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Journal of Biological Chemistry, ISSN 0021-9258, 09/2007, Volume 282, Issue 36, pp. 26014 - 26025
.... The total fraction of Mycobacterium bovis BCG LM was shown both to induce macrophage activation and pro-inflammatory cytokines through Toll-like receptor 2 (TLR2... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Mannose-Binding Lectins - metabolism | Mycobacterium bovis - immunology | Toll-Like Receptor 2 - agonists | Membrane Glycoproteins - metabolism | Humans | Lectins, C-Type - immunology | Mycobacterium tuberculosis - immunology | Lipopolysaccharides - metabolism | Cell Adhesion Molecules - immunology | Lipopolysaccharides - immunology | Lectins, C-Type - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Macrophages - secretion | Toll-Like Receptor 1 - agonists | Myeloid Differentiation Factor 88 - immunology | Tumor Necrosis Factor-alpha - immunology | Toll-Like Receptor 4 - agonists | Interleukin-12 Subunit p40 - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Acylation | Cell Line | Nitric Oxide - immunology | Immunity, Innate - drug effects | Macrophage Activation - immunology | Receptors, Interleukin-1 - immunology | Tumor Necrosis Factor-alpha - secretion | Receptors, Cell Surface - metabolism | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Cell Adhesion Molecules - metabolism | Receptors, Cell Surface - immunology | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Nitric Oxide - secretion | Animals | Mannose-Binding Lectins - immunology | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Toll-Like Receptor 1 - immunology | Macrophage Activation - drug effects | Myeloid Differentiation Factor 88 - metabolism | Index Medicus | Toll-Like Receptor 1 | Toll-Like Receptor 2 | Toll-Like Receptor 4 | Cell Adhesion Molecules | Receptors, Cell Surface | Macrophages | Lipopolysaccharides | Life Sciences | Immunology | Membrane Glycoproteins | Mannose-Binding Lectins | Mycobacterium bovis | Signal Transduction | Lectins, C-Type | Inflammation | Myeloid Differentiation Factor 88 | Nitric Oxide | Tumor Necrosis Factor-alpha | Immunity, Natural | Macrophage Activation | Mycobacterium tuberculosis | Receptors, Interleukin-1 | Interleukin-12 Subunit p40
Journal Article
Nature immunology, ISSN 1529-2916, 03/2010, Volume 11, Issue 5, pp. 411 - 418
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific insults... 
Life Sciences & Biomedicine | Immunology | Science & Technology | RNA, Small Interfering - genetics | Endoribonucleases - genetics | Tularemia - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lipopeptides - pharmacology | Transcriptional Activation - drug effects | NADPH Oxidases - metabolism | Tularemia - genetics | Protein Splicing - genetics | Transcriptional Activation - immunology | X-Box Binding Protein 1 | Protein Splicing - drug effects | NADPH Oxidases - genetics | Stress, Physiological - drug effects | TNF Receptor-Associated Factor 6 - genetics | Transcription Factor CHOP - biosynthesis | Transcription Factors - immunology | Cytokines - genetics | Protein-Serine-Threonine Kinases - metabolism | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Macrophages - pathology | Stress, Physiological - genetics | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Macrophages - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Stress, Physiological - immunology | Endoribonucleases - immunology | Transcription Factor CHOP - genetics | NADPH Oxidases - immunology | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Macrophages - virology | Mice, Mutant Strains | Tularemia - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Cytokines - immunology | Cell Line | Francisella tularensis - immunology | Protein Splicing - immunology | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | NADPH Oxidase 2 | Regulatory Factor X Transcription Factors | Mice, Inbred C3H | Membrane Glycoproteins - genetics | Transcription Factors - metabolism | Animals | TNF Receptor-Associated Factor 6 - metabolism | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Francisella tularensis - pathogenicity | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Cell receptors | Transcription factors | Immune response | Physiological aspects | Genetic aspects | Research | Health aspects | Francisella tularensis | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 04/2011, Volume 472, Issue 7343, pp. 361 - 365
