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Clinical Orthopaedics and Related Research, ISSN 0009-921X, 6/2015, Volume 473, Issue 6, pp. 1903 - 1912
Journal Article
Spine, ISSN 0362-2436, 04/2013, Volume 38, Issue 7, pp. 581 - 590
Journal Article
Spine, ISSN 0362-2436, 2015, Volume 40, Issue 11, pp. 773 - 782
Study Design. Autophagy-related gene expression and ultrastructural features of autophagy were studied in human discs. Objective. To obtain... 
TNF-α | Disc degeneration | Intervertebral disc | PIM-2 oncogene | p62/SQSTM1 | Proinflammatory cytokines | IL-1β | Autophagy | WIPI49 | NUCLEUS PULPOSUS | intervertebral disc | proinflammatory cytokines | autophagy | TNF-alpha | TISSUE | IL-1 beta | 3-DIMENSIONAL CULTURE | MEDIATED APOPTOSIS | PROTEOGLYCAN | CLINICAL NEUROLOGY | PATHOGENESIS | OXYGEN | BIOENERGETICS | GENE-EXPRESSION | disc degeneration | SENESCENCE | ORTHOPEDICS | Protein-Serine-Threonine Kinases - analysis | RNA-Binding Proteins - genetics | Autophagy-Related Proteins | Interleukin-1beta - pharmacology | Gene Expression - drug effects | Microtubule-Associated Proteins - genetics | Cathepsin B - genetics | Humans | Middle Aged | Apoptosis Regulatory Proteins - analysis | RNA, Messenger - analysis | Infant | Male | Autophagy - drug effects | Membrane Proteins - analysis | Intervertebral Disc Degeneration - metabolism | Cysteine Endopeptidases - analysis | Intervertebral Disc Degeneration - pathology | Young Adult | Sacrum | Ubiquitin-Conjugating Enzymes - analysis | Apoptosis Regulatory Proteins - genetics | Adult | Female | Autophagy - genetics | Ubiquitin-Activating Enzymes - analysis | RNA-Binding Proteins - analysis | Intervertebral Disc Degeneration - genetics | Beclin-1 | Intervertebral Disc - ultrastructure | Ubiquitin-Activating Enzymes - genetics | Microtubule-Associated Proteins - analysis | Membrane Proteins - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Intervertebral Disc - chemistry | Presenilin-1 - genetics | Proto-Oncogene Proteins - genetics | Ubiquitin-Conjugating Enzymes - genetics | Up-Regulation - drug effects | Carrier Proteins - genetics | Tumor Necrosis Factor-alpha - pharmacology | Autophagy-Related Protein 7 | Cysteine Endopeptidases - genetics | Aged | Lumbar Vertebrae
Journal Article
Apoptosis, ISSN 1360-8185, 7/2013, Volume 18, Issue 7, pp. 777 - 785
Degeneration of intervertebral disc (IVD) is mainly a chronic process of excessive destruction of the extracellular matrix (ECM), and also is thought to be the... 
Biochemistry, general | Biomedicine | Cell death | Intervertebral disc | Cancer Research | Oncology | Degeneration | Cell Biology | Virology | REGIONAL-DISTRIBUTION | FAS LIGAND | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN LUMBAR DISC | MEDIATED APOPTOSIS | END-PLATE | CELL BIOLOGY | IN-VITRO | NOTOCHORDAL CELLS | NUCLEUS PULPOSUS CELLS | GENE-EXPRESSION | RNA, Small Interfering - genetics | Transcription Factor CHOP - genetics | Caspase Inhibitors - pharmacology | Low Back Pain - prevention & control | Humans | Extracellular Matrix - metabolism | Stress, Mechanical | Intervertebral Disc Degeneration - metabolism | Intervertebral Disc Degeneration - therapy | Intervertebral Disc Degeneration - pathology | Extracellular Matrix - genetics | Caspases - metabolism | Apoptosis Regulatory Proteins - genetics | Cell Death - drug effects | Intervertebral Disc - pathology | Intervertebral Disc Degeneration - genetics | Signal Transduction | Caspases - genetics | Extracellular Matrix - drug effects | Gene Expression Regulation | Transcription Factor CHOP - antagonists & inhibitors | Intervertebral Disc - metabolism | Apoptosis Regulatory Proteins - metabolism | Animals | Apoptosis Regulatory Proteins - antagonists & inhibitors | Apoptosis Regulatory Proteins - agonists | Intervertebral Disc - drug effects | Transcription Factor CHOP - metabolism | Extracellular Matrix - pathology | RNA, Small Interfering - metabolism | Biochemistry | Health aspects | Backache | Analysis
Journal Article