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1. Full Text Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight
by Anderberg, Rozita H and Richard, Jennifer E and Eerola, Kim and López-Ferreras, Lorena and Banke, Elin and Hansson, Caroline and Nissbrandt, Hans and Berqquist, Filip and Gribble, Fiona M and Reimann, Frank and Wernstedt Asterholm, Ingrid and Lamy, Christophe M and Skibicka, Karolina P and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Physiology and Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi and Sahlgrenska Academy and Sahlgrenska akademin and Institute of Neuroscience and Physiology, Department of Pharmacology and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi
Diabetes (New York, N.Y.), ISSN 0012-1797, 04/2017, Volume 66, Issue 4, p. 1062
Anorexia | Receptor, Serotonin, 5-HT2C - metabolism | Body Weight - drug effects | Male | Weight Loss - drug effects | Pyrrolidines - pharmacology | Glucagon-Like Peptide-1 Receptor - metabolism | Liraglutide - pharmacology | Glucagon-Like Peptide-1 Receptor - drug effects | Indoles - pharmacology | Receptor, Serotonin, 5-HT2A - drug effects | Fenclonine - pharmacology | Receptor, Serotonin, 5-HT2C - drug effects | Glucagon-Like Peptide 1 - pharmacology | Appetite - drug effects | Rats | Serotonin Antagonists - pharmacology | Rats, Sprague-Dawley | Feeding Behavior - drug effects | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Animals | Dorsal Raphe Nucleus - metabolism | Aminopyridines - pharmacology | Serotonin - metabolism | Venoms - pharmacology | Receptor, Serotonin, 5-HT2A - metabolism | Care and treatment | Control | Brain diseases, Metabolic | Glucagon | Serotonin | Research | Health aspects | Weight gain | Appetite | Hormones | Peptides | Energy | Weight | Weight Loss/drug effects | Neurosciences | Glucagon-Like Peptide 1/pharmacology | 5-HT2C/drug effects/metabolism | Pyrrolidines/pharmacology | Indoles/pharmacology | Fenclonine/pharmacology | Sprague-Dawley | Dorsal Raphe Nucleus/metabolism | Peptides/pharmacology | Feeding Behavior/drug effects | Hypoglycemic Agents/pharmacology | Neurovetenskaper | Body Weight/drug effects | 5-HT2A/drug effects/metabolism | Liraglutide/pharmacology | Glucagon-Like Peptide-1 Receptor/drug effects/metabolism | Aminopyridines/pharmacology | Receptor | Serotonin/metabolism | Serotonin Antagonists/pharmacology | Appetite/drug effects | Venoms/pharmacology
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2. Full Text Pharmacology of Dipeptidyl Peptidase-4 Inhibitors
: Similarities and Differences
by Baetta, Roberta and Corsini, Alberto
Drugs (New York, N.Y.), ISSN 0012-6667, 7/2011, Volume 71, Issue 11, pp. 1441 - 1467
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Drug-interactions | Sulfonylureas | Alogliptin | Sitagliptin | Linagliptin | Vildagliptin | Metformin | Alpha-glucosidase-inhibitors | Exenatide | Thiazolidinediones | Liraglutide | Saxagliptin | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Hormones. Endocrine system | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Age Factors | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Male | Treatment Outcome | Drug Approval | Molecular Targeted Therapy | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Hypoglycemic Agents - pharmacology | Diabetes Mellitus, Type 2 - physiopathology | Dipeptidyl-Peptidase IV Inhibitors - pharmacokinetics | Female | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Complications and side effects | Hypoglycemic agents | Dosage and administration | Index Medicus
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3. Update on cardiovascular effects of older and newer anti-diabetic medications
by Eleftheriadou, Ioanna and Grigoropoulou, Pinelopi and Liberopoulos, Evangelos and Liatis, Stavros and Kokkinos, Alexandros and Tentolouris, Nikolaos
Current medicinal chemistry, ISSN 0929-8673, 05/2017, Volume 25, Issue 13, pp. 1549 - 1566
