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Nature cell biology, ISSN 1476-4679, 2013, Volume 15, Issue 7, pp. 807 - 817
Journal Article
BMC cancer, ISSN 1471-2407, 2006, Volume 6, Issue 1, pp. 225 - 225
Background: HER2/neu overexpression is linked to promotion of angiogenesis in breast cancer. We therefore tested the activity of the combination of Trastuzumab... 
PROTEIN | ANGIOGENESIS | ONCOLOGY | NEU ONCOGENE | EPIDERMAL-GROWTH-FACTOR | IN-VIVO | PHASE-II | MONOCLONAL-ANTIBODY | ANTITUMOR-ACTIVITY | FACTOR RECEPTOR | PLUS | Lung Neoplasms - drug therapy | Cyclophosphamide - administration & dosage | Humans | Middle Aged | Neoplasm Proteins - immunology | Bone Neoplasms - secondary | Antibodies, Monoclonal - therapeutic use | Neoplasm Proteins - antagonists & inhibitors | Cyclophosphamide - adverse effects | Bone Neoplasms - blood supply | Leukopenia - chemically induced | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Liver Neoplasms - secondary | Combined Modality Therapy | Lung Neoplasms - therapy | Lymphatic Metastasis | Breast Neoplasms - blood supply | Brain Neoplasms - drug therapy | Breast Neoplasms - drug therapy | Remission Induction | Methotrexate - adverse effects | Breast Neoplasms - genetics | Brain Neoplasms - therapy | Immunization, Passive | Methotrexate - administration & dosage | Trastuzumab | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Bone Neoplasms - therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Brain Neoplasms - blood supply | Liver Neoplasms - therapy | Ventricular Dysfunction, Left - chemically induced | Breast Neoplasms - therapy | Antibodies, Monoclonal, Humanized | Brain Neoplasms - secondary | Lung Neoplasms - secondary | Angiogenesis Inhibitors - therapeutic use | Adult | Female | Bone Neoplasms - drug therapy | Neutropenia - chemically induced | Lung Neoplasms - blood supply | Drug Administration Schedule | Liver Neoplasms - drug therapy | Treatment Outcome | Gene Amplification | Liver Neoplasms - blood supply | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Genes, erbB-2 | Aged
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 3, p. e91811
Background: We aimed to evaluate the clinical significance of microvessel density (MVD), lymphatic vessel density (LVD), and cancer-associated fibroblasts... 
HETEROGENEITY | SURVIVAL | MULTIDISCIPLINARY SCIENCES | BREAST CARCINOMAS | PTEN | MICROVESSEL DENSITY | STROMA | MUTATIONS | LYMPHATIC VESSEL DENSITY | TUMOR-GROWTH | EXPRESSION | Prognosis | Lung Neoplasms - mortality | Colorectal Neoplasms - genetics | Humans | Middle Aged | Neovascularization, Pathologic | Microvessels - pathology | Male | Ovarian Neoplasms - mortality | Liver Neoplasms - mortality | Actins - genetics | Ovarian Neoplasms - genetics | Lymphatic Vessels - blood supply | Ovarian Neoplasms - secondary | Lung Neoplasms - secondary | Aged, 80 and over | Peritoneal Neoplasms - blood supply | Adult | Female | Ovarian Neoplasms - blood supply | Liver Neoplasms - secondary | Lung Neoplasms - blood supply | Peritoneal Neoplasms - secondary | Colorectal Neoplasms - mortality | Lung Neoplasms - genetics | PTEN Phosphohydrolase - genetics | Colorectal Neoplasms - blood supply | Liver Neoplasms - genetics | Lymphatic Metastasis | Fibroblasts - pathology | Peritoneal Neoplasms - mortality | Liver Neoplasms - blood supply | Peritoneal Neoplasms - genetics | Lymphatic Vessels - pathology | Survival Analysis | Desmin - genetics | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - pathology | Immunohistochemistry | Cancer patients | Care and treatment | Metastasis | Muscle proteins | Colorectal cancer | Liver | Colorectal carcinoma | Regional analysis | Muscles | Smooth muscle | Patients | Desmin | Lymph nodes | Metastases | Studies | Pathology | Heterogeneity | Lungs | Actin | Rodents | Fibroblasts | Microenvironments | Microvasculature | Mutation | PTEN protein | Cancer | Peritoneum
Journal Article
Oncotarget, ISSN 1949-2553, 04/2016, Volume 7, Issue 15, pp. 20109 - 20123
Numerous antiangiogenic agents are approved for the treatment of oncological diseases. However, almost all patients develop evasive resistance mechanisms... 