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Capsid - chemistry | Receptors, Pattern Recognition - immunology | Humans | Ubiquitin - metabolism | NF-kappa B - metabolism | Lipopolysaccharides - immunology | Transcription Factor AP-1 - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Ubiquitin-Protein Ligases - immunology | HIV-1 - chemistry | HEK293 Cells | Carrier Proteins - immunology | Cell Line | Retroviridae - chemistry | Ubiquitin-Protein Ligases - metabolism | Retroviridae - immunology | MAP Kinase Kinase Kinases - metabolism | Transcription Factors - metabolism | Capsid - immunology | Carrier Proteins - genetics | Immunity, Innate - immunology | HIV-1 - immunology | Carrier Proteins - metabolism | Signal Transduction - drug effects | Ubiquitin-Conjugating Enzymes - metabolism | Lipopolysaccharides - pharmacology | Protein Binding | Enzyme Activation | Ubiquitin-Protein Ligases - genetics | Signal transduction | Efficiency | RNA polymerase | Pattern recognition | Kinases | Evacuations & rescues | Immune system | Index Medicus | HIV-1/immunology | Capsid/immunology | Life Sciences | MAP Kinase Kinase Kinases/metabolism | Carrier Proteins/immunology | Immunology | Transcription Factors/metabolism | Capsid/chemistry | HIV-1/chemistry | Ubiquitin/metabolism | Receptors, Pattern Recognition/immunology | Retroviridae/chemistry | Ubiquitin-Protein Ligases/immunology | Ubiquitin-Conjugating Enzymes/metabolism | HumansImmunity, Innate/immunology | Lipopolysaccharides/pharmacology | Signal Transduction/drug effects | Retroviridae/immunology | Transcription Factor AP-1/metabolism | Lipopolysaccharides/immunology | Ubiquitin-Protein Ligases/metabolism | Carrier Proteins/genetics | Signal Transduction/immunology | NF-kappa B/metabolism | Ubiquitin-Protein Ligases/genetics | Carrier Proteins/metabolism | Receptors, Pattern Recognition/metabolism
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 523 - 530.e9
Background There is evidence that gene expression of innate immunity receptors is upregulated by farming-related exposures... 
Allergy and Immunology | nutrition | childhood | prenatal | farming | farm milk | Toll-like receptors | Innate immunity | CD14 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | RNA, Messenger - immunology | Prospective Studies | Humans | Immunity, Innate - genetics | Prenatal Exposure Delayed Effects - prevention & control | Infant | Male | Maternal Exposure | RNA, Messenger - biosynthesis | Rural Population | Fetal Blood - chemistry | Gene Expression - immunology | Hypersensitivity, Immediate - immunology | Adult | Female | Surveys and Questionnaires | Agriculture | Milk - immunology | Polymorphism, Single Nucleotide - immunology | Fetal Blood - immunology | Cats | Toll-Like Receptors - immunology | Hypersensitivity, Immediate - genetics | Lipopolysaccharide Receptors - immunology | Hypersensitivity, Immediate - prevention & control | Pregnancy | Prenatal Exposure Delayed Effects - genetics | Immunity, Innate - immunology | Animals | Prenatal Exposure Delayed Effects - immunology | Toll-Like Receptors - genetics | Lipopolysaccharide Receptors - genetics | Polymorphism, Single Nucleotide - genetics | Medical colleges | Pregnant women | Analysis | Genes | Environmental health | Genetic research | Respiratory tract diseases | Gene expression | Allergic reaction | Biometry | Public health | Disease | Rural areas | Farm buildings | Allergies | Asthma | Hay fever | Womens health | Questionnaires | Age | Immune system | Farming | Index Medicus | Abridged Index Medicus | Neonates | Inventories | TLR7 protein | TLR5 protein | Hypersensitivity | Single-nucleotide polymorphism | Regression analysis | TLR4 protein | CD14 antigen | Gene polymorphism | Immunity | Rural environments | TLR9 protein | Cord blood | Farms | Pasture | Prenatal experience | Food | Milk | Prenatal Exposure Delayed Effects | Antigens, CD14 | Hypersensitivity, Immediate | Life Sciences | Toll-Like Receptors | Pulmonology and respiratory tract | Gene Expression | Immunity, Innate | Human health and pathology | Polymorphism, Single Nucleotide | RNA, Messenger | Fetal Blood
Journal Article
Nature immunology, ISSN 1529-2916, 09/2014, Volume 15, Issue 10, pp. 920 - 928
Journal Article
Journal of neurovirology, ISSN 1538-2443, 10/2015, Volume 22, Issue 2, pp. 191 - 200
Cell-free mitochondiral DNA (mtDNA) is an immunogenic molecule associated with many inflammatory conditions. We evaluated the relationship between cell-free... 
