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Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7337, pp. 189 - 195
B-cell non-Hodgkin's lymphoma comprises biologically and clinically distinct diseases the pathogenesis of which is associated with genetic lesions affecting... 
CBP | RUBINSTEIN-TAYBI SYNDROME | HISTONE ACETYLTRANSFERASES | ACETYLATION | P300 | MULTIDISCIPLINARY SCIENCES | CREB-BINDING-PROTEIN | CYCLE ARREST | ACUTE MYELOID-LEUKEMIA | TRANSCRIPTIONAL COACTIVATOR | P53 | Histone Acetyltransferases - deficiency | Recurrence | Acetyltransferases - metabolism | Histone Acetyltransferases - chemistry | Humans | E1A-Associated p300 Protein - genetics | Gene Expression Regulation, Neoplastic | Histone Acetyltransferases - genetics | CREB-Binding Protein - chemistry | E1A-Associated p300 Protein - metabolism | Lymphoma, B-Cell - genetics | Acetyltransferases - genetics | Mutation, Missense - genetics | CREB-Binding Protein - genetics | DNA-Binding Proteins - metabolism | CREB-Binding Protein - metabolism | Lymphoma, Follicular - genetics | Acetyltransferases - deficiency | Base Sequence | Histone Acetyltransferases - metabolism | Lymphoma, B-Cell - enzymology | HEK293 Cells | Acetylation | CREB-Binding Protein - deficiency | Lymphoma, Large B-Cell, Diffuse - pathology | Lymphoma, Follicular - pathology | Cells, Cultured | E1A-Associated p300 Protein - chemistry | Lymphoma, Large B-Cell, Diffuse - enzymology | Tumor Suppressor Protein p53 - metabolism | Protein Structure, Tertiary - genetics | Mutation - genetics | Acetyl Coenzyme A - metabolism | Acetyltransferases - chemistry | Animals | Lymphoma, B-Cell - pathology | Polymorphism, Single Nucleotide - genetics | Protein Binding | Lymphoma, Follicular - enzymology | Mice | E1A-Associated p300 Protein - deficiency | Lymphoma, Large B-Cell, Diffuse - genetics | Proto-Oncogene Proteins c-bcl-6 | Sequence Deletion - genetics | Lymphomas | Genetic aspects | B cells | Gene mutations | Health aspects | Abnormalities | Proteins | Congenital diseases | Pathogenesis | Genes | Cell cycle | Genomes | Genetic engineering | Mutation | Binding sites | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7379, pp. 90 - 94
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 31, pp. 11365 - 11370
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2013, Volume 23, Issue 6, pp. 826 - 838
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 47, pp. 19946 - 19951
A key element for the development of suitable anti-cancer drugs is the identification of cancer-specific enzymatic activities that can be therapeutically... 
T lymphocytes | Cytokines | B lymphocytes | B cell lymphoma | Cell lines | Antibodies | Signatures | Gene expression | Viability | Cells | DLBCL | NF-kB | CARMA1 | MULTIDISCIPLINARY SCIENCES | T-CELL | CHEMOTHERAPY | C-FLIP | MALIGNANCIES | INHIBITORS | DIFFERENTIATION | NF-KAPPA-B | EXPRESSION | LYMPHOCYTES | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Regulation, Neoplastic | NF-kappa B - metabolism | Neoplasm Proteins - antagonists & inhibitors | Gene Expression Profiling | Neoplasm Proteins - metabolism | CARD Signaling Adaptor Proteins - genetics | Antineoplastic Agents - metabolism | CARD Signaling Adaptor Proteins - metabolism | Caspases - metabolism | Neoplasm Proteins - genetics | Lung Neoplasms - enzymology | Caspases - genetics | Lymphoma, Large B-Cell, Diffuse - enzymology | Guanylate Cyclase - metabolism | Caspase Inhibitors | Animals | NF-kappa B - genetics | B-Cell CLL-Lymphoma 10 Protein | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Guanylate Cyclase - genetics | Signal Transduction - physiology | Mice | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein | Adaptor Proteins, Signal Transducing - metabolism | Physiological aspects | Lymphomas | Genetic aspects | B cells | Properties | Proteases | Proteins | Cell growth | Pharmacology | Enzyme kinetics | Index Medicus | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 12/2012, Volume 491, Issue 7427, pp. 108 - 112
In eukaryotes, post-translational modification of histones is critical for regulation of chromatin structure and gene expression. EZH2 is the catalytic subunit... 
LYSINE 27 | METHYLATION | MULTIDISCIPLINARY SCIENCES | B-CELL LYMPHOMAS | GENES | HISTONE METHYLTRANSFERASE EZH2 | H3K27 | HYPERTRIMETHYLATION | SOMATIC MUTATIONS | HUMAN CANCER | Polycomb Repressive Complex 2 - antagonists & inhibitors | Neoplasm Transplantation | Gene Silencing - drug effects | Lymphoma, Follicular - drug therapy | Polycomb Repressive Complex 2 - genetics | Histones - chemistry | Humans | Transcriptional Activation - drug effects | Transplantation, Heterologous | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Lymphoma, Follicular - genetics | Indoles - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Repressor Proteins - metabolism | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - chemistry | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - pathology | Lymphoma, Follicular - pathology | Lymphoma, Large B-Cell, Diffuse - enzymology | Mutation - genetics | Enhancer of Zeste Homolog 2 Protein | Animals | Histone-Lysine N-Methyltransferase - metabolism | Methylation - drug effects | Cell Line, Tumor | Indoles - therapeutic use | Lymphoma, Follicular - enzymology | Cell Proliferation - drug effects | Mice | Pyridones - therapeutic use | Histones - metabolism | Polycomb Repressive Complex 2 - metabolism | Lymphoma, Large B-Cell, Diffuse - genetics | Pyridones - pharmacology | Gene mutations | Methyltransferases | Physiological aspects | Lymphomas | Genetic aspects | Research | Health aspects | Risk factors | Care and treatment | Proteins | Cell growth | Cytotoxicity | Mutation | Gene expression | Laboratory animals | Tumors | Apoptosis | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 12/2006, Volume 108, Issue 13, pp. 4178 - 4186
Journal Article
Nature, ISSN 0028-0836, 08/2011, Volume 476, Issue 7360, pp. 298 - 303
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Journal Article
Journal Article