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Nature immunology, ISSN 1529-2916, 03/2010, Volume 11, Issue 5, pp. 411 - 418
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific insults... 
Life Sciences & Biomedicine | Immunology | Science & Technology | RNA, Small Interfering - genetics | Endoribonucleases - genetics | Tularemia - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lipopeptides - pharmacology | Transcriptional Activation - drug effects | NADPH Oxidases - metabolism | Tularemia - genetics | Protein Splicing - genetics | Transcriptional Activation - immunology | X-Box Binding Protein 1 | Protein Splicing - drug effects | NADPH Oxidases - genetics | Stress, Physiological - drug effects | TNF Receptor-Associated Factor 6 - genetics | Transcription Factor CHOP - biosynthesis | Transcription Factors - immunology | Cytokines - genetics | Protein-Serine-Threonine Kinases - metabolism | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Macrophages - pathology | Stress, Physiological - genetics | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Macrophages - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Stress, Physiological - immunology | Endoribonucleases - immunology | Transcription Factor CHOP - genetics | NADPH Oxidases - immunology | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Macrophages - virology | Mice, Mutant Strains | Tularemia - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Cytokines - immunology | Cell Line | Francisella tularensis - immunology | Protein Splicing - immunology | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | NADPH Oxidase 2 | Regulatory Factor X Transcription Factors | Mice, Inbred C3H | Membrane Glycoproteins - genetics | Transcription Factors - metabolism | Animals | TNF Receptor-Associated Factor 6 - metabolism | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Francisella tularensis - pathogenicity | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Cell receptors | Transcription factors | Immune response | Physiological aspects | Genetic aspects | Research | Health aspects | Francisella tularensis | Index Medicus
Journal Article
Journal of neurovirology, ISSN 1538-2443, 10/2015, Volume 22, Issue 2, pp. 191 - 200
Cell-free mitochondiral DNA (mtDNA) is an immunogenic molecule associated with many inflammatory conditions. We evaluated the relationship between cell-free... 
Neurology | Neurosciences | Biomedicine | Immunology | Infectious Diseases | Pleocytosis | Mitochondrial DNA | Inflammation | Droplet digital PCR | HAND | Virology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | DNA, Mitochondrial - cerebrospinal fluid | Chemokine CCL2 - immunology | Lipopolysaccharide Receptors - cerebrospinal fluid | Humans | Memory | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Male | Antigens, CD - genetics | Learning | Neurofilament Proteins - cerebrospinal fluid | Chemokine CCL2 - cerebrospinal fluid | HIV Infections - immunology | Neurofilament Proteins - genetics | Cognitive Dysfunction - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-6 - cerebrospinal fluid | Antigens, Differentiation, Myelomonocytic - cerebrospinal fluid | HIV Infections - cerebrospinal fluid | Gene Expression | Interleukin-6 - genetics | Tumor Necrosis Factor-alpha - cerebrospinal fluid | Lipopolysaccharide Receptors - immunology | Cognitive Dysfunction - cerebrospinal fluid | Cognitive Dysfunction - pathology | Receptors, Cell Surface - immunology | Neuropsychological Tests | Antigens, CD - cerebrospinal fluid | HIV Infections - complications | Interleukin-6 - immunology | Receptors, Cell Surface - genetics | Antigens, CD - immunology | HIV-1 - physiology | HIV Infections - pathology | Chemokine CXCL10 - immunology | Adult | Female | Neopterin - immunology | Cognitive Dysfunction - complications | Neurofilament Proteins - immunology | Executive Function | Antigens, Differentiation, Myelomonocytic - immunology | Severity of Illness Index | Chemokine CXCL10 - cerebrospinal fluid | Neopterin - cerebrospinal fluid | Cross-Sectional Studies | Chemokine CCL2 - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Chemokine CXCL10 - genetics | Lipopolysaccharide Receptors - genetics | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 09/2008, Volume 283, Issue 36, pp. 24748 - 24759
