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Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 11/2010, Volume 202, Issue 9, pp. 1424 - 1434
Journal Article
Leukemia, ISSN 0887-6924, 12/2014, Volume 28, Issue 12, pp. 2376 - 2387
Journal Article
Journal Article
Leukemia, ISSN 0887-6924, 12/2014, Volume 28, Issue 12, pp. 2367 - 2375
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 1/2015, Volume 75, Issue 1, pp. 111 - 121
Ibrutinib is an oral Bruton’s tyrosine kinase inhibitor, recently approved for the treatment of mantle cell lymphoma (MCL) and chronic lymphocytic leukemia... 
Nonlinear mixed effects model | Medicine & Public Health | ADME | Covariate analysis | Oncology | Cancer Research | Phase I–II | Pharmacology/Toxicology | Phase I-II | ONCOLOGY | THERAPEUTIC TARGET | PCI-32765 | BTK | PHARMACOLOGY & PHARMACY | Pyrazoles - therapeutic use | Pyrimidines - blood | Humans | Middle Aged | Half-Life | Biological Availability | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Intestinal Absorption | Dose-Response Relationship, Drug | Lymphoma, Mantle-Cell - blood | Pyrazoles - blood | Aged, 80 and over | Adult | Female | Leukemia, Lymphocytic, Chronic, B-Cell - blood | Antineoplastic Agents - pharmacokinetics | Pyrazoles - pharmacokinetics | Lymphoma, Mantle-Cell - metabolism | Protein Kinase Inhibitors - pharmacokinetics | Pyrimidines - administration & dosage | Food-Drug Interactions | Lymphoma, Mantle-Cell - drug therapy | Protein Kinase Inhibitors - blood | Cross-Over Studies | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Models, Biological | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Antineoplastic Agents - blood | Pyrimidines - pharmacokinetics | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Cohort Studies | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Care and treatment | Analysis | Leukemia | Phenols | Lymphomas | Models | Antacids
Journal Article