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Journal of Neuroimmunology, ISSN 0165-5728, 2015, Volume 284, pp. 18 - 29
...) and D5R, and how this modulation affects CD4+ T-cell activation and differentiation. Our pharmacologic and genetic evidence shows that D3R-stimulation reduced cAMP levels and ERK2-phosphorylation, consequently increasing CD4... 
Neurology | Allergy and Immunology | Knockout mice | Th1 differentiation | Neuroimmunology | TCR signalling | T-cell activation | Dopamine receptors | IMMUNITY | DENDRITIC CELLS | NEURODEGENERATION | PROLIFERATION | IMMUNOLOGY | NEUROSCIENCES | IN-VITRO | CD4+AND CD8+T CELLS | SECRETION | TH1 | CYTOTOXICITY | LYMPHOCYTES | T-Lymphocytes - physiology | Receptors, Dopamine D3 - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Dose-Response Relationship, Drug | Receptors, Dopamine D3 - genetics | Cell Differentiation - genetics | Lymphocyte Activation - genetics | Phosphorylation - genetics | Dopamine Agents - pharmacology | T-Lymphocytes - drug effects | Phosphorylation - drug effects | Cell Differentiation - physiology | Cyclic AMP - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Signal Transduction - genetics | Enzyme Activation - drug effects | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Signal Transduction - drug effects | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Ionomycin - pharmacology | Receptors, Dopamine D5 - metabolism | Mice | Receptors, Dopamine D5 - genetics | Enzyme Activation - genetics | CD4 Antigens - metabolism
Journal Article
Immunological Reviews, ISSN 0105-2896, 07/2013, Volume 254, Issue 1, pp. 78 - 101
Summary Systemic chronic immune activation is considered today as the driving force of CD4... 
SIV | pathogenesis | HIV | inflammation | immune activation | natural hosts | Immune activation | Inflammation | Pathogenesis | Natural hosts | LONG-TERM NONPROGRESSORS | RECEIVING ANTIRETROVIRAL THERAPY | AFRICAN-GREEN MONKEYS | CD4(+) T-CELLS | NONPATHOGENIC SIV INFECTION | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | PLASMACYTOID DENDRITIC CELLS | SIMIAN IMMUNODEFICIENCY VIRUS | LYMPHOID-TISSUE | INFECTED SOOTY MANGABEYS | HIV-1 - metabolism | Lymphoid Tissue - virology | HIV Infections - virology | Humans | Viral Proteins - immunology | Lymphocyte Depletion | Lymphoid Tissue - immunology | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV-1 - immunology | Lymphocyte Activation - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Animals | Simian Acquired Immunodeficiency Syndrome - immunology | Virus Replication | CD4-Positive T-Lymphocytes - virology | HIV (Viruses) | T cells | HIV infection | Lymphoid Tissue/immunology | HIV-1/immunology | HIV Infections/immunology | HIV-1/metabolism | Lymphoid Tissue/virology | Virology | Life Sciences | Simian Acquired Immunodeficiency Syndrome/virology | Microbiology and Parasitology | Immunology | CD4-Positive T-Lymphocytes/immunology | Lymphocyte Activation/immunology | HIV Infections/virology | CD4-Positive T-Lymphocytes/virology | Simian Acquired Immunodeficiency Syndrome/immunology | Viral Proteins/immunology
Journal Article