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lysine-trna ligase - metabolism (226) 226
lysine-trna ligase - genetics (104) 104
biochemistry & molecular biology (98) 98
humans (84) 84
molecular sequence data (80) 80
animals (79) 79
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amino acyl-trna synthetases - metabolism (63) 63
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transfer rna (52) 52
base sequence (44) 44
lysine - metabolism (44) 44
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research (40) 40
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proteins (32) 32
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trna (31) 31
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lysyl-trna synthetase (28) 28
aminoacyl-trna synthetases (27) 27
cell biology (27) 27
substrate specificity (27) 27
protein biosynthesis (26) 26
rna, transfer - metabolism (26) 26
rats (25) 25
amino acyl-trna synthetases - genetics (23) 23
enzymes (23) 23
lysine (23) 23
complex (22) 22
recognition (22) 22
aminoacylation (21) 21
binding (21) 21
liver - enzymology (21) 21
lysine - analogs & derivatives (21) 21
adenosine triphosphate - metabolism (20) 20
biophysics (20) 20
nucleic acid conformation (20) 20
research article (20) 20
rna, transfer, lys - genetics (20) 20
analysis (19) 19
escherichia coli (19) 19
physiological aspects (19) 19
saccharomyces cerevisiae - enzymology (19) 19
rna, transfer, lys - chemistry (18) 18
sequence alignment (18) 18
sequence homology, amino acid (18) 18
acylation (17) 17
article (17) 17
cloning, molecular (17) 17
escherichia coli - metabolism (17) 17
immunodeficiency-virus type-1 (17) 17
molecular weight (17) 17
protein structure, tertiary (17) 17
rna, transfer, amino acyl - metabolism (17) 17
translation (17) 17
amino acids (16) 16
aminoacyl-trna synthetase (16) 16
protein (16) 16
crystallography, x-ray (15) 15
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lysine-trna ligase - antagonists & inhibitors (14) 14
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mice (14) 14
microbiology (14) 14
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biological sciences (13) 13
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structure-activity relationship (13) 13
anticodon (12) 12
evolution, molecular (12) 12
gag (12) 12
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genetic-code (12) 12
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Journal of Cell Biology, ISSN 0021-9525, 07/2017, Volume 216, Issue 7, pp. 2201 - 2216
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2013, Volume 49, Issue 1, pp. 30 - 42
Journal Article
Journal Article
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 07/2013, Volume 93, Issue 1, pp. 132 - 140
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81734
Twenty different aminoacyl-tRNA synthetases (ARSs) link each amino acid to their cognate tRNAs. Individual ARSs are also associated with various non-canonical... 
BREAST-CANCER | TARGET | SIGNAL | AIMP2 | PROTEIN INTERACTIONS | FANCD2 | INTERACTS | MULTIDISCIPLINARY SCIENCES | C-MYC | ASSIGNMENT | TRANSLATION | Humans | Molecular Sequence Data | Neoplasm Proteins - metabolism | Cytokines - chemistry | Mass Spectrometry | HEK293 Cells | Carrier Proteins - chemistry | Amino Acyl-tRNA Synthetases - chemistry | Amino Acyl-tRNA Synthetases - metabolism | Amino Acid Sequence | Computational Biology - methods | Threonine-tRNA Ligase - analysis | Cytokines - metabolism | RNA-Binding Proteins - chemistry | Neoplasm Proteins - chemistry | Nuclear Proteins | Protein Interaction Mapping - methods | Algorithms | Carrier Proteins - metabolism | Chromatography, Affinity | Threonine-tRNA Ligase - isolation & purification | Lysine-tRNA Ligase - metabolism | Protein Processing, Post-Translational | RNA-Binding Proteins - metabolism | Threonine-tRNA Ligase - metabolism | Physiological aspects | Usage | Research | Aminoacyl-tRNA synthetases | Mass spectrometry | Multiple sclerosis | Biomedical research | Peptides | Amino acids | Kinases | Proteins | Signal transduction | Cell growth | Tumor necrosis factor-TNF | Life sciences | Spectroscopy | Purification | tRNA | Threonine-tRNA ligase | Cloning | Mass spectroscopy | Topology | Precipitates | Computer science | Contaminants | Affinity | Scientific imaging | Autoimmune diseases | Aminoacyl-tRNA ligase | Cancer | Apoptosis
Journal Article
Journal Article
Methods, ISSN 1046-2023, 01/2017, Volume 113, pp. 56 - 63
Lysyl-tRNA synthetase (KRS) is an enzyme that conjugates lysine to its cognate tRNAs in the process of protein synthesis. In addition to its catalytic... 
Laminin receptor | Cancer metastasis | Lysyl-tRNA synthetase | Fragment-based drug discovery | Protein–protein interaction | Nuclear magnetic resonance (NMR) | CELLS | LIGAND-BINDING | Protein-protein interaction | MACROMOLECULES | NMR-SPECTROSCOPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | RELAXATION | Receptors, Laminin - metabolism | Small Molecule Libraries - pharmacology | Anticodon - metabolism | Humans | Anticodon - chemistry | Drug Discovery - methods | Receptors, Laminin - chemistry | Receptors, Laminin - genetics | Lysine-tRNA Ligase - antagonists & inhibitors | Nuclear Magnetic Resonance, Biomolecular | Antineoplastic Agents - pharmacology | Lysine - metabolism | Lysine-tRNA Ligase - chemistry | Protein Interaction Domains and Motifs | Binding Sites | RNA, Transfer, Lys - metabolism | Recombinant Proteins - metabolism | Lysine-tRNA Ligase - genetics | Receptors, Laminin - antagonists & inhibitors | Transfer RNA Aminoacylation | Gene Expression | Escherichia coli - enzymology | Enzyme Inhibitors - pharmacology | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | RNA, Transfer, Lys - genetics | Amino Acid Motifs | High-Throughput Screening Assays | Escherichia coli - genetics | Protein Binding | Lysine-tRNA Ligase - metabolism | Laminin | Ligases | Analysis | Methods | Transfer RNA | Oncology, Experimental | Drugstores | Nuclear magnetic resonance spectroscopy | Protein biosynthesis | Metastasis | Research | Lysine | Pharmacy | Drug discovery | Cancer
Journal Article
Journal Article