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Current Biology, ISSN 0960-9822, 10/2015, Volume 25, Issue 20, pp. R1002 - R1018
Journal Article
Current Biology, ISSN 0960-9822, 11/2012, Volume 22, Issue 22, pp. R966 - R980
Journal Article
Journal of Nutritional Biochemistry, ISSN 0955-2863, 04/2009, Volume 20, Issue 4, pp. 285 - 290
We studied the effects of apigenin on the cell cycle distribution and apoptosis of human breast cancer cells and explored the mechanisms underlying these... 
CDK1 | SK-BR-3 cells | Apigenin | M phase | Apoptosis | p53
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 10/2019, Volume 83, Issue 10, pp. 1912 - 1923
Cantharidin (CTD), a sesquiterpenoid bioactive substance, has been reported to exhibit anticancer activity against various types of cancer cells. The aim of... 
Cantharidin | 2 | M phase arrest | cell cycle | osteosarcoma U-2 OS cells | G | apoptosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2000, Volume 97, Issue 24, pp. 13103 - 13107
The interface between apoptosis (programmed cell death) and the cell cycle is essential to preserve homeostasis and genomic integrity. Here, we show that... 
CYTOKINESIS | GENE | MULTIDISCIPLINARY SCIENCES | KINASE | M-PHASE | DEATH | INHIBITOR | PROTEINS | PROTEASE | CYCLE | FAMILY
Journal Article
Cancer Letters, ISSN 0304-3835, 2004, Volume 216, Issue 2, pp. 175 - 181
The cytotoxic mechanism of protein-bound polysaccharide isolated from (PL, Mesima ) has been investigated. PL inhibited the proliferation and colony formation... 
Antitumor effect | G2/M phase arrest | Apoptosis | PL
Journal Article
Cancer Letters, ISSN 0304-3835, 2009, Volume 288, Issue 2, pp. 204 - 213
Abstract We investigated the molecular effects of 3,4,2′,4′-tetrahydroxychalcone (butein) treatment in two human hepatoma cancer cell lines–HepG2 and Hep3B.... 
Hematology, Oncology and Palliative Medicine | M phase arrest | JNK | ROS | Apoptosis | Butein | Kinases | Cell cycle | Cancer
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2013, Volume 15, Issue 11, pp. 1378 - 1385
The spindle assembly checkpoint (SAC) is essential in mammalian mitosis to ensure the equal segregation of sister chromatids(1,2). The SAC generates a mitotic... 
CDC20 | MITOSIS | MAD2 | ANAPHASE | DESTRUCTION | MPS1 | CYCLIN-A | CELL-CYCLE | MITOTIC CHECKPOINT | SMALL-MOLECULE INHIBITOR | CELL BIOLOGY | Anaphase-Promoting Complex-Cyclosome | Cell Line | M Phase Cell Cycle Checkpoints | Humans | Spindle Apparatus | Spindle (Cell division) | Gene targeting | Mitosis | Cellular control mechanisms | Genetic aspects | Methods | Testing
Journal Article
by Wang, LH and Jiang, XR and Chen, GL and Guo, W and Zhang, JY and Cui, LJ and Li, HH and Li, M and Liu, X and Yang, JY and Wu, CF
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2016, Volume 6
SL4, a chalcone-based compound, has been shown to retard tumor invasion and angiogenesis by suppressing HIF1 activity and to induce apoptosis by promoting ROS... 
APOPTOSIS | ACTIVATION | CHALCONE DERIVATIVES | G2/M PHASE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | RECEPTOR | ACCUMULATION | HIF-1-ALPHA | INHIBITOR | CYCLE
Journal Article