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The Journal of clinical investigation, ISSN 0021-9738, 09/2016, Volume 126, Issue 9, pp. 3351 - 3362
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 02/2014, Volume 111, Issue 6, pp. 2349 - 2354
Journal Article
Blood, ISSN 1528-0020, 12/2016, Volume 128, Issue 26, pp. 3083 - 3100
Journal Article
Journal Article
Nature medicine, ISSN 1546-170X, 12/2009, Volume 16, Issue 1, pp. 123 - 128
Journal Article
Nature (London), ISSN 1476-4687, 01/2010, Volume 463, Issue 7277, pp. 88 - 92
Journal Article
Nature (London), ISSN 0028-0836, 05/2015, Volume 521, Issue 7552, pp. 357 - 361
B cells are selected for an intermediate level of B-cell antigen receptor (BCR) signalling strength... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein-Tyrosine Kinases - metabolism | Receptors, Antigen, B-Cell - deficiency | Humans | Precursor Cells, B-Lymphoid - metabolism | Inositol Polyphosphate 5-Phosphatases | Intracellular Signaling Peptides and Proteins - metabolism | Precursor Cells, B-Lymphoid - drug effects | Receptors, Antigen, B-Cell - metabolism | Antigens, CD - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Precursor Cells, B-Lymphoid - pathology | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Gene Deletion | Female | B-Lymphocytes - pathology | Cell Death - drug effects | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Syk Kinase | B-Lymphocytes - metabolism | Disease Models, Animal | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Enzyme Activation - drug effects | Mice, SCID | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | B-Lymphocytes - drug effects | Fusion Proteins, bcr-abl - genetics | Tyrosine - metabolism | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Signal Transduction - drug effects | Cell Transformation, Neoplastic | Intracellular Signaling Peptides and Proteins - agonists | Cell Line, Tumor | Mice, Inbred NOD | Receptors, Antigen, B-Cell - genetics | Mice | Amino Acid Motifs - genetics | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases | Phosphoric Monoester Hydrolases - metabolism | Receptors, Immunologic - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - deficiency | Receptors, Immunologic - metabolism | Drug Resistance, Neoplasm - drug effects | Physiological aspects | Acute lymphocytic leukemia | B cells | Signal transduction | Rodents | Leukemia | Mutation | Drug resistance | Kinases | Cells | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 06/2018, Volume 560, Issue 7718, pp. 387 - 391
B cell receptor (BCR) signalling has emerged as a therapeutic target in B cell lymphomas, but inhibiting this pathway in diffuse large B cell lymphoma (DLBCL... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Pyrazoles - therapeutic use | TOR Serine-Threonine Kinases - metabolism | Humans | Toll-Like Receptor 9 - genetics | NF-kappa B - metabolism | Lymphoma, Large B-Cell, Diffuse - metabolism | Receptors, Antigen, B-Cell - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Drug Design | Female | Tumor Cells, Cultured | Pyrazoles - pharmacology | Lymphoma, Large B-Cell, Diffuse - pathology | Carcinogenesis - genetics | Myeloid Differentiation Factor 88 - genetics | Receptors, Antigen, B-Cell - antagonists & inhibitors | Signal Transduction - genetics | Pyrimidines - pharmacology | CRISPR-Cas Systems - genetics | Xenograft Model Antitumor Assays | Multiprotein Complexes - chemistry | Animals | Signal Transduction - drug effects | Biopsy | Pyrimidines - therapeutic use | Proteomics | Receptors, Antigen, B-Cell - genetics | Mice | Mutation | Toll-Like Receptor 9 - metabolism | Lymphoma, Large B-Cell, Diffuse - genetics | Myeloid Differentiation Factor 88 - metabolism | Lymphomas | Genetic aspects | B cells | Health aspects | TOR protein | Protein kinase C | Toxicity | Genomes | B-cell receptor | Kinases | Gene sequencing | Proteins | Signal transduction | Dependence | Toll-like receptors | CRISPR | NF-κB protein | Therapeutic applications | Autoantigens | Gene expression | Lymphoma | Bruton's tyrosine kinase | TLR9 protein | Signaling | Inhibitors | Lymphocytes B | Bcl-10 protein | MyD88 protein | Syk protein | Scientific imaging | Mass spectrometry | Cancer | Tumors | B-cell lymphoma | Index Medicus | Life Sciences | Immunology
Journal Article