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Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1887 - 1890
β-Endorphin is found in the pituitary with two related peptides, the C′-fragment (β-endorphin 1-27) and the des histidine derivative of the C′-fragment... 
beta-Endorphin | Animals | Pancreas - analysis | Endorphins | Rats | Male | Brain Chemistry | Pituitary Gland - analysis | Chromatography, High Pressure Liquid | Rats, Inbred Strains
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1809 - 1812
The levels of immunoreactive leucine-enkephalin, α-neo-endorphin, dynorphin (1-17) and dynorphin (1-8) have been determined in the hypothalamus and posterior... 
Rats, Brattleboro | Protein Precursors - analysis | Rats | Dynorphins | Male | Hypothalamus - analysis | Endorphins - analysis | Rats, Inbred Strains | Animals | Radioimmunoassay | Female | Enkephalin, Leucine - analysis | Pituitary Gland, Posterior - analysis
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1821 - 1824
Dynorphin and an opiate-inactive fragment des-Tyr-dynorphin produced similar effects on EEG, motor function and hippocampal unit firing. Naloxone had no effect... 
Neural Inhibition | Endorphins - pharmacology | Electrophysiology | Motor Activity - drug effects | Rats | Dynorphins | Male | Hippocampus - drug effects | Rats, Inbred Strains | Seizures - chemically induced | Endorphins - adverse effects | Animals | Naloxone - pharmacology
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1777 - 1780
Analogs of dynorphin-(1-13) with modifications in the enkephalin segment were compared with correspondingly modified analogs of [Leu ] enkephalin in the guinea... 
Brain - metabolism | Animals | Enkephalin, Leucine - analogs & derivatives | Guinea Pigs | Vas Deferens - metabolism | Endorphins | Ileum - metabolism | Rats | Dynorphins | Male | Mice | Structure-Activity Relationship
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1871 - 1873
Plasma Beta-endorphin (B-END) immunoreactivity was measured in 19 men, 16 women at midcycle, and ten pregnant women at various points in their pregnancies.... 
Humans | Pregnancy Complications | Male | Obstetric Labor Complications | Self Disclosure | Blood | Pregnancy | beta-Endorphin | Pain | Adult | Female | Perception | Anxiety | Endorphins - immunology
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1853 - 1856
We have used radioimmunoassays with carboxyl-specific antisera to study the development of met- and leu-enkephalin in rat brain and gut from 13-days of fetal... 
Enkephalin, Methionine - immunology | Animals | Rats | Female | Fetus - immunology | Male | Chromatography, High Pressure Liquid | Enkephalin, Leucine - immunology | Animals, Newborn - immunology | Rats, Inbred Strains | Brain - immunology | Intestines - immunology
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1695 - 1698
Experiments on opiate sensitive peripheral tissue preparations such as the mouse vas deferens and the guinea-pig ileum have demonstrated the ability to induce... 
Brain - drug effects | Ileum - drug effects | Animals | Guinea Pigs | Humans | Drug Tolerance | Rats | Male | Mice | Narcotics - pharmacology | Opioid-Related Disorders - physiopathology | Vas Deferens - drug effects
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1699 - 1702
Compounds that elicit a "quasi-morphine withdrawal syndrome" (QMWS) after acute administration to rats constitute a new class of behavior-modifying agent. In... 
Animals | Substance Withdrawal Syndrome - etiology | Humans | Codeine - adverse effects | Drug Tolerance | Rats | Male | 1-Methyl-3-isobutylxanthine - adverse effects | Codeine - analogs & derivatives | In Vitro Techniques | Rats, Inbred Strains | Morphine - adverse effects
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1879 - 1882
Rats given high doses of colchicine (300-400 ug, i.c.v.) were used to investigate the comparative distribution of Leu-enkephalin and bovine adrenal medullary... 
Immune Sera - immunology | Immunologic Techniques | Rats | Male | Protein Precursors - immunology | Enkephalin, Leucine - immunology | Enkephalin, Methionine - analogs & derivatives | Rats, Inbred Strains | Tissue Distribution | Enkephalin, Methionine - immunology | Animals | Histocytochemistry | Brain Chemistry
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1837 - 1840
We have recently undertaken an extensive examination of the effects of chronic dietary lithium treatment on levels of brain leucine-enkephalin immunoreactivity... 
Tissue Distribution | Analgesia | Animals | Time Factors | Enkephalins - metabolism | Lithium - pharmacology | Rats | Male | Brain Chemistry | Enkephalins - analysis | Rats, Inbred Strains
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1857 - 1860
In the magnocellular cells of the paraventricular nucleus of hypothalamus, corticotropin releasing factor (CRF) immunoreactivity was observed in a... 
Adrenalectomy | Rats, Brattleboro | Paraventricular Hypothalamic Nucleus - cytology | Rabbits | Animals | Neurons - immunology | Rats | Male | Corticotropin-Releasing Hormone - immunology | Vasopressins - immunology | Paraventricular Hypothalamic Nucleus - immunology
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1703 - 1706
While prototype cannabinoid analgetics such as levonantradol do not act at the opiate receptor, their opiate-like properties suggest a proximal site of action.... 
Molecular Conformation | Nociceptors - physiology | Rats | Male | Mice, Inbred Strains | Rats, Inbred Strains | Biomechanical Phenomena | Chemistry | Animals | Chemical Phenomena | Mice | Narcotics - metabolism | Phenanthridines - metabolism | Prostaglandins - metabolism | Receptors, Opioid - metabolism
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1833 - 1836
The present study addresses the possible role of endorphins in mediating the anxiolytic properties of diazepam (DZM) in man. The ability of a low dose (0.4 mg.... 
Anxiety - drug effects | Naloxone - pharmacology | Humans | Adult | Female | Male | Blood Pressure - drug effects | Diazepam - pharmacology
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 16, pp. 1829 - 1832
Immunoreactive (ir) beta-endorphin (b-END) and dynorphin (DYN) in rat brain and pituitary were measured after food and water deprivation and from brains taken... 
Eating | Rats | Drinking | Dynorphins | Male | Hypothalamus - analysis | Circadian Rhythm | Endorphins - analysis | Rats, Inbred Strains | beta-Endorphin | Animals | Food Deprivation | Enkephalins - physiology | Pituitary Gland - analysis
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 20, pp. 2299 - 2302
A method was recently developed by Raffa et al (1) for rapid analysis of brain levels of morphine in rats given the drug subcutaneously. The technique combines... 
Brain - metabolism | Dose-Response Relationship, Drug | Animals | Chromatography, High Pressure Liquid - methods | Injections, Subcutaneous | Drug Tolerance | Morphine - metabolism | Rats | Male | Rats, Inbred Strains | Morphine - administration & dosage | Morphine - isolation & purification
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 20, pp. 2225 - 2228
In both normal and hypophysectomized rats, electroconvulsive shock (ECS) produced a significant postictal rise in seizure threshold (S.T.) to flurothyl, a... 
Anticonvulsants | Animals | Naloxone - pharmacology | Rats | Male | Flurothyl | Hypophysectomy | Bicuculline - pharmacology | Rats, Inbred Strains
Journal Article
Life Sciences, ISSN 0024-3205, 1982, Volume 31, Issue 20, pp. 2257 - 2260
Journal Article
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