...), have been shown to inhibit signaling induced by bacterial lipopeptide or lipopolysaccharide (LPS), yet the mechanisms responsible for the inhibition of Toll-like receptor... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Phosphatidylcholines - immunology | Reactive Oxygen Species - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lymphocyte Antigen 96 - metabolism | Humans | Tumor Necrosis Factor-alpha - genetics | Macrophages, Peritoneal - cytology | Flagellin - pharmacology | Lymphocyte Antigen 96 - agonists | Oxidation-Reduction - drug effects | Tumor Necrosis Factor-alpha - immunology | Toll-Like Receptor 4 - agonists | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Carrier Proteins - immunology | Guanosine - analogs & derivatives | Poly I-C - pharmacology | Macrophages, Peritoneal - immunology | Toll-Like Receptor 4 - genetics | Lipopolysaccharide Receptors - immunology | Toll-Like Receptor 4 - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | I-kappa B Kinase - immunology | Mice | Mice, Inbred BALB C | Macrophages, Peritoneal - metabolism | Oligodeoxyribonucleotides - pharmacology | Immunologic Factors - pharmacology | Lymphocyte Antigen 96 - immunology | Tumor Necrosis Factor-alpha - metabolism | Toll-Like Receptor 2 - agonists | Acute-Phase Proteins - genetics | Lipopolysaccharide Receptors - metabolism | Lymphocyte Antigen 96 - genetics | Carrier Proteins - agonists | I-kappa B Kinase - metabolism | Reactive Oxygen Species - immunology | Female | Membrane Glycoproteins - immunology | Cell Line | Acute-Phase Proteins - metabolism | Phosphatidylcholines - pharmacology | Membrane Glycoproteins - agonists | p38 Mitogen-Activated Protein Kinases - genetics | I-kappa B Kinase - genetics | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Phosphatidylcholines - genetics | Animals | Carrier Proteins - metabolism | RNA - pharmacology | Guanosine - pharmacology | Lipopolysaccharide Receptors - genetics | Signal Transduction - physiology | Acute-Phase Proteins - agonists | Acute-Phase Proteins - immunology | Index Medicus | Lipids and Lipoproteins | Metabolism, Regulation, and Signaling
Journal Article
Nature (London), ISSN 1476-4687, 07/2015, Volume 523, Issue 7560, pp. 308 - 312
Journal Article
Human Immunology, ISSN 0198-8859, 2014, Volume 75, Issue 8, pp. 808 - 815
.... Initial recognition of H. pylori involves Toll-like receptors (TLRs), central molecules in the host inflammatory response... 
Allergy and Immunology | Toll-like receptors | Helicobacter pylori | Stomach neoplasms | Polymorphism | Life Sciences & Biomedicine | Immunology | Science & Technology | Toll-Like Receptor 2 - genetics | Humans | Middle Aged | Receptors, Interleukin-1 - genetics | Helicobacter Infections - complications | Male | Acute-Phase Proteins - genetics | Case-Control Studies | Lymphocyte Antigen 96 - genetics | China | Female | Membrane Glycoproteins - immunology | Carrier Proteins - immunology | Stomach Neoplasms - genetics | Gene Expression | Genetic Predisposition to Disease | Stomach Neoplasms - complications | Signal Transduction | Receptors, Interleukin-1 - immunology | Toll-Like Receptor 4 - genetics | Lipopolysaccharide Receptors - immunology | Helicobacter Infections - immunology | Toll-Like Receptor 4 - immunology | Helicobacter Infections - genetics | Membrane Glycoproteins - genetics | Polymorphism, Genetic | Stomach Neoplasms - immunology | Stomach Neoplasms - microbiology | Carrier Proteins - genetics | Lipopolysaccharide Receptors - genetics | Toll-Like Receptor 2 - immunology | Aged | Helicobacter pylori - physiology | Lymphocyte Antigen 96 - immunology | Acute-Phase Proteins - immunology | Helicobacter Infections - microbiology | Helicobacter infections | Genetic aspects | Health aspects | Stomach cancer | Genetic polymorphisms | Cancer | Index Medicus
Journal Article
Journal Article
Arthritis research & therapy, ISSN 1478-6354, 2013, Volume 15, Issue 5, pp. R170 - R170
...). This suggests that IL-29 has an important role in synovial inflammation. Toll-like receptors (TLRs) also activate RA-FLS to produce inflammatory mediators including tumor necrosis factor... 
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Interleukin-8 - genetics | Toll-Like Receptor 2 - agonists | Toll-Like Receptor 2 - genetics | Gene Expression - drug effects | Humans | Synovial Membrane - pathology | Interleukins - metabolism | Arthritis, Rheumatoid - metabolism | Interleukins - genetics | Flow Cytometry | Toll-Like Receptor 4 - agonists | Toll-Like Receptor 3 - genetics | Interleukin-8 - metabolism | Interleukins - pharmacology | Receptors, Cytokine - metabolism | Interleukin-6 - metabolism | Receptors, Cytokine - genetics | Fibroblasts - metabolism | Cell Line | Poly I-C - pharmacology | Enzyme-Linked Immunosorbent Assay | Interleukin-6 - genetics | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 3 - agonists | Toll-Like Receptor 2 - metabolism | Fibroblasts - pathology | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 3 - metabolism | Synovial Membrane - metabolism | Toll-Like Receptor 4 - metabolism | Arthritis, Rheumatoid - pathology | Receptors, Interleukin-10 - metabolism | Arthritis, Rheumatoid - genetics | Fibroblasts - drug effects | Lipopolysaccharides - pharmacology | Peptidoglycan - pharmacology | Receptors, Interleukin-10 - genetics | Enzymes | Immune response | Tumor necrosis factor | Rheumatoid arthritis | Toll-like receptors | Inflammation | Mitogens | Immunity | Enzyme-linked immunosorbent assay | Index Medicus
Journal Article
Journal of neurovirology, ISSN 1538-2443, 12/2016, Volume 23, Issue 2, pp. 283 - 289
Cell-free mitochondrial DNA (mtDNA) is a highly immunogenic molecule that is associated with several inflammatory conditions and with neurocognitive impairment... 