Cardiovascular events | Pioglitazone | Sulfonylureas | Dipeptidyl peptidase-4 inhibitors | Glucagon-like peptide-1 receptor agonists | Metformin | Insulin | Sodium-glucose co-transporters-2 inhibitors | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Metformin - therapeutic use | Cardiovascular Diseases - drug therapy | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Pioglitazone - therapeutic use | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Cardiovascular Diseases - complications | Glucagon-Like Peptides - pharmacology | Liraglutide - pharmacology | Glucosides - therapeutic use | Benzhydryl Compounds - therapeutic use | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Insulin - pharmacology | Glucosides - pharmacology | Sodium-Glucose Transporter 2 - metabolism | Metformin - pharmacology | Pioglitazone - pharmacology | Hypoglycemic Agents - pharmacology | Liraglutide - therapeutic use | Benzhydryl Compounds - pharmacology | Glucagon-Like Peptides - therapeutic use | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Insulin - therapeutic use | Heart | Diabetes mellitus | Clinical trials | Diabetes | Safety | Diabetes mellitus (non-insulin dependent) | Heart diseases | Patients | Morbidity
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4. Full Text A Meta-Analysis of Placebo-Controlled Clinical Trials Assessing the Efficacy and Safety of Incretin-Based Medications in Patients with Type 2 Diabetes
by Fakhoury, Walid K.H and LeReun, Corinne and Wright, Donna
Pharmacology, ISSN 0031-7012, 08/2010, Volume 86, Issue 1, pp. 44 - 57
Review | Glycemic control | Diabetes | Incretin mimetics | Hypoglycemia | Dipeptyl peptidase type 4 inhibitor | Weight | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Triazoles - adverse effects | Nitriles - pharmacology | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Glycated Hemoglobin A - metabolism | Humans | Pyrrolidines - adverse effects | Pyrazines - therapeutic use | Weight Loss - drug effects | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Pyrrolidines - pharmacology | Pyrrolidines - therapeutic use | Adamantane - therapeutic use | Adult | Sitagliptin Phosphate | Drug Therapy, Combination | Hypoglycemia - chemically induced | Adamantane - adverse effects | Adamantane - analogs & derivatives | Triazoles - therapeutic use | Hypoglycemic Agents - therapeutic use | Adamantane - pharmacology | Glucagon-Like Peptide 1 - analogs & derivatives | Venoms - adverse effects | Glucagon-Like Peptide 1 - pharmacology | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Triazoles - pharmacology | Pyrazines - adverse effects | Venoms - therapeutic use | Venoms - pharmacology | Diabetes Mellitus, Type 2 - drug therapy | Glucagon-Like Peptide 1 - adverse effects | Nitriles - adverse effects | Pyrazines - pharmacology | Hypoglycemic Agents - adverse effects | Liraglutide | Peptides - adverse effects | Peptides - therapeutic use | Glucagon-Like Peptide 1 - therapeutic use | Nitriles - therapeutic use | Index Medicus
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5. Full Text Gender‐related issues in the pharmacology of new anti‐obesity drugs
by Cataldi, Mauro and Muscogiuri, Giovanna and Savastano, Silvia and Barrea, Luigi and Guida, Bruna and Taglialatela, Maurizio and Colao, Annamaria
Obesity reviews, ISSN 1467-7881, 03/2019, Volume 20, Issue 3, pp. 375 - 384
liraglutide | phentermine/topiramate | lorcaserin | naltrexone/bupropion | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Drugs | Weight reducing preparations | Obesity | Pharmacology | Drug therapy | Epidemics | Topiramate | Subpopulations | Pharmacodynamics | Bupropion | Gender | Naltrexone | Disease control | Drug dosages | Index Medicus
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6. Full Text DPP-4 Inhibitors Repress NLRP3 Inflammasome and Interleukin-1beta via GLP-1 Receptor in Macrophages Through Protein Kinase C Pathway
