X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1130) 1130
index medicus (1056) 1056
apoptosis (691) 691
cell line, tumor (599) 599
apoptosis - drug effects (544) 544
m phase cell cycle checkpoints - drug effects (515) 515
cell cycle (500) 500
animals (458) 458
g2 phase cell cycle checkpoints - drug effects (425) 425
cell biology (409) 409
cancer (408) 408
oncology (380) 380
cell proliferation - drug effects (354) 354
biochemistry & molecular biology (329) 329
phosphorylation (295) 295
antineoplastic agents - pharmacology (287) 287
mice (263) 263
proteins (257) 257
female (249) 249
g2/m arrest (246) 246
analysis (201) 201
dna damage (197) 197
mitosis (195) 195
activation (193) 193
kinases (190) 190
cell cycle proteins - metabolism (183) 183
cell survival - drug effects (174) 174
expression (173) 173
pharmacology & pharmacy (169) 169
flow cytometry (157) 157
signal transduction - drug effects (157) 157
cell cycle - drug effects (154) 154
research (153) 153
article (150) 150
signal transduction (145) 145
dna-damage (144) 144
chemotherapy (138) 138
p53 (138) 138
male (135) 135
inhibition (133) 133
protein-serine-threonine kinases - metabolism (133) 133
in-vitro (132) 132
hela cells (125) 125
m phase cell cycle checkpoints (125) 125
gene expression (120) 120
growth (120) 120
cytotoxicity (119) 119
g2 phase - drug effects (118) 118
chemistry, medicinal (116) 116
tumor suppressor protein p53 - metabolism (116) 116
dose-response relationship, drug (114) 114
deoxyribonucleic acid--dna (112) 112
biology (110) 110
cell proliferation (110) 110
cancer therapies (109) 109
reactive oxygen species - metabolism (107) 107
antineoplastic agents, phytogenic - pharmacology (106) 106
cell division (106) 106
research article (105) 105
care and treatment (103) 103
tumors (103) 103
death (102) 102
cell cycle checkpoints - drug effects (97) 97
cell division - drug effects (97) 97
proliferation (96) 96
cdc2 protein kinase - metabolism (95) 95
antineoplastic agents - chemistry (94) 94
protein (94) 94
cancer cells (91) 91
genetics & heredity (91) 91
mitosis - drug effects (91) 91
dna (90) 90
multidisciplinary sciences (90) 90
genetic aspects (89) 89
health aspects (89) 89
blotting, western (88) 88
m arrest (88) 88
toxicology (87) 87
cell-cycle (86) 86
breast cancer (85) 85
cancer-cells (85) 85
cell growth (85) 85
physiological aspects (85) 85
rna interference (85) 85
cell death (84) 84
spindle assembly checkpoint (84) 84
caspase 3 - metabolism (81) 81
cell cycle proteins - genetics (81) 81
cell line (81) 81
cycle arrest (81) 81
dna repair (81) 81
medicine (81) 81
cells (80) 80
kinase (80) 80
gene expression regulation, neoplastic - drug effects (79) 79
induction (79) 79
down-regulation (78) 78
life sciences (78) 78
mutation (77) 77
mice, nude (76) 76
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (76) 76
UofT at Mississauga - Stacks (35) 35
Collection Dvlpm't (Acquisitions) - Vendor file (33) 33
UofT at Scarborough - Stacks (33) 33
Trinity College (John W Graham) - Stacks (19) 19
Gerstein Science - Stacks (14) 14
St. Michael's College (John M. Kelly) - 2nd Floor (13) 13
UTL at Downsview - May be requested (9) 9
Collection Dvlpm't (Acquisitions) - Closed Orders (8) 8
Victoria University E.J. Pratt - Stacks (6) 6
New College (Ivey) - Stacks (5) 5
St. Michael's Hospital - Stacks (3) 3
Engineering & Comp. Sci. - Stacks (2) 2
Robarts - Reference (2) 2
St. Michael's College (John M. Kelly) - 3rd Floor (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (2) 2
Trinity College (John W Graham) - Reference (2) 2
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Credit Valley Hospital - Reference (1) 1
Criminology - Stacks (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reference (1) 1
OISE - Stacks (1) 1
Online Resources - Online (1) 1
Robarts - May be requested in 6-10 wks (1) 1
Robarts - Not Returned (1) 1
Robarts - Searching (1) 1
Robarts - Storage (1) 1
Royal Ontario Museum - Stacks (1) 1
Scarborough Hospital - Birchmount (1) 1
St. Augustine's Seminary - Stacks (1) 1
St. Michael's College (John M. Kelly) - Missing (1) 1
St. Michael's Hospital - Circulation Desk (1) 1
Trillium Health Centre - Stacks (1) 1
University College (Laidlaw) - May be requested in 6-10 wks (1) 1
UofT at Mississauga - Reference (1) 1
Victoria University E.J. Pratt - Reference (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1649) 1649
French (19) 19
Spanish (7) 7
Chinese (3) 3
German (2) 2
Japanese (2) 2
Russian (2) 2
Czech (1) 1
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e62082
Some potent chemotherapy drugs including tubulin-binding agents had been developed from nature plants, such as podophyllotoxin and paclitaxel. However, poor... 
