X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
lu af21934 (8) 8
animals (5) 5
index medicus (5) 5
male (5) 5
neurosciences (5) 5
pharmacology & pharmacy (5) 5
anilides - pharmacology (4) 4
cyclohexanecarboxylic acids - pharmacology (4) 4
dose-response relationship, drug (4) 4
glutamate (4) 4
rats (4) 4
agonist (3) 3
disease models, animal (3) 3
electrophysiology (3) 3
excitatory postsynaptic potentials - drug effects (3) 3
metabotropic glutamate receptors (3) 3
mice (3) 3
pharmacological characterization (3) 3
rat (3) 3
schizophrenia (3) 3
[ sdv.bc ] life sciences [q-bio]/cellular biology (2) 2
[sdv.bc]life sciences [q-bio]/cellular biology (2) 2
allosteric regulation (2) 2
allosteric regulation - physiology (2) 2
analysis (2) 2
basal ganglia (2) 2
brain - drug effects (2) 2
cellular biology (2) 2
chemistry, medicinal (2) 2
excitatory amino acid agents - pharmacology (2) 2
gaba (2) 2
haloperidol (2) 2
haloperidol - pharmacology (2) 2
high-frequency stimulation (2) 2
l-dopa (2) 2
life sciences (2) 2
lu af32615 (2) 2
mglu (2) 2
mglu receptors (2) 2
mice, inbred c57bl (2) 2
motor activity - drug effects (2) 2
oxidopamine (2) 2
parkinsons-disease treatment (2) 2
positive allosteric modulation (2) 2
rats, wistar (2) 2
receptors, metabotropic glutamate - agonists (2) 2
receptors, metabotropic glutamate - metabolism (2) 2
receptors, metabotropic glutamate - physiology (2) 2
striatum (2) 2
synaptic transmission - drug effects (2) 2
synaptic transmission - physiology (2) 2
-3,4-dcpg (1) 1
6-hydroxydopamine (1) 1
acetanilides - chemistry (1) 1
acetanilides - pharmacology (1) 1
acpt-i (1) 1
activation (1) 1
adx71743 (1) 1
agonist amn082 (1) 1
akinesia (1) 1
allosteric (1) 1
allosteric modulator (1) 1
allosteric regulation - drug effects (1) 1
amino acid transport system x-ag - antagonists & inhibitors (1) 1
amino acid transport system x-ag - metabolism (1) 1
amino acids (1) 1
aminobutyrates (1) 1
aminobutyrates - agonists (1) 1
aminobutyrates - pharmacology (1) 1
aminobutyrates - therapeutic use (1) 1
amphetamine (1) 1
amygdala plasticity (1) 1
anilides (1) 1
anilides - pharmacokinetics (1) 1
anilides - therapeutic use (1) 1
animal-models (1) 1
antagonist (1) 1
anti-anxiety agents - pharmacology (1) 1
anticipatory anxiety (1) 1
antidepressive agents - pharmacology (1) 1
antiparkinson agents - pharmacology (1) 1
antipsychotic (1) 1
antipsychotic agents - pharmacology (1) 1
anxiety (1) 1
arrive guidelines (1) 1
behavior, animal - drug effects (1) 1
benzoates - pharmacology (1) 1
biochemistry & molecular biology (1) 1
body-temperature (1) 1
brain - metabolism (1) 1
brain - physiopathology (1) 1
calcium - metabolism (1) 1
catalepsy (1) 1
catalepsy - chemically induced (1) 1
catalepsy - drug therapy (1) 1
central-nervous-system (1) 1
cerebral cortex - drug effects (1) 1
cerebral cortex - physiopathology (1) 1
cho cells (1) 1
chromosome 3 (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Neuropharmacology, ISSN 0028-3908, 03/2013, Volume 66, pp. 225 - 235
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 08/2013, Volume 169, Issue 8, pp. 1824 - 1839
BACKGROUND AND PURPOSE Because agonists at metabotropic glutamate receptors exert beneficial effects in schizophrenia, we have assessed the actions of Lu... 
SOCIAL-ISOLATION | mGlu receptors | Lu AF21934 | PHARMACOLOGICAL CHARACTERIZATION | positive allosteric modulation | PARKINSONS-DISEASE TREATMENT | INDUCED STEREOTYPED BEHAVIOR | schizophrenia | ARRIVE GUIDELINES | PREFRONTAL CORTEX | Lu AF32615 | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | WORKING-MEMORY | AGONIST
Journal Article
FRONTIERS IN MOLECULAR NEUROSCIENCE, ISSN 1662-5099, 09/2018, Volume 11
The data concerning antipsychotic-like activity of negative allosteric modulators (NAMs)/antagonists of mGlu(7) receptors are limited. The only available... 
RAT | negative allosteric modulators | DISORDERS | METABOTROPIC GLUTAMATE RECEPTORS | schizophrenia | FORCED SWIMMING TEST | NEUROSCIENCES | IN-VITRO | LU AF21934 | MMPIP | metabotropic glutamate receptor 7 | DISEASE | antipsychotic | CENTRAL-NERVOUS-SYSTEM | MICE | ADX71743
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2013, Volume 66, pp. 158 - 169
Group III metabotropic glutamate (mGlu) receptors are localized in presynaptic terminals within basal ganglia (BG) circuitry that become hyperactive due to... 
