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1. Full Text Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178
by Phainuphong, Patima and Rukachaisirikul, Vatcharin and Saithong, Saowanit and Phongpaichit, Souwalak and Bowornwiriyapan, Kawitsara and Muanprasat, Chatchai and Srimaroeng, Chutima and Duangjai, Acharaporn and Sakayaroj, Jariya
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 06/2016, Volume 79, Issue 6, pp. 1500 - 1507
Lovastatin - pharmacology | Soil Microbiology | Humans | KB Cells | Molecular Conformation | Aspergillus - chemistry | Lovastatin - chemistry | Cercopithecus aethiops | Crystallography, X-Ray | Lovastatin - analogs & derivatives | Plasmodium falciparum - drug effects | Thailand | Mycobacterium scrofulaceum - drug effects | Microbial Sensitivity Tests | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Lovastatin - isolation & purification | Inhibitory Concentration 50 | Nuclear Magnetic Resonance, Biomolecular | Vero Cells | Drug Screening Assays, Antitumor | Index Medicus
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2. Full Text Lovastatin analogues and other metabolites from soil-derived Aspergillus terreus YIM PH30711
by Wang, Qiang and Yang, Ya-Bin and Yang, Xue-Qiong and Miao, Cui-Ping and Li, Yi-Qing and Liu, Shi-Xi and Luo, Na and Ding, Zhong-Tao and Zhao, Li-Xing
Phytochemistry (Oxford), ISSN 0031-9422, 01/2018, Volume 145, pp. 146 - 152
Polyketide | Trichocomaceae | Acetylcholinesterase inhibitor | Aspergillus terreus | Lovastatin analogues | Inhibitor of HMGR | Cell Line | Cell Survival - drug effects | Nitric Oxide - biosynthesis | Enzyme Inhibitors - metabolism | Lovastatin - pharmacology | Nitric Oxide - antagonists & inhibitors | Stereoisomerism | Acyl Coenzyme A - antagonists & inhibitors | Humans | Aspergillus - chemistry | Enzyme Inhibitors - pharmacology | Lovastatin - metabolism | Lovastatin - analogs & derivatives | Structure-Activity Relationship | Dose-Response Relationship, Drug | Macrophages - metabolism | Animals | Enzyme Inhibitors - chemistry | Macrophages - drug effects | Mice | Molecular Structure | Erythrocytes - enzymology | Acyl Coenzyme A - metabolism | Acetylcholinesterase - metabolism | Metabolites | Diastereomers | Analysis | Acrylic acid | Lovastatin | Explosives | Antilipemic agents | Index Medicus
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3. Full Text Highly sensitive strategy for identification of trace chemicals in complex matrix: Application to analysis of monacolin analogues in monascus-fermented rice product
by Li, Meng-Ning and Li, Chao-Ran and Gao, Wen and Li, Ping and Yang, Hua
Analytica chimica acta, ISSN 0003-2670, 08/2017, Volume 982, pp. 156 - 167
High performance liquid chromatography-Chip | Trace monacolin | Lovastatin | Multi-step filtering | Identification | Mass spectrometry | Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Tandem Mass Spectrometry | Oryza - chemistry | Chromatography, High Pressure Liquid | Fermented Foods - analysis | Monascus | Naphthalenes - analysis | High performance liquid chromatography | Databases | Filtration | Feature extraction | Data processing | Strategy | Liquid chromatography | High-performance liquid chromatography | Data bases | Chemicals | Index Medicus
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4. Full Text Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
by Hergenreider, E and Heydt, S and Treguer, K and Boettger, T and Horrevoets, A.J.G and Zeiher, A.M and Scheffer, M.P and Frangakis, A.S and Yin, X.K and Mayr, M and Braun, T and Urbich, C and Boon, R.A and Dimmeler, S
Nature cell biology, ISSN 1465-7392, 02/2012, Volume 14, Issue 3, pp. 249 - 256
