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Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2004, Volume 173, Issue 7, pp. 4479 - 4491
TLRs are pattern recognition receptors that initiate innate immune responses. TLR9 detects microbial DNA with hypomethylated CpG motifs and in humans is... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | SIGNALING PATHWAYS | TARGETED DISRUPTION | DENDRITIC CELLS | INTERFERON-GAMMA | SYNERGISTIC ACTIVATION | TOLL-LIKE RECEPTORS | CD40-MEDIATED ACTIVATION | IMMUNOLOGY | NF-KAPPA-B | BACTERIAL-DNA | Receptors, Immunologic - physiology | Humans | Membrane Glycoproteins - biosynthesis | Transcriptional Activation - drug effects | Immunity, Innate - genetics | Interleukin-1 Receptor-Associated Kinases | Toll-Like Receptor 9 | Receptors, Antigen, B-Cell - metabolism | Transcriptional Activation - immunology | Chloroquine - pharmacology | Toll-Like Receptors | Lymphocyte Activation - genetics | Membrane Glycoproteins - physiology | Immunoglobulin G - biosynthesis | Membrane Proteins - physiology | Receptors, Antigen, B-Cell - physiology | Receptors, Cell Surface - physiology | Immunoglobulin Class Switching - drug effects | Adjuvants, Immunologic - physiology | NF-kappa B p50 Subunit | Signal Transduction - genetics | Immunoglobulin Constant Regions - metabolism | Response Elements - immunology | Antigens, Differentiation - physiology | Immunoglobulin mu-Chains - genetics | Adaptor Proteins, Signal Transducing | B-Cell Activating Factor | B-Lymphocytes - immunology | Immunoglobulin G - genetics | Signal Transduction - drug effects | Up-Regulation - immunology | Tumor Necrosis Factor-alpha - physiology | Gene Rearrangement, B-Lymphocyte - drug effects | Immunoglobulin G - metabolism | CD40 Ligand - physiology | DNA, Bacterial - pharmacology | Immunoglobulin gamma-Chains - genetics | Interleukin-10 - physiology | Cytidine Deaminase - biosynthesis | Signal Transduction - immunology | DNA, Bacterial - physiology | Immunoglobulin Constant Regions - genetics | Immunoglobulin gamma-Chains - metabolism | Receptors, Cell Surface - biosynthesis | Cell Line | Proteins - physiology | B-Lymphocytes - enzymology | Immunoglobulin mu-Chains - metabolism | Myeloid Differentiation Factor 88 | B-Lymphocytes - drug effects | TNF Receptor-Associated Factor 6 | Protein Kinases - physiology | NF-kappa B - physiology | Promoter Regions, Genetic - immunology | Immunoglobulin Class Switching - genetics | Interleukin-10 - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2006, Volume 7, Issue 7, pp. 773 - 782
B cells producing high-affinity antibodies are destined to differentiate into memory B cells and plasma cells, but the mechanisms leading to those... 
CENTER B-CELLS | GERMINAL-CENTER FORMATION | SOMATIC HYPERMUTATION | AFFINITY MATURATION | BLIMP-1 EXPRESSION | GENE-EXPRESSION | PRIMARY IMMUNIZATION | REGULATORY FACTOR FAMILY | HODGKIN LYMPHOMA | TERMINAL DIFFERENTIATION | IMMUNOLOGY | Germinal Center - immunology | Male | Interferon Regulatory Factors - deficiency | X-Box Binding Protein 1 | Repressor Proteins - physiology | Flow Cytometry | Immunoglobulin G - biosynthesis | Immunoglobulin Class Switching - physiology | Interferon Regulatory Factors - physiology | Female | Transcription, Genetic | Germinal Center - cytology | Cell Differentiation - physiology | B-Lymphocytes - cytology | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Mice, Inbred C57BL | Gene Expression Regulation - physiology | Interferon Regulatory Factors - genetics | Mice, Transgenic | Antibody Formation - physiology | Regulatory Factor X Transcription Factors | Mice, Knockout | Immunologic Memory - physiology | Models, Immunological | Animals | B-Lymphocytes - immunology | Immunoglobulin G - genetics | Antigens - immunology | Mice | Nuclear Proteins - physiology | Immunoglobulin Class Switching - genetics | Lymphocyte Activation - physiology | Plasma Cells - cytology | Crosses, Genetic | Plasma Cells - immunology | Positive Regulatory Domain I-Binding Factor 1 | Proto-Oncogene Proteins c-bcl-6 | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 07/2010, Volume 116, Issue 4, pp. 617 - 624
Human blood neutrophils rolling on E-or P-selectin reduced their rolling velocity when intercellular adhesion molecule (ICAM)-1 was available. Similar to mouse... 
SIGNAL-TRANSDUCTION | CYTOPLASMIC DOMAIN | INFLAMMATION IN-VIVO | ARREST | INTERCELLULAR-ADHESION MOLECULE-1 | INTEGRIN ACTIVATION | ENDOTHELIAL-CELLS | OUTSIDE-IN | LEUKOCYTE ADHESION | HEMATOLOGY | GLYCOPROTEIN LIGAND-1 | Membrane Glycoproteins - metabolism | P-Selectin - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Substrate Specificity | Type C Phospholipases - metabolism | Lymphocyte Function-Associated Antigen-1 - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Protein-Tyrosine Kinases - physiology | Membrane Glycoproteins - physiology | U937 Cells | src-Family Kinases - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | src-Family Kinases - physiology | Neutrophils - metabolism | Syk Kinase | Lymphocyte Function-Associated Antigen-1 - chemistry | Lymphocyte Function-Associated Antigen-1 - physiology | p38 Mitogen-Activated Protein Kinases - physiology | Neutrophils - physiology | E-Selectin - metabolism | Leukocyte Rolling - immunology | P-Selectin - physiology | Leukocyte Rolling - physiology | Protein Conformation | E-Selectin - physiology | Intracellular Signaling Peptides and Proteins - physiology | Type C Phospholipases - physiology | Protein Binding - physiology | Index Medicus | Abridged Index Medicus | Phagocytes, Granulocytes, and Myelopoiesis
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2005, Volume 174, Issue 12, pp. 7506 - 7515
Journal Article