Striatum | Basal ganglia | Akinesia | Rat | Lu AF21934 | l-DOPA-induced dyskinesia | Electrophysiology | HIGH-FREQUENCY STIMULATION | NEUROLOGICAL DISEASES | NEUROSCIENCES | RAT MODEL | STRIATAL SYNAPTIC PLASTICITY | MEDIATED MODULATION | SUBTHALAMIC NUCLEUS | UNILATERAL 6-HYDROXYDOPAMINE LESIONS | PHARMACOLOGY & PHARMACY | DEEP BRAIN-STIMULATION | L-DOPA-induced dyskinesia | MOLECULAR-MECHANISMS | Anilides - therapeutic use | Catalepsy - drug therapy | Synaptic Transmission - physiology | Excitatory Amino Acid Agonists - therapeutic use | Receptors, Metabotropic Glutamate - physiology | Male | Aminobutyrates - pharmacology | Anilides - pharmacokinetics | Parkinson Disease - drug therapy | Oxidopamine | Aminobutyrates - therapeutic use | Excitatory Postsynaptic Potentials - drug effects | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Haloperidol - antagonists & inhibitors | Allosteric Regulation - physiology | Dyskinesia, Drug-Induced - drug therapy | Catalepsy - chemically induced | Synaptic Transmission - drug effects | Haloperidol - pharmacology | Disease Models, Animal | Allosteric Regulation - drug effects | Aminobutyrates - agonists | Levodopa - pharmacology | Cyclohexanecarboxylic Acids - therapeutic use | Phosphinic Acids - agonists | Levodopa - therapeutic use | Phosphinic Acids - therapeutic use | Rats | Excitatory Amino Acid Agonists - pharmacology | Rats, Sprague-Dawley | Drug Synergism | Animals | Cyclohexanecarboxylic Acids - pharmacology | Levodopa - adverse effects | Phosphinic Acids - pharmacology | Anilides - pharmacology | Excitatory Amino Acid Agonists - pharmacokinetics | Cyclohexanecarboxylic Acids - pharmacokinetics | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Physiological aspects | Phenols | Amino acids | Parkinson's disease | Glutamate | Drug therapy | 6-Hydroxydopamine | Phosphinic Acids | Excitatory Amino Acid Agonists | Allosteric Regulation | Catalepsy | Haloperidol | Aminobutyrates | Cellular Biology | Synaptic Transmission | Receptors, Metabotropic Glutamate | Parkinson Disease | Anilides | Life Sciences | Excitatory Postsynaptic Potentials | Cyclohexanecarboxylic Acids | Dyskinesia, Drug-Induced | Levodopa
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2014, Volume 85, pp. 166 - 177
Metabotropic glutamate 4 (mGlu4) receptor is a promising target for the treatment of motor deficits in Parkinson's disease (PD). This is due in part to its... 
Electrophysiology | Globus pallidus | Striatum | Basal ganglia | Rat | Lu AF21934 | GLOBUS-PALLIDUS | METABOTROPIC GLUTAMATE RECEPTORS | PARKINSONS-DISEASE TREATMENT | HIGH-FREQUENCY STIMULATION | SUBTHALAMIC NUCLEUS NEURONS | NEUROSCIENCES | RAT STRIATAL NEURONS | ENTOPEDUNCULAR NUCLEUS | L-DOPA | PHARMACOLOGY & PHARMACY | PURKINJE-CELL SYNAPSES | Parkinsonian Disorders | Antiparkinson Agents - pharmacology | Synaptic Transmission - physiology | Rats, Wistar | Male | Receptors, Metabotropic Glutamate - metabolism | Oxidopamine | Cerebral Cortex - physiopathology | Amino Acid Transport System X-AG - metabolism | Excitatory Amino Acid Agents - pharmacology | Synaptic Transmission - drug effects | Cerebral Cortex - drug effects | Globus Pallidus - physiopathology | Haloperidol - pharmacology | Disease Models, Animal | Synapses - drug effects | Corpus Striatum - physiopathology | Synapses - physiology | Tissue Culture Techniques | Brain - physiopathology | Brain - drug effects | Globus Pallidus - drug effects | Amino Acid Transport System X-AG - antagonists & inhibitors | Animals | Cyclohexanecarboxylic Acids - pharmacology | Dopamine Antagonists - pharmacology | Anilides - pharmacology | Corpus Striatum - drug effects | Glutamic Acid - metabolism | GABA | Haloperidol | Glutamate | Analysis | Life Sciences | Cellular Biology
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 12/2014, Volume 5, Issue 12, pp. 1221 - 1237
Metabotropic glutamate receptor 7 (mGlu(7)) is a member of the group III mGlu receptors (mGlus), encompassed by mGlu(4), mGlu(6), mGlu(7), and mGlu(8). mGlu(7)... 
Electrophysiology | Allosteric modulator | Hippocampus | Metabotropic glutamate receptor | CHEMISTRY, MEDICINAL | hippocampus | metabotropic glutamate receptor | AMYGDALA PLASTICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | PROBE-DEPENDENCE | CHROMOSOME 3 | PHARMACOLOGICAL MODULATION | RODENT MODELS | LU AF21934 | electrophysiology | IN-VIVO | L-DOPA | AGONIST AMN082 | PARKINSONS-DISEASE | Propionates - pharmacology | Glycine - analogs & derivatives | Cricetulus | Calcium - metabolism | Humans | Male | Receptors, Metabotropic Glutamate - metabolism | Structure-Activity Relationship | Thallium - metabolism | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Excitatory Amino Acid Agents - chemistry | Dose-Response Relationship, Drug | Transfection | Receptors, Metabotropic Glutamate - genetics | Excitatory Amino Acid Agents - pharmacology | HEK293 Cells | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Picolinic Acids - chemistry | CHO Cells | Picolinic Acids - pharmacology | Acetanilides - pharmacology | Glutamic Acid - pharmacology | Mice, Inbred C57BL | Rats | G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics | Hippocampus - metabolism | Pyrroles - pharmacology | Animals | Glycine - pharmacology | Acetanilides - chemistry | Benzoates - pharmacology | Pyrroles - chemistry | In Vitro Techniques
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.