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Journal Article
Medical physics (Lancaster), ISSN 0094-2405, 2014, Volume 41, Issue 10, pp. 101903 - n/a
Purpose: Survival for high‐grade gliomas is poor, at least partly explained by intratumoral heterogeneity contributing to treatment resistance... 
ADC | biomedical MRI | Matrix theory | Multivariate analysis | biodiffusion | Digital computing or data processing equipment or methods, specially adapted for specific applications | Cell growth | image enhancement | Involving electronic [emr] or nuclear [nmr] magnetic resonance, e.g. magnetic resonance imaging | Diffusion | tumours | medical image processing | Image registration | Data analysis | Medical imaging | Probability theory, stochastic processes, and statistics | Image enhancement or restoration, e.g. from bit‐mapped to bit‐mapped creating a similar image | Analysis of texture | Spatial analysis | Biological material, e.g. blood, urine; Haemocytometers | image texture | matrix algebra | Image analysis | Magnetic resonance imaging | Image data processing or generation, in general | radiation therapy | glioma | cancer | multivariate image analysis | principal component analysis | texture analysis | DIFFUSION-WEIGHTED MRI | CONTRAST-ENHANCED MRI | PRINCIPAL COMPONENT ANALYSIS | NEWLY-DIAGNOSED GLIOBLASTOMA | FEATURES | HETEROGENEITY | MAPS FDMS | TREATMENT RESPONSE | MALIGNANT GLIOMAS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | BRAIN | Multivariate Analysis | Prognosis | Age Factors | Follow-Up Studies | Glioma - diagnosis | Dacarbazine - therapeutic use | Humans | Image Interpretation, Computer-Assisted - methods | Middle Aged | Brain Neoplasms - pathology | Chemoradiotherapy, Adjuvant | Glioma - radiotherapy | Neoplasm Grading | Glioma - pathology | Dacarbazine - analogs & derivatives | Adult | Brain Neoplasms - radiotherapy | Principal Component Analysis | Brain Neoplasms - diagnosis | Treatment Outcome | Brain - radiation effects | Brain Neoplasms - drug therapy | Disease Progression | Antineoplastic Agents, Alkylating - therapeutic use | Brain - drug effects | Survival Analysis | Brain - pathology | Aged | Diffusion Magnetic Resonance Imaging - methods | Glioma - drug therapy | GLIOMAS | SURGERY | DIAGNOSIS | PATIENTS | IMAGE PROCESSING | NMR IMAGING | BIOLOGICAL MARKERS | RADIOTHERAPY | 60 APPLIED LIFE SCIENCES
Journal Article
Cancer letters, ISSN 0304-3835, 2015, Volume 367, Issue 1, pp. 58 - 68
.... The introduction of temozolomide (TMZ) has advanced chemotherapy for malignant gliomas. However, a considerable number of GBM cases are refractory to TMZ, the need for more effective therapeutic options is overwhelming... 
Hematology, Oncology and Palliative Medicine | NVP-BEZ235 | Cell cycle arrest | PI3K–AKT–mTOR | Temozolomide | Glioma | Apoptosis | PI3K-AKT-mTOR | AKT ACTIVATION | CYCLIN-A | PHOSPHATIDYLINOSITOL 3-KINASE/MAMMALIAN TARGET | PI3K/MTOR INHIBITOR | ADJUVANT TEMOZOLOMIDE | MALIGNANT GLIOMA | PI3K/AKT PATHWAY | ONCOLOGY | RAPAMYCIN INHIBITOR | GLIOBLASTOMA CELLS | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Brain Neoplasms - pathology | Caspase 3 - metabolism | Antineoplastic Agents, Alkylating - pharmacology | Male | Quinolines - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | TOR Serine-Threonine Kinases - antagonists & inhibitors | Dacarbazine - pharmacology | Glioma - pathology | Dacarbazine - analogs & derivatives | Inhibitory Concentration 50 | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Brain Neoplasms - enzymology | Glioma - enzymology | bcl-2-Associated X Protein - metabolism | Imidazoles - pharmacology | Brain Neoplasms - drug therapy | Mice, SCID | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Tumor Burden - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | G1 Phase Cell Cycle Checkpoints - drug effects | Glioma - drug therapy | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Chemotherapy | Antineoplastic agents | Gliomas | Analysis | Cancer
Journal Article
Neuro-oncology (Charlottesville, Va.), ISSN 1523-5866, 2018, Volume 20, Issue 7, pp. 873 - 884
Journal Article
Frontiers in cell and developmental biology, ISSN 2296-634X, 2017, Volume 5, p. 43
Journal Article