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Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 09/2012, Volume 143, Issue 3, pp. 765 - 776.e3
Background & Aims Interleukin (IL)-17 signaling has been implicated in lung and skin fibrosis. We examined the role of IL-17 signaling in the pathogenesis of... 
Gastroenterology and Hepatology | Immune Response | Myofibroblast | Bone Marrow-Derived Macrophages | Mouse Model | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Kupffer Cells - pathology | Liver - pathology | Carbon Tetrachloride | Humans | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Receptors, Interleukin-17 - genetics | Interleukin-23 - genetics | Receptors, Interleukin-17 - deficiency | Interleukins - genetics | Liver Cirrhosis, Experimental - prevention & control | Liver - immunology | Time Factors | Bone Marrow Transplantation | Liver Cirrhosis, Alcoholic - immunology | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-17 - administration & dosage | Liver Cirrhosis, Experimental - immunology | Signal Transduction | Liver Cirrhosis, Alcoholic - pathology | Liver - metabolism | Interleukin-17 - genetics | Genotype | Bile Ducts - surgery | Disease Progression | Mice, Knockout | Interleukin-17 - metabolism | Phenotype | Interleukins - deficiency | Mice | Liver Cirrhosis, Experimental - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation Mediators - administration & dosage | Liver Cirrhosis, Experimental - etiology | Interleukin-23 - deficiency | Ligation | Hepatic Stellate Cells - immunology | Inflammation Mediators - metabolism | STAT3 Transcription Factor - deficiency | Liver Cirrhosis, Experimental - pathology | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Cell Line | Interleukin-1 - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-17 - deficiency | Liver Cirrhosis, Experimental - genetics | Animals | Interleukins - administration & dosage | Kupffer Cells - immunology | Medical colleges | Liver diseases | Liver | Carbon tetrachloride | Transforming growth factors | Muscle proteins | Macrophages | Endothelium | Messenger RNA | Interleukins | Actin | Analysis | Collagen | Fibrosis | Liver cirrhosis | Index Medicus | Abridged Index Medicus
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2014, Volume 146, Issue 5, pp. 1339 - 1350.e1
Background & Aims Vascular endothelial growth factor (VEGF)−induced angiogenesis is implicated in fibrogenesis and portal hypertension. However, the function... 
Gastroenterology and Hepatology | Extracellular Matrix | Sinusoidal Endothelial Cell | Liver Damage | Hepatic Sinusoid | Keywords | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Antibodies, Neutralizing - administration & dosage | Liver - pathology | Capillary Permeability | Human Umbilical Vein Endothelial Cells - metabolism | Carbon Tetrachloride | Coculture Techniques | Humans | Monocytes - metabolism | Monocytes - immunology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | fas Receptor - metabolism | Liver Cirrhosis, Experimental - prevention & control | Liver - immunology | Ligation | Cholecystostomy | Adenoviridae - genetics | Liver Cirrhosis, Experimental - pathology | Macrophages - immunology | Tacrolimus Binding Protein 1A - genetics | Gene Transfer Techniques | Promoter Regions, Genetic | Liver Regeneration | Liver Cirrhosis, Experimental - immunology | Jejunostomy | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Receptor, Macrophage Colony-Stimulating Factor - genetics | Mice, Transgenic | Vascular Endothelial Growth Factor A - immunology | Bile Ducts - surgery | Liver Cirrhosis, Experimental - genetics | Remission Induction | Matrix Metalloproteinase 13 - metabolism | Injections | Macrophages - metabolism | Animals | Chemokine CXCL9 - metabolism | Liver Cirrhosis, Experimental - chemically induced | Tacrolimus Binding Protein 1A - metabolism | Mice | Genetic Vectors | Liver Cirrhosis, Experimental - metabolism | Apoptosis | Hypertension | Medical colleges | Vascular endothelial growth factor | Health aspects | Fibrosis
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 10/2017, Volume 153, Issue 4, pp. 996 - 1005.e1
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 12/2015, Volume 289, Issue 2, pp. 163 - 176
SIRT1 (silent information regulator 1), a conserved NAD+-dependent histone deacetylase, is closely related with various biological processes. Moreover, the... 
