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Nature genetics, ISSN 1546-1718, 2011, Volume 43, Issue 4, pp. 329 - 332
Journal Article
by Nakamura, Minoru and Nishida, Nao and Kawashima, Minae and Aiba, Yoshihiro and Tanaka, Atsushi and Yasunami, Michio and Nakamura, Hitomi and Komori, Atsumasai and Nakamuta, Makoto and Zeniya, Mikio and Hashimoto, Etsuko and Ohira, Hiromasa and Yamamoto, Kazuhide and Onji, Morikazu and Kaneko, Shuichi and Honda, Masao and Yamagiwa, Satoshi and Nakao, Kazuhiko and Ichida, Takafumi and Takikawa, Hajime and Seike, Masataka and Umemura, Takeji and Ueno, Yoshiyuki and Sakisaka, Shotaro and Kikuchi, Kentaro and Ebinuma, Hirotoshi and Yamashiki, Noriyo and Tamura, Sumito and Sugawara, Yasuhiko and Mori, Akira and Yagi, Shintaro and Shirabe, Ken and Taketomi, Akinobu and Arai, Kuniaki and Monoe, Kyoko and Ichikawa, Tatsuki and Taniai, Makiko and Miyake, Yasuhiro and Kumagi, Teru and Abe, Masanori and Yoshizawa, Kaname and Joshita, Satoru and Shimoda, Shinji and Honda, Koichi and Takahashi, Hiroki and Hirano, Katsuji and Takeyama, Yasuaki and Harada, Kenichi and Migita, Kiyoshi and Ito, Masahiro and Yatsuhashi, Hiroshi and Fukushima, Nobuyoshi and Ota, Hajime and Komatsu, Tatsuji and Saoshiro, Takeo and Ishida, Jinya and Kouno, Hirotsugu and Kouno, Hirotaka and Yagura, Michiyasu and Kobayashi, Masakazu and Muro, Toyokichi and Masaki, Naohiko and Hirata, Keiichi and Watanabe, Yukio and Nakamura, Yoko and Shimada, Masaaki and Hirashima, Noboru and Komeda, Toshiki and Sugi, Kazuhiro and Koga, Michiaki and Ario, Keisuke and Takesaki, Eiichi and Maehara, Yoshihiko and Uemoto, Shinji and Kokudo, Norihiro and Tsubouchi, Hirohito and Mizokami, Masashi and Nakanuma, Yasuni and Tokunaga, Katsushi and Ishibashi, Hiromi
American journal of human genetics, ISSN 0002-9297, 2012, Volume 91, Issue 4, pp. 721 - 728
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2008, Volume 371, Issue 9615, pp. 838 - 851
Summary Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury, which leads to portal hypertension and end-stage liver disease... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | HEPATOCELLULAR-CARCINOMA | DECOMPENSATED CIRRHOSIS | ADEFOVIR DIPIVOXIL | CHRONIC HEPATITIS-C | HEPATOCYTE TRANSPLANTATION | SAMPLING VARIABILITY | STELLATE CELLS | FIBROSIS PROGRESSION | NONINVASIVE DIAGNOSIS | PORTAL-HYPERTENSION | Hepatitis | Liver diseases | Genetic disorders | Disease | Parasitic diseases | Mortality | Histology | Diabetes | Metabolic syndrome | Liver cirrhosis | Patients | Veins & arteries
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27087
...)-associated HCC to 80 and 81 age- and sex-matched patients with alcohol-related and HCV-related cirrhosis without HCC, respectively... 
FIBROSIS | HEPATOCELLULAR-CARCINOMA | GENE VARIANT | MULTIDISCIPLINARY SCIENCES | DISEASE | I148M | DOMAIN-CONTAINING 3 | TRENDS | SEVERITY | ADIPONUTRIN | CHILDREN | Humans | Middle Aged | Male | Case-Control Studies | Liver Neoplasms - etiology | Young Adult | Carcinoma, Hepatocellular - genetics | Aged, 80 and over | Adult | Female | Hepatitis C - complications | Carcinoma, Hepatocellular - etiology | Liver Cirrhosis - genetics | Liver Cirrhosis, Alcoholic - complications | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Liver Cirrhosis - complications | Membrane Proteins - genetics | Risk Factors | European Continental Ancestry Group | Genotype | Hepatitis C - genetics | Liver Cirrhosis, Alcoholic - genetics | Aged | Lipase - genetics | Type 2 diabetes | Obesity | Genes | Development and progression | Amino acids | Risk factors | Infection | Genetic aspects | Hepatitis C virus | Health aspects | Liver cirrhosis | Cancer | Diabetes therapy | Hepatitis B | Pediatrics | Pathogenesis | Liver | Viruses | Lipids | Hepatocellular carcinoma | Homozygosity | Gene polymorphism | Alcohol use | Proteins | Confidence intervals | Hepatitis | Liver cancer | Genotype & phenotype | Rodents | Hepatology | Gastroenterology | Genotypes | Isoleucine | Liver diseases | Statistical analysis | Hematology | Internal medicine | Diabetes mellitus | Cloning | Health risks | Methionine | Patients | Disease control | Medicine | Cirrhosis | Hospitals | Damage detection | Alcoholic beverages | Mutation | Hepatitis C | Polymorphism
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2012, Volume 143, Issue 3, pp. 765 - 776.e3
Background & Aims Interleukin (IL)-17 signaling has been implicated in lung and skin fibrosis. We examined the role of IL-17 signaling in the pathogenesis of... 
