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PLoS Computational Biology, ISSN 1553-734X, 2014, Volume 10, Issue 2, p. e1003470
Interleukin-1 (IL-1) is a large cytokine family closely related to innate immunity and inflammation. IL-1 proteins are key players in signaling pathways such... 
DATA-BANK | KINASE | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | INTERFACES | PROTEIN-PROTEIN INTERACTIONS | RECEPTOR | SCALE | MOLECULAR DOCKING | EXPRESSION | SOMATIC MUTATIONS | BRAIN-TUMORS | Interleukin-1 Receptor Accessory Protein - genetics | MAP Kinase Kinase 7 - genetics | Neoplasms - metabolism | Interleukin-1 - genetics | Interleukin-1 Receptor Accessory Protein - chemistry | Humans | MAP Kinase Kinase 7 - chemistry | Mitogen-Activated Protein Kinase 9 - genetics | Mitogen-Activated Protein Kinase 10 - genetics | MAP Kinase Kinase 7 - metabolism | Interleukin-1 Receptor Accessory Protein - metabolism | Receptors, Interleukin-1 Type I - metabolism | Inflammation - metabolism | MAP Kinase Kinase 4 - metabolism | Neoplasms - genetics | Computer Simulation | Receptors, Interleukin-1 Type I - chemistry | Interleukin-1 - chemistry | Oncogenes | Mitogen-Activated Protein Kinase 9 - chemistry | Interleukin-1 - metabolism | Protein Interaction Maps - immunology | Signal Transduction | Mitogen-Activated Protein Kinase 9 - metabolism | Computational Biology | Models, Molecular | Inflammation - immunology | Mitogen-Activated Protein Kinase 10 - metabolism | Mitogen-Activated Protein Kinase 10 - chemistry | Mutagenesis | Protein Interaction Maps - genetics | Models, Biological | Neoplasms - immunology | Receptors, Interleukin-1 Type I - genetics | Inflammation - genetics | MAP Kinase Kinase 4 - chemistry | MAP Kinase Kinase 4 - genetics | Polymorphism, Single Nucleotide | Mutation | Complications and side effects | Interleukin-1 | Patient outcomes | Physiological aspects | Development and progression | Inflammation | Genetic aspects | Research | Risk factors | Genetic polymorphisms | Apoptosis | Proteins | Cytokines | Disease | Kinases | Cancer
Journal Article
The Plant Cell, ISSN 1040-4651, 11/2009, Volume 21, Issue 11, pp. 3506 - 3517
Mitogen-activated protein kinase (MAPK) signaling networks regulate numerous eukaryotic biological processes. In Arabidopsis thaliana, signaling networks that... 
Phenotypes | Developmental biology | Cell lines | Plant epidermis | Guard cells | Epidermis | Gene expression regulation | Physiological regulation | Transgenes | Plant cells | MKK2 | ACTIVATED PROTEIN-KINASE | DIVISIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NETWORKS | CASCADES | PLANT SCIENCES | CELL BIOLOGY | SALT STRESS | PATHWAY | RESISTANCE | DIFFERENTIATION | EXPRESSION | MAP Kinase Kinase 7 - genetics | Meristem - enzymology | Mitogen-Activated Protein Kinase Kinases - genetics | Arabidopsis - enzymology | Cell Proliferation | Arabidopsis - growth & development | Arabidopsis Proteins - metabolism | MAP Kinase Kinase 7 - metabolism | Cell Differentiation - genetics | Mitogen-Activated Protein Kinase Kinases - metabolism | MAP Kinase Signaling System - genetics | Meristem - genetics | Growth Inhibitors - genetics | Cell Lineage - genetics | Plant Stomata - enzymology | Cell Division - genetics | Arabidopsis Proteins - genetics | Gene Expression Regulation, Plant - genetics | Biological Assay - methods | Plant Stomata - growth & development | Meristem - growth & development | Arabidopsis - metabolism | Growth Inhibitors - metabolism | Arabidopsis - genetics | Gene Expression Regulation, Enzymologic - genetics | Mitogen-Activated Protein Kinases - genetics | Body Patterning - genetics | Plant Stomata - genetics | Mitogen-Activated Protein Kinases - metabolism | Arabidopsis thaliana | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Protein kinases
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 21, pp. 17100 - 17108
Naturally occurring Foxp3(+)CD4(+)CD25(+) T regulatory cell (nTreg)-mediated suppression of lung allergic responses is abrogated following ligation of... 
