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Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 12/2013, Volume 49, Issue 6, pp. 1009 - 1018
Journal Article
Journal Article
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 03/2016, Volume 72, pp. 55 - 62
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3490 - 3503
Serotonin is a critical regulator of bone mass, fulfilling different functions depending on its site of synthesis. Brain-derived serotonin promotes osteoblast... 
MEDICINE, RESEARCH & EXPERIMENTAL | OSTEOBLAST | OXIDATIVE STRESS | PROTEIN | SIGNALING PATHWAY | PLATELET SEROTONIN | MASS | CRE RECOMBINASE | EXPRESSION | FORKHEAD TRANSCRIPTION FACTORS | TRANSGENIC MICE | Low Density Lipoprotein Receptor-Related Protein-5 - physiology | Serotonin - physiology | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Osteogenesis - physiology | Bone Remodeling - physiology | Forkhead Transcription Factors - physiology | Insulin-Like Growth Factor I - genetics | Serotonin - pharmacology | Serotonin - blood | Receptor, Serotonin, 5-HT1B - deficiency | Receptor, Serotonin, 5-HT1B - genetics | Transcription, Genetic | Osteoblasts - cytology | Forkhead Transcription Factors - deficiency | Genes, Reporter | Promoter Regions, Genetic | Cells, Cultured - drug effects | Stress, Physiological - genetics | Osteoblasts - drug effects | Osteoblasts - physiology | Gene Expression Regulation | Genotype | Receptor, Serotonin, 5-HT1B - physiology | Forkhead Transcription Factors - genetics | Organ Specificity | Cyclic AMP Response Element-Binding Protein - physiology | Low Density Lipoprotein Receptor-Related Protein-5 - deficiency | Cell Division - drug effects | Animals | MAP Kinase Signaling System - drug effects | Homeostasis - physiology | Duodenum - secretion | Forkhead Box Protein O1 | Mice | Activating Transcription Factor 4 - physiology | Blood-Brain Barrier | Serotonin | Cyclic adenosine monophosphate response element-binding protein | Physiological aspects | Bones | Research | Osteoblasts | Density | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 04/2015, Volume 19, Issue 4, pp. 770 - 777
Low‐density lipoprotein receptor‐related protein 5 ( LRP 5) is a member of the LDLR family that orchestrates cholesterol homoeostasis. The role of LRP 5 and... 
atherosclerosis | plasma cholesterol | macrophages | LRP | 5 | canonical Wnt signalling | LRP5 | Macrophages | Canonical Wnt signalling | Plasma cholesterol | Atherosclerosis | MEDICINE, RESEARCH & EXPERIMENTAL | LDL-CHOLESTEROL | ACTIVATION | RECEPTOR-RELATED PROTEIN | LOW-DENSITY-LIPOPROTEIN | MUSCLE-CELL PROLIFERATION | BETA-CATENIN | APOLIPOPROTEIN-E | CELL BIOLOGY | CHOLESTEROL-METABOLISM | EXPRESSION | Immunohistochemistry | Dyslipidemias - genetics | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Diet, High-Fat - adverse effects | Aorta - metabolism | Dyslipidemias - blood | Lipids - blood | Tumor Suppressor Proteins - genetics | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Dyslipidemias - etiology | Receptors, LDL - genetics | Gene Expression | Hypercholesterolemia - blood | Down-Regulation | Mice, Inbred C57BL | Reverse Transcriptase Polymerase Chain Reaction | Low Density Lipoprotein Receptor-Related Protein-5 - deficiency | beta Catenin - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Wnt Signaling Pathway - genetics | Hypercholesterolemia - etiology | Hypercholesterolemia - genetics | Lipids - analysis | Cholesterol, Dietary - adverse effects | Proteins | Hypercholesterolemia | Lipids | Gene expression | Rodents | Cholesterol | Index Medicus | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, pp. e30203 - e30203
Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy... 
CELLS | NORRIE-DISEASE | ANGIOGENESIS | VASCULATURE | GROWTH | BIOLOGY | RETINOPATHY | MUTATIONS | MODEL | FAMILIAL EXUDATIVE VITREORETINOPATHY | BLOOD-BRAIN-BARRIER | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Retina - metabolism | Retina - growth & development | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Profiling | Wnt Proteins - genetics | Gene Expression Regulation, Developmental | Eye Proteins - genetics | Dishevelled Proteins | Disease Models, Animal | Retinal Vessels - metabolism | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Low Density Lipoprotein Receptor-Related Protein-5 - deficiency | Nerve Tissue Proteins - genetics | Amino Acid Transport Systems, Neutral - genetics | Mice, Knockout | Carrier Proteins - genetics | Vitreoretinopathy, Proliferative - genetics | Animals | Frizzled Receptors - genetics | Wnt Signaling Pathway - genetics | Retinal Vessels - growth & development | Adaptor Proteins, Signal Transducing - genetics | Mice | Medical research | RNA | Low density lipoproteins | Analysis | Genes | Medicine, Experimental | Eye diseases | Permeability | Gene expression | Oxidative stress | Diabetic retinopathy | Wnt protein | Ontology | Pathogenesis | Lipid peroxidation | Amino acids | Retina | Medical schools | Eye | Macular degeneration | Proteins | Morphogenesis | Angiogenesis | Rodents | Cell adhesion | LRP5 protein | Growth factors | Cell division | Blood vessels | Ribonucleic acid--RNA | Patients | Children & youth | Familial exudative vitreoretinopathy | DNA microarrays | Molecular modelling | Plasma membranes | Stem cells | Receptor density | Ligands | Hypoxia | Exudation | Diabetes | Mutation | Transporter | Index Medicus | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e103250 - e103250
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 08/2015, Volume 93, Issue 7, pp. 653 - 661
Inflammation is triggered after invasion or injury to restore homeostasis. Although the activation of Wnt/β‐catenin signaling is one of the first molecular... 
TUMOR-NECROSIS-FACTOR | B-CELL | TRANSENDOTHELIAL MIGRATION | ENDOTHELIAL-CELLS | PLANT STEROLS | GENE-TRANSFER | IMMUNOLOGY | BETA-CATENIN | INFLAMMATORY CYTOKINE | T-CELLS | DENSITY-LIPOPROTEIN RECEPTOR | CELL BIOLOGY | Hypercholesterolemia - diet therapy | Low Density Lipoprotein Receptor-Related Protein-5 - physiology | RNA, Small Interfering - genetics | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Cholesterol, Dietary - toxicity | Lipoproteins - genetics | Atherosclerosis - genetics | Cholesterol - blood | Humans | Aortic Diseases - therapy | Monocytes - metabolism | Aorta - metabolism | Jejunum - metabolism | RNA, Messenger - biosynthesis | ATP-Binding Cassette Transporters - genetics | Atherosclerosis - therapy | RNA Interference | Phytosterols - therapeutic use | Wnt Signaling Pathway | Aortic Diseases - pathology | Atherosclerosis - pathology | Hypercholesterolemia - blood | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Low Density Lipoprotein Receptor-Related Protein-5 - deficiency | ATP-Binding Cassette Transporters - biosynthesis | Aorta - pathology | Lipoproteins - biosynthesis | Aortic Diseases - genetics | Macrophages - metabolism | Animals | Spleen - metabolism | Cholesterol, HDL - blood | ATP Binding Cassette Transporter, Sub-Family G, Member 8 | Mice | Leukocytes - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 5 | Index Medicus
Journal Article