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Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 2, p. 400
Plumeria rubra Linn of the family Apocynaceae is locally known in Malaysia as "Kemboja". It has been used by local traditional medicine practitioners for the... 
Xanthine oxidase | Phenol | Antioxidant | Flavonoid | Plumeria rubra | antioxidant | OXIDATIVE STRESS | PHENOLIC-COMPOUNDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE-LIVER | OXONATE-INDUCED MICE | FACTOR-KAPPA-B | SERUM | CHEMISTRY, MULTIDISCIPLINARY | GENE-EXPRESSION | phenol | flavonoid | xanthine oxidase | MEDICINAL-PLANTS | LUNG INFLAMMATION | URIC-ACID LEVELS | Phenols - isolation & purification | Plant Extracts - chemistry | Antioxidants - chemistry | Hyperuricemia - pathology | Plant Extracts - pharmacology | Male | Flowers - chemistry | Benzopyrans - chemistry | Citric Acid - chemistry | Biphenyl Compounds - antagonists & inhibitors | Cinnamates - isolation & purification | Picrates - chemistry | Kaempferols - isolation & purification | Anti-Inflammatory Agents - isolation & purification | Uric Acid - blood | Biphenyl Compounds - chemistry | Cinnamates - chemistry | Xanthine Oxidase - antagonists & inhibitors | Xanthine Oxidase - metabolism | Anti-Inflammatory Agents - pharmacology | Apocynaceae - chemistry | Kaempferols - chemistry | Nitric Oxide - antagonists & inhibitors | Rats | Plant Extracts - isolation & purification | Antioxidants - pharmacology | Oxonic Acid - administration & dosage | Benzopyrans - isolation & purification | Rats, Sprague-Dawley | Hydrogen Peroxide - metabolism | Hyperuricemia - drug therapy | Hyperuricemia - blood | Picrates - antagonists & inhibitors | Animals | Anti-Inflammatory Agents - chemistry | Antioxidants - isolation & purification | Uric Acid - antagonists & inhibitors | Citric Acid - isolation & purification | Phenols - chemistry | Flavonoids - isolation & purification | Liquid-Liquid Extraction - methods | Nitric Oxide - metabolism | Flavonoids - chemistry | Hydrogen Peroxide - antagonists & inhibitors | Hyperuricemia - chemically induced | Oxidative stress | Hydrogen peroxide | Toxicity | Liver | Body weight | Arthritis | Flowers | Antioxidants | Fluorescence recovery after photobleaching | Rodents | Chelation | Biocompatibility | Inhibition | Free radicals | Kaempferol | Scavenging | Medical treatment | Chlorogenic acid | Superoxide | Uric acid | Xanthine | Rutin | Citric acid | Acids | Quinic acid | Nitric oxide | Quercetin | Phenols | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e66220 - e66220
Cisplatin is widely used as an antineoplastic drug, but its ototoxic and nephrotoxic side-effects, as well as the inherent or acquired resistance of some... 