MicroRNAs/genetics | Coculture Techniques | Humans | Signal Transduction/genetics | Cells, Cultured | Aorta/metabolism | Exosomes/metabolism | Stress, Mechanical | Apolipoproteins E/deficiency | Atherosclerosis/genetics | Microscopy, Electron | Reverse Transcriptase Polymerase Chain Reaction | Endothelial Cells/cytology | Mice, Knockout | Lovastatin/analogs & derivatives | Microscopy, Confocal | Human Umbilical Vein Endothelial Cells/cytology | Animals | Transfection | Myocytes, Smooth Muscle/cytology | Mice | Kruppel-Like Transcription Factors/genetics | Gene Expression Regulation/drug effects | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Exosomes - metabolism | Apolipoproteins E - deficiency | Human Umbilical Vein Endothelial Cells - metabolism | Lovastatin - pharmacology | Atherosclerosis - genetics | Endothelial Cells - transplantation | MicroRNAs - metabolism | Lovastatin - analogs & derivatives | Aorta - metabolism | Kruppel-Like Transcription Factors - metabolism | Human Umbilical Vein Endothelial Cells - cytology | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Exosomes - ultrastructure | Atherosclerosis - pathology | Exosomes - transplantation | Endothelial Cells - metabolism | Signal Transduction - genetics | Atherosclerosis - metabolism | Aorta - pathology | Gene Expression Regulation - drug effects | Endothelial Cells - cytology | Apolipoproteins E - genetics | MicroRNAs - genetics | Kruppel-Like Transcription Factors - genetics | Transcription factors | MicroRNA | Atherosclerosis | Physiological aspects | Genetic aspects | Research | Gene expression | Risk factors | Index Medicus
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5. Full Text The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro
by Mitrofan, Laura M and Pelkonen, Jukka and Mönkkönen, Jukka
Bone (New York, N.Y.), ISSN 8756-3282, 2009, Volume 45, Issue 6, pp. 1153 - 1160
Orthopedics | Resistance | Zoledronic acid | Mass spectrometry | Bisphosphonate-induced ATP analog | Apoptosis | Cancer | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Medical sciences | Pharmacology. Drug treatments | Bones, joints and connective tissue. Antiinflammatory agents | Diterpenes - pharmacology | Lovastatin - pharmacology | Apoptosis - drug effects | Humans | Imidazoles - pharmacology | Membrane Potential, Mitochondrial - drug effects | Adenosine Triphosphate - analogs & derivatives | Adenosine Triphosphate - pharmacology | Cell Line, Tumor | Organophosphorus Compounds - pharmacology | Neoplasms - pathology | Diphosphonates - pharmacology | Drug Resistance, Neoplasm - drug effects | Hemiterpenes - pharmacology | Phosphates | Enzymes | Cell research | Metastasis | Analysis | Diphosphonates | Pharmacy | Cancer cells | Physiological aspects | Universities and colleges | Index Medicus
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6. Full Text Molecularly imprinted membranes for the recognition of lovastatin acid in aqueous medium by a template analogue imprinting strategy
by Wang, Xue-Jun and Xu, Zhen-Liang and Feng, Jian-Li and Bing, Nai-Ci and Yang, Zuo-Guo
Journal of membrane science, ISSN 0376-7388, 2008, Volume 313, Issue 1, pp. 97 - 105
Lovastatin | Molecular recognition in water | Molecularly imprinted membrane | Dummy template | Template analogue imprinting | Engineering | Physical Sciences | Engineering, Chemical | Polymer Science | Technology | Science & Technology | Ethylene glycol | Polyvinylidene fluoride | Hydrogen | Analysis | Nitriles | Antilipemic agents
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7. Full Text Versicorin, a new lovastatin analogue from the fungus Aspergillus versicolor SC0156
by Fu, Ying and Wu, Ping and Xue, Jinghua and Wei, Xiaoyi and Li, Hanxiang
Natural product research, ISSN 1478-6419, 07/2015, Volume 29, Issue 14, pp. 1363 - 1368
soil fungus | Aspergillus versicolor | secondary metabolites | lovastatin analogue | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Gram-Negative Bacteria | Humans | Aspergillus - chemistry | Cell Line, Tumor | Lovastatin - analogs & derivatives | Molecular Structure | Gram-Positive Bacteria | Index Medicus
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8. Full Text Cross-talk between the Cytosolic Mevalonate and the Plastidial Methylerythritol Phosphate Pathways in Tobacco Bright Yellow-2 Cells
