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Drugs, ISSN 0012-6667, 2/2019, Volume 79, Issue S1, pp. 17 - 21
Neuropathology of hepatic encephalopathy (HE) in cirrhosis is primarily astroglial in nature characterized by Alzheimer type 2 astrocytosis together with activation of microglia indicative of neuroinflammation... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | PATHOGENESIS | AMMONIA | HYPERAMMONEMIA | LIVER | GABA | RATS | PHARMACOLOGY & PHARMACY | NECROSIS-FACTOR-ALPHA | TOXICOLOGY | BINDING-SITES | BRAIN | Liver Cirrhosis - drug therapy | Hepatic Encephalopathy - metabolism | Neurotransmitter Agents - antagonists & inhibitors | Ammonia - metabolism | Basal Ganglia - physiopathology | gamma-Aminobutyric Acid - metabolism | Humans | Hepatic Encephalopathy - physiopathology | Cerebellum - physiopathology | Hepatic Encephalopathy - drug therapy | Manganese - metabolism | Thalamus - physiopathology | Liver Cirrhosis - metabolism | Liver Cirrhosis - physiopathology | Inflammation - physiopathology | Cerebellum | Neuroimaging | Metabolic rate | Coma | Brain | Neurosciences | Basal ganglia | Dehydrogenases | Neuropathology | Pathogenesis | Liver | Systematic review | Activation | Reduction | γ-Aminobutyric acid | Encephalopathy | Hepatology | Thalamus | Movement disorders | Enzymes | Cortex (cingulate) | Medical imaging | Deactivation | Central nervous system diseases | Inflammation | Metabolism | Ganglia | Microglia | Neurology | Ammonia | Cirrhosis | Neurotransmitters | Gliosis | Medical prognosis | TNF inhibitors | Binding sites | Hepatic encephalopathy | Manganese
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2012, Volume 143, Issue 3, pp. 765 - 776.e3
Background & Aims Interleukin (IL)-17 signaling has been implicated in lung and skin fibrosis. We examined the role of IL-17 signaling in the pathogenesis of... 
Gastroenterology and Hepatology | Immune Response | Myofibroblast | Bone Marrow-Derived Macrophages | Mouse Model | RAT-LIVER | TARGET | IL-17 RECEPTOR | HEPATOCYTES | FAMILY-MEMBERS | STAT3 | TRANSDUCTION | PATHWAY | DISEASE | GENE-EXPRESSION | GASTROENTEROLOGY & HEPATOLOGY | Kupffer Cells - pathology | Liver - pathology | Carbon Tetrachloride | Humans | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Receptors, Interleukin-17 - genetics | Interleukin-23 - genetics | Receptors, Interleukin-17 - deficiency | Interleukins - genetics | Liver Cirrhosis, Experimental - prevention & control | Liver - immunology | Time Factors | Bone Marrow Transplantation | Liver Cirrhosis, Alcoholic - immunology | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-17 - administration & dosage | Liver Cirrhosis, Experimental - immunology | Signal Transduction | Liver Cirrhosis, Alcoholic - pathology | Liver - metabolism | Interleukin-17 - genetics | Genotype | Bile Ducts - surgery | Disease Progression | Mice, Knockout | Interleukin-17 - metabolism | Phenotype | Interleukins - deficiency | Mice | Liver Cirrhosis, Experimental - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation Mediators - administration & dosage | Liver Cirrhosis, Experimental - etiology | Interleukin-23 - deficiency | Ligation | Hepatic Stellate Cells - immunology | Inflammation Mediators - metabolism | STAT3 Transcription Factor - deficiency | Liver Cirrhosis, Experimental - pathology | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Cell Line | Interleukin-1 - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-17 - deficiency | Liver Cirrhosis, Experimental - genetics | Animals | Interleukins - administration & dosage | Kupffer Cells - immunology | Medical colleges | Liver diseases | Liver | Carbon tetrachloride | Transforming growth factors | Muscle proteins | Macrophages | Endothelium | Messenger RNA | Interleukins | Actin | Analysis | Collagen | Fibrosis | Liver cirrhosis | Index Medicus | Abridged Index Medicus
Journal Article
Gut, ISSN 0017-5749, 08/2016, Volume 65, Issue 8, pp. 1369 - 1376
... (Metavir fibrosis stage ≥F2) and 15% had cirrhosis (F4). In multivariable analysis, gamma-glutamyl transpeptidase (GGT... 
TRANSIENT ELASTOGRAPHY | BIOMARKERS | SIMPLE NONINVASIVE INDEX | MARKER | CHRONIC HEPATITIS-B | AMINOTRANSFERASE | STIFFNESS MEASUREMENT | FIBROTEST | GASTROENTEROLOGY & HEPATOLOGY | VIRAL-HEPATITIS | DIAGNOSTIC-ACCURACY | Severity of Illness Index | Liver Cirrhosis - etiology | Predictive Value of Tests | Liver - pathology | Liver Cirrhosis - diagnosis | Area Under Curve | gamma-Glutamyltransferase - blood | Humans | Middle Aged | Biomarkers - analysis | Male | Dimensional Measurement Accuracy | Biomarkers - blood | Hepatitis B, Chronic - diagnosis | Africa, Western - epidemiology | Patient Acuity | Hepatitis B, Chronic - complications | Platelet Count - methods | gamma-Glutamyltransferase - analysis | Biopsy | Liver Cirrhosis - pathology | Adult | Female | Hepatitis B, Chronic - pathology | Complications and side effects | Analysis | Patients | Health aspects | Liver cirrhosis | Risk factors | Hepatitis B | Peptidyl transferases | Hepatitis B, Chronic / complications | Liver Cirrhosis / pathology | Liver / pathology | Biomarkers / analysis | Life Sciences | Africa, Western / epidemiology | gamma-Glutamyltransferase / blood | Biomarkers / blood | Hepatitis B, Chronic / pathology | Liver Cirrhosis / diagnosis | Hepatitis B, Chronic / diagnosis | gamma-Glutamyltransferase / analysis | Santé publique et épidémiologie | Liver Cirrhosis / etiology | Platelet Count / methods | FIBROSIS | HEPATITIS B | 1506 | Hepatology
Journal Article
Liver international, ISSN 1478-3223, 2012, Volume 32, Issue 2, pp. 199 - 213
Journal Article
Hepatology, ISSN 0270-9139, 09/2010, Volume 52, Issue 3, pp. 987 - 998
Journal Article