HAIR-CELLS | CARBOPLATIN | CHAPERONE-ACTIVITY | CRYSTAL-STRUCTURE | DNA | MULTIDISCIPLINARY SCIENCES | INDUCED OTOTOXICITY | CANCER | MASS-SPECTROMETRY | STATISTICAL-MODEL | CHILDREN | Ribosomal Proteins - chemistry | Adenosine Triphosphatases - isolation & purification | Epithelial Cells - chemistry | Glycoconjugates - chemistry | Antineoplastic Agents - chemical synthesis | Calreticulin - isolation & purification | Membrane Glycoproteins - chemistry | Valosin Containing Protein | Kidney Tubules, Proximal - chemistry | Cell Cycle Proteins - chemistry | Cisplatin - chemistry | HSP90 Heat-Shock Proteins - chemistry | HSP90 Heat-Shock Proteins - isolation & purification | Nonmuscle Myosin Type IIA - chemistry | Epithelial Cells - cytology | Cell Line | Kidney Tubules, Proximal - cytology | Cell Cycle Proteins - isolation & purification | Membrane Glycoproteins - isolation & purification | Cisplatin - analogs & derivatives | Cell Extracts - chemistry | Antineoplastic Agents - chemistry | Glycoconjugates - chemical synthesis | Organ of Corti - chemistry | Calreticulin - chemistry | Nonmuscle Myosin Type IIA - isolation & purification | Ribosomal Proteins - isolation & purification | Animals | Sepharose - chemistry | Organ of Corti - cytology | Protein Binding | Adenosine Triphosphatases - chemistry | Mice | Cisplatin - chemical synthesis | Complications and side effects | Drug interactions | Physiological aspects | Dosage and administration | Research | Binding proteins | Cisplatin | Pediatrics | Oxidative stress | Hsp90 protein | Conjugates | Toxicity | Lung cancer | Cytotoxicity | Selectivity | Proteins | Spectrometry | Calreticulin | Platinum compounds | Platinum | Chlorides | Myosin | Cell cycle | Deoxyribonucleic acid--DNA | Killing | Binding | Gel electrophoresis | Heat shock proteins | Hearing impairment | Side effects | Cochlea | Mutation | Protein interaction | Ototoxicity | Cancer | Apoptosis | Amino groups | Kidney transplantation | Heat shock | Index Medicus | Deoxyribonucleic acid
Journal Article
Small, ISSN 1613-6810, 12/2013, Volume 9, Issue 24, pp. 4221 - 4236
Aberrant signaling of the epidermal growth factor receptor (EGFR) is common to a variety of human cancers and is also found to be over‐expressed in most cases... 
oleyl cysteineamide | biodistribution | paclitaxel‐palmitate | conjugation | PLGA nanoparticles | paclitaxel-palmitate | VITRO | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | CARBON NANOVECTORS | CHEMISTRY, MULTIDISCIPLINARY | FUNCTIONALIZATION | CETUXIMAB | THERAPY IN-VIVO | PROSTATE-CANCER | FATTY-ACID | DOCOSAHEXAENOIC ACID-PACLITAXEL | Surface Plasmon Resonance | Lung Neoplasms - drug therapy | Neoplasm Transplantation | Nanoparticles - chemistry | Area Under Curve | Antibodies - chemistry | Humans | Drug Delivery Systems | Paclitaxel - chemistry | Antibodies, Monoclonal, Humanized - administration & dosage | Palmitates - administration & dosage | Immunotherapy | Surface Properties | Sulfhydryl Compounds - chemistry | Cetuximab | Lactic Acid - chemistry | Cysteine - chemistry | Mice, SCID | Receptor, Epidermal Growth Factor - chemistry | Animals | Polyglycolic Acid - chemistry | Amides - chemistry | Cell Line, Tumor | Mice | Nanoparticles - administration & dosage | Nanotechnology | Antibodies, Monoclonal, Humanized - chemistry | Viral antibodies | Nanoparticles | Epidermal growth factor | Thiols | Paclitaxel | Antibodies | Lung cancer, Non-small cell | Tumors | Medical research | Lung cancer | Index Medicus | Drugs | Effectiveness | Lungs | Indium phosphides | Chemical compounds | Cancer
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2015, Volume 137, Issue 5, pp. 2056 - 2066
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 01/2018, Volume 110, Issue 1, pp. 109 - 120
Background: Cancer-associated fibroblasts (CAFs) are tumor-promoting and correlate with poor survival in many cancers, which has led to their emergence as... 