KAPPA-B ACTIVATION | TGF-BETA | PROTEIN | INDUCED TNF RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR FOXP3 | AIRWAY HYPERREACTIVITY | LUNG ALLERGIC RESPONSES | COSTIMULATION | LIGAND | CUTTING EDGE | MAP Kinase Kinase 7 - genetics | T-Lymphocytes, Regulatory - metabolism | Asthma - metabolism | MAP Kinase Signaling System - physiology | Immune Tolerance - physiology | MAP Kinase Kinase 7 - immunology | NF-kappa B - immunology | MAP Kinase Kinase 4 - immunology | NF-kappa B - metabolism | Enzyme Activation - immunology | T-Lymphocytes, Regulatory - immunology | Autoimmune Diseases - genetics | MAP Kinase Kinase 7 - metabolism | Phosphorylation - genetics | MAP Kinase Kinase 4 - metabolism | Asthma - immunology | Female | Lung - metabolism | Phosphorylation - immunology | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Autoimmune Diseases - metabolism | Immune Tolerance - drug effects | Autoimmune Diseases - immunology | Glucocorticoid-Induced TNFR-Related Protein - metabolism | Glucocorticoid-Induced TNFR-Related Protein - genetics | p38 Mitogen-Activated Protein Kinases - genetics | p38 Mitogen-Activated Protein Kinases - immunology | Enzyme Activation - drug effects | Anthracenes - pharmacology | Asthma - genetics | Mice, Knockout | Animals | MAP Kinase Signaling System - drug effects | NF-kappa B - genetics | MAP Kinase Kinase 4 - genetics | Cell Proliferation - drug effects | Glucocorticoid-Induced TNFR-Related Protein - immunology | Mice | Protein Kinase Inhibitors - pharmacology | Enzyme Activation - genetics | Lung - immunology | MAP Kinases (MAPKs) | GITR | Signal Transduction | Cell Signaling | CD4+CD25+Foxp3+ T Regulatory Cells | Cellular Immune Response | Asthma | Jun N-terminal Kinase (JNK) | SP600125
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2014, Volume 33, Issue 16, pp. 1784 - 1801
Journal Article
FASEB Journal, ISSN 0892-6638, 07/2017, Volume 31, Issue 7, pp. 2963 - 2972
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2015, Volume 112, Issue 46, pp. 14284 - 14289
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 12/2009, Volume 29, Issue 24, pp. 6515 - 6526
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL KINASE | COUPLED RECEPTORS | ASPARAGINE SYNTHETASE GENE | JUN NH2-TERMINAL KINASE | ENDOPLASMIC-RETICULUM | INTEGRATED STRESS-RESPONSE | TRANSCRIPTION FACTOR | HISTONE ACETYLATION | SIGNAL-TRANSDUCTION PATHWAY | CELL BIOLOGY | MAP Kinase Kinase 7 - genetics | RNA, Small Interfering - genetics | Transcription Factor CHOP - genetics | Phosphorylation | Humans | Multiprotein Complexes | cdc42 GTP-Binding Protein - metabolism | Mitogen-Activated Protein Kinase 9 - genetics | Activating Transcription Factor 2 - genetics | GTP-Binding Protein alpha Subunits, G12-G13 - metabolism | Gene Knockdown Techniques | Mechanistic Target of Rapamycin Complex 1 | Starvation - metabolism | MAP Kinase Kinase 7 - metabolism | Proteins | Adult | Protein-Serine-Threonine Kinases - metabolism | Activating Transcription Factor 3 - genetics | MAP Kinase Kinase Kinase 1 - metabolism | Cell Line | Promoter Regions, Genetic | Mitogen-Activated Protein Kinase 9 - metabolism | GTP-Binding Protein alpha Subunits, G12-G13 - genetics | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Amino Acids - deficiency | Transcription Factors - genetics | Activating Transcription Factor 3 - metabolism | Activating Transcription Factor 2 - metabolism | Transcription Factors - metabolism | Animals | cdc42 GTP-Binding Protein - genetics | Signal Transduction - physiology | MAP Kinase Kinase Kinase 1 - genetics | Mice | TOR Serine-Threonine Kinases | Enzyme Activation | Transcription Factor CHOP - metabolism | rac1 GTP-Binding Protein - metabolism | RNA, Small Interfering - metabolism | rac1 GTP-Binding Protein - genetics
Journal Article
British Journal of Cancer, ISSN 0007-0920, 02/2011, Volume 104, Issue 4, pp. 664 - 672
BACKGROUND: Aberrant mitogen/extracellular signal-regulated kinase 5 (MEK5)-extracellular signal-regulated protein kinase 5 (ERK5)-mediated signalling has been... 
Prostate cancer; signalling; invasive phenotype | CELLS | TIMP-2 EXPRESSION | TRANSCRIPTION | PROLIFERATION | MATRIX METALLOPROTEINASES | prostate cancer | ONCOLOGY | PATHWAY | GENE-EXPRESSION | MATRIX-METALLOPROTEINASE-9 | invasive phenotype | INHIBITORS | MMP-9 | signalling | MAP Kinase Kinase 5 - physiology | Prostatic Neoplasms - metabolism | MAP Kinase Signaling System - physiology | Prostatic Hyperplasia - pathology | Humans | Male | Transplantation, Heterologous | Cell Movement - genetics | MAP Kinase Signaling System - genetics | Prostatic Neoplasms - genetics | Transfection | MAP Kinase Kinase 5 - metabolism | Benzamides - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Drug Evaluation, Preclinical | Mitogen-Activated Protein Kinase 7 - physiology | Gene Expression Regulation, Neoplastic - genetics | Prostatic Neoplasms - pathology | Neoplasm Invasiveness | RNA, Small Interfering - pharmacology | Cells, Cultured | Mitogen-Activated Protein Kinase 7 - genetics | MAP Kinase Kinase 5 - genetics | Mitogen-Activated Protein Kinase 7 - metabolism | Prostatic Hyperplasia - genetics | Prostatic Hyperplasia - metabolism | Cell Movement - drug effects | Phenotype | Animals | MAP Kinase Signaling System - drug effects | Mice, Nude | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Molecular Diagnostics
Journal Article