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Acta Neurologica Scandinavica, ISSN 0001-6314, 08/2008, Volume 118, Issue 2, pp. 69 - 86
Journal Article
FASEB Journal, ISSN 0892-6638, 04/2012, Volume 26, Issue 4, pp. 1616 - 1628
Prolonged seizures [status epilepticus (SE)] constitute a neurological emergency that can permanently damage the brain. SE results from a failure of the normal... 
Pharmacoresistance | Temporal lobe epilepsy | Anticonvulsant | ATP | EXTRACELLULAR ATP | temporal lobe epilepsy | MICROGLIAL ACTIVATION | TEMPORAL-LOBE EPILEPSY | GLUTAMATE RELEASE | anticonvulsant | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFICIENT MICE | CELL BIOLOGY | pharmacoresistance | P2X RECEPTOR | BIOLOGY | CENTRAL-NERVOUS-SYSTEM | RAT HIPPOCAMPUS | SYNAPTIC TERMINALS | C-FOS EXPRESSION | Lorazepam - pharmacology | Neuroprotective Agents - therapeutic use | Microglia - metabolism | Seizures - prevention & control | Seizures - drug therapy | Status Epilepticus - chemically induced | Status Epilepticus - drug therapy | Male | Neurons - cytology | Purinergic P2X Receptor Antagonists - pharmacology | Anticonvulsants - pharmacology | Receptors, Purinergic P2X7 - genetics | Seizures - chemically induced | Lorazepam - therapeutic use | Seizures - physiopathology | Neuroprotective Agents - pharmacology | Seizures - pathology | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Neurons - metabolism | Neurons - drug effects | Microglia - cytology | Glutamic Acid - pharmacology | Kainic Acid - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Status Epilepticus - pathology | Anticonvulsants - therapeutic use | Excitatory Amino Acid Agonists - pharmacology | Hippocampus - pathology | Hippocampus - cytology | Purinergic P2X Receptor Agonists - pharmacology | Mice, Knockout | Animals | Receptors, Purinergic P2X7 - metabolism | Status Epilepticus - physiopathology | Mice
Journal Article
Journal Article
Journal Article
Journal of Emergency Medicine, ISSN 0736-4679, 2016, Volume 52, Issue 5, pp. 680 - 683
Journal Article
Acta Pharmacologica Sinica, ISSN 1671-4083, 2018, Volume 40, Issue 5, pp. 571 - 582
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7579, pp. 477 - 483
At least 120 non-olfactory G-protein-coupled receptors in the human genome are 'orphans' for which endogenous ligands are unknown, and many have no selective... 
EXTRACELLULAR ACIDIFICATION | ACTIVATION | COMPLEX | OGR1 | PROTEIN-COUPLED RECEPTOR | MULTIDISCIPLINARY SCIENCES | CAMP ACCUMULATION | SMOOTH-MUSCLE-CELLS | EXPRESSION | CANCER | Anti-Anxiety Agents - metabolism | Lorazepam - pharmacology | Memory - drug effects | Receptors, G-Protein-Coupled - metabolism | Humans | Anti-Anxiety Agents - analysis | Male | Receptors, G-Protein-Coupled - agonists | Lorazepam - analysis | Benzyl Alcohols - pharmacology | HEK293 Cells | Anti-Anxiety Agents - chemistry | Female | Triazines - chemistry | Allosteric Regulation - drug effects | Benzyl Alcohols - chemistry | Triazines - metabolism | Triazines - pharmacology | Lorazepam - metabolism | Anti-Anxiety Agents - pharmacology | Models, Molecular | Drug Discovery | Mice, Knockout | Triazines - analysis | Fear | Animals | Receptors, G-Protein-Coupled - deficiency | Signal Transduction - drug effects | Benzyl Alcohols - analysis | Allosteric Site | Lorazepam - chemistry | Receptors, G-Protein-Coupled - antagonists & inhibitors | Conditioning, Classical | Benzyl Alcohols - metabolism | Ligands | Mice | Receptors, G-Protein-Coupled - chemistry | Physiological aspects | Cell receptors | Identification and classification | Ligands (Biochemistry) | Proteins | Yeast | Rodents | Physiology | Genomes | Kinases | proton-sensing | virtual screening | GPR68 | GPR65 | positive allosteric modulator (PAM) | functional selectivity | allosteric modulator
Journal Article