by Dai, Yao and Dai, Dongsheng and Wang, Xianwei and Ding, Zufeng and Mehta, Jawahar L
Cardiovascular drugs and therapy, ISSN 0920-3206, 10/2014, Volume 28, Issue 5, pp. 425 - 432
DPP-4 | PKC | Inflammation | GLP-1 | Medicine & Public Health | Cardiology | Cardiac & Cardiovascular Systems | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiovascular system | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Pyrazines - antagonists & inhibitors | Tetradecanoylphorbol Acetate - pharmacology | Toll-Like Receptor 4 - biosynthesis | Nitriles - pharmacology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Pyrrolidines - antagonists & inhibitors | Tetradecanoylphorbol Acetate - analogs & derivatives | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Inflammasomes - biosynthesis | Pyrrolidines - pharmacology | Protein Kinase C - metabolism | Interleukin-1beta - biosynthesis | Cell Culture Techniques | Nitriles - antagonists & inhibitors | Phosphorylation - drug effects | Sitagliptin Phosphate | Cyclic AMP-Dependent Protein Kinases - biosynthesis | Glucagon-Like Peptide 1 - analogs & derivatives | Carrier Proteins - biosynthesis | Glucagon-Like Peptide 1 - pharmacology | Receptors, Glucagon - metabolism | Triazoles - antagonists & inhibitors | Gene Expression Regulation - drug effects | Triazoles - pharmacology | Macrophages - metabolism | Carrier Proteins - metabolism | Glucagon-Like Peptide-1 Receptor | Signal Transduction - drug effects | Receptors, Glucagon - biosynthesis | Macrophages - drug effects | Pyrazines - pharmacology | Liraglutide | Peptides | Interleukins | Low density lipoproteins | Atherosclerosis | Macrophages | Protein kinases | Index Medicus
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7. Full Text Liraglutide in Type 2 Diabetes Mellitus: Clinical Pharmacokinetics and Pharmacodynamics
by Jacobsen, Lisbeth V and Jacobsen, Lisbeth V and Flint, Anne and Flint, Anne and Olsen, Anette K and Olsen, Anette K and Ingwersen, Steen H and Ingwersen, Steen H
Clinical pharmacokinetics, ISSN 0312-5963, 6/2016, Volume 55, Issue 6, pp. 657 - 672
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hypoglycemic Agents - therapeutic use | Hypoglycemic Agents - pharmacokinetics | Body Weight | Area Under Curve | Glucagon-Like Peptide 1 - analogs & derivatives | Humans | Blood Glucose | Renal Insufficiency - metabolism | Hypoglycemic Agents - pharmacology | Liver Failure - metabolism | Insulin - metabolism | Drug Interactions | Liraglutide - pharmacokinetics | Liraglutide - pharmacology | Injections, Subcutaneous | Lipids - blood | Liraglutide - therapeutic use | Sex Factors | Glucagon - metabolism | Diabetes Mellitus, Type 2 - drug therapy
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8. Full Text Peripheral and Central GLP-1 Receptor Populations Mediate the Anorectic Effects of Peripherally Administered GLP-1 Receptor Agonists, Liraglutide and Exendin-4
by Kanoski, Scott E and Fortin, Samantha M and Arnold, Myrtha and Grill, Harvey J and Hayes, Matthew R
Endocrinology (Philadelphia), ISSN 0013-7227, 08/2011, Volume 152, Issue 8, pp. 3103 - 3112
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: endocrinology | Biological and medical sciences | Calcitonin - pharmacology | Receptors, Glucagon - agonists | Glucagon-Like Peptide 1 - analogs & derivatives | Appetite Depressants - pharmacology | Glucagon-Like Peptide 1 - pharmacology | Body Weight - drug effects | Rats | Male | Peptide Fragments - pharmacology | Brain - physiology | Rats, Sprague-Dawley | Peptides - pharmacology | Eating - drug effects | Vagus Nerve - physiology | Animals | Glucagon-Like Peptide-1 Receptor | Venoms - pharmacology | Liraglutide | Receptors, Glucagon - physiology | Index Medicus | Abridged Index Medicus | 500 | 300 | Energy Balance-Obesity
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