by Andréa Hemmerlin and Jean-François Hoeffler and Odile Meyer and Denis Tritsch and Isabelle A. Kagan and Catherine Grosdemange-Billiard and Michel Rohmer and Thomas J. Bach
The Journal of biological chemistry, ISSN 0021-9258, 07/2003, Volume 278, Issue 29, pp. 26666 - 26676
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Xylulose - pharmacology | Erythritol - analogs & derivatives | Lovastatin - pharmacology | Signal Transduction | Fosfomycin - pharmacology | Tobacco - metabolism | Tobacco - drug effects | Plastoquinone - metabolism | Mevalonic Acid - metabolism | Phytosterols - biosynthesis | Tobacco - cytology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Sugar Phosphates - metabolism | Hydroxymethylglutaryl CoA Reductases - metabolism | Cytosol - metabolism | Plastids - metabolism | Erythritol - metabolism | Fosfomycin - analogs & derivatives | Xylulose - analogs & derivatives | Index Medicus
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9. Full Text Structure elucidation and complete NMR spectral assignment of an unusual aromatic monacolin analog from Monascus purpureus‐fermented rice
by Liu, Ming‐Tao and Li, Jin‐Jie and Shang, Xiao‐Ya and Li, Shuai and Li, Ling‐Ling and Luan, Na and Jin, Zong‐Lian
Magnetic resonance in chemistry, ISSN 0749-1581, 03/2011, Volume 49, Issue 3, pp. 129 - 131
13C | NMR | Monascus purpureus‐fermented rice | monacolin analog | 2D NMR | 1H | Monascus purpureus-fermented rice | Spectroscopy | Physical Sciences | Chemistry | Technology | Chemistry, Multidisciplinary | Chemistry, Physical | Science & Technology | Pyrones - chemistry | Magnetic Resonance Spectroscopy | Tetrahydronaphthalenes - chemistry | Lovastatin - chemistry | Anticholesteremic Agents - chemistry | Oryza - chemistry | Lovastatin - analogs & derivatives | Molecular Structure | Monascus - chemistry | Index Medicus
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10. Full Text Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis
by Bentinger, Magnus and Kania, Magdalena and Danikiewicz, Witold and Kaczorowska, Ewa and Wojcik, Jacek and Brismar, Kerstin and Dallner, Gustav and Chojnacki, Tadeusz and Swiezewska, Ewa and Tekle, Michael
Biochimica et biophysica acta. Molecular and cell biology of lipids, ISSN 1388-1981, 07/2014, Volume 1841, Issue 7, pp. 977 - 986
Cholesterol inhibition | Coenzyme Q induction | Squalene epoxides | Mevalonate pathway | Dolichol | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Diabetes Mellitus, Experimental - drug therapy | Lovastatin - pharmacology | Rats, Wistar | Humans | Male | Organophosphorus Compounds - metabolism | Squalene - analogs & derivatives | Squalene - metabolism | Ubiquinone - biosynthesis | Hemiterpenes - metabolism | Risedronate Sodium | Diabetes Mellitus, Experimental - metabolism | Etidronic Acid - analogs & derivatives | Mevalonic Acid - pharmacology | Cholesterol - analogs & derivatives | Tricarboxylic Acids - pharmacology | Mice, Inbred C57BL | Ubiquinone - analogs & derivatives | Rats | Hep G2 Cells | Mice, Knockout | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Etidronic Acid - pharmacology | Squalene - pharmacology | Diabetes Mellitus, Experimental - pathology | Mice | Cholesterol - biosynthesis | Blood cholesterol | Enzymes | Epoxy resins
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11. Full Text Editor's Highlight: Evaluation of a Microelectrode Array-Based Assay for Neural Network Ontogeny Using Training Set Chemicals
by Brown, Jasmine P and Hall, Diana and Frank, Christopher L and Wallace, Kathleen and Mundy, William R and Shafer, Timothy J
Toxicological sciences, ISSN 1096-6080, 11/2016, Volume 154, Issue 1, pp. 126 - 139
Life Sciences & Biomedicine | Toxicology | Science & Technology | Loperamide | Microelectrodes | Kainic Acid - analogs & derivatives | Rats | Lovastatin - analogs & derivatives | Nerve Net - drug effects | Maleimides | Animals | Acetaminophen | Vanadates | Toxicity Tests - methods | Indoles | Primary Cell Culture | Neurons - drug effects | Index Medicus
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