Reversion | MALAT1 | Liver fibrosis | SIRT1 | Apoptosis | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Sirtuin 1 - metabolism | Liver - pathology | Liver - enzymology | Apoptosis - drug effects | Carbon Tetrachloride | Humans | Actins - metabolism | Myofibroblasts - enzymology | Male | RNA, Messenger - metabolism | Xanthines - pharmacology | Sirtuin 1 - genetics | Actins - genetics | Dose-Response Relationship, Drug | Liver Cirrhosis, Experimental - prevention & control | Liver Cirrhosis, Experimental - enzymology | Collagen Type I - genetics | Dexamethasone - pharmacology | Transfection | Liver - drug effects | RNA Interference | Time Factors | Liver Cirrhosis, Experimental - pathology | Female | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - enzymology | Chemical and Drug Induced Liver Injury - etiology | Hepatic Stellate Cells - pathology | Transforming Growth Factor beta1 - pharmacology | Hepatic Stellate Cells - drug effects | Cell Line | Chemical and Drug Induced Liver Injury - prevention & control | Insulin - pharmacology | Myofibroblasts - pathology | Collagen Type I - metabolism | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Hepatic Stellate Cells - enzymology | Chemical and Drug Induced Liver Injury - genetics | Liver Cirrhosis, Experimental - genetics | Phenotype | Animals | Liver Cirrhosis, Experimental - chemically induced | RNA, Long Noncoding - metabolism | Corticosteroids | Liver | Analysis | Fibrosis | Bone morphogenetic proteins | Transforming growth factors | Liver cirrhosis | Index Medicus | APOPTOSIS | DEXAMETHASONE | COLLAGEN | RNA | LUNGS | METASTASES | 60 APPLIED LIFE SCIENCES | HISTONES | MICE | VIRUSES | FIBROSIS | ONCOGENES | TRANSCRIPTION FACTORS | ACTIN | MATERIALS RECOVERY | STEROLS | TRANSCRIPTION | PHENOTYPE | INSULIN | NAD | GROWTH FACTORS | CARBON TETRACHLORIDE | LIVER | CARCINOMAS | RECEPTORS | MUSCLES
Journal Article
Journal of hepatology, ISSN 0168-8278, 05/2013, Volume 58, Issue 5, pp. 904 - 910
Journal Article
BMC complementary and alternative medicine, ISSN 1472-6882, 03/2013, Volume 13, Issue 1, pp. 56 - 56
Background: Hepatology research has focused on developing traditional therapies as pharmacological medicines to treat liver cirrhosis... 
Immunohistochemistry | Cytochrome P450 2E1 (CYP2E1) | Oxidative stress | Histology | Curcuma longa | Antioxidant enzymes | Life Sciences & Biomedicine | Integrative & Complementary Medicine | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Liver - pathology | Apoptosis - drug effects | Plant Extracts - pharmacology | Transforming Growth Factor beta1 - metabolism | Cytochrome P-450 CYP2E1 - metabolism | Liver Cirrhosis, Experimental - prevention & control | Proto-Oncogene Proteins c-bcl-2 - metabolism | Liver - drug effects | Rhizome | Anti-Inflammatory Agents - therapeutic use | Liver Cirrhosis, Experimental - pathology | Phytotherapy | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Disease Models, Animal | Malondialdehyde - metabolism | Chemical and Drug Induced Liver Injury - prevention & control | Anti-Inflammatory Agents - pharmacology | Liver - metabolism | Rats | Antioxidants - pharmacology | Rats, Sprague-Dawley | Thioacetamide | Antioxidants - therapeutic use | Animals | Chemical and Drug Induced Liver Injury - metabolism | Cell Proliferation - drug effects | Curcuma | Oxidative Stress - drug effects | Plant Extracts - therapeutic use | Liver Cirrhosis, Experimental - metabolism | Medicinal plants | Antigens | Biological products | Cytochrome P-450 | Alcohol | Research | Transforming growth factors | Antioxidants | Turmeric | Alcohol, Denatured | Tumor necrosis factor | Bone morphogenetic proteins | Liver cirrhosis | Apoptosis | Medicine | Studies | Medical research | Wound healing | Acids | Ethanol | Rodents | Laboratory animals | Drug dosages
Journal Article
Journal Article
European journal of pharmacology, ISSN 0014-2999, 2008, Volume 595, Issue 1, pp. 69 - 77
Three important features must be considered when proposing therapeutic strategies in liver cirrhosis... 
Gastrointestinal and urogenital pharmacology | Pirfenidone | Experimental liver | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Proto-Oncogene Proteins c-met - metabolism | Liver - pathology | Superoxide Dismutase - genetics | Liver - enzymology | Rats, Wistar | Carbon Tetrachloride | Liver Cirrhosis, Experimental - etiology | Nitrites - metabolism | NF-kappa B - metabolism | Alanine Transaminase - blood | Liver Cirrhosis, Experimental - prevention & control | Liver Cirrhosis, Experimental - enzymology | Collagen Type I - genetics | Ligation | Liver - drug effects | Hepatocyte Growth Factor - genetics | Liver Cirrhosis, Experimental - pathology | Common Bile Duct - surgery | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Collagen Type I - metabolism | Catalase - genetics | Rats | Antioxidants - pharmacology | Onium Compounds - pharmacology | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins c-met - genetics | Catalase - metabolism | Bilirubin - blood | Animals | Transforming Growth Factor beta - genetics | Aspartate Aminotransferases - blood | Nitric Oxide Synthase Type II - genetics | Oxidative Stress - drug effects | Transforming Growth Factor beta - metabolism | Pyridones - pharmacology | Nitric Oxide Synthase Type II - metabolism | Antioxidants | Analysis | Carbon tetrachloride | Superoxide dismutase | Transforming growth factors | Gene expression | Liver cirrhosis
Journal Article
Journal Article