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Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 11/2013, Volume 19, Issue 41, pp. 6969 - 6978
The 148 Isoleucine to Methionine protein variant (I148M) of patatin-like phospholipase domain-containing 3 (PNPLA3), a protein is expressed in the liver and is... 
Liver disease | Patatin-like phospholipase domain-containing 3 | Chronic hepatitis C virus hepatitis | Genetics | Hepatocellular carcinoma | Nonalcoholic fatty liver disease | Single nucleotide polymorphism | Fibrogenesis | Alcoholic liver disease | Steatosis | CHRONIC HEPATITIS-C | NONALCOHOLIC STEATOHEPATITIS | GREATER-THAN-G | B-VIRUS INFECTION | HEPATOCELLULAR-CARCINOMA | INSULIN-RESISTANCE | FATTY LIVER | DOMAIN-CONTAINING 3 | GENETIC VARIANT | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Cholangitis, Sclerosing - enzymology | Hepatitis C, Chronic - pathology | Fatty Liver - pathology | Humans | Cholangitis, Sclerosing - genetics | Fatty Liver - complications | Hepatitis B, Chronic - enzymology | Hepatitis C, Chronic - complications | Liver Cirrhosis - enzymology | Hemochromatosis - pathology | Fatty Liver, Alcoholic - genetics | Hepatitis B, Chronic - genetics | Liver Cirrhosis, Alcoholic - enzymology | Hepatitis C, Chronic - enzymology | Fatty Liver - enzymology | Non-alcoholic Fatty Liver Disease | Liver Neoplasms - pathology | Fatty Liver, Alcoholic - pathology | Liver Neoplasms - enzymology | Fatty Liver, Alcoholic - enzymology | Hepatitis B, Chronic - pathology | Liver Cirrhosis - genetics | Hemochromatosis - genetics | Fatty Liver - genetics | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Liver Cirrhosis, Alcoholic - pathology | Membrane Proteins - genetics | Risk Factors | Hemochromatosis - enzymology | Disease Progression | Polymorphism, Genetic | Cholangitis, Sclerosing - pathology | Fatty Liver, Alcoholic - complications | Liver Cirrhosis, Alcoholic - genetics | Phenotype | Liver Cirrhosis - pathology | Carcinoma, Hepatocellular | Hepatitis C, Chronic - genetics | Lipase - genetics | Review | Gastroenterologi | Hepatocellular | Gastroenterology and Hepatology
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2011, Volume 55, Issue 4, pp. 906 - 912
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27087
Background: An isoleucine. methionine mutation at position 148 in the PNPLA3 gene (p. I148M, rs738409) has recently been identified as a susceptibility factor... 
FIBROSIS | HEPATOCELLULAR-CARCINOMA | GENE VARIANT | MULTIDISCIPLINARY SCIENCES | DISEASE | I148M | DOMAIN-CONTAINING 3 | TRENDS | SEVERITY | ADIPONUTRIN | CHILDREN | Humans | Middle Aged | Male | Case-Control Studies | Liver Neoplasms - etiology | Young Adult | Carcinoma, Hepatocellular - genetics | Aged, 80 and over | Adult | Female | Hepatitis C - complications | Carcinoma, Hepatocellular - etiology | Liver Cirrhosis - genetics | Liver Cirrhosis, Alcoholic - complications | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Liver Cirrhosis - complications | Membrane Proteins - genetics | Risk Factors | European Continental Ancestry Group | Genotype | Hepatitis C - genetics | Liver Cirrhosis, Alcoholic - genetics | Aged | Lipase - genetics | Type 2 diabetes | Obesity | Genes | Development and progression | Amino acids | Risk factors | Infection | Genetic aspects | Hepatitis C virus | Health aspects | Liver cirrhosis | Cancer | Diabetes therapy | Hepatitis B | Pediatrics | Pathogenesis | Liver | Viruses | Lipids | Hepatocellular carcinoma | Alcohol | Homozygosity | Gene polymorphism | Alcohol use | Proteins | Confidence intervals | Hepatitis | Liver cancer | Genotype & phenotype | Rodents | Hepatology | Gastroenterology | Genotypes | Isoleucine | Liver diseases | Statistical analysis | Hematology | Internal medicine | Diabetes mellitus | Cloning | Health risks | Methionine | Patients | Disease control | Medicine | Cirrhosis | Hospitals | Damage detection | Hepatitis C | Polymorphism
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 54, Issue 4, pp. 716 - 722
Background & Aims A single nucleotide polymorphism (rs12979860 C/T) 3 kb upstream of the interleukin 28B ( IL-28B ) gene was shown to be associated with... 
