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Journal Article
Seminars in Oncology, ISSN 0093-7754, 10/2011, Volume 38, Issue 5, pp. 621 - 626
The 5q-syndrome is a subtype of myelodysplastic syndrome (MDS) with a defined clinical phenotype associated with heterozygous deletions of chromosome 5q. While... 
CELLS | RPS14 | PROTEIN | GENE | ONCOLOGY | MALIGNANT MYELOID DISEASES | 5Q-SYNDROME | MODEL | IDENTIFICATION | REGION | HAPLOINSUFFICIENCY | Chromosome Deletion | Phenotype | Humans | Myelodysplastic Syndromes - genetics | Anemia, Macrocytic - genetics | Disease Progression | Chromosomes, Human, Pair 5 - genetics | Haploinsufficiency
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0169767 - e0169767
An understanding of how each individual 5q chromosome critical deleted region (CDR) gene contributes to malignant transformation would foster the development... 
CANCER-CELLS | TRANSFORMATION | IN-VITRO | COMMONLY DELETED REGION | GENE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION FACTOR EGR-1 | MALIGNANT MYELOID DISEASES | MYELODYSPLASTIC SYNDROME | EXPRESSION | MOLECULAR DELINEATION | Whole-Body Irradiation | Apoptosis - radiation effects | Bone Marrow Cells - cytology | Up-Regulation - radiation effects | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Bone Marrow Cells - radiation effects | RNA, Messenger - metabolism | Tumor Suppressor Protein p53 - genetics | DNA Breaks, Double-Stranded - radiation effects | Tibia - cytology | Animals | Histones - genetics | Early Growth Response Protein 1 - genetics | Mice | Histones - metabolism | Real-Time Polymerase Chain Reaction | Bone Marrow Cells - metabolism | Early Growth Response Protein 1 - metabolism | Microscopy, Fluorescence | Radiation, Ionizing | Ionizing radiation | Growth | Causes of | Physiological aspects | Research | Tumor proteins | Hematopoietic stem cells | Apoptosis | Transformation | Transcription | p53 Protein | Leukemia | Lung cancer | DNA damage | Radiation | Cancer therapies | Neoplasms | Proteins | Toxicology | Immunology | Bone marrow | Genetics | Chromosomes | Deoxyribonucleic acid--DNA | Radiation effects | Medical research | Hematology | EGR-1 protein | Gene expression | Ribonucleic acid--RNA | Hemopoiesis | Signaling | Medical prognosis | Stem cells | Lymphomas | Transformations | Mutation | Bone | Aberration | Prostate | Tumors | Index Medicus | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Journal Article