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Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 11/2009, Volume 106, Issue 47, pp. 19946 - 19951
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 8/2014, Volume 111, Issue 31, pp. 11365 - 11370
Journal Article
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2015, Volume 54, pp. 11 - 17
Abstract Purpose To assess the safety and efficacy of fostamatinib in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL... 
Hematology, Oncology and Palliative Medicine | Clinical trial | DLBCL | Syk inhibitor | Phase II | B-cell receptor | Life Sciences & Biomedicine | Oncology | Science & Technology | Recurrence | Protein-Tyrosine Kinases - metabolism | United States | Humans | Middle Aged | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Intracellular Signaling Peptides and Proteins - metabolism | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Pyridines - adverse effects | Time Factors | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Oxazines - administration & dosage | Syk Kinase | Pyridines - therapeutic use | Lymphoma, Large B-Cell, Diffuse - drug therapy | Pyridines - administration & dosage | Drug Administration Schedule | Lymphoma, Large B-Cell, Diffuse - pathology | Administration, Oral | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Lymphoma, Large B-Cell, Diffuse - enzymology | Treatment Outcome | Disease Progression | Oxazines - adverse effects | Protein Kinase Inhibitors - administration & dosage | Oxazines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Aged | Protein-Tyrosine Kinases - antagonists & inhibitors | Clinical trials | Care and treatment | Relapse | Lymphomas | Diseases | Medical research | Analysis | Medicine, Experimental | Index Medicus
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 10/2012, Volume 492, Issue 7427, pp. 108 - 112
...). Additionally, somatic heterozygous mutations of Y641 and A677 residues within the catalytic SET domain of EZH2 occur in diffuse large B-cell lymphoma (DLBCL... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Polycomb Repressive Complex 2 - antagonists & inhibitors | Neoplasm Transplantation | Gene Silencing - drug effects | Lymphoma, Follicular - drug therapy | Polycomb Repressive Complex 2 - genetics | Histones - chemistry | Humans | Transcriptional Activation - drug effects | Transplantation, Heterologous | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Lymphoma, Follicular - genetics | Indoles - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Repressor Proteins - metabolism | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - chemistry | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - pathology | Lymphoma, Follicular - pathology | Lymphoma, Large B-Cell, Diffuse - enzymology | Mutation - genetics | Enhancer of Zeste Homolog 2 Protein | Animals | Histone-Lysine N-Methyltransferase - metabolism | Methylation - drug effects | Cell Line, Tumor | Indoles - therapeutic use | Lymphoma, Follicular - enzymology | Cell Proliferation - drug effects | Mice | Pyridones - therapeutic use | Histones - metabolism | Polycomb Repressive Complex 2 - metabolism | Lymphoma, Large B-Cell, Diffuse - genetics | Pyridones - pharmacology | Gene mutations | Methyltransferases | Physiological aspects | Lymphomas | Genetic aspects | Research | Health aspects | Risk factors | Care and treatment | Proteins | Cell growth | Cytotoxicity | Mutation | Gene expression | Laboratory animals | Tumors | Apoptosis | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, pp. e0171221 - e0171221
Journal Article
Journal Article
Leukemia, ISSN 1476-5551, 10/2015, Volume 30, Issue 3, pp. 617 - 626
Angiogenesis associates with poor outcome in diffuse large B-cell lymphoma (DLBCL), but the contribution of the lymphoma cells to this process remains unclear... 
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Humans | Gene Expression Regulation, Neoplastic | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Proto-Oncogene Proteins c-akt - genetics | Neovascularization, Pathologic - pathology | Neovascularization, Pathologic - enzymology | Neovascularization, Pathologic - prevention & control | Benzamides - pharmacology | B-Lymphocytes - pathology | Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cyclic AMP - metabolism | Cyclopropanes - pharmacology | Disease Models, Animal | Tumor Microenvironment - drug effects | B-Lymphocytes - enzymology | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - pathology | Signal Transduction | Lymphoma, Large B-Cell, Diffuse - enzymology | Mice, Transgenic | Cyclic Nucleotide Phosphodiesterases, Type 4 - genetics | Phosphodiesterase 4 Inhibitors - pharmacology | Proto-Oncogene Proteins c-myc - metabolism | Phosphatidylinositol 3-Kinases - genetics | B-Lymphocytes - drug effects | Animals | Aminopyridines - pharmacology | Neovascularization, Pathologic - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Lymphoma, Large B-Cell, Diffuse - genetics | Development and progression | Care and treatment | Research | Neovascularization | Non-Hodgkin's lymphomas | Vascular endothelial growth factor | Index Medicus
Journal Article