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Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 6, pp. 770 - 778
Summary Background Pancreatic cancer statistics are dismal, with a 5-year survival of less than 10%, and more than 50% of patients presenting with metastatic... 
Hematology, Oncology and Palliative Medicine | ONCOLOGY | MITOCHONDRIAL METABOLISM | Leucovorin - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Sulfides - administration & dosage | Pancreatic Neoplasms - drug therapy | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Hyperglycemia - chemically induced | Leucovorin - adverse effects | Fluorouracil - adverse effects | Hypokalemia - chemically induced | Camptothecin - administration & dosage | Female | Neutropenia - chemically induced | Camptothecin - analogs & derivatives | Camptothecin - adverse effects | Hematologic Diseases - chemically induced | Sensation Disorders - chemically induced | Abdominal Pain - chemically induced | Pancreatic Neoplasms - pathology | Anemia - chemically induced | Thrombocytopenia - chemically induced | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Hypoalbuminemia - chemically induced | Maximum Tolerated Dose | Sepsis - chemically induced | Sulfides - adverse effects | Aged | Caprylates - administration & dosage | Caprylates - adverse effects | Organoplatinum Compounds - adverse effects | Lymphopenia - chemically induced | Enzymes | Medical colleges | Care and treatment | Metastasis | Antineoplastic agents | Cells | Antimitotic agents | Cancer patients | Chemotherapy | Pancreatic cancer | Physiological aspects | Product development | Cancer
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 01/2014, Volume 32, Issue 2, pp. 76 - 82
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 6, pp. 792 - 802
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 07/2010, Volume 28, Issue 19, pp. 3167 - 3175
Journal Article
Journal of the Neurological Sciences, ISSN 0022-510X, 2012, Volume 323, Issue 1, pp. 167 - 172
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 18, pp. 2493 - 2498
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 9, p. e23379
Background: Tuberous sclerosis (TSC) related tumors are characterized by constitutively activated mTOR signaling due to mutations in TSC1 or TSC2. Methods: We... 
MAMMALIAN TARGET | COMPLEX | PULMONARY LYMPHANGIOLEIOMYOMATOSIS | MOUSE MODEL | BIOLOGY | LUNG-FUNCTION | IMPROVED SURVIVAL | GROWTH FACTOR-D | RAPAMYCIN ANALOG CCI-779 | MUTATIONAL ANALYSIS | RENAL-CELL CARCINOMA | Sirolimus - therapeutic use | Humans | Kidney Neoplasms - chemically induced | Middle Aged | Liver Neoplasms - chemically induced | Male | Kidney Neoplasms - metabolism | Young Adult | Anti-Bacterial Agents - therapeutic use | Vascular Endothelial Growth Factor D - metabolism | Tuberous Sclerosis - drug therapy | Tuberous Sclerosis - metabolism | Adolescent | Liver Neoplasms - metabolism | Angiomyolipoma - chemically induced | Adult | Female | Aged | Anti-Bacterial Agents - adverse effects | Angiomyolipoma - metabolism | Sirolimus - adverse effects | Care and treatment | Hypercholesterolemia | Brain tumors | Liver | Tuberous sclerosis | Rapamycin | Vascular endothelial growth factor | Brain | Respiratory function | Brain cancer | Correlation coefficients | TSC1 protein | Bone marrow | Bioindicators | Angiomyolipoma | Neutropenia | Anemia | Patients | Children & youth | TSC2 protein | Stomatitis | Hospitals | Cysts | Lymphopenia | Correlation analysis | Kidney cancer | Biomarkers | Adults | Mutation | Kidney transplantation | TOR protein | Tuberous sclerosis 2 protein | Headache | Transplants & implants | Sirolimus | Toxicity | Genes | Hamartin | Kinases | Confidence intervals | Pain | Quality | Children | Correlation coefficient | Genetic disorders | Statistical analysis | Kidneys | Regression | Signaling | Lungs | Womens health | Hypertriglyceridemia | Collaboration | Proteinuria | Tumors
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 12/2018, Volume 43, Issue 13, pp. 2597 - 2605
In humans, depression is often associated with low-grade inflammation, activation of the tryptophan/kynurenine pathway, and mild lymphopenia. Preclinical... 
CELLS | PSYCHIATRY | BEHAVIOR | INDOLEAMINE 2,3-DIOXYGENASE |