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European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2019, Volume 177, pp. 221 - 234
Alzheimer's disease (AD) is a multifactorial neurological disorder involving complex pathogenesis. Single target directed drugs proved ineffective and since... 
Acetylcholinesterase inhibitors | Diphenylpyrimidine | MAO inhibitors | Alzheimer's disease | Dual inhibitors | Neurological disorders | Acetylchollnesterase inhibitors | DESIGN | CHEMISTRY, MEDICINAL | ALZHEIMERS-DISEASE | CHOLINESTERASE-INHIBITORS | NEUROPROTECTION | MULTITARGET-DIRECTED LIGANDS | DONEPEZIL | BIOLOGICAL EVALUATION | POTENTIAL TREATMENT | MULTIPOTENT MAO | HYBRIDS | Alkynes - chemical synthesis | Cholinesterase Inhibitors - toxicity | Pyrimidines - chemical synthesis | Humans | Cholinesterase Inhibitors - chemistry | Cholinesterase Inhibitors - chemical synthesis | Structure-Activity Relationship | Monoamine Oxidase Inhibitors - chemical synthesis | Pyrimidines - chemistry | Monoamine Oxidase - chemistry | Pyrimidines - toxicity | Drug Design | Alkynes - pharmacology | Molecular Structure | Monoamine Oxidase Inhibitors - pharmacology | Catalytic Domain | Alzheimer Disease - drug therapy | Alkynes - chemistry | Acetylcholinesterase - chemistry | Pyrimidines - pharmacology | Molecular Dynamics Simulation | Monoamine Oxidase Inhibitors - toxicity | Cholinesterase Inhibitors - pharmacology | Alkynes - toxicity | Cell Line, Tumor | Molecular Docking Simulation | Monoamine Oxidase Inhibitors - chemistry | Kinetics | Oxidases | Molecular dynamics | Development and progression | Nervous system diseases | Enzyme inhibitors
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 2017, Volume 25, Issue 12, pp. 3006 - 3017
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Current Medicinal Chemistry, ISSN 0929-8673, 01/2015, Volume 22, Issue 3, pp. 373 - 404
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1994, 1st ed., Progress in psychiatry., ISBN 9780880484749, Volume no. 43, xvi, 302
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Journal of the American Chemical Society, ISSN 0002-7863, 02/2015, Volume 137, Issue 6, pp. 2366 - 2374
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Journal Article
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European Journal of Medicinal Chemistry, ISSN 0223-5234, 06/2014, Volume 80, pp. 543 - 561
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