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Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 498 - 511.e6
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 5, pp. 1144 - 1152.e11
Background Signals emanating from the antigen T-cell receptor (TCR) are required for T-cell development and function. The T lymphocyte–specific protein... 
Allergy and Immunology | LCK, SRC tyrosine kinase | recurrent infections | CD4 | T-cell receptor signaling | autoinflammation | immunodeficiency | genetic defect | lymphopenia | ACTIVATION | COMPLEX | SRC tyrosine kinase | PROTEIN-TYROSINE KINASES | P56(LCK) | IMMUNOLOGY | MICE LACKING | SIGNAL-TRANSDUCTION | ALLERGY | LCK | MUTATION | DOCK8 DEFICIENCY | FYN | ANTIGEN RECEPTOR | Genetic Predisposition to Disease | T-Lymphocytopenia, Idiopathic CD4-Positive - diagnosis | Receptors, Antigen, T-Cell - metabolism | Genes, Recessive - genetics | Humans | Cells, Cultured | Child, Preschool | T-Lymphocytopenia, Idiopathic CD4-Positive - genetics | Mutation, Missense - genetics | Polymorphism, Genetic | CD4-Positive T-Lymphocytes - immunology | DNA Mutational Analysis | Pedigree | Immunologic Deficiency Syndromes - genetics | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - chemistry | Female | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - genetics | Calcium Signaling - genetics | France | Immunologic Deficiency Syndromes - diagnosis | Tyrosine | Antigens | T cells | Genes | Immunodeficiency | T cell receptors | Infections | Kinases | Viral infections | Immune system | Autoimmunity | Calcium mobilization | Phosphorylation | CD8 antigen | Recurrent infection | Inflammation | Lymphocytes T | Risk factors | CD4 antigen | Calcium signalling | T-cell receptor | Missense mutation | Lymphopenia | Lck protein | Respiratory tract diseases | Differentiation | Protein-tyrosine kinase | Age | uniparental disomy | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Journal Article
Journal Article
Science Signaling, ISSN 1945-0877, 12/2015, Volume 8, Issue 405, pp. rs13 - rs13
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 20, pp. 7824 - 7840
The HIV type 1 pathogenicity factor Nef enhances viral replication by modulating multiple host cell pathways, including tuning the activation state of infected... 
PDE-DELTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | T-CELL-ACTIVATION | VIRUS TYPE-1 NEF | SUBCELLULAR-LOCALIZATION | DOWN-REGULATION | SURFACE | INFECTION | IMMUNOLOGICAL SYNAPSE | MAL PROTEIN | C-SRC | Humans | T-Lymphocytes - virology | Proto-Oncogene Proteins c-fyn - genetics | trans-Golgi Network - metabolism | trans-Golgi Network - virology | T-Lymphocytes - metabolism | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - chemistry | nef Gene Products, Human Immunodeficiency Virus - metabolism | Cell Membrane - metabolism | Protein Interaction Domains and Motifs | ADP-Ribosylation Factors - metabolism | ADP-Ribosylation Factors - genetics | Binding Sites | Amino Acid Sequence | HIV-1 - metabolism | Signal Transduction | Jurkat Cells | Gene Expression Regulation | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - metabolism | HIV-1 - genetics | Protein Transport | Host-Pathogen Interactions | Proto-Oncogene Proteins c-fyn - metabolism | nef Gene Products, Human Immunodeficiency Virus - genetics | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Cell Membrane - virology | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - genetics | Primary Cell Culture | Adaptor Proteins, Signal Transducing - metabolism | lipid binding protein | Molecular Bases of Disease | anterograde transport | HIV | Src | lipoprotein binding chaperone | host–pathogen interaction | Src family kinase | membrane transport | Nef
Journal Article