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World Journal of Gastroenterology, ISSN 1007-9327, 11/2013, Volume 19, Issue 41, pp. 6969 - 6978
The 148 Isoleucine to Methionine protein variant (I148M) of patatin-like phospholipase domain-containing 3 (PNPLA3), a protein is expressed in the liver and is... 
Liver disease | Patatin-like phospholipase domain-containing 3 | Chronic hepatitis C virus hepatitis | Genetics | Hepatocellular carcinoma | Nonalcoholic fatty liver disease | Single nucleotide polymorphism | Fibrogenesis | Alcoholic liver disease | Steatosis | CHRONIC HEPATITIS-C | NONALCOHOLIC STEATOHEPATITIS | GREATER-THAN-G | B-VIRUS INFECTION | HEPATOCELLULAR-CARCINOMA | INSULIN-RESISTANCE | FATTY LIVER | DOMAIN-CONTAINING 3 | GENETIC VARIANT | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Cholangitis, Sclerosing - enzymology | Hepatitis C, Chronic - pathology | Fatty Liver - pathology | Humans | Cholangitis, Sclerosing - genetics | Fatty Liver - complications | Hepatitis B, Chronic - enzymology | Hepatitis C, Chronic - complications | Liver Cirrhosis - enzymology | Hemochromatosis - pathology | Fatty Liver, Alcoholic - genetics | Hepatitis B, Chronic - genetics | Liver Cirrhosis, Alcoholic - enzymology | Hepatitis C, Chronic - enzymology | Fatty Liver - enzymology | Non-alcoholic Fatty Liver Disease | Liver Neoplasms - pathology | Fatty Liver, Alcoholic - pathology | Liver Neoplasms - enzymology | Fatty Liver, Alcoholic - enzymology | Hepatitis B, Chronic - pathology | Liver Cirrhosis - genetics | Hemochromatosis - genetics | Fatty Liver - genetics | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Liver Cirrhosis, Alcoholic - pathology | Membrane Proteins - genetics | Risk Factors | Hemochromatosis - enzymology | Disease Progression | Polymorphism, Genetic | Cholangitis, Sclerosing - pathology | Fatty Liver, Alcoholic - complications | Liver Cirrhosis, Alcoholic - genetics | Phenotype | Liver Cirrhosis - pathology | Carcinoma, Hepatocellular | Hepatitis C, Chronic - genetics | Lipase - genetics | Review | Gastroenterologi | Hepatocellular | Gastroenterology and Hepatology
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 501 - 520
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e45285
A role for the NADPH oxidases NOX1 and NOX2 in liver fibrosis has been proposed, but the implication of NOX4 is poorly understood yet. The aim of this work was... 
GROWTH-FACTOR-BETA | OXIDATIVE STRESS | TGF-BETA | INDUCED APOPTOSIS | ADENINE-DINUCLEOTIDE PHOSPHATE | MULTIDISCIPLINARY SCIENCES | FIBROGENESIS | DIFFERENTIATION | MESENCHYMAL TRANSITION | UP-REGULATION | Liver - virology | Hepatitis C, Chronic - pathology | Liver - enzymology | Gene Expression - drug effects | Apoptosis - drug effects | ATP Binding Cassette Transporter, Sub-Family B - deficiency | Carbon Tetrachloride | Humans | NADPH Oxidases - metabolism | Hepatitis C, Chronic - virology | Myofibroblasts - enzymology | Liver Cirrhosis - enzymology | Liver Cirrhosis - chemically induced | Liver - drug effects | Cell Transdifferentiation - drug effects | Hepatitis C, Chronic - enzymology | STAT3 Transcription Factor - deficiency | NADPH Oxidases - genetics | Hepacivirus - physiology | Hepatic Stellate Cells - virology | Myofibroblasts - virology | Hepatocytes - drug effects | STAT3 Transcription Factor - genetics | Hepatic Stellate Cells - drug effects | Cyclin-Dependent Kinase Inhibitor p16 - deficiency | Hepatic Stellate Cells - enzymology | Cyclin-Dependent Kinase Inhibitor p16 - genetics | NADPH Oxidase 4 | Myofibroblasts - drug effects | Mice, Knockout | Transforming Growth Factor beta - pharmacology | Animals | Liver Cirrhosis - virology | Signal Transduction - drug effects | Biopsy | Hepatocytes - virology | Liver Cirrhosis - pathology | Mice | ATP Binding Cassette Transporter, Sub-Family B - genetics | Hepatocytes - enzymology | Oxidases | Care and treatment | Liver diseases | Research | Gene expression | Liver cells | Animal models | Biomedical research | Mesenchyme | Liver | Carbon tetrachloride | Viruses | Activation | Metastasis | Experiments | NAD(P)H oxidase | Hepatitis | Genotype & phenotype | Cell activation | NOX4 protein | Rodents | Hepatology | Gastroenterology | CYBB protein | Fibroblasts | Growth factors | Medical research | Stellate cells | Patients | Pulmonary fibrosis | Hepatocytes | Cell death | Fibrosis | Hepatitis C virus | Hepatitis C | Cancer | Apoptosis | Bile | Malalties del fetge | Cèl·lules hepàtiques
Journal Article
Liver International, ISSN 1478-3223, 09/2011, Volume 31, Issue 8, pp. 1137 - 1143
Journal Article
Journal Article
世界胃肠病学杂志:英文版(电子版), ISSN 1007-9327, 2014, Volume 20, Issue 26, pp. 8681 - 8690
AIM:To investigate the expression of P450 enzyme genes by using end-stage liver disease samples and trimmed normal Chinese donor livers.METHODS:The end-stage... 
