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1. Liver failure
: etiologies, neurological complications and emerging therapies
by Peralta, Carmen, editor of compilation and Fontana, Luis, editor of compilation
2013, Hepatology research and clinical developments, ISBN 9781628085242
Biliary tract | Treatment | Liver | Failure | Diseases
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2. Full Text Fulminant hepatic failure: Etiology and indications for liver transplantation
by Gotthardt, Daniel and Riediger, Carina and Weiss, Karl Heinz and Encke, Jens and Schemmer, Peter and Schmidt, Jan and Sauer, Peter
Nephrology Dialysis Transplantation, ISSN 0931-0509, 09/2007, Volume 22, Issue 8, pp. viii5 - viiii8
Fulminant hepatic failure is characterized by the development of severe liver injury with impaired synthetic capacity and encephalopathy in patients with... 
Fulminant hepatic failure | Liver transplantation | MULTICENTER | AREA | PROGNOSIS | fulminant hepatic failure | UROLOGY & NEPHROLOGY | BUDD-CHIARI-SYNDROME | HEPATOTOXICITY | E VIRUS-INFECTION | VIRAL-HEPATITIS | liver transplantation | TRANSPLANTATION | Liver - pathology | Prognosis | Humans | Middle Aged | Hepatitis - therapy | Hepatitis - pathology | Liver Failure, Acute - etiology | Treatment Outcome | Liver Failure, Acute - therapy | Fibrosis - therapy | Liver Transplantation - methods | Liver Failure - chemically induced | Tissue and Organ Procurement - methods | Adolescent | Nephrology - methods | Adult | Child
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3. Full Text Neonatal liver failure: aetiologies and management—state of the art
by Shanmugam, Naresh P and Bansal, Sanjay and Greenough, Anne and Verma, Anita and Dhawan, Anil
European Journal of Pediatrics, ISSN 0340-6199, 5/2011, Volume 170, Issue 5, pp. 573 - 581
Acute liver failure in neonates is rare, but carries a high mortality. Neonatal liver failure can be defined as “failure of the synthetic function of liver... 
Haemophagocytic lymphohistiocytosis | Pediatrics | Acute liver failure | Mitochondrial disorders | Hepatocyte transplantation | Medicine & Public Health | Neonatal liver failure | Liver transplantation | Neonatal hemochromatosis | FULMINANT-HEPATITIS | SIMPLEX-VIRUS-INFECTIONS | FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | IMMUNOGLOBULIN | BACTERIAL | TRANSPLANTATION | TYROSINEMIA TYPE-I | DISEASE | PEDIATRICS | GALACTOSEMIA | HEMOCHROMATOSIS | Liver Transplantation | Hemochromatosis - complications | Humans | Liver Failure, Acute - diagnosis | Herpes Simplex - complications | Liver Failure, Acute - etiology | Liver Failure, Acute - therapy | Infant, Newborn | Metabolism, Inborn Errors - complications | Lymphohistiocytosis, Hemophagocytic - complications | Virus diseases | Infants (Newborn) | Transplantation of organs, tissues, etc | Liver failure
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4. Full Text Pediatric acute liver failure: Etiology, outcomes, and the role of serial pediatric end‐stage liver disease scores
by Rajanayagam, Jeremy and Coman, David and Cartwright, David and Lewindon, Peter J
Pediatric Transplantation, ISSN 1397-3142, 06/2013, Volume 17, Issue 4, pp. 362 - 368
To describe etiology, short‐term outcomes and prognostic accuracy of serial PELD scores in PALF . Retrospective analysis of children aged ≤16 yr, admitted with... 
pediatric acute liver failure | pediatric end‐stage liver disease | pediatric end-stage liver disease | INDICATORS | PEDIATRICS | FULMINANT HEPATIC-FAILURE | CHILDREN | TRANSPLANTATION | End Stage Liver Disease - therapy | Severity of Illness Index | Liver Transplantation | Prognosis | Humans | Child, Preschool | Infant | Liver Failure, Acute - epidemiology | Liver Failure, Acute - etiology | Liver Failure, Acute - mortality | Male | Treatment Outcome | Liver Failure, Acute - therapy | Hepatic Encephalopathy - therapy | Time Factors | Adolescent | Female | Hepatic Encephalopathy - etiology | Registries | Referral and Consultation | Retrospective Studies | Child | Queensland | Pediatrics | Liver failure | Analysis | Development and progression | Bilirubin | Causes and theories of causation | Diseases
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5. Full Text Acute liver failure, etiology, and outcome: An experience in a referral liver transplant center
by Moini, Maryam and Pahlevan-Sabagh, Mohammad-Reza and Dehghani, Seyedmohsen
Hepatitis Monthly, ISSN 1735-143X, 06/2017, Volume 17, Issue 6
Background and Aims: Acute liver failure (ALF) caused by a sudden loss of liver function in patients without pre-existing liver disease is a rare condition and... 