CELL LUNG-CANCER | PHASE-II TRIAL | OXIDATIVE STRESS | ONCOLOGY | NAB-PACLITAXEL | ACTIVATION PROTEIN | DEPENDENT INVASION | PANCREATIC-CANCER | MONOCLONAL-ANTIBODY | DIFFERENTIATION | STROMAL CELLS | Lung Neoplasms - drug therapy | Up-Regulation | Pyrazoles - therapeutic use | Reactive Oxygen Species - metabolism | Cell Count | Humans | Middle Aged | Male | Oropharyngeal Neoplasms - pathology | Head and Neck Neoplasms - chemistry | RNA Interference | Cancer-Associated Fibroblasts - chemistry | Aged, 80 and over | NADPH Oxidases - genetics | Adenocarcinoma - chemistry | Esophageal Neoplasms - chemistry | Lung Neoplasms - chemistry | NADPH Oxidases - antagonists & inhibitors | Head and Neck Neoplasms - drug therapy | Carcinoma, Squamous Cell - chemistry | Survival Rate | Adenocarcinoma - drug therapy | Disease Progression | Phenotype | Carcinoma, Squamous Cell - drug therapy | Head and Neck Neoplasms - genetics | Mice | Neoplasm Transplantation | Carcinoma, Non-Small-Cell Lung - chemistry | Carcinoma, Squamous Cell - genetics | Colorectal Neoplasms - chemistry | Cell Transdifferentiation - genetics | Myofibroblasts - chemistry | Actins - analysis | Cell Transdifferentiation - drug effects | Adult | Female | Adenocarcinoma - genetics | Cancer-Associated Fibroblasts - physiology | Pyridines - therapeutic use | Lung Neoplasms - genetics | Myofibroblasts - pathology | Carcinoma, Non-Small-Cell Lung - genetics | NADPH Oxidases - analysis | Mouth Neoplasms - chemistry | NADPH Oxidase 4 | Cancer-Associated Fibroblasts - pathology | Animals | Esophageal Neoplasms - genetics | Mouth Neoplasms - pathology | Oropharyngeal Neoplasms - chemistry | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Colorectal Neoplasms - pathology | Esophageal Neoplasms - drug therapy | Index Medicus
Journal Article
Journal Article
ACS Nano, ISSN 1936-0851, 07/2014, Volume 8, Issue 7, pp. 7014 - 7026
Journal Article
Journal Article
Journal Article
Carbohydrate Polymers, ISSN 0144-8617, 01/2019, Volume 204, pp. 142 - 151
The present work investigated the antioxidative, anti-inflammatory and pulmonary protective effects of enzymatic- and acid- hydrolysed mycelia polysaccharides... 
Oudemansiella radicata | Acute lung injury | Antioxidant | Pulmonary protective | Anti-inflammatory | Enzymatic- acid- hydrolysed mycelia polysaccharide | FRUITING BODY | SIGNALING PATHWAYS | POLYMER SCIENCE | CHEMISTRY, ORGANIC | ANTITUMOR-ACTIVITY | ANTIAGING ACTIVITIES | ZINC POLYSACCHARIDES | IN-VITRO | LIPOPOLYSACCHARIDE | MICE | PLEUROTUS-DJAMOR | CHEMISTRY, APPLIED | NF-KAPPA-B | Cellulase - chemistry | Tumor Necrosis Factor-alpha - metabolism | Lung Injury - pathology | Antioxidants - chemistry | Polygalacturonase - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Interleukin-1alpha - metabolism | Male | Protective Agents - chemistry | Protective Agents - therapeutic use | Polysaccharides - toxicity | Polysaccharides - chemistry | Lung Injury - drug therapy | Interleukin-6 - metabolism | Polysaccharides - therapeutic use | Lung - pathology | Glucuronidase - chemistry | Anti-Inflammatory Agents, Non-Steroidal - toxicity | Multienzyme Complexes - chemistry | Antioxidants - toxicity | Hydrolysis | Antioxidants - therapeutic use | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Mice | Mycelium - chemistry | Protective Agents - toxicity | Agaricales - chemistry | Antioxidants | Acute respiratory distress syndrome | Prevention | Enzymes | Polysaccharides | C-reactive protein | Interleukins | Anti-inflammatory drugs | Analysis | Superoxide | Mitogens | Index Medicus
Journal Article