Angiogenesis | Antiangiogenic therapies | Robo4 | Vascular endothelial growth factor (VEGF) | Placental growth factor (PlGF) | Neoplasms - metabolism | Lung Neoplasms - drug therapy | Prognosis | Follow-Up Studies | Humans | Lung Neoplasms - metabolism | Middle Aged | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Male | Kidney Neoplasms - metabolism | Carcinoma, Hepatocellular - drug therapy | Aged, 80 and over | Angiogenesis Inhibitors - therapeutic use | Biomarkers, Tumor - metabolism | Adult | Carcinoma, Hepatocellular - blood supply | Female | Liver Neoplasms - pathology | Carcinoma, Renal Cell - drug therapy | Carcinoma, Renal Cell - blood supply | Lung Neoplasms - blood supply | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - blood supply | Carcinoma, Renal Cell - pathology | Carcinoma, Non-Small-Cell Lung - metabolism | Liver Neoplasms - drug therapy | Neoplasms - blood supply | Survival Rate | Disease Progression | Neoplasms - drug therapy | Carcinoma, Renal Cell - metabolism | Pilot Projects | Liver Neoplasms - blood supply | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neovascularization, Pathologic - drug therapy | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Kidney Neoplasms - pathology | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Kidney Neoplasms - drug therapy | Neoplasm Staging | Neoplasms - pathology | Kidney Neoplasms - blood supply | Carcinoma, Hepatocellular - metabolism
Journal Article
PloS one, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155242
.... The immunohistochemical expression of various angiogenic factors in tissues from primary melanomas and metastases as well as their concentration in blood samples were examined... 
BREAST-CANCER | FACTOR VEGF | BIOMARKERS | CELLS | ANGIOGENESIS | NAB-PACLITAXEL | MULTIDISCIPLINARY SCIENCES | HSP27 | RESISTANCE | PLUS BEVACIZUMAB | ENDOTHELIAL GROWTH-FACTOR | Lung Neoplasms - drug therapy | Bevacizumab - therapeutic use | Prognosis | Skin Neoplasms - drug therapy | Melanoma - blood supply | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Vascular Endothelial Growth Factor A - genetics | Neovascularization, Pathologic - pathology | HSP27 Heat-Shock Proteins - genetics | Lung Neoplasms - secondary | Melanoma - genetics | Angiogenesis Inhibitors - therapeutic use | Adult | Female | Skin Neoplasms - blood supply | Liver Neoplasms - secondary | Lung Neoplasms - blood supply | Lung Neoplasms - genetics | Skin Neoplasms - pathology | Liver Neoplasms - genetics | Signal Transduction | Liver Neoplasms - drug therapy | Vascular Endothelial Growth Factor A - blood | Lymphatic Metastasis | Fibroblast Growth Factor 2 - blood | HSP27 Heat-Shock Proteins - blood | Melanoma - secondary | Biomarkers, Tumor - blood | Fibroblast Growth Factor 2 - genetics | Liver Neoplasms - blood supply | Neovascularization, Pathologic - drug therapy | Melanoma - drug therapy | Skin Neoplasms - genetics | Neovascularization, Pathologic - genetics | Biomarkers, Tumor - genetics | Melanoma | Heat shock proteins | Physiological aspects | Development and progression | Genetic aspects | Research | Metastasis | Drug therapy | Fibroblast growth factor | Colorectal cancer | Tissues | Cancer therapies | Density | Blood | Bevacizumab | Metastases | Skin cancer | Angiogenesis | Surgery | Fibroblasts | Bioindicators | Vascular endothelial growth factor | Fibroblast growth factor 2 | Splicing | Breast cancer | Patients | Blood levels | Chemotherapy | Hospitals | Hsp27 protein | Medical prognosis | Biomarkers | Microvasculature | Clinical medicine | Tumors | Heat shock
Journal Article
International journal of radiation oncology, biology, physics, ISSN 0360-3016, 2012, Volume 82, Issue 5, pp. e725 - e731
... were observed, with decreasing tissue blood volume fractions. Introduction Positron emission tomography (PET) is a molecular imaging technique to quantitatively assess... 
