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lysosomal-associated membrane protein 2 - metabolism (35) 35
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lysosomes - metabolism (29) 29
autophagy (27) 27
cell biology (27) 27
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lysosomal-associated membrane protein 1 - metabolism (25) 25
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lysosomal-associated membrane protein 2 - genetics (17) 17
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microtubule-associated proteins - metabolism (16) 16
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lysosome-associated membrane glycoproteins - metabolism (12) 12
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lysosomal-associated membrane protein 2 - antagonists & inhibitors (8) 8
medicine (8) 8
mice, inbred c57bl (8) 8
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calcium (7) 7
cell survival - drug effects (7) 7
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endosomes - metabolism (7) 7
hela cells (7) 7
lysosomal-associated membrane protein 1 - genetics (7) 7
macrophages (7) 7
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science (7) 7
tor serine-threonine kinases - metabolism (7) 7
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abridged index medicus (6) 6
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autophagy-related protein 5 (6) 6
blotting, western (6) 6
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alpha-synuclein - metabolism (5) 5
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Circulation, ISSN 0009-7322, 06/2012, Volume 125, Issue 25, pp. 3170 - 3181
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 06/2011, Volume 300, Issue 6, pp. H2261 - H2271
Kanamori H, Takemura G, Goto K, Maruyama R, Ono K, Nagao K, Tsujimoto A, Ogino A, Takeyama T, Kawaguchi T, Watanabe T, Kawasaki M, Fujiwara T, Fujiwara H,... 
Infarct size | Ischemia | Metabolism | Ultrastructure | APOPTOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | CARDIAC MYOCYTES | HEART-FAILURE | SIZE | REPERFUSION | MODEL | CARDIOMYOCYTES | ultrastructure | STARVATION-INDUCED AUTOPHAGY | ischemia | CELL-DEATH | infarct size | IN-VIVO | PERIPHERAL VASCULAR DISEASE | metabolism | Myocardial Ischemia - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Male | Autophagy - physiology | Green Fluorescent Proteins - genetics | Autophagy - drug effects | Coronary Occlusion - complications | Macrolides - pharmacology | Myocardial Ischemia - physiopathology | Models, Animal | Myocardial Infarction - physiopathology | Myocardial Infarction - etiology | Green Fluorescent Proteins - metabolism | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Mice, Transgenic | Microtubule-Associated Proteins - antagonists & inhibitors | Myocardial Infarction - metabolism | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Autophagy-Related Protein 5 | Myocytes, Cardiac - metabolism | Mice | Lysosomal-Associated Membrane Protein 2 - antagonists & inhibitors | Lysosomal-Associated Membrane Protein 2 - metabolism | Autophagy (Cytology) | RNA | Physiological aspects | Genetic aspects | Research | Health aspects | Heart attack | Coronary arteries | Heart attacks | Autophagy | Coronary vessels | Adenosine triphosphatase | Index Medicus
Journal Article
Experimental Cell Research, ISSN 0014-4827, 02/2015, Volume 331, Issue 1, pp. 211 - 222
Journal Article
Cell Death and Disease, ISSN 2041-4889, 05/2013, Volume 4, Issue 5, pp. e628 - e628
The purine analog fludarabine (Fd) is an essential therapeutic for chronic lymphocytic leukemia (CLL). Innate or acquired resistance to Fd is a significant... 
