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by Wang, Q and Yang, YB and Yang, XQ and Miao, CP and Li, YQ and Liu, SX and Luo, N and Ding, ZT and Zhao, LX
PHYTOCHEMISTRY, ISSN 0031-9422, 01/2018, Volume 145, pp. 146 - 152
Eight previously undescribed metabolites including of lovastatin analogues, a pair of diastereoisomers, a cyclopentenone dimer, and three polyketides were... 
Polyketide | Acetylcholinesterase inhibitor | MUTANTS | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Trichocomaceae | Aspergillus terreus | Lovastatin analogues | Inhibitor of HMGR | PLANT SCIENCES
Journal Article
Annals of Hematology, ISSN 0939-5555, 11/2010, Volume 89, Issue 11, pp. 1115 - 1124
Despite many therapeutic regimens introduced recently, chronic lymphocytic leukemia (CLL) is still an incurable disorder. Thus, there is an urgent need to... 
CLL | Medicine & Public Health | Hematology | DNA damage | Simvastatin | Oncology | Apoptosis | Purine analogs | LOVASTATIN | COA REDUCTASE INHIBITORS | NUCLEOSIDE ANALOGS | STATIN USE | MALIGNANT-CELL | PROLIFERATION | INDUCE APOPTOSIS | COMBINATION | MYELOMA CELLS | V-H GENES | HEMATOLOGY | Prognosis | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Simvastatin - pharmacology | DNA-Binding Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | ZAP-70 Protein-Tyrosine Kinase - metabolism | Antineoplastic Agents - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Tumor Suppressor Proteins - metabolism | Purines - pharmacology | Tumor Cells, Cultured - drug effects | Cell Cycle Proteins - metabolism | bcl-2-Associated X Protein - metabolism | Vidarabine - analogs & derivatives | Ataxia Telangiectasia Mutated Proteins | Cladribine - pharmacology | Vidarabine - pharmacology | Purines - chemistry | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | ADP-ribosyl Cyclase 1 - metabolism | Enzyme Activation | Histones - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Anticholesteremic Agents - pharmacology | Medical colleges | Oncology, Experimental | Development and progression | Transplantation | Research | Alkaloids | Chronic lymphocytic leukemia | Analysis | DNA | Bone marrow | Cancer | Index Medicus | Original
Journal Article
Natural Product Research, ISSN 1478-6419, 07/2015, Volume 29, Issue 14, pp. 1363 - 1368
A new lovastatin analogue versicorin (1), together with three related compounds, decumbenones A (2) and B (3) and versiol (4), were isolated from mycelial... 
soil fungus | Aspergillus versicolor | secondary metabolites | lovastatin analogue | CHEMISTRY, MEDICINAL | CHEMISTRY, APPLIED | Gram-Negative Bacteria | Humans | Aspergillus - chemistry | Cell Line, Tumor | Lovastatin - analogs & derivatives | Molecular Structure | Gram-Positive Bacteria
Journal Article
Journal Article
Magnetic Resonance in Chemistry, ISSN 0749-1581, 03/2011, Volume 49, Issue 3, pp. 129 - 131
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2004, Volume 24, Issue 8, pp. 1454 - 1459
OBJECTIVE—Neural apoptosis-regulated convertase (NARC)-1 is the newest member of the proprotein convertase family implicated in the cleavage of a variety of... 
HepG2 | QPCR | Primary hepatocytes | Cholesterol | SRE | CELLS | ELEMENT-BINDING PROTEIN-2 | primary hepatocytes | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | LOW-DENSITY-LIPOPROTEIN | NUCLEAR RECEPTOR LXR | TARGET GENES | PATHWAY | LIVER | cholesterol | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | Consensus Sequence | Lovastatin - pharmacology | Species Specificity | Humans | Regulatory Sequences, Nucleic Acid | Homeostasis | Lovastatin - analogs & derivatives | Hepatocytes - metabolism | Simvastatin - pharmacology | Promoter Regions, Genetic - genetics | Quinolines - pharmacology | RNA, Messenger - biosynthesis | Cell Line - drug effects | Base Sequence | Liver X Receptors | Serine Endopeptidases - genetics | Orphan Nuclear Receptors | Proprotein Convertases | Sp1 Transcription Factor - physiology | Hepatocytes - drug effects | Heptanoic Acids - pharmacology | Tretinoin - pharmacology | Mevalonic Acid - pharmacology | Cell Line - metabolism | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Serine Endopeptidases - biosynthesis | Receptors, Cytoplasmic and Nuclear - drug effects | Rats | Hydroxymethylglutaryl CoA Reductases - physiology | Reverse Transcriptase Polymerase Chain Reaction | Hydroxycholesterols - pharmacology | Sequence Homology, Nucleic Acid | Gene Expression Regulation - drug effects | Mevalonic Acid - analogs & derivatives | Atorvastatin Calcium | Pyrroles - pharmacology | Sequence Alignment | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Cholesterol - pharmacology | Mice | Pyridines - pharmacology | Cholesterol - biosynthesis | Sterol Regulatory Element Binding Protein 2 | Proprotein Convertase 9
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2012, Volume 14, Issue 3, pp. 249 - 256
Journal Article