Gastroenterology and Hepatology | Interleukin 28B | Hepatocellular carcinoma | Hepatitis C | Liver cirrhosis | Genetic polymorphisms | IFN-LAMBDA | III INTERFERONS | ANTITUMOR-ACTIVITY | GENETIC-VARIATION | IL28B | HEPATOCELLULAR-CARCINOMA | POTENT ANTIVIRAL ACTIVITY | IN-VIVO | C VIRUS | INFECTION | GASTROENTEROLOGY & HEPATOLOGY | Liver Cirrhosis - immunology | Liver Transplantation | Hepatitis B, Chronic - immunology | Humans | Middle Aged | Male | DNA Primers - genetics | Hepatitis C, Chronic - complications | Liver Neoplasms - etiology | Young Adult | Interleukins - genetics | Hepatitis B, Chronic - genetics | Base Sequence | Carcinoma, Hepatocellular - genetics | Aged, 80 and over | Adult | Female | Liver Cirrhosis, Alcoholic - immunology | Carcinoma, Hepatocellular - etiology | Carcinoma, Hepatocellular - immunology | Liver Cirrhosis - genetics | Liver Cirrhosis, Alcoholic - complications | Liver Neoplasms - genetics | Liver Cirrhosis - complications | Gene Frequency | Risk Factors | Liver Neoplasms - immunology | Liver Cirrhosis, Alcoholic - genetics | Hepatitis B, Chronic - complications | Alleles | Hepatitis C, Chronic - immunology | Liver Cirrhosis - surgery | Aged | Polymorphism, Single Nucleotide | Hepatitis C, Chronic - genetics | Cohort Studies | Care and treatment | Interleukins | Genes | Transplantation of organs, tissues, etc | Biological response modifiers | Hepatitis C virus
Journal Article
Liver International, ISSN 1478-3223, 04/2014, Volume 34, Issue 4, pp. 514 - 520
Background & Aims Environmental and genetic factors contribute to alcoholic cirrhosis onset. In particular, age at exposure to liver stressors has been shown... 
Age at onset | alcoholic liver disease | genetics | patatin‐like phospholipase domain‐containing protein 3 | alcohol intake | polymorphism | incidence | Alcohol intake | Patatin-like phospholipase domain-containing protein 3 | Genetics | Alcoholic liver disease | Incidence | Polymorphism | patatin-like phospholipase domain-containing protein 3 | HISTOLOGICAL SEVERITY | FATTY LIVER-DISEASE | CHRONIC HEPATITIS-C | SUSCEPTIBILITY | FIBROSIS PROGRESSION | DAMAGE | TRANSPLANTATION | HEPATOCELLULAR-CARCINOMA | GASTROENTEROLOGY & HEPATOLOGY | INDEXES | Membrane Proteins - genetics | Humans | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Genotype | Linear Models | Mutation, Missense - genetics | Liver Cirrhosis, Alcoholic - genetics | Liver Cirrhosis, Alcoholic - epidemiology | Alcohol Drinking - epidemiology | Age of Onset | Adult | Italy | Models, Genetic | Retrospective Studies | Lipase - genetics | Genetic research | Development and progression | Phospholipases | Drinking of alcoholic beverages | Hepatitis C | Liver cirrhosis | Risk factors | Cirrhosis and Liver Failure | damage | hepatocellular-carcinoma | susceptibility | Gastroenterologi | fatty liver-disease | chronic hepatitis-c | indexes | patatin-like phospholipase domain-containing protein | transplantation | fibrosis progression | histological severity | Gastroenterology and Hepatology
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 06/2015, Volume 110, Issue 6, pp. 846 - 856
Journal Article
Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, 08/2013, Volume 37, Issue 8, pp. 1391 - 1401
Journal Article