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1998, Lung biology in health and disease, ISBN 9780824701673, Volume 120., xviii, 493
Five-Lipoxygenase Products in Asthma offers an authoritative examination of the biochemistry, basic pharmacology, and clinical pharmacology of the leukotrienes... 
Chemotherapy | Pathophysiology | Metabolism | Leukotrienes | Asthma
Book
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2012, Volume 47, Issue 1, pp. 111 - 124
Balanced modulation of several targets is one of the current strategies for the treatment of multi-factorial diseases. Based on the knowledge of inflammation... 
Multi-target drugs | Benzo/benzisothiazolidinones | Inflammation | Lipoxygenase inhibitors | COX-1/2 inhibitors | Fragment-based drug design | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | MECHANISM | CRYSTAL-STRUCTURE | LIPOXYGENASES | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | COX-2 INHIBITORS | DUAL INHIBITORS | DERIVATIVES | ANTIMICROBIAL ACTIVITY | LIGAND DESIGN | Thiazolidines - chemical synthesis | Thiazolidines - metabolism | Male | Structure-Activity Relationship | Anti-Inflammatory Agents - metabolism | Lipoxygenase - metabolism | Lipoxygenase Inhibitors - chemical synthesis | Lipoxygenase Inhibitors - chemistry | Drug Design | Cyclooxygenase 1 - chemistry | Female | Thiazolidines - pharmacology | Thiazolidines - chemistry | Catalytic Domain | Cyclooxygenase Inhibitors - metabolism | Anti-Inflammatory Agents - pharmacology | Cyclooxygenase 2 - chemistry | Models, Molecular | Cyclooxygenase Inhibitors - chemistry | Edema - drug therapy | Lipoxygenase - chemistry | Cyclooxygenase Inhibitors - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Cyclooxygenase 2 - metabolism | Cyclooxygenase Inhibitors - chemical synthesis | Anti-Inflammatory Agents - chemical synthesis | Lipoxygenase Inhibitors - metabolism | Mice | Cyclooxygenase 1 - metabolism | Edema - chemically induced | Lipoxygenase Inhibitors - pharmacology | COX-2 inhibitors | Enzymes | Index Medicus
Journal Article
Advances in prostaglandin, thromboxane, and leukotriene research, ISSN 0732-8141, 1982
Journal
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 122, pp. 786 - 801
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2011, Volume 46, Issue 1, pp. 191 - 200
A series of novel acrylic acid derivatives bearing at the 3 position thienyl, furfuryl and 3,5-ditert-butyl-4-hydroxyphenyl substituents have been designed,... 
Substituted acrylic acids | LOX | COX-1 | Cyclooxygenase inhibitors | Lipoxygenase inhibitors | Anti-inflammatory agents | Antioxidant agents | CHEMISTRY, MEDICINAL | ESTER PRODRUGS | DI-TERT-BUTYLPHENOLS | 2,6-DI-TERT-BUTYLPHENOL | IN-VIVO EVALUATIONS | ANALGESIC AGENTS | BIOLOGICAL EVALUATION | 7-TERT-BUTYL-2,3-DIHYDRO-3,3-DIMETHYLBENZOFURAN DERIVATIVES | DUAL INHIBITORS | CYCLOOXYGENASE-2/5-LIPOXYGENASE INHIBITORS | 5-LIPOXYGENASE | Free Radical Scavengers - pharmacology | Acrylates - therapeutic use | Antioxidants - chemistry | Free Radical Scavengers - chemistry | Male | Lipoxygenase - metabolism | Lipoxygenase Inhibitors - chemical synthesis | Lipoxygenase Inhibitors - chemistry | Inflammation - drug therapy | Acrylates - pharmacology | Soybeans - enzymology | Drug Design | Anti-Inflammatory Agents - therapeutic use | Cyclooxygenase 1 - chemistry | Free Radical Scavengers - chemical synthesis | Acrylates - chemical synthesis | Female | Free Radical Scavengers - therapeutic use | Binding Sites | Acrylates - chemistry | Anti-Inflammatory Agents - pharmacology | Lipoxygenase Inhibitors - therapeutic use | Models, Molecular | Rats | Cyclooxygenase Inhibitors - chemistry | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Lipoxygenase - chemistry | Cyclooxygenase Inhibitors - pharmacology | Antioxidants - therapeutic use | Animals | Anti-Inflammatory Agents - chemistry | Cyclooxygenase Inhibitors - chemical synthesis | Protein Conformation | Anti-Inflammatory Agents - chemical synthesis | Cyclooxygenase 1 - metabolism | Lipoxygenase Inhibitors - pharmacology | Cyclooxygenase Inhibitors - therapeutic use | Antioxidants | Boats and boating | Anti-inflammatory drugs | Analysis | Acrylic acid | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article