Neurology | Neurosciences | Biomedicine | Immunology | Infectious Diseases | Pleocytosis | Mitochondrial DNA | Inflammation | Droplet digital PCR | HAND | Virology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | DNA, Mitochondrial - cerebrospinal fluid | Chemokine CCL2 - immunology | Lipopolysaccharide Receptors - cerebrospinal fluid | Humans | Memory | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Male | Antigens, CD - genetics | Learning | Neurofilament Proteins - cerebrospinal fluid | Chemokine CCL2 - cerebrospinal fluid | HIV Infections - immunology | Neurofilament Proteins - genetics | Cognitive Dysfunction - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-6 - cerebrospinal fluid | Antigens, Differentiation, Myelomonocytic - cerebrospinal fluid | HIV Infections - cerebrospinal fluid | Gene Expression | Interleukin-6 - genetics | Tumor Necrosis Factor-alpha - cerebrospinal fluid | Lipopolysaccharide Receptors - immunology | Cognitive Dysfunction - cerebrospinal fluid | Cognitive Dysfunction - pathology | Receptors, Cell Surface - immunology | Neuropsychological Tests | Antigens, CD - cerebrospinal fluid | HIV Infections - complications | Interleukin-6 - immunology | Receptors, Cell Surface - genetics | Antigens, CD - immunology | HIV-1 - physiology | HIV Infections - pathology | Chemokine CXCL10 - immunology | Adult | Female | Neopterin - immunology | Cognitive Dysfunction - complications | Neurofilament Proteins - immunology | Executive Function | Antigens, Differentiation, Myelomonocytic - immunology | Severity of Illness Index | Chemokine CXCL10 - cerebrospinal fluid | Neopterin - cerebrospinal fluid | Cross-Sectional Studies | Chemokine CCL2 - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Chemokine CXCL10 - genetics | Lipopolysaccharide Receptors - genetics | Index Medicus
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
PloS one, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e15041 - e15041
Newborns and young infants suffer increased infectious morbidity and mortality as compared to older children and adults. Morbidity and mortality due to... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Leukocytes, Mononuclear - metabolism | Toll-Like Receptor 2 - agonists | Age Factors | Lipopeptides - pharmacology | Dendritic Cells - immunology | Humans | Middle Aged | Child, Preschool | Infant | Toll-Like Receptor 9 - agonists | Toll-Like Receptor 9 - immunology | Young Adult | Toll-Like Receptor 8 - immunology | Leukocytes, Mononuclear - immunology | Toll-Like Receptor 7 - immunology | Toll-Like Receptor 4 - agonists | Adult | Dendritic Cells - drug effects | Dendritic Cells - metabolism | Infant, Newborn | Cytokines - immunology | Toll-Like Receptor 8 - agonists | Toll-Like Receptor 7 - agonists | Antigen-Presenting Cells - metabolism | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Antigen-Presenting Cells - drug effects | Toll-Like Receptors - immunology | Toll-Like Receptor 4 - immunology | Antigen-Presenting Cells - immunology | Toll-Like Receptors - agonists | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Oligodeoxyribonucleotides - pharmacology | Cohort Studies | Infants (Newborn) | Cytokines | Mortality | Vaccines | B cells | Comparative analysis | Health aspects | Neonates | Flow cytometry | Pediatrics | Helper cells | Leukocytes (mononuclear) | Stimulation | Interleukin 23 | Infants | Lymphocytes T | Infections | Ontogeny | Birth | Immunity | Interleukin 6 | Proteins | Immunology | Newborn babies | Toll-like receptors | Children | Age | Immune system | Medical research | Antigens | Immune response | Fetuses | Interleukin 12 | T cell receptors | Tumor necrosis factor-α | Morbidity | Childbirth & labor | Herpes viruses | γ-Interferon | Interleukin 10 | Interferon | Adults | Human behavior | Index Medicus
Journal Article