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FEBS Journal, ISSN 1742-464X, 05/2010, Volume 277, Issue 10, pp. 2268 - 2281
TDP‐43 has recently been described as the major component of the inclusions found in the brain of patients with a variety of neurodegenerative diseases, such... 
microRNAs | miR‐663 | amyotrophic lateral sclerosis | TDP‐43 | let‐7b | Let-7b | Amyotrophic lateral sclerosis | MiR-663 | MicroRNAs | TDP-43 | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYOTROPHIC-LATERAL-SCLEROSIS | FRONTOTEMPORAL LOBAR DEGENERATION | let-7b | STRUCTURAL DETERMINANTS | RNA-BINDING PROTEIN | CELLULAR TOXICITY | miR-663 | EXPRESSION PATTERNS | DOWN-SYNDROME | GENE-EXPRESSION | CFTR EXON-9 | HNRNP A1 | RNA, Small Interfering - genetics | Protein Binding - genetics | Luciferases - metabolism | Gene Expression - genetics | Humans | MicroRNAs - metabolism | RNA, Messenger - metabolism | Luciferases - genetics | DNA-Binding Proteins - metabolism | Protein-Tyrosine Kinases - genetics | Qa-SNARE Proteins - genetics | Vesicle-Associated Membrane Protein 3 - genetics | Recombinant Proteins - metabolism | Base Sequence - genetics | Ribonuclease III - metabolism | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Protein-Serine-Threonine Kinases - genetics | Genes, Reporter - genetics | Up-Regulation - genetics | Recombinant Proteins - genetics | DNA-Binding Proteins - genetics | Down-Regulation - genetics | Epoxide Hydrolases - genetics | Laminin - genetics | Cell Line, Tumor | MicroRNAs - genetics | HeLa Cells | Messenger RNA | Genetically modified organisms | Proteins | Brain | Biochemistry | Ribonucleic acid--RNA | Neurological disorders | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2017, Volume 114, Issue 9, pp. 2343 - 2348
Rotaviruses (RVs) are highly important pathogens that cause severe diarrhea among infants and young children worldwide. The understanding of the molecular... 
Vaccine | Reporter virus | Rotavirus | Reverse genetics | reverse genetics | NSP1 | PROTEIN | MULTIDISCIPLINARY SCIENCES | reporter virus | INNATE IMMUNE-RESPONSE | VACCINIA VIRUS | BLUETONGUE VIRUS | CLONED CDNA | vaccine | MESSENGER-RNA | rotavirus | RNA-CAPPING ENZYME | SYNTHETIC RNA | EXPRESSION | Luciferases - metabolism | Cricetulus | Humans | Methyltransferases - metabolism | Reverse Genetics - methods | DNA, Complementary - genetics | Methyltransferases - genetics | Multienzyme Complexes - metabolism | Green Fluorescent Proteins - genetics | Orthoreovirus - metabolism | Vaccinia virus - genetics | Viral Proteins - metabolism | Luciferases - genetics | Base Sequence | Nucleotidyltransferases - metabolism | Genes, Reporter | Cell Line | Green Fluorescent Proteins - metabolism | Phosphoric Monoester Hydrolases - genetics | Transduction, Genetic | Vaccinia virus - metabolism | Orthoreovirus - genetics | Orthoreovirus, Mammalian - genetics | Gene Expression Regulation | Viral Nonstructural Proteins - genetics | Viral Proteins - genetics | DNA-Directed RNA Polymerases - genetics | Multienzyme Complexes - genetics | Plasmids - metabolism | Animals | Epithelial Cells - virology | Plasmids - chemistry | Cell Line, Tumor | Nucleotidyltransferases - genetics | Viral Nonstructural Proteins - metabolism | DNA-Directed RNA Polymerases - metabolism | Phosphoric Monoester Hydrolases - metabolism | DNA, Complementary - metabolism | Orthoreovirus, Mammalian - metabolism | Genetic aspects | Gene expression | Health aspects | Rotaviruses | Viruses | Genetics | Microbiology | Pathogenesis | Plasmids | Medical immunity | Index Medicus | Biological Sciences
Journal Article
by French, Juliet D and Ghoussaini, Maya and Edwards, Stacey L and Meyer, Kerstin B and Michailidou, Kyriaki and Ahmed, Shahana and Khan, Sofia and Maranian, Mel J and O’Reilly, Martin and Hillman, Kristine M and Betts, Joshua A and Carroll, Thomas and Bailey, Peter J and Dicks, Ed and Beesley, Jonathan and Tyrer, Jonathan and Maia, Ana-Teresa and Beck, Andrew and Knoblauch, Nicholas W and Chen, Shou-Tung and Chen, Constance and Kraft, Peter and Barnes, Daniel and González-Neira, Anna and Alonso, M. Rosario and Herrero, Daniel and Tessier, Daniel C and Vincent, Daniel and Bacot, Francois and Luccarini, Craig and Baynes, Caroline and Conroy, Don and Dennis, Joe and Bolla, Manjeet K and Wang, Xianshu and Wang, Qin and Hopper, John L and Southey, Melissa C and Schmidt, Marjanka K and Broeks, Annegien and Verhoef, Senno and Cornelissen, Sten and Muir, Kenneth and Lophatananon, Artitaya and Stewart-Brown, Sarah and Siriwanarangsan, Pornthep and Fasching, Peter A and Loehberg, Christian R and Ekici, Arif B and Beckmann, Matthias W and Peto, Julian and dos Santos Silva, Isabel and Johnson, Nichola and Aitken, Zoe and Sawyer, Elinor J and Tomlinson, Ian and Kerin, Michael J and Miller, Nicola and Marme, Frederik and Schneeweiss, Andreas and Sohn, Christof and Burwinkel, Barbara and Guénel, Pascal and Truong, Thérèse and Laurent-Puig, Pierre and Menegaux, Florence and Bojesen, Stig E and Nordestgaard, Børge G and Nielsen, Sune F and Flyger, Henrik and Milne, Roger L and Zamora, M. Pilar and Arias Perez, Jose Ignacio and Benitez, Javier and Anton-Culver, Hoda and Brenner, Hermann and Müller, Heiko and Arndt, Volker and Stegmaier, Christa and Meindl, Alfons and Lichtner, Peter and Schmutzler, Rita K and Engel, Christoph and Brauch, Hiltrud and Hamann, Ute and Justenhoven, Christina and Aaltonen, Kirsimari and Heikkilä, Päivi and Aittomäki, Kristiina and Blomqvist, Carl and Matsuo, Keitaro and Ito, Hidemi and Iwata, Hiroji and Sueta, Aiko and Bogdanova, Natalia V and Antonenkova, Natalia N and Dörk, Thilo and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and ... and KConFab Investigators and GENICA Network and kConFab Investigators
The American Journal of Human Genetics, ISSN 0002-9297, 04/2013, Volume 92, Issue 4, pp. 489 - 503
Journal Article
PLoS Genetics, ISSN 1553-7390, 02/2010, Volume 6, Issue 2, pp. e1000836 - e1000836
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e90528 - e90528
We previously reported that the intronic tagSNP +357G/C in the metastasis suppressor HTPAP is associated with metastasis and prognosis of hepatocellular... 