Cytochrome | P450 | mRNA | expression | Nuclear | receptors | Hepatocellular carcinoma | Nuclear receptors | Cytochrome P450 | End-stage livers | Chinese donor livers | mRNA expression | HEPATIC EXPRESSION | CYTOCHROME-P450 | GENETIC-POLYMORPHISM | TRANSPORTERS | PXR | DRUG-METABOLIZING-ENZYMES | VARIABILITY | CIRRHOSIS | DISEASE | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | Liver Cirrhosis - ethnology | Liver - enzymology | Humans | Asian Continental Ancestry Group - genetics | Hepatitis B - virology | RNA, Messenger - analysis | End Stage Liver Disease - genetics | Liver Cirrhosis - enzymology | Case-Control Studies | Liver Cirrhosis, Alcoholic - enzymology | End Stage Liver Disease - ethnology | Liver Neoplasms - enzymology | Liver Cirrhosis, Alcoholic - ethnology | Carcinoma, Hepatocellular - ethnology | Hepatitis B - ethnology | Liver Neoplasms - virology | Cytochrome P-450 Enzyme System - analysis | Isoenzymes | Carcinoma, Hepatocellular - virology | Receptors, Cytoplasmic and Nuclear - genetics | Carcinoma, Hepatocellular - enzymology | China - epidemiology | Hepatitis B - enzymology | End Stage Liver Disease - enzymology | Liver Neoplasms - ethnology | Liver Cirrhosis - virology | Receptors, Cytoplasmic and Nuclear - analysis | Cytochrome P-450 Enzyme System - genetics | End Stage Liver Disease - diagnosis | End Stage Liver Disease - virology | Observational Study
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 06/2008, Volume 99, Issue 6, pp. 1019 - 1029
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2012, Volume 53, Issue 2, pp. 289 - 296
Reactive oxygen species (ROS) play a key role in chronic liver injury and fibrosis. Homologs of NADPH oxidases (NOXs) are major sources of ROS, but the exact... 
NADPH oxidase 4 | Liver fibrosis | Stellate cell activation | Hepatocyte apoptosis | NADPH OXIDASE | ACTIVATION | TGF-BETA | ISOFORMS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | FIBROGENESIS | MECHANISMS | HEPATIC STELLATE CELLS | ENDOCRINOLOGY & METABOLISM | NAD(P)H OXIDASES | STRESS | Liver - pathology | Pyrazoles - therapeutic use | Liver - enzymology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Bile Ducts - metabolism | Humans | NADPH Oxidases - metabolism | Hepatitis, Autoimmune - drug therapy | Hepatocytes - pathology | Smad3 Protein - metabolism | Liver Cirrhosis - enzymology | Hepatic Stellate Cells - cytology | Hepatitis, Autoimmune - pathology | Fas Ligand Protein - pharmacology | Ligation | Liver - drug effects | Gene Deletion | NADPH Oxidases - genetics | NADH, NADPH Oxidoreductases - metabolism | Hepatocytes - drug effects | Hepatic Stellate Cells - drug effects | Pyrazoles - pharmacology | Pyridines - therapeutic use | Liver Cirrhosis - drug therapy | NADH, NADPH Oxidoreductases - genetics | Bile Ducts - drug effects | NADPH Oxidases - antagonists & inhibitors | Rats | Bile Ducts - surgery | NADPH Oxidase 4 | NADPH Oxidase 1 | Reactive Oxygen Species - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Liver Cirrhosis - pathology | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Pyridines - pharmacology | Dactinomycin - pharmacology | Transforming Growth Factor beta - metabolism | Hepatitis, Autoimmune - enzymology | Hepatocytes - enzymology | Oxidases | Phosphates | Niacinamide | Purines | Liver diseases | Analysis | Liver | Fibrosis | Bone morphogenetic proteins | Transforming growth factors | Muscle proteins | Apoptosis | stellate cell activation | liver fibrosis | hepatocyte apoptosis | nicotinamide adenine dinucleotide phosphate reduced oxidase 4
Journal Article
Hepatology, ISSN 0270-9139, 12/2012, Volume 56, Issue 6, pp. 2316 - 2327
Journal Article