UNITED-STATES | DIAGNOSIS | AUTOIMMUNE HEPATITIS | GASTROENTEROLOGY & HEPATOLOGY | Pediatrics | Liver diseases | Transplants & implants | Viruses | Alcohol | Drug overdose | Family medical history | Patients | Hepatitis | Hospitals | Analgesics | Etiology | Hepatology | Medical prognosis
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6. Full Text Fibrosis — A Common Pathway to Organ Injury and Failure
by Rockey, Don C and Bell, P. Darwin and Hill, Joseph A
The New England Journal of Medicine, ISSN 0028-4793, 03/2015, Volume 372, Issue 12, pp. 1138 - 1149
Fibrosis is a consequence of the inflammatory response. When fibrotic tissue becomes excessive, it can have diverse pathophysiological effects on a number of... 
CONTROLLED CLINICAL-TRIAL | MEDICINE, GENERAL & INTERNAL | CARDIOVASCULAR MAGNETIC-RESONANCE | CHRONIC HEPATITIS-B | LIVER FIBROSIS | SKIN FIBROSIS | OPEN-LABEL | PLACEBO-CONTROLLED TRIAL | IDIOPATHIC PULMONARY-FIBROSIS | MESENCHYMAL TRANSITION | MOLECULAR-MECHANISMS | Fibrosis - therapy | Fibrosis - physiopathology | Transforming Growth Factor beta - metabolism | Fibrosis - complications | Humans | Multiple Organ Failure - etiology | Cell proliferation | Care and treatment | Fibrosis | Fibroblasts | Inflammation | Research | Risk factors | Proteins | Tissue | Medical research | Pathogenesis | Extracellular matrix
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7. Full Text Severity and outcome of acute-on-chronic liver failure is dependent on the etiology of acute hepatic insults analysis of 368 patients
by Shalimar, Shalimar and Kedia, Saurabh and Mahapatra, Soumya J and Nayak, Baibaswata and Gunjan, Deepak and Thakur, Bhaskar and Acharya, Subrat K
Journal of Clinical Gastroenterology, ISSN 0192-0790, 2017, Volume 51, Issue 8, pp. 734 - 741
Background: Acute-on-chronic liver failure (ACLF) may be precipitated by various hepatic insults. The present study evaluated the outcomes of ACLF with... 
Alcohol | Liver failure | Encephalopathy | Outcome | alcohol | MORTALITY | SURVIVAL | FULMINANT-HEPATITIS | DECOMPENSATION | E VIRUS | DISTINCT | AUTOIMMUNE HEPATITIS | encephalopathy | liver failure | CIRRHOSIS | DISEASE | GASTROENTEROLOGY & HEPATOLOGY | outcome | Length of Stay | Predictive Value of Tests | Age Factors | Humans | India - epidemiology | Acute-On-Chronic Liver Failure - pathology | Male | Acute-On-Chronic Liver Failure - epidemiology | Sex Factors | Survival Analysis | Acute-On-Chronic Liver Failure - etiology | Adult | Female | Acute-On-Chronic Liver Failure - mortality | APACHE
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8. Full Text Letter: acute liver failure of indeterminate aetiology
by Fujiwara, Keiichi and Yasui, Shin and Yokosuka, Osamu and Kato, Naoya
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 11/2018, Volume 48, Issue 9, pp. 1024 - 1025
Linked Content This article is linked to Brennan et al papers. To view these articles visit https://doi.org/10.1111/apt.14566 and... 
PHARMACOLOGY & PHARMACY | HEPATITIS | GASTROENTEROLOGY & HEPATOLOGY | JAPANESE CENTER | Hepatitis | Humans | Liver Failure, Acute | Liver diseases | Liver
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9. Full Text Mechanisms and treatment of organ failure in sepsis
by Lelubre, Christophe and Vincent, Jean-Louis
Nature Reviews Nephrology, ISSN 1759-5061, 07/2018, Volume 14, Issue 7, pp. 417 - 427
Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction. Knowledge of the pathophysiology of organ failure in sepsis is... 
