, Antigen, T-Cell - immunology | Mice | Cytokines - biosynthesis | Cytokines - immunology | Flow cytometry | Genotype & phenotype | Statistical analysis | Peptides | Lymphocytes | Ligands | T cell receptors | Statistical methods | Software | Index Medicus
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6. Full Text Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors
by Cros, Jérôme and Cagnard, Nicolas and Woollard, Kevin and Patey, Natacha and Zhang, Shen-Ying and Senechal, Brigitte and Puel, Anne and Biswas, Subhra K and Moshous, Despina and Picard, Capucine and Jais, Jean-Philippe and D'Cruz, David and Casanova, Jean-Laurent and Trouillet, Céline and Geissmann, Fréderic
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2010, Volume 33, Issue 3, pp. 375 - 386
Lipopolysaccharide Receptors - physiology | Reactive Oxygen Species - metabolism | Humans | GPI-Linked Proteins | Viruses - immunology | Animals | Antigen Presentation | Nucleic Acids - physiology | Receptors, IgG - analysis | Toll-Like Receptor 7 - physiology | Toll-Like Receptor 8 - physiology | Lupus Erythematosus, Systemic - immunology | Myeloid Differentiation Factor 88 - physiology | HLA-DR Antigens - analysis | Mice | Monocytes - physiology | Cytokines - biosynthesis | Studies | Flow cytometry | Cytokines | Acids | Principal components analysis | Genomes | Gene expression | Experiments | Viral infections | Index Medicus
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