BECN1 | Fludarabine resistance | Autophagy | MCL-1 | BIM | APOPTOSIS | autophagy | PHOSPHORYLATION | DEATH | fludarabine resistance | CELL BIOLOGY | BCL-2 | CHRONIC LYMPHOCYTIC-LEUKEMIA | CYTOCHROME-C RELEASE | CASPASE ACTIVATION | UP-REGULATION | EXPRESSION | AMP-Activated Protein Kinases - metabolism | Apoptosis - drug effects | Humans | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Autophagy - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | RNA Interference | Apoptosis Regulatory Proteins - genetics | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Beclin-1 | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Ubiquitin-Activating Enzymes - genetics | Adenine - analogs & derivatives | Membrane Proteins - genetics | Lysosomal-Associated Membrane Protein 2 - genetics | Proto-Oncogene Proteins - genetics | Adenine - pharmacology | Vidarabine - analogs & derivatives | Vidarabine - therapeutic use | Ubiquitin-Activating Enzymes - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Apoptosis Regulatory Proteins - metabolism | Vidarabine - pharmacology | Autophagy-Related Protein 7 | Membrane Proteins - antagonists & inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Myeloid Cell Leukemia Sequence 1 Protein | Ubiquitin-Activating Enzymes - antagonists & inhibitors | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Binding | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Lysosomal-Associated Membrane Protein 2 - antagonists & inhibitors | Lysosomal-Associated Membrane Protein 2 - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Original
Journal Article
Cell Death and Disease, ISSN 2041-4889, 02/2013, Volume 4, Issue 2, pp. e486 - e486
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2018, Volume 496, Issue 2, pp. 294 - 301
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 10/2018, Volume 49, Issue 5, pp. 1999 - 2011
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 11/2011, Volume 301, Issue 5, pp. H2028 - H2037
Han WQ, Xia M, Zhang C, Zhang F, Xu M, Li NJ, Li PL. SNARE-mediated rapid lysosome fusion in membrane raft clustering and dysfunction of bovine coronary... 
Coronary vasorelaxation | Exocy-tosis | Soluble N-ethylmaleimide-sensitive factor attachment protein | Vesicle fusion | Molecular trafficking | NADPH OXIDASE | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | coronary vasorelaxation | molecular trafficking | REDOX SIGNALING PLATFORMS | QUANTITATIVE COLOCALIZATION | vesicle fusion | LIPID RAFTS | soluble N-ethylmaleimide-sensitive factor attachment protein | SYNAPTIC VESICLE DOCKING | PERIPHERAL VASCULAR DISEASE | exocytosis | SMOOTH-MUSCLE-CELLS | GROWTH-FACTOR | ACID SPHINGOMYELINASE | PROTEINS | Immunohistochemistry | Fas Ligand Protein - metabolism | Immunoprecipitation | Membrane Microdomains - metabolism | Coronary Vessels - physiopathology | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Vesicle-Associated Membrane Protein 2 - antagonists & inhibitors | Vesicle-Associated Membrane Protein 2 - genetics | Coronary Vessels - metabolism | Dose-Response Relationship, Drug | Lysosomes - metabolism | RNA Interference | Time Factors | Cattle | Superoxides - metabolism | Fluorescence Resonance Energy Transfer | Bradykinin - pharmacology | Membrane Fusion - drug effects | Lysosomes - drug effects | Coronary Vessels - drug effects | Vasodilator Agents - pharmacology | Endothelial Cells - metabolism | Cells, Cultured | Endothelium, Vascular - physiopathology | Tetanus Toxin - pharmacology | Protein Transport | Microscopy, Confocal | Animals | Endothelium, Vascular - metabolism | Membrane Microdomains - drug effects | Qa-SNARE Proteins - metabolism | Lysosomal-Associated Membrane Protein 1 - metabolism | Vasodilation - drug effects | Vesicle-Associated Membrane Protein 2 - metabolism | Endothelial Cells - drug effects | Physiological aspects | Lysosomes | Health aspects | Membrane proteins | Coronary arteries | Endothelium | Membranes | Coronary vessels | Cells | Index Medicus | Integrative Cardiovascular Physiology and Pathophysiology
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 01/2014, Volume 21, Issue 1, pp. 79 - 91
The immunogenic demise of cancer cells can be induced by various chemotherapeutics, such as anthracyclines and oxaliplatin, and provokes an immune response... 
quinacrine | apoptosis | U2OS cells | caspases | endoplasmic reticulum stress | Beclin 1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | AUTOPHAGY | CLEAVAGE | CHEMOTHERAPY | CELL BIOLOGY | CALRETICULIN EXPOSURE | PANNEXIN 1 | ASSAYS | FIND-ME SIGNAL | Connexins - antagonists & inhibitors | RNA-Binding Proteins - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Cell Death - immunology | rho-Associated Kinases - antagonists & inhibitors | Antineoplastic Agents - toxicity | DNA-Binding Proteins - metabolism | Lysosomes - metabolism | Lysosomal-Associated Membrane Protein 1 - genetics | Myosin Type II - metabolism | RNA Interference | rho-Associated Kinases - metabolism | Adenosine Triphosphate - metabolism | HMGB1 Protein - metabolism | Cell Membrane - metabolism | Cell Death - drug effects | RNA-Binding Proteins - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | Connexins - genetics | rho-Associated Kinases - genetics | Lysosomal-Associated Membrane Protein 1 - antagonists & inhibitors | Microtubule-Associated Proteins - antagonists & inhibitors | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Connexins - metabolism | Nerve Tissue Proteins - metabolism | Animals | Autophagy-Related Protein 5 | Cell Line, Tumor | Lysosomal-Associated Membrane Protein 1 - metabolism | Mice | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Original Paper
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 33, pp. 13599 - 13614
Autophagy comprises the processes of autophagosome synthesis and lysosomal degradation. In certain stress conditions, increased autophagosome synthesis may be... 