ACUTE KIDNEY INJURY | SPECIAL-ISSUE SEPSIS | INTENSIVE-CARE-UNIT | MEDIATES LUNG INJURY | LONG-TERM SURVIVAL | UROLOGY & NEPHROLOGY | CHOLINERGIC ANTIINFLAMMATORY PATHWAY | ACUTE-RENAL-FAILURE | CRITICALLY-ILL PATIENTS | RESPIRATORY-DISTRESS-SYNDROME | POSITIVE FLUID BALANCE | Humans | Respiratory Insufficiency - etiology | Liver Failure, Acute - etiology | Sepsis - complications | Multiple Organ Failure - therapy | Shock - etiology | Liver Failure, Acute - physiopathology | Nervous System Diseases - physiopathology | Acute Kidney Injury - etiology | Respiratory Insufficiency - physiopathology | Sepsis - immunology | Blood Coagulation Disorders - etiology | Hypoxia - etiology | Endothelium, Vascular - physiopathology | Shock - physiopathology | Biomarkers - blood | Acute Kidney Injury - physiopathology | Animals | Multiple Organ Failure - etiology | Sepsis - therapy | Nervous System Diseases - etiology | Hypoxia - physiopathology | Organ Dysfunction Scores | Sepsis - blood | Hemodynamics | Mitochondria - physiology | Multiple Organ Failure - physiopathology | Blood Coagulation Disorders - physiopathology | Apoptosis | Hypovolemia - etiology | Sepsis | Organs (Anatomy) | Diagnosis | Critically ill | Health aspects | Risk factors | Biopsy
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10. Full Text Severe toxic acute liver failure: Etiology and treatment
by Amathieu, R and Levesque, E and Merle, JC and Chemit, M and Costentin, C and Compagnon, P and Dhonneur, G
ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION, ISSN 0750-7658, 06/2013, Volume 32, Issue 6, pp. 416 - 421
Many substances, drugs or not, can be responsible for acute hepatitis. Nevertheless, toxic etiology, except when that is obvious like in acetaminophen... 
Acute liver failure | PREDICTOR | PROGNOSTIC-FACTORS | ANESTHESIOLOGY | Toxic hepatitis | Drug-induced liver injury | INFECTION | HEPATOTOXICITY | FULMINANT HEPATIC-FAILURE | INTRACRANIAL-PRESSURE | TRANSPLANTATION | Acetaminophen - adverse effects | Liver Transplantation | Sepsis - etiology | Humans | Respiratory Insufficiency - etiology | Liver Failure, Acute - therapy | Shock - etiology | Sepsis - drug therapy | Time Factors | Hepatic Encephalopathy - diagnosis | Hepatic Encephalopathy - etiology | Shock - therapy | Liver Failure, Acute - drug therapy | Acetylcysteine - therapeutic use | Acetylcysteine - administration & dosage | Mushroom Poisoning - diagnosis | Valproic Acid - adverse effects | Acute Kidney Injury - etiology | Chemical and Drug Induced Liver Injury - etiology | Liver Function Tests | Diagnosis, Differential | Anti-Infective Agents - adverse effects | Hepatic Encephalopathy - surgery | Blood Coagulation Disorders - etiology | Cholestasis - diagnosis | Anti-Infective Agents - therapeutic use | Liver Failure, Acute - chemically induced | Combined Modality Therapy | Respiratory Insufficiency - therapy | Street Drugs - adverse effects | Chemical and Drug Induced Liver Injury - diagnosis | Blood Coagulation Disorders - drug therapy | Occupational Diseases - chemically induced | Occupational Diseases - therapy | Neurologic Examination | Chemical and Drug Induced Liver Injury - therapy | Chemical and Drug Induced Liver Injury - drug therapy | Acute Kidney Injury - therapy | Disease Management | Chemical and Drug Induced Liver Injury - surgery | Hepatitis, Viral, Human - diagnosis
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11. Full Text Urinary N-acetyl-β-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure
by Liangos, Orfeas and Perianayagam, Mary C and Vaidya, Vishal S and Han, Won K and Wald, Ron and Tighiouart, Hocine and MacKinnon, Robert W and Li, Lijun and Balakrishnan, Vaidyanathapuram S and Pereira, Brian J. G and Bonventre, Joseph V and Jaber, Bertrand L
Journal of the American Society of Nephrology, ISSN 1046-6673, 03/2007, Volume 18, Issue 3, pp. 904 - 912
The role of urinary biomarkers of kidney injury in the prediction of adverse clinical outcomes in acute renal failure (ARF) has not been well described. The... 
MORTALITY | BIOMARKER | MODELS | INTENSIVE-CARE-UNIT | CARDIAC-SURGERY | BETA-D-GLUCOSAMINIDASE | DISEASE | ENZYMURIA | UROLOGY & NEPHROLOGY | CARDIOPULMONARY BYPASS | EPIDEMIOLOGY | Acute Kidney Injury - urine | Liver Cirrhosis - etiology | Membrane Glycoproteins - urine | Sepsis - etiology | Biomarkers - urine | Prognosis | Prospective Studies | Hospital Mortality | Area Under Curve | Humans | Middle Aged | Logistic Models | Male | Renal Dialysis - statistics & numerical data | Oliguria - etiology | Hepatitis A Virus Cellular Receptor 1 | Acute Kidney Injury - complications | Multiple Organ Failure - etiology | Respiration, Artificial - statistics & numerical data | Female | Aged | Acetylglucosaminidase - urine | APACHE | Receptors, Virus
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12. Full Text Severe toxic acute liver failure: Etiology and treatment
by Amathieu, R and Levesque, E and Merle, J.-C and Chemit, M and Costentin, C and Compagnon, P and Dhonneur, G
Annales francaises d'anesthesie et de reanimation, ISSN 0750-7658, 06/2013, Volume 32, Issue 6, p. 416
De nombreuses substances, medicamenteuses ou non, peuvent etre responsables d'hepatite aigue. Cependant, l'origine toxique, hormis lorsqu'elle est evidente,... 