ddPCR | Neurology | Neurosciences | Biomedicine | Immunology | mtDNA | Neurodegeneration | Infectious Diseases | Inflammation | Neurocognitive performance | Virology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | DNA, Mitochondrial - cerebrospinal fluid | Interleukin-8 - genetics | Humans | Middle Aged | Tumor Necrosis Factor-alpha - blood | Tumor Necrosis Factor-alpha - genetics | Male | RNA, Viral - blood | Cognition | Antigens, CD - genetics | HIV - drug effects | Chemokine CCL2 - cerebrospinal fluid | HIV Infections - diagnosis | Adult | Female | Cognitive Dysfunction - diagnosis | Retrospective Studies | Cognitive Dysfunction - complications | Interleukin-8 - blood | Cognitive Dysfunction - drug therapy | HIV Infections - cerebrospinal fluid | Chemokine CXCL10 - blood | Gene Expression | Antiviral Agents - therapeutic use | Chemokine CCL2 - genetics | Receptors, Cell Surface - blood | Biomarkers - blood | Cognitive Dysfunction - cerebrospinal fluid | HIV - pathogenicity | Antigens, Differentiation, Myelomonocytic - genetics | Disease Progression | HIV - growth & development | Lipopolysaccharide Receptors - blood | Neuropsychological Tests | Antigens, CD - blood | Antigens, Differentiation, Myelomonocytic - blood | Chemokine CXCL10 - genetics | HIV Infections - complications | Lipopolysaccharide Receptors - genetics | HIV Infections - drug therapy | Biomarkers - cerebrospinal fluid | Receptors, Cell Surface - genetics | Index Medicus | neurocognitive performance | neurodegeneration | inflammation
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 523 - 530.e9
Background There is evidence that gene expression of innate immunity receptors is upregulated by farming-related exposures... 
Allergy and Immunology | nutrition | childhood | prenatal | farming | farm milk | Toll-like receptors | Innate immunity | CD14 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | RNA, Messenger - immunology | Prospective Studies | Humans | Immunity, Innate - genetics | Prenatal Exposure Delayed Effects - prevention & control | Infant | Male | Maternal Exposure | RNA, Messenger - biosynthesis | Rural Population | Fetal Blood - chemistry | Gene Expression - immunology | Hypersensitivity, Immediate - immunology | Adult | Female | Surveys and Questionnaires | Agriculture | Milk - immunology | Polymorphism, Single Nucleotide - immunology | Fetal Blood - immunology | Cats | Toll-Like Receptors - immunology | Hypersensitivity, Immediate - genetics | Lipopolysaccharide Receptors - immunology | Hypersensitivity, Immediate - prevention & control | Pregnancy | Prenatal Exposure Delayed Effects - genetics | Immunity, Innate - immunology | Animals | Prenatal Exposure Delayed Effects - immunology | Toll-Like Receptors - genetics | Lipopolysaccharide Receptors - genetics | Polymorphism, Single Nucleotide - genetics | Medical colleges | Pregnant women | Analysis | Genes | Environmental health | Genetic research | Respiratory tract diseases | Gene expression | Allergic reaction | Biometry | Public health | Disease | Rural areas | Farm buildings | Allergies | Asthma | Hay fever | Womens health | Questionnaires | Age | Immune system | Farming | Index Medicus | Abridged Index Medicus | Neonates | Inventories | TLR7 protein | TLR5 protein | Hypersensitivity | Single-nucleotide polymorphism | Regression analysis | TLR4 protein | CD14 antigen | Gene polymorphism | Immunity | Rural environments | TLR9 protein | Cord blood | Farms | Pasture | Prenatal experience | Food | Milk | Prenatal Exposure Delayed Effects | Antigens, CD14 | Hypersensitivity, Immediate | Life Sciences | Toll-Like Receptors | Pulmonology and respiratory tract | Gene Expression | Immunity, Innate | Human health and pathology | Polymorphism, Single Nucleotide | RNA, Messenger | Fetal Blood
Journal Article