APOPTOSIS | COMPLEX | BECLIN 1 | INHIBITION | INTERACTING PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACROAUTOPHAGY | MATURATION | HUNTINGTONS-DISEASE | CELL-DEATH | PARKINSONS-DISEASE | Neurons - pathology | TOR Serine-Threonine Kinases - metabolism | Vesicular Transport Proteins - metabolism | Humans | Green Fluorescent Proteins - genetics | Recombinant Fusion Proteins - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Vesicular Transport Proteins - antagonists & inhibitors | Lysosomes - metabolism | Neurons - ultrastructure | TOR Serine-Threonine Kinases - genetics | RNA Interference | HEK293 Cells | Qa-SNARE Proteins - genetics | Lysosomes - pathology | Neurons - metabolism | Tumor Cells, Cultured | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | Nerve Tissue Proteins - antagonists & inhibitors | Lysosome-Associated Membrane Glycoproteins - metabolism | Cell Survival | Lysosomal-Associated Membrane Protein 2 - genetics | Vesicular Transport Proteins - genetics | Cells, Cultured | Autophagosomes - metabolism | Recombinant Fusion Proteins - chemistry | Nerve Tissue Proteins - genetics | Autophagosomes - pathology | Autophagosomes - ultrastructure | Mice, Knockout | Lysosomes - ultrastructure | Nerve Tissue Proteins - metabolism | Animals | Embryo, Mammalian - cytology | Qa-SNARE Proteins - metabolism | Cell Line, Tumor | Lysosome-Associated Membrane Glycoproteins - genetics | Qa-SNARE Proteins - antagonists & inhibitors | Mice | Lysosomal-Associated Membrane Protein 2 - metabolism | Index Medicus | autophagy | neurodegenerative disease | cell death | lysosome | Cell Biology | mTOR complex (mTORC)
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0124355 - e0124355
Cucurbitacins, the natural triterpenoids possessing many biological activities, have been reported to suppress the mTORC1/p70S6K pathway and to induce... 
ACTIN AGGREGATION | CELLS | APOPTOSIS | ACTIVATED PROTEIN-KINASE | PHOSPHORYLATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | GROWTH | P62/SQSTM1 | CANCER | COFILIN | RNA, Small Interfering - genetics | AMP-Activated Protein Kinases - metabolism | Triterpenes - pharmacology | Microtubule-Associated Proteins - genetics | TOR Serine-Threonine Kinases - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Multiprotein Complexes - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy - drug effects | Autophagy-Related Protein-1 Homolog | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Lysosomes - metabolism | TOR Serine-Threonine Kinases - genetics | MCF-7 Cells | Phosphorylation - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Lysosomes - drug effects | Cell Survival - drug effects | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Ribosomal Protein S6 Kinases, 70-kDa - antagonists & inhibitors | Lysosomal-Associated Membrane Protein 2 - genetics | Protein-Serine-Threonine Kinases - genetics | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Microtubule-Associated Proteins - antagonists & inhibitors | Autophagy-Related Protein 5 | Cell Line, Tumor | HeLa Cells | Antineoplastic Agents, Phytogenic - pharmacology | AMP-Activated Protein Kinases - genetics | Lysosomal-Associated Membrane Protein 2 - metabolism | RNA, Small Interfering - metabolism | Molecular mechanics | Cytoskeleton | Research | Protein kinases | Analysis | Cucurbitaceae | TOR protein | Phosphorylation | Triterpenoids | Homeostasis | Activation | Kinases | Autophagy | Substrates | Recruitment | Signaling | Penicillin | Life sciences | Human behavior | Adapter proteins | Phagocytosis | Cancer | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2011, Volume 121, Issue 1, pp. 37 - 56
Journal Article