Liver diseases | Antitubercular agents
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13. Full Text Acute on chronic liver failure because of acute hepatic insults: Etiologies, course, extrahepatic organ failure and predictors of mortality
by Shalimar and Kumar, Dharmendra and Vadiraja, Padmaprakash Kadavoor and Nayak, Baibaswata and Thakur, Bhaskar and Das, Prasenjit and Datta Gupta, Siddhartha and Panda, Subrat Kumar and Acharya, Subrat Kumar
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 04/2016, Volume 31, Issue 4, pp. 856 - 864
Background and Aim:Acute on chronic liver failure (ACLF) because of precipitating factors (variceal bleed/infections) identifies cirrhotics at risk for high... 
silent | hepatitis e virus | superinfection | organ failure | Organ failure | Silent | Superinfection | Hepatitis e virus | SURVIVAL | E VIRUS | DISTINCT | INFECTION | GASTROENTEROLOGY & HEPATOLOGY | Antitubercular Agents - adverse effects | Prospective Studies | Humans | Middle Aged | Male | Forecasting | Young Adult | Hepatitis, Autoimmune - complications | Multiple Organ Failure - etiology | Hepatitis, Chronic - complications | Acute-On-Chronic Liver Failure - etiology | Adult | Female | Hepatitis, Viral, Human - complications | Alcoholism - complications | Acute-On-Chronic Liver Failure - mortality | Hepatitis | Development and progression | Liver failure | Patient outcomes | Analysis | Mortality
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14. Full Text Acute‐on‐chronic liver failure precipitated by hepatic injury is distinct from that precipitated by extrahepatic insults
by Shi, Yu and Yang, Ying and Hu, Yaoren and Wu, Wei and Yang, Qiao and Zheng, Min and Zhang, Shun and Xu, Zhaojun and Wu, Yihua and Yan, Huadong and Chen, Zhi
Hepatology, ISSN 0270-9139, 07/2015, Volume 62, Issue 1, pp. 232 - 242
Patients with acute‐on‐chronic liver failure (ACLF) represent a heterogeneous population. The aim of the study is to identify distinct groups according to the... 
MORTALITY | ENCEPHALOPATHY | DEFINITION | ACUTE DECOMPENSATION | CLIF-SOFA | ASSESSMENT SCORE | DISEASE | CIRRHOTIC-PATIENTS | MODEL | GASTROENTEROLOGY & HEPATOLOGY | Prognosis | Humans | Middle Aged | Acute-On-Chronic Liver Failure - etiology | Adult | Female | Male | Aged | Retrospective Studies | China - epidemiology | Acute-On-Chronic Liver Failure - mortality | Acute-On-Chronic Liver Failure - diagnosis | Liver cirrhosis | Mortality | Failure
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15. Full Text The "50-50 criteria" on postoperative day 5: An accurate predictor of liver failure and death after hepatectomy
by Balzan, Silvio and Belghiti, Jacques and Farges, Olivier and Ogata, Satoshi and Sauvanet, Alain and Delefosse, Didier and Durand, Fraņois and Sloof, Sloof and Rikkers, Rikkers and Clavien, Clavien and Höckerstedt, Hockerstedt
Annals of Surgery, ISSN 0003-4932, 12/2005, Volume 242, Issue 6, pp. 824 - 829
Objective: To standardize the definition of postoperative liver failure (PLF) for prediction of early mortality after hepatectomy. Summary Background Data: The... 
MAJOR LIVER | SURGERY | SUPPORT | HEPATOCELLULAR-CARCINOMA | VOLUME | PORTAL-VEIN EMBOLIZATION | RISK | HEPATIC RESECTION | Liver Failure - etiology | Liver Function Tests | Predictive Value of Tests | Postoperative Complications - etiology | Liver Failure - mortality | Prospective Studies | Humans | Middle Aged | Prothrombin Time | Logistic Models | Male | Treatment Outcome | Postoperative Complications - mortality | Chi-Square Distribution | Hepatectomy | Liver Diseases - mortality | Female | Liver Diseases - surgery
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