MITOSIS | ANTIMITOTIC ACTIVITY | MICROTUBULES | NATURAL-PRODUCTS | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | RESISTANCE | TUBULIN | BINDING AGENTS | EXPRESSION | KINASES | Lung Neoplasms - drug therapy | Podophyllotoxin - pharmacology | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Apoptosis - genetics | Endoplasmic Reticulum Stress - genetics | Microtubules - metabolism | Podophyllotoxin - toxicity | Drug Evaluation, Preclinical | Disease Models, Animal | DNA Damage - drug effects | Lung Neoplasms - genetics | M Phase Cell Cycle Checkpoints - drug effects | Endoplasmic Reticulum Stress - drug effects | Antineoplastic Agents, Phytogenic - toxicity | Xenograft Model Antitumor Assays | Animals | Mitosis - drug effects | Signal Transduction - drug effects | Tumor Burden - drug effects | Cell Cycle Checkpoints - drug effects | Models, Biological | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Protein Multimerization - drug effects | Podophyllotoxin - analogs & derivatives | Chemotherapy | Podophyllotoxin | Analysis | Lung cancer | Polymerization | Stress (Physiology) | Tubulins | Health aspects | Apoptosis | Cancer | Drugs | Flow cytometry | Toxicity | Mitosis | Leukemia | DNA damage | Cytotoxicity | Selectivity | Drug development | Kinases | Cancer therapies | Anticancer properties | Metastases | Proteins | Signal transduction | Tubulin | Paclitaxel | Xenografts | Cell cycle | Inhibition | Stains | Deoxyribonucleic acid--DNA | Stresses | Plants (botany) | Hematology | Injection | Survivin | Tumor cell lines | Gene expression | Stress | Aurora B protein | Signaling | Side effects | Cell lines | Colonization | Deoxyribonucleic acid | DNA
Journal Article
Toxicology Letters, ISSN 0378-4274, 05/2013, Volume 219, Issue 1, pp. 8 - 17
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 10/2017, Volume 216, Issue 10, pp. 3097 - 3115
The mechanisms by which neoplastic cells tolerate oncogene-induced DNA replication stress are poorly understood. Cyclin-dependent kinase 2 (CDK2) is a major... 
STRUCTURED DNA | STALLED REPLICATION | CANCER DEVELOPMENT | PCNA MONOUBIQUITINATION | PIGMENTOSUM VARIANT CELLS | GENOME INTEGRITY | TRANSLESION SYNTHESIS | INDUCED SENESCENCE | S-PHASE CHECKPOINT | DAMAGE BYPASS | CELL BIOLOGY | Neoplasms - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | M Phase Cell Cycle Checkpoints - genetics | Drug Resistance, Neoplasm | DNA-Directed DNA Polymerase - genetics | Tumor Suppressor Protein p53 - genetics | Cell Cycle Proteins - antagonists & inhibitors | DNA Breaks, Single-Stranded | DNA-Binding Proteins - metabolism | Protein-Tyrosine Kinases - genetics | DNA, Neoplasm - biosynthesis | G2 Phase Cell Cycle Checkpoints - drug effects | Neoplasms - genetics | Cell Cycle Proteins - genetics | Nuclear Proteins - genetics | Pyrazoles - pharmacology | A549 Cells | Cyclin-Dependent Kinase 2 - metabolism | M Phase Cell Cycle Checkpoints - drug effects | Signal Transduction | Cell Cycle Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | Cyclin-Dependent Kinase 2 - genetics | Nuclear Proteins - metabolism | Pyrimidines - pharmacology | DNA-Binding Proteins - genetics | Neoplasms - drug therapy | G2 Phase Cell Cycle Checkpoints - genetics | Animals | Nuclear Proteins - antagonists & inhibitors | Mice | DNA, Neoplasm - genetics | DNA-Directed DNA Polymerase - metabolism | Ubiquitin-Protein Ligases - genetics | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 12/2017, Volume 118, Issue 12, pp. 4575 - 4586
ABSTRACT Chondrosarcoma is the second most malignant bone tumor with poor prognosis and limited treatment options. Thus, development of more effective... 
ANDROGRAPHOLIDE | APOPTOSIS | TCF‐1 | SOX9 | CELL CYCLE ARREST | CHONDROSARCOMA | TCF-1 | TRANSCRIPTIONAL ACTIVATION | PROTEASOMAL DEGRADATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | SARCOMA-CELLS | WNT/BETA-CATENIN | PATHWAY | PROSTATE-CANCER | BONE | MASTER REGULATOR | CHONDROGENESIS | Diterpenes - pharmacology | SOX9 Transcription Factor - metabolism | M Phase Cell Cycle Checkpoints - drug effects | Apoptosis - drug effects | Humans | M Phase Cell Cycle Checkpoints - genetics | Cell Cycle Proteins - metabolism | Neoplasm Proteins - metabolism | Bone Neoplasms - pathology | Chondrosarcoma - drug therapy | Bone Neoplasms - metabolism | T Cell Transcription Factor 1 - genetics | G2 Phase Cell Cycle Checkpoints - genetics | G2 Phase Cell Cycle Checkpoints - drug effects | Chondrosarcoma - metabolism | Cell Cycle Proteins - genetics | Cell Line, Tumor | Chondrosarcoma - genetics | Chondrosarcoma - pathology | Bone Neoplasms - genetics | Bone Neoplasms - drug therapy | Neoplasm Proteins - genetics | T Cell Transcription Factor 1 - metabolism | SOX9 Transcription Factor - genetics | Medicinal plants | RNA | Proteolysis | Medicine, Botanic | Cell cycle | Heat shock proteins | Medicine, Herbal | T cells | Apoptosis | Plants (botany) | Regulators | Chondrosarcoma | Sox9 protein | Tcf protein | Bone tumors | Lymphocytes T | Gene expression | Cyclins | Anticancer properties | Localization | Hepatocyte nuclear factor 1 | Catenin | Cancer
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/2012, Volume 692, Issue 1-3, pp. 19 - 28
Journal Article