Radiology | Hematology, Oncology and Palliative Medicine | Positron-emission tomography | Fluorodeoxyglucose F18 | Patlak analysis | Tissue distribution | Pharmacokinetics | CEREBRAL GLUCOSE-UTILIZATION | BLOOD-FLOW | HYPOXIA | CELL LUNG-CANCER | CHEMOTHERAPY RESPONSE EVALUATION | F-18-FDG PET | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | COLORECTAL-CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Neoplasms - metabolism | Fluorodeoxyglucose F18 - pharmacokinetics | Phosphorylation | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Breast Neoplasms - metabolism | Blood Volume | Adult | Female | Breast Neoplasms - diagnostic imaging | Colorectal Neoplasms - metabolism | Lung Neoplasms - blood supply | Radiopharmaceuticals - pharmacokinetics | Colorectal Neoplasms - blood supply | Carcinoma, Non-Small-Cell Lung - blood supply | Carcinoma, Non-Small-Cell Lung - metabolism | Neoplasms - blood supply | Colorectal Neoplasms - diagnostic imaging | Breast Neoplasms - blood supply | Positron-Emission Tomography - methods | Neoplasms - diagnostic imaging | Glucose - metabolism | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Glucose metabolism | PET imaging | Analysis | Physiological aspects | Glucose | Dextrose | Tumors | PATIENTS | REACTION KINETICS | NEOPLASMS | PHOSPHORYLATION | FLUORODEOXYGLUCOSE | RADIATION DOSES | SIMULATION | METABOLISM | GLUCOSE | POSITRON COMPUTED TOMOGRAPHY | UPTAKE | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | FLUORINE 18 | BLOOD
Journal Article
Critical reviews in oncology/hematology, ISSN 1040-8428, 2016, Volume 100, pp. 177 - 189
... are expressed, such as vascular endothelial cadherin and von Willebrand factor. The frequency of CD34+ cells which also express CD309 and CD133 in peripheral blood... 
Hematology, Oncology and Palliative Medicine | Angiogenesis | Tumour | Endothelial progenitor cell | Metastasis | Interaction | PREDICTIVE MARKERS | RECRUITMENT | TGF-BETA | NECROSIS-FACTOR-ALPHA | CANCER | MESENCHYMAL STEM-CELLS | BONE-MARROW MICROENVIRONMENT | ONCOLOGY | NITRIC-OXIDE | GROWTH-FACTOR | HEMATOLOGY | CLINICAL-SIGNIFICANCE | Prognosis | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Carcinoma, Non-Small-Cell Lung - diagnosis | Tumor Microenvironment - physiology | Neoplasm Recurrence, Local - etiology | Neovascularization, Pathologic - pathology | Breast Neoplasms - therapy | Neoplasm Recurrence, Local - pathology | Endothelial Progenitor Cells - physiology | Female | Ovarian Neoplasms - blood supply | Lung Neoplasms - blood supply | Carcinoma, Non-Small-Cell Lung - pathology | Neoplasm Metastasis - therapy | Signal Transduction | Carcinoma, Non-Small-Cell Lung - blood supply | Lung Neoplasms - therapy | Neoplasm Recurrence, Local - diagnosis | Breast Neoplasms - blood supply | Carcinoma, Non-Small-Cell Lung - therapy | Breast Neoplasms - pathology | Neoplasm Metastasis - pathology | Neoplasm Metastasis - diagnosis | Breast Neoplasms - diagnosis | Lung Neoplasms - diagnosis | Medical colleges | Development and progression | Neovascularization | Lung cancer, Non-small cell | Health aspects | Ovarian cancer | Endothelium | Cancer
Journal Article
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 2014, Volume 74, Issue 11, pp. 2962 - 2973
Journal Article
Cancer cell, ISSN 1535-6108, 2016, Volume 29, Issue 4, pp. 508 - 522
.... In contrast, SHH-medulloblastoma, a less curable disease subtype, contains an intact blood brain barrier, rendering this tumor impermeable and resistant to chemotherapy... 
LUNG-CANCER | ANGIOGENESIS | ONCOLOGY | PATHWAY | IN-VIVO | VINCRISTINE | TUMOR | CNS | CENTRAL-NERVOUS-SYSTEM | SUBGROUPS | CHEMOTHERAPY | CELL BIOLOGY | Humans | Neoplasm Proteins - physiology | Cerebellar Neoplasms - blood supply | Culture Media, Conditioned - pharmacology | Genetic Vectors - therapeutic use | Medulloblastoma - secretion | Recombinant Fusion Proteins - metabolism | Endothelium, Vascular - ultrastructure | Cerebellar Neoplasms - secretion | Wnt Proteins - genetics | Membrane Proteins - physiology | Pericytes - pathology | Glucose Transporter Type 1 - physiology | Antineoplastic Agents - pharmacokinetics | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Vincristine - pharmacokinetics | Disease Models, Animal | Carrier Proteins - physiology | Cerebellar Neoplasms - drug therapy | Transduction, Genetic | Genetic Association Studies | Genotype | Mice, Transgenic | Cerebellar Neoplasms - genetics | Tight Junctions - ultrastructure | Animals | Wnt Signaling Pathway - drug effects | Endothelium, Vascular - metabolism | Paracrine Communication - drug effects | Vincristine - therapeutic use | Medulloblastoma - blood supply | Mice | Wnt Proteins - physiology | Medulloblastoma - drug therapy | Drug Resistance, Neoplasm - physiology | Medulloblastoma - classification | Blood-Brain Barrier | Chemotherapy | Medulloblastoma | Brain tumors | Genetic aspects | Permeability | Cells | Cancer | Neurophysiology | Endothelium
Journal Article