Gastroenterology and Hepatology | Immune Response | Myofibroblast | Bone Marrow-Derived Macrophages | Mouse Model | RAT-LIVER | TARGET | IL-17 RECEPTOR | HEPATOCYTES | FAMILY-MEMBERS | STAT3 | TRANSDUCTION | PATHWAY | DISEASE | GENE-EXPRESSION | GASTROENTEROLOGY & HEPATOLOGY | Kupffer Cells - pathology | Liver - pathology | Carbon Tetrachloride | Humans | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Receptors, Interleukin-17 - genetics | Interleukin-23 - genetics | Receptors, Interleukin-17 - deficiency | Interleukins - genetics | Liver Cirrhosis, Experimental - prevention & control | Liver - immunology | Time Factors | Bone Marrow Transplantation | Liver Cirrhosis, Alcoholic - immunology | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-17 - administration & dosage | Liver Cirrhosis, Experimental - immunology | Signal Transduction | Liver Cirrhosis, Alcoholic - pathology | Liver - metabolism | Interleukin-17 - genetics | Genotype | Bile Ducts - surgery | Disease Progression | Mice, Knockout | Interleukin-17 - metabolism | Phenotype | Interleukins - deficiency | Mice | Liver Cirrhosis, Experimental - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation Mediators - administration & dosage | Liver Cirrhosis, Experimental - etiology | Interleukin-23 - deficiency | Ligation | Hepatic Stellate Cells - immunology | Inflammation Mediators - metabolism | STAT3 Transcription Factor - deficiency | Liver Cirrhosis, Experimental - pathology | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Cell Line | Interleukin-1 - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-17 - deficiency | Liver Cirrhosis, Experimental - genetics | Animals | Interleukins - administration & dosage | Kupffer Cells - immunology | Medical colleges | Liver diseases | Liver | Carbon tetrachloride | Transforming growth factors | Muscle proteins | Macrophages | Endothelium | Messenger RNA | Interleukins | Actin | Analysis | Collagen | Fibrosis | Liver cirrhosis | Index Medicus | Abridged Index Medicus
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2013, Volume 144, Issue 5, pp. 1024 - 1030
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 54, Issue 4, pp. 716 - 722
.... Methods A RFLP-PCR technique was used to genotype 412 patients with cirrhosis due to hepatitis C ( n = 199), hepatitis B ( n = 75), alcohol ( n = 110), and other causes ( n = 28... 
Gastroenterology and Hepatology | Interleukin 28B | Hepatocellular carcinoma | Hepatitis C | Liver cirrhosis | Genetic polymorphisms | IFN-LAMBDA | III INTERFERONS | ANTITUMOR-ACTIVITY | GENETIC-VARIATION | IL28B | HEPATOCELLULAR-CARCINOMA | POTENT ANTIVIRAL ACTIVITY | IN-VIVO | C VIRUS | INFECTION | GASTROENTEROLOGY & HEPATOLOGY | Liver Cirrhosis - immunology | Liver Transplantation | Hepatitis B, Chronic - immunology | Humans | Middle Aged | Male | DNA Primers - genetics | Hepatitis C, Chronic - complications | Liver Neoplasms - etiology | Young Adult | Interleukins - genetics | Hepatitis B, Chronic - genetics | Base Sequence | Carcinoma, Hepatocellular - genetics | Aged, 80 and over | Adult | Female | Liver Cirrhosis, Alcoholic - immunology | Carcinoma, Hepatocellular - etiology | Carcinoma, Hepatocellular - immunology | Liver Cirrhosis - genetics | Liver Cirrhosis, Alcoholic - complications | Liver Neoplasms - genetics | Liver Cirrhosis - complications | Gene Frequency | Risk Factors | Liver Neoplasms - immunology | Liver Cirrhosis, Alcoholic - genetics | Hepatitis B, Chronic - complications | Alleles | Hepatitis C, Chronic - immunology | Liver Cirrhosis - surgery | Aged | Polymorphism, Single Nucleotide | Hepatitis C, Chronic - genetics | Cohort Studies | Care and treatment | Interleukins | Genes | Transplantation of organs, tissues, etc | Biological response modifiers | Hepatitis C virus
Journal Article
Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, 05/2015, Volume 39, Issue 5, pp. 836 - 842
Journal Article