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Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 3865 - 11
The spindle assembly checkpoint (SAC) is an evolutionarily conserved mechanism, exclusively sensitive to the states of kinetochores attached to microtubules.... 
CDC20 | INACTIVATION | MAD2 | CELLS | OVEREXPRESSION | COMPLEX | KINETOCHORES | INSTABILITY | MULTIDISCIPLINARY SCIENCES | CANCER | SPINDLE-ASSEMBLY CHECKPOINT | Kinetochores | Microtubules | Metaphase | Spatial discrimination | Securin | Stochasticity | Anaphase-promoting complex | Anaphase
Journal Article
Current Biology, ISSN 0960-9822, 01/2019, Volume 29, Issue 1, pp. 104 - 119.e10
Switch-like activation of the spindle assembly checkpoint (SAC) is critical for accurate chromosome segregation and for cell division in a timely manner. To... 
kinetochore | mitosis | spindle assembly checkpoint | cell signaling | eSAC | MPS1 KINASE | CDC20 | MAD2 | RECRUITMENT | ANAPHASE | COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | SWITCH | BINDING | BUB1 | AURORA-B | CELL BIOLOGY
Journal Article
Journal Article
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 05/2019, Volume 127, pp. 143 - 155
Camptothecin (CPT) is a popular therapeutic agent that targets topoisomerase I. Our findings demonstrated that CPT-induced microtubule polymerization results... 
Camptothecin | Topoisomerase I | Tubulin | Mitotic arrest | Mad2 | CANCER-CELLS | APOPTOSIS | PHOSPHORYLATION | FOOD SCIENCE & TECHNOLOGY | P21 | CDC20 | DEGRADATION | CELL-CYCLE | CHECKPOINT | SENESCENCE | TOXICOLOGY | UP-REGULATION | Polymerization | Tubulins | Marine biology
Journal Article
Journal Article