CANCER-CELLS | SUPPRESSOR | VARIANTS | GENE | MULTIDISCIPLINARY SCIENCES | RISK | CHROMOSOME 8P DELETION | EXPRESSION | ASSOCIATION | Prognosis | Liver Neoplasms - genetics | Carcinoma, Hepatocellular - diagnosis | Neoplasm Invasiveness | Genomics | Humans | Middle Aged | Phosphatidate Phosphatase - metabolism | Male | Phosphatidate Phosphatase - genetics | Promoter Regions, Genetic - genetics | Haplotypes - genetics | Neoplasm Metastasis | Liver Neoplasms - diagnosis | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Female | Liver Neoplasms - pathology | Polymorphism, Single Nucleotide | Transcription, Genetic - genetics | Gene Expression Regulation, Neoplastic - genetics | Carcinoma, Hepatocellular - metabolism | Genetic aspects | Metastasis | Hepatoma | RNA | Luciferase | Cancer | Haplotypes | Transcription | Laboratories | Linkage disequilibrium | Science | Hepatocellular carcinoma | Genomes | Single-nucleotide polymorphism | Multivariate analysis | Western blotting | Metastases | Liver cancer | Education | Hepatology | Surgery | Deoxyribonucleic acid--DNA | Regression analysis | Gene expression | Patients | Promoters | Genetic variance | DNA microarrays | Plasmids | Medical prognosis | Cell lines | Mutation | Genetic testing | Aberration | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2012, Volume 31, Issue 21, pp. 4165 - 4178
The contribution of human subtelomeric DNA and chromatin organization to telomere integrity and chromosome end protection is not yet understood in molecular... 
subtelomere | shelterin | histone | RNA polymerase | telomere | REPEAT-CONTAINING RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | CHROMOSOME | ICF SYNDROME | DYSFUNCTIONAL TELOMERES | HETEROCHROMATIN | GENE-EXPRESSION | EPIGENETIC REGULATION | GENOME-WIDE | POLYMERASE-II | BINDING-SITES | Luciferases - metabolism | Humans | RNA Polymerase II - metabolism | Phosphoproteins - metabolism | Promoter Regions, Genetic - genetics | Chromatin Immunoprecipitation | Neoplasms - genetics | Cell Cycle Proteins - genetics | Transcription, Genetic | Electrophoretic Mobility Shift Assay | Nuclear Proteins - genetics | Real-Time Polymerase Chain Reaction | Repressor Proteins - metabolism | Telomere - genetics | Chromosomal Proteins, Non-Histone - metabolism | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Cells, Cultured | Gene Expression Regulation | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Chromosomal Proteins, Non-Histone - genetics | CCCTC-Binding Factor | Fluorescent Antibody Technique | CpG Islands - genetics | RNA Polymerase II - genetics | Neoplasms - pathology | Chromatin - genetics | Proteins | Chromatin | Molecular biology | DNA damage | Index Medicus
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 09/2008, Volume 16, Issue 9, pp. 1630 - 1636
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e38955 - e38955
Epigenetic silencing is one of the mechanisms leading to inactivation of a tumor suppressor gene, either by DNA methylation or histone modification in a... 
MITOGEN-INDUCIBLE GENE-6 | CELL LUNG-CANCER | SIGNAL | APOPTOSIS | MELANOMA | GROWTH | BIOLOGY | TUMOR-SUPPRESSOR GENE | EGF RECEPTOR | NEGATIVE REGULATOR | DELETION | DNA Modification Methylases - antagonists & inhibitors | Humans | Molecular Sequence Data | DNA Primers - genetics | Promoter Regions, Genetic - genetics | Chromatin Immunoprecipitation | Luciferases | Microarray Analysis | Base Sequence | Tumor Suppressor Proteins - genetics | Plasmids - genetics | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Hydroxamic Acids - pharmacology | Tumor Suppressor Proteins - metabolism | Azacitidine - analogs & derivatives | Reverse Transcriptase Polymerase Chain Reaction | Sequence Analysis, DNA | Blotting, Western | Azacitidine - pharmacology | Epigenesis, Genetic - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | CpG Islands - genetics | Histone Deacetylase Inhibitors - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Epigenetic inheritance | Methyltransferases | Lung cancer | Genes | Melanoma | Genetic aspects | Methylation | Gene expression | Cancer | Drugs | Azacytidine | Biotechnology | Histone deacetylase | Transcription factors | Laboratories | Leukemia | Lung | Oncology | Thyroid gland | Kinases | Inactivation | Cancer therapies | Skin cancer | Proteins | Signal transduction | Negative feedback | Epidermal growth factor | DNA methylation | Trichostatin A | Growth factors | Deoxyribonucleic acid--DNA | Deactivation | Epidermal growth factor receptors | Breast cancer | Tumor cell lines | Inhibitors | Deacetylation | Medical prognosis | Cell lines | Regulatory mechanisms (biology) | Epigenetics | DNA methyltransferase | Tumor suppressor genes | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
by Bojesen, Stig E and Pooley, Karen A and Johnatty, Sharon E and Beesley, Jonathan and Michailidou, Kyriaki and Tyrer, Jonathan P and Edwards, Stacey L and Pickett, Hilda A and Shen, Howard C and Smart, Chanel E and Hillman, Kristine M and Mai, Phuong L and Lawrenson, Kate and Stutz, Michael D and Lu, Yi and Karevan, Rod and Woods, Nicholas and Johnston, Rebecca L and French, Juliet D and Chen, Xiaoqing and Weischer, Maren and Nielsen, Sune F and Maranian, Melanie J and Ghoussaini, Maya and Ahmed, Shahana and Baynes, Caroline and Bolla, Manjeet K and Wang, Qin and Dennis, Joe and McGuffog, Lesley and Barrowdale, Daniel and Lee, Anew and Healey, Sue and Lush, Michael and Tessier, Daniel C and Vincent, Daniel and Bacot, Françis and Vergote, Ignace and Lambrechts, Sanina and Despierre, Evelyn and Risch, Harvey A and González-Neira, Anna and Rossing, Mary Anne and Pita, Guillermo and Doherty, Jennifer A and Alvarez, Nuria and Larson, Melissa C and Fridley, Brooke L and Schoof, Nils and Chang-Claude, Jenny and Cicek, Mine S and Peto, Julian and Kalli, Kimberly R and Broeks, Annegien and Armasu, Sebastian M and Schmidt, Marjanka K and Braaf, Linde M and Winterhoff, Boris and Nevanlinna, Heli and Konecny, Gottfried E and Lambrechts, Diether and Rogmann, Lisa and Guénel, Pascal and Teoman, Attila and Milne, Roger L and Garcia, Joaquin J and Cox, Angela and Shridhar, Vijayalakshmi and Burwinkel, Barbara and Marme, Frederik and Hein, Rebecca and Sawyer, Elinor J and Haiman, Christopher A and Wang-Gohrke, Shan and Anulis, Irene L and Moysich, Kirsten B and Hopper, John L and Odunsi, Kunle and Lindblom, Annika and Giles, Graham G and Brenner, Hermann and Simard, Jacques and Lurie, Galina and Fasching, Peter A and Carney, Michael E and Radice, Paolo and Wilkens, Lynne R and Swerdlow, Anthony and Goodman, Marc T and Brauch, Hiltrud and Garcia-Closas, Montserrat and Hillemanns, Peter and Winqvist, Robert and Dürst, Matthias and Devilee, Peter and Runnebaum, Ingo and Jakubowska, Anna and Lubinski, Jan and Mannermaa, Arto and Butzow, Ralf and ... and Gene Environm Interactimi Breast and Kathleen Cuningham Fdn Consortium and Australian Ovarian Canc Study and Epidemiological Study BRCA1 and Hereditary Breast Ovarian Canc Res and Genetic Modifiers Canc Risk BRCA1 and Australian Canc Study and Swedish Breast Canc Study SWE-BRCA and Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO) and Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and Gene Environment Interaction and Breast Cancer (GENICA) and Swedish Breast Cancer Study (SWE-BRCA) and Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE) and Australian Ovarian Cancer Study and Australian Cancer Study and Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab) and The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and Medicinska fakulteten and Umeå universitet and Institutionen för strålningsvetenskaper
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 